Edinburgh Research Explorer

Prof Andrew Leigh-Brown

Professor of Evolutionary Genetics

  1. 2001
  2. Evidence for positive selection driving the evolution of HIV-1 env under potent antiviral therapy

    Frost, SDW., Gunthard, HF., Wong, JK., Havlir, D., Richman, DD. & Leigh Brown, AJ., 2001, In : Virology. 284, 2, p. 250-258 9 p.

    Research output: Contribution to journalArticle

  3. Genetic drift and within-host metapopulation dynamics of HIV-1 infection

    Frost, SDW., Dumaurier, MJ., Wain-Hobson, S. & Leigh Brown, AJ., 2001, In : Proceedings of the National Academy of Sciences. 98, 12, p. 6975-6980 6 p.

    Research output: Contribution to journalArticle

  4. Mismatched human leukocyte antigen alleles protect against heterosexual HIV transmission

    Lockett, SF., Robertson, JR., Brettle, RP., Yap, PL., Middleton, D. & Leigh Brown, AJ., 2001, In : Journal of Acquired Immune Deficiency Syndromes. 27, 3, p. 277-280 4 p.

    Research output: Contribution to journalArticle

  5. Residual human immunodeficiency virus (HIV) type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal fluid after suppression of viremia for 2 years

    Gunthard, HF., Havlir, DV., Fiscus, S., Zhang, ZQ., Eron, J., Mellors, J., Gulick, R., Frost, SDW., Leigh Brown, AJ., Schleif, W., Valentine, F., Jonas, L., Meibohm, A., Ignacio, CC., Isaacs, R., Gamagami, R., Emini, E., Haase, A., Richman, DD. & Wong, JK., 2001, In : The Journal of Infectious Diseases. 183, 9, p. 1318-1327 10 p.

    Research output: Contribution to journalArticle

  6. Soluble recombinant HTLV-1 surface glycoprotein competitively inhibits syncytia formation and viral infection of cells

    Jassal, SR., Lairmore, MD., Leigh Brown, AJ. & Brighty, DW., 2001, In : Virus Research. 78, 1-2, p. 17-34 18 p.

    Research output: Contribution to journalArticle

  7. 2000
  8. Evolution of lamivudine resistance in human immunodeficiency virus type 1-infected individuals: the relative roles of drift and selection

    Frost, SDW., Nijhuis, M., Schuurman, R., Boucher, CAB. & Leigh Brown, AJ., Jul 2000, In : Journal of Virology. 74, 14, p. 6262-6268 7 p.

    Research output: Contribution to journalArticle

  9. Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine

    Hanna, GJ., Johnson, VA., Kuritzkes, DR., Richman, DD., Leigh Brown, AJ., Savara, AV., Hazelwood, JD. & D'Aquila, RT., Mar 2000, In : The Journal of Infectious Diseases. 181, 3, p. 904-911 8 p.

    Research output: Contribution to journalArticle

  10. Molecular evidence for genetic mixing of Arctic and Antarctic subpolar populations of planktonic foraminifers

    Darling, K., Wade, C. M., Stewart, I. A., Kroon, D., Dingle, R. & Leigh Brown, A., 2000, In : Nature. 405, 6782, p. 43-47 5 p.

    Research output: Contribution to journalArticle

  11. Multiple sites in HIV-1 reverse transcriptase associated with virological response to combination therapy

    Precious, HM., Gunthard, HF., Wong, JK., D'Aquila, RT., Johnson, VA., Kuritzkes, DR., Richman, DD. & Leigh Brown, AJ., 2000, In : AIDS. 14, 1, p. 31-36 6 p.

    Research output: Contribution to journalArticle

  12. Transmission and fitness of drug resistant strains of HIV

    Leigh Brown, AJ., Frost, SDW., Whitcomb, JM., McLean, AR., Hellmann, NS., Leen, CS., Brettle, RP., Havlir, DV., Mathews, WC., Richman, DD. & Little, SJ., 2000, In : AIDS. 14, 4

    Research output: Contribution to journalArticle

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