Edinburgh Research Explorer

Prof Andrew Leigh-Brown

Professor of Evolutionary Genetics

  1. Article › Research › Peer-reviewed
  2. A Direct Comparison of Two Densely Sampled HIV Epidemics: The UK and Switzerland

    Ragonnet-Cronin, M. L., Shilaih, M., Günthard, H. F., Hodcroft, E. B., Böni, J., Fearnhill, E., Dunn, D., Yerly, S., Klimkait, T., Aubert, V., Yang, W-L., Brown, A. E., Lycett, S. J., Kouyos, R. & Leigh Brown, A., 19 Sep 2016, In : Scientific Reports. 6, 32251.

    Research output: Contribution to journalArticle

  3. A high HIV-1 strain variability in London, UK, revealed by full-genome analysis: Results from the ICONIC project

    Yebra, G., Frampton, D., Gallo Cassarino, T., Raffle, J., Hubb, J., Ferns, R. B., Waters, L., Tong, C. Y. W., Kozlakidis, Z., Hayward, A., Kellam, P., Pillay, D., Clark, D. A., Nastouli, E., Leigh Brown, A. J. & ICONIC Consortium, 1 Feb 2018, In : PLoS ONE. 13, 2, p. e0192081

    Research output: Contribution to journalArticle

  4. A maximum likelihood method for detecting directional evolution in protein sequences and its application to influenza a virus

    Pond, S. L. K., Poon, A. F. Y., Leigh Brown, A. J. & Frost, S. D. W., Oct 2008, In : Molecular Biology and Evolution. 25, 9, p. 1809-1824 16 p.

    Research output: Contribution to journalArticle

  5. Activation by malaria antigens renders mononuclear cells susceptible to HIV infection and re-activates replication of endogenous HIV in cells from HIV-infected adults

    Froebel, K., Howard, W., Schafer, JR., Howie, F., Whitworth, J., Kaleebu, P., Leigh Brown, AJ. & Riley, E., May 2004, In : Parasite Immunology. 26, 5, p. 213-217 5 p.

    Research output: Contribution to journalArticle

  6. Adaptation to Different Human Populations by HIV-1 Revealed by Codon-Based Analyses

    Kosakovsky Pond, S. L., Frost, S. D. W., Grossman, Z., Gravenor, M. B., Richman, D. D. & Leigh Brown, A. J., Jun 2006, In : PLoS Computational Biology. 2, 6, p. 530-538 9 p., e62.

    Research output: Contribution to journalArticle

  7. Adaptation to human populations is revealed by within-host polymorphisms in HIV-1 and hepatitis C virus

    Poon, A. F. Y., Pond, S. L. K., Bennett, P., Richman, D. D., Leigh Brown, A. J. & Frost, S. D. W., Apr 2007, In : Plos pathogens. 3, 3

    Research output: Contribution to journalArticle

  8. An Evolutionary Model-Based Algorithm for Accurate Phylogenetic Breakpoint Mapping and Subtype Prediction in HIV-1

    Pond, S. L. K., Posada, D., Stawiski, E., Chappey, C., Poon, A. F. Y., Hughes, G., Fearnhill, E., Gravenor, M. B., Leigh Brown, A. J. & Frost, S. D. W., 2009, In : PLoS Computational Biology. 5, 11, p. 1-21 21 p., e1000581.

    Research output: Contribution to journalArticle

  9. An individual-based epidemiological model for the transmission of drug resistant HIV

    Leigh Brown, AJ., Frost, SD., Daar, E., Perrin, L., Richman, DD. & Little, SJ., 2002, In : Antiviral Therapy. 7, 1

    Research output: Contribution to journalArticle

  10. Analysing the genotypic basis of hypersusceptibility to amprenavir in HIV from antiretroviral-naive patients

    Leigh Brown, AJ., Good, B., Frost, SD., Collier, AC., Connick, E., Conway, B., Daar, E., Kilby, M., Routy, JP., Margolick, JB., Markowitz, M., Dawson, K., Hellmann, N., Richman, DD. & Little, SJ., 2002, In : Antiviral Therapy. 7, 1

    Research output: Contribution to journalArticle

  11. Analysis of HIV-1 env gene sequences reveals evidence for a low effective number in the viral population

    Leigh Brown, AJ., 1997, In : Proceedings of the National Academy of Sciences. 94, 5, p. 1862-1865 4 p.

    Research output: Contribution to journalArticle

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