Edinburgh Research Explorer

Andrew Leigh-Brown

Professor of Evolutionary Genetics

  1. 1998
  2. Analysis of human immunodeficiency virus type 1 env and gag sequence variants derived from a mother and two vertically infected children provides evidence for the transmission of multiple sequence variants

    Wade, CM., Lobidel, D. & Leigh Brown, AJ., May 1998, In: Journal of General Virology. 79, 5, p. 1055-1068 14 p.

    Research output: Contribution to journalArticlepeer-review

  3. 1999
  4. Associations between amino acids in the evolution of HIV type 1 protease sequences under indinavir therapy

    Leigh Brown, AJ., Korber, BT. & Condra, JH., 1999, In: Aids research and human retroviruses. 15, 3, p. 247-253 7 p.

    Research output: Contribution to journalArticlepeer-review

  5. Completing the molecular investigation into the HIV outbreak at Glenochil prison

    Yirrell, DL., Hutchinson, SJ., Griffin, M., Gore, SM., Leigh Brown, AJ. & Goldberg, DJ., 1999, In: Epidemiology and Infection. 123, 2, p. 277-282 6 p.

    Research output: Contribution to journalArticlepeer-review

  6. Evolution of envelope sequences of human immunodeficiency virus type 1 in cellular reservoirs in the setting of potent antiviral therapy

    Gunthard, HF., Frost, SDW., Leigh Brown, AJ., Ignacio, CC., Kee, K., Perelson, AS., Spina, CA., Havlir, DV., Hezareh, M., Looney, DJ., Richman, DD. & Wong, JK., 1999, In: Journal of Virology. 73, 11, p. 9404-9412 9 p.

    Research output: Contribution to journalArticlepeer-review

  7. Higher selection pressure from antiretroviral drugs in vivo results in increased evolutionary distance in HIV-1 pol

    Gunthard, HF., Leigh Brown, AJ., D'Aquila, RT., Johnson, VA., Kuritzkes, DR., Richman, DD. & Wong, JK., 1999, In: Virology. 259, 1, p. 154-165 12 p.

    Research output: Contribution to journalArticlepeer-review

  8. Method used to identify previously undiagnosed infections in the HIV outbreak at Glenochil prison

    Hutchinson, SJ., Gore, SM., Goldberg, DJ., Yirrell, DL., McGregor, J., Bird, AG. & Leigh Brown, AJ., 1999, In: Epidemiology and Infection. 123, 2, p. 271-275 5 p.

    Research output: Contribution to journalArticlepeer-review

  9. Sequence clusters in human immunodeficiency virus type 1 reverse transcriptase are associated with subsequent virological response to antiretroviral therapy

    Leigh Brown, AJ., Gunthard, HF., Wong, JK., D'Aquila, RT., Johnson, VA., Kuritzkes, DR. & Richman, DD., 1999, In: The Journal of Infectious Diseases. 180, 4, p. 1043-1049 7 p.

    Research output: Contribution to journalArticlepeer-review

  10. 2000
  11. Molecular evidence for genetic mixing of Arctic and Antarctic subpolar populations of planktonic foraminifers

    Darling, K., Wade, C. M., Stewart, I. A., Kroon, D., Dingle, R. & Leigh Brown, A., 2000, In: Nature. 405, 6782, p. 43-47 5 p.

    Research output: Contribution to journalArticlepeer-review

  12. Multiple sites in HIV-1 reverse transcriptase associated with virological response to combination therapy

    Precious, HM., Gunthard, HF., Wong, JK., D'Aquila, RT., Johnson, VA., Kuritzkes, DR., Richman, DD. & Leigh Brown, AJ., 2000, In: AIDS. 14, 1, p. 31-36 6 p.

    Research output: Contribution to journalArticlepeer-review

  13. Transmission and fitness of drug resistant strains of HIV

    Leigh Brown, AJ., Frost, SDW., Whitcomb, JM., McLean, AR., Hellmann, NS., Leen, CS., Brettle, RP., Havlir, DV., Mathews, WC., Richman, DD. & Little, SJ., 2000, In: AIDS. 14, 4

    Research output: Contribution to journalArticlepeer-review

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