Edinburgh Research Explorer

Andrew Leigh-Brown

Professor of Evolutionary Genetics

  1. 2006
  2. Adaptation to Different Human Populations by HIV-1 Revealed by Codon-Based Analyses

    Kosakovsky Pond, S. L., Frost, S. D. W., Grossman, Z., Gravenor, M. B., Richman, D. D. & Leigh Brown, A. J., Jun 2006, In : PLoS Computational Biology. 2, 6, p. 530-538 9 p., e62.

    Research output: Contribution to journalArticle

  3. Bayesian graphical models in the analysis of HIV drug resistance data from the UK HIV Drug Resistance Database

    Lewis, F., Fearnhill, E., Murray, R., Pillay, D., Dunn, D., Leigh Brown, A. & Collaboration, UK. D. R., 2006, In : Antiviral Therapy. 11, 5

    Research output: Contribution to journalArticle

  4. 2005
  5. Phenotypic hypersusceptibility to multiple protease inhibitors and low replicative capacity in patients who are chronically infected with human immunodeficiency virus type 1

    Martinez-Picado, J., Wrin, T., Frost, SDW., Clotet, B., Ruiz, L., Leigh Brown, AJ., Petropoulos, CJ. & Parkin, NT., May 2005, In : Journal of Virology. 79, 10, p. 5907-5913 7 p.

    Research output: Contribution to journalArticle

  6. Human immunodeficiency virus type 1 clade B superinfection: Evidence for differential immune containment of distinct clade B strains

    Yang, OO., Daar, ES., Jamieson, BD., Balamurugan, A., Smith, DM., Pitt, JA., Petropoulos, CJ., Richman, DD., Little, SJ. & Leigh Brown, AJ., Jan 2005, In : Journal of Virology. 79, 2, p. 860-868 9 p.

    Research output: Contribution to journalArticle

  7. Estimating HIV-1 drug resistance in antiretroviral-treated individuals in the United Kingdom

    Pillay, D., Green, H., Matthias, R., Dunn, D., Phillips, A., Sabin, C., Evans, B., Cane, P., Burns, S., Cameron, S., Chrystie, I., Churchill, D., Clarke, J., Easterbrook, P., Zuckerman, M., Goldberg, D., Gompels, M., Hale, T., Robb, G., Leigh Brown, A. & 9 others, Geretti, AM., Kellam, P., Porter, K., Orkin, C., Pozniak, A., Smit, R., Tilston, P., Williams, I. & Res, UK. C. G. HIV. D., 2005, In : The Journal of Infectious Diseases. 192, 6, p. 967-973 7 p.

    Research output: Contribution to journalArticle

  8. Long term probability of detection of HIV-1 drug resistance after starting antiretroviral therapy in routine clinical practice

    Blackham, J., Burns, S., Cameron, S., Cane, P., Chrystie, I., Churchill, D., Clarke, J., Easterbrook, P., Zuckerman, M., Goldberg, D., Gompels, M., Hale, T., Lazarus, L., Leigh Brown, A., Loveday, C., Geretti, AM., Pillay, D., Phillips, A., Sabin, C., Hill, T. & 43 others, Kellam, P., Dunn, D., Porter, K., Green, H., Matthias, R., Pozniak, A., Tilston, P., Williams, I., Babiker, A., Fisher, M., Gilson, R., Johnson, M., Mortimer, J., Peters, B., Scullard, G., Gazzard, B., Bansi, L., Smith, C., Waters, A., Crates, D., Morgan, N., Perry, N., Pullin, A., Harris, W., Bulbeck, S., Mandalia, S., Dodds, J., Fudge, N., Rider, A., Sinka, K., Evans, B., Delpech, V., Larbalestier, N., Gray, K., Youle, M., Lampe, F., Gumley, H., Chaloner, C., Puradiredja, J., Weber, J., Owens, C., Resist, UK. C. G. HIV. D. & Grp, UK. CHIC. S., 2005, In : AIDS. 19, 5, p. 487-494 8 p.

    Research output: Contribution to journalArticle

  9. Using mixtures of amino acids to detect individual- and population-level selection of HIV-1 protease

    Frost, SDW., Pond, SLK., Smith, DM., Richman, DD. & Leigh Brown, AJ., 2005, In : Antiviral Therapy. 10, 4

    Research output: Contribution to journalArticle

  10. 2004
  11. Activation by malaria antigens renders mononuclear cells susceptible to HIV infection and re-activates replication of endogenous HIV in cells from HIV-infected adults

    Froebel, K., Howard, W., Schafer, JR., Howie, F., Whitworth, J., Kaleebu, P., Leigh Brown, AJ. & Riley, E., May 2004, In : Parasite Immunology. 26, 5, p. 213-217 5 p.

    Research output: Contribution to journalArticle

  12. Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection

    Leigh Brown, AJ., Frost, SDW., Good, B., Daar, ES., Simon, V., Markowitz, M., Collier, AC., Connick, E., Conway, B., Margolick, JB., Routy, JP., Corbeil, J., Hellmann, NS., Richman, DD. & Little, SJ., Mar 2004, In : Journal of Virology. 78, 5, p. 2242-2246 5 p.

    Research output: Contribution to journalArticle

  13. 2003
  14. Effects of amino acid and synonymous polymorphisms in HIV-1 protease on viral fitness

    Frost, SDW., Kosakovsky Pond, S., Grossman, Z., Daar, E., Condra, J., Richman, DD., Little, SJ. & Leigh Brown, AJ., Jun 2003, In : Antiviral Therapy. 8, 3

    Research output: Contribution to journalArticle

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