Edinburgh Research Explorer

Andrew Leigh-Brown

Professor of Evolutionary Genetics

  1. 2009
  2. Detection of Mammalian Virulence Determinants in Highly Pathogenic Avian Influenza H5N1 Viruses: Multivariate Analysis of Published Data

    Lycett, S. J., Ward, M. J., Lewis, F. I., Poon, A. F. Y., Pond, S. L. K. & Leigh Brown, A., Oct 2009, In : Journal of Virology. 83, 19, p. 9901-9910 10 p.

    Research output: Contribution to journalArticle

  3. Molecular Phylodynamics of the Heterosexual HIV Epidemic in the United Kingdom

    Hughes, G. J., Fearnhill, E., Dunn, D., Lycett, S. J., Rambaut, A. & Leigh Brown, A. J., Sep 2009, In : Plos Pathogens. 5, 9, 8 p., e1000590.

    Research output: Contribution to journalArticle

  4. An Evolutionary Model-Based Algorithm for Accurate Phylogenetic Breakpoint Mapping and Subtype Prediction in HIV-1

    Pond, S. L. K., Posada, D., Stawiski, E., Chappey, C., Poon, A. F. Y., Hughes, G., Fearnhill, E., Gravenor, M. B., Leigh Brown, A. J. & Frost, S. D. W., 2009, In : PLoS Computational Biology. 5, 11, p. 1-21 21 p., e1000581.

    Research output: Contribution to journalArticle

  5. 2008
  6. A maximum likelihood method for detecting directional evolution in protein sequences and its application to influenza a virus

    Pond, S. L. K., Poon, A. F. Y., Leigh Brown, A. J. & Frost, S. D. W., Oct 2008, In : Molecular Biology and Evolution. 25, 9, p. 1809-1824 16 p.

    Research output: Contribution to journalArticle

  7. Genetic basis of variation in tenofovir drug susceptibility in HIV-1

    Murray, R. J., Lewis, F. I., Miller, M. D. & Leigh Brown, A. J., Jun 2008, In : AIDS. 22, 10, p. 1113-1123 11 p.

    Research output: Contribution to journalArticle

  8. Episodic sexual transmission of HIV revealed by molecular phylodynamics

    Lewis, F., Hughes, G. J., Rambaut, A., Pozniak, A. & Leigh Brown, A. J., Mar 2008, In : PLoS Medicine. 5, 3, p. 0392-0402 11 p., e50.

    Research output: Contribution to journalArticle

  9. Estimating selection pressures on HIV-1 using phylogenetic likelihood models

    Pond, S. L. K., Poon, A. F. Y., Zarate, S., Smith, D. M., Little, S. J., Pillai, S. K., Ellis, R. J., Wong, J. K., Leigh Brown, A., Richman, D. D. & Frost, S. D. W., 2008, In : STATISTICS IN MEDICINE. 27, 23, SI, p. 4779-4789 11 p.

    Research output: Contribution to journalArticle

  10. 2007
  11. Adaptation to human populations is revealed by within-host polymorphisms in HIV-1 and hepatitis C virus

    Poon, A. F. Y., Pond, S. L. K., Bennett, P., Richman, D. D., Leigh Brown, A. J. & Frost, S. D. W., Apr 2007, In : Plos Pathogens. 3, 3

    Research output: Contribution to journalArticle

  12. Evidence of a decline in transmitted HIV-1 drug resistance in the United Kingdom

    Burns, S., Cameron, S., Cane, P., Down, P., Chrystie, I., Churchill, D., Delpech, V., Pillay, D., Dunn, D., Fearnhill, E., Green, H., Porter, K., Easterbrook, P., Zuckerman, M., Geretti, A. M., Gifford, R., Kellam, P., Phillips, A., Sabin, C., Goldberg, D. & 32 others, Gompels, M., Hale, A., Kaye, S., Leigh Brown, A., Orkin, C., Pozniak, A., Robb, G., Smit, E., Tilston, P., Williams, I., Ainsworth, J., Anderson, J., Babiker, A., Fisher, M., Gazzard, B., Gilson, R., Hill, T., Johnson, M., Leen, C., Sadiq, T., Schwenk, A., Walsh, J., Brettle, R., Darbyshire, J., Fidler, S., Hawkins, D., Jaffe, H., Johnson, A., McLean, K., Resistance, UK. C. G. HIV. D., Comm, UK. CHIC. S. & Ste, UK. R. HIV. S., 2007, In : AIDS. 21, 8, p. 1035-1039 5 p.

    Research output: Contribution to journalArticle

  13. HIV phylogenetics: Criminal convictions relying solely on this to establish transmission are unsafe

    Pillay, D., Rambaut, A., Geretti, A. M. & Leigh Brown, A. J., 2007, In : British Medical Journal (BMJ). 335, 7618, p. 460-461 2 p.

    Research output: Contribution to journalArticle

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