Edinburgh Research Explorer

Prof Andrew Leigh-Brown

Professor of Evolutionary Genetics

  1. 2002
  2. Human macrophages accumulate HIV-1 particles in MHC II compartments

    Raposo, G., Moore, M., Innes, D., Leijendekker, R., Leigh Brown, A., Benaroch, P. & Geuze, H., 2002, In : Traffic. 3, 10, p. 718-729 12 p.

    Research output: Contribution to journalArticle

  3. Viral dynamics during structured treatment interruptions of chronic human immunodeficiency virus type 1 infection

    Frost, SDW., Martinez-Picado, J., Ruiz, L., Clotet, B. & Leigh Brown, AJ., Feb 2002, In : Journal of Virology. 76, 3, p. 968-979 12 p.

    Research output: Contribution to journalArticle

  4. Association of antiretroviral resistance genotypes with response to therapy--comparison of three models

    Nicol, M., Frost, SDW., McDonagh, S., Burns, SM., Clutterbuck, D., McMillan, A., Leen, CS. & Leigh Brown, AJ., Oct 2002, In : Antiviral Therapy. 7, 3, p. 151-157 7 p.

    Research output: Contribution to journalArticle

  5. 2003
  6. Changing transmission fitness of drug-resistant human immunodeficiency virus against a background of evolving antiretroviral therapy - Reply

    Leigh Brown, AJ., Frost, SDW., Mathews, WC., Dawson, K., Hellmann, NS., Daar, ES., Richman, DD. & Little, SJ., 2003, In : The Journal of Infectious Diseases. 188, 8, p. 1258-1259 2 p.

    Research output: Contribution to journalArticle

  7. Clade BHIV-1 superinfection with wild-type virus after primary infection with drug-resistant clade B virus

    Koelsch, KK., Smith, DM., Little, SJ., Ignacio, CC., Macaranas, TR., Leigh Brown, AJ., Petropoulos, CJ., Richman, DD. & Wong, JK., 2003, In : AIDS. 17, 7, p. F11-F16

    Research output: Contribution to journalArticle

  8. Differences in HIV-1 pol sequences from female genital tract and blood during antiretroviral therapy

    De Pasquale, MP., Leigh Brown, AJ., Uvin, SC., Allega-Ingersoll, J., Caliendo, AM., Sutton, L., Donahue, S. & D'Aquila, RT., 2003, In : Journal of Acquired Immune Deficiency Syndromes. 34, 1, p. 37-44 8 p.

    Research output: Contribution to journalArticle

  9. Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: Intrinsic stability predicts lifelong persistence

    Strain, MC., Gunthard, HF., Havlir, DV., Ignacio, CC., Smith, DM., Leigh Brown, AJ., Macaranas, TR., Lam, RY., Daly, OA., Fischer, M., Opravil, M., Levine, H., Bacheler, L., Spina, CA., Richman, DD. & Wong, JK., 2003, In : Proceedings of the National Academy of Sciences. 100, 8, p. 4819-4824 6 p.

    Research output: Contribution to journalArticle

  10. Transmission fitness of drug-resistant human immunodeficiency virus and the prevalence of resistance in the antiretroviral-treated population

    Leigh Brown, AJ., Frost, SDW., Mathews, WC., Dawson, K., Hellmann, NS., Daar, ES., Richman, DD. & Little, SJ., 2003, In : The Journal of Infectious Diseases. 187, 4, p. 683-686 4 p.

    Research output: Contribution to journalArticle

  11. Effects of amino acid and synonymous polymorphisms in HIV-1 protease on viral fitness

    Frost, SDW., Kosakovsky Pond, S., Grossman, Z., Daar, E., Condra, J., Richman, DD., Little, SJ. & Leigh Brown, AJ., Jun 2003, In : Antiviral Therapy. 8, 3

    Research output: Contribution to journalArticle

  12. 2004
  13. Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection

    Leigh Brown, AJ., Frost, SDW., Good, B., Daar, ES., Simon, V., Markowitz, M., Collier, AC., Connick, E., Conway, B., Margolick, JB., Routy, JP., Corbeil, J., Hellmann, NS., Richman, DD. & Little, SJ., Mar 2004, In : Journal of Virology. 78, 5, p. 2242-2246 5 p.

    Research output: Contribution to journalArticle

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