Edinburgh Research Explorer

Prof Andrew Leigh-Brown

Professor of Evolutionary Genetics

  1. 2020
  2. Pervasive and non-random recombination in near full-length HIV genomes from Uganda

    Grant, H., Hodcroft, E., Ssemwanga, D., Kitayimbwa, J., Yebra, G., Esquivel Gomez, L. R., Frampton, D., Gall, A., Kellam, P., de Oliveira, T., Bbosa, N., Nsubuga, R. N., Kibengo, F., Kwan, T. H., Lycett, S., Kao, R., Robertson, D., Ratmann, O., Fraser, C., Pillay, D. & 2 others, Kaleebu, P. & Leigh-Brown, A., 2 Jan 2020, (Accepted/In press) In : Virus Evolution.

    Research output: Contribution to journalArticle

  3. 2019
  4. Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis

    Ratmann, O., Grabowski, M. K., Hall, M., Golubchik, T., Wymant, C., Abeler-Dörner, L., Bonsall, D., Hoppe, A., Brown, A. L., de Oliveira, T., Gall, A., Kellam, P., Pillay, D., Kagaayi, J., Kigozi, G., Quinn, T. C., Wawer, M. J., Laeyendecker, O., Serwadda, D., Gray, R. H. & 1 others, Fraser, C., 29 Mar 2019, In : Nature Communications. 10, 1411.

    Research output: Contribution to journalArticle

  5. Phylogeography of HIV-1 suggests that Ugandan fishing communities are a sink for, not a source of, virus from general populations

    Bbosa, N., Ssemwanga, D., Nsubuga, R. N., Salazar-Gonzalez, J. F., Salazar, M. G., Nanyonjo, M., Kuteesa, M., Seeley, J., Kiwanuka, N., Bagaya, B. S., Yebra, G., Leigh-Brown, A. & Kaleebu, P., 31 Jan 2019, In : Scientific Reports. 9, 1, 8 p., 1051.

    Research output: Contribution to journalArticle

  6. HIV-1 DNA is Maintained in Antigen-Specific CD4+ T Cell Subsets in Patients on Long-Term Antiretroviral Therapy Regardless of Recurrent Antigen Exposure

    Hey-Nguyen, W., Bailey, M., Xu, Y., Suzuki, K., van Bockel, D., Finlayson, R., Leigh Brown, A., Carr, A., Cooper, D. A., Kelleher, A. D., Koelsch, K. K. & Zaunders, J., 11 Jan 2019, In : Aids research and human retroviruses. 35, 1, p. 112-120 9 p.

    Research output: Contribution to journalArticle

  7. 2018
  8. Non-disclosed men who have sex with men in UK HIV transmission networks: phylogenetic analysis of surveillance data

    Ragonnet-Cronin, M., Hué, S., Hodcroft, E. B., Tostevin, A., Dunn, D., Fawcett, T., Pozniak, A., Brown, A. E., Delpech, V. & Leigh-Brown, A., 1 Jun 2018, In : Lancet HIV. 5, 6, p. e309–e316

    Research output: Contribution to journalArticle

  9. Recent and rapid transmission of HIV among people who inject drugs in Scotland revealed through phylogenetic analysis

    Ragonnet-Cronin, M., Jackson, C., Bradley-Stewart, A., Aitken, C., McAuley, A., Palmateer, N., Gunson, R., Goldberg, D. J., Milosevic, C. & Leigh Brown, A. J., 10 Apr 2018, In : The Journal of Infectious Diseases. 217, 12, p. 1875-1882 8 p.

    Research output: Contribution to journalArticle

  10. A high HIV-1 strain variability in London, UK, revealed by full-genome analysis: Results from the ICONIC project

    Yebra, G., Frampton, D., Gallo Cassarino, T., Raffle, J., Hubb, J., Ferns, R. B., Waters, L., Tong, C. Y. W., Kozlakidis, Z., Hayward, A., Kellam, P., Pillay, D., Clark, D. A., Nastouli, E., Leigh Brown, A. J. & ICONIC Consortium, 1 Feb 2018, In : PLoS ONE. 13, 2, p. e0192081

    Research output: Contribution to journalArticle

  11. HIV-TRACE (Transmission Cluster Engine): a tool for large scale molecular epidemiology of HIV-1 and other rapidly evolving pathogens

    Kosakovsky Pond, S. L., Weaver, S., Leigh Brown, A. J. & Wertheim, J. O., 31 Jan 2018, In : Molecular Biology and Evolution. 16 p., msy016.

    Research output: Contribution to journalArticle

  12. 2017
  13. Recent trends and patterns in HIV-1 transmitted drug resistance in the United Kingdom

    Tostevin, A., White, E., Dunn, D., Croxford, S., Delpech, V., Williams, I., Asboe, D., Pozniak, A., Churchill, D., Geretti, A., Pillay, D., Sabin, C., Leigh-Brown, A. & Smit, E., Mar 2017, In : HIV Medicine.

    Research output: Contribution to journalArticle

  14. Quantifying predictors for the spatial diffusion of avian influenza virus in China

    Lu, L., Leigh-Brown, A. & Lycett, S., 13 Jan 2017, In : BMC Evolutionary Biology. 17, 1, 16.

    Research output: Contribution to journalArticle

  15. Phylogenetic Tools for Generalized HIV-1 Epidemics: Findings from the PANGEA-HIV Methods Comparison

    Ratmann, O., Hodcroft, E., Pickles, M., Cori, A., Hall, M., Lycett, S., Colijn, C., Leigh Brown, A. & Fraser, C., Jan 2017, In : Molecular Biology and Evolution. 34, 10, p. 185-203 31 p.

    Research output: Contribution to journalArticle

  16. 2016
  17. Reconstructing the HIV-1 CRF02_AG and CRF06_cpx Epidemics in Burkina Faso and West Africa using early samples

    Yebra, G., Kalish, M. L. & Leigh Brown, A. J., Dec 2016, In : Infection, Genetics and Evolution. 46, p. 209-218 10 p.

    Research output: Contribution to journalArticle

  18. A Direct Comparison of Two Densely Sampled HIV Epidemics: The UK and Switzerland

    Ragonnet-Cronin, M. L., Shilaih, M., Günthard, H. F., Hodcroft, E. B., Böni, J., Fearnhill, E., Dunn, D., Yerly, S., Klimkait, T., Aubert, V., Yang, W-L., Brown, A. E., Lycett, S. J., Kouyos, R. & Leigh Brown, A., 19 Sep 2016, In : Scientific Reports. 6, 32251.

    Research output: Contribution to journalArticle

  19. 2015
  20. Transmission of non-B HIV subtypes in the UK is increasingly driven by large non-heterosexual clusters

    Ragonnet-Cronin, M., Lycett, S., Hodcroft, E., Hué, S., Fearnhill, E., Brown, A. E., Delpech, V., Dunn, D., Leigh Brown, A. J. & UK HIV Drug Resistance Database, 23 Dec 2015, In : The Journal of Infectious Diseases. 213, 9, p. 1410-1418

    Research output: Contribution to journalArticle

  21. Analysis of the History and Spread of HIV-1 in Uganda using phylodynamics

    Yebra, G., Ragonnet-Cronin, M., Ssemwanga, D., Parry, C. M., Logue, C. H., Cane, P. A., Kaleebu, P. & Leigh-Brown, A. J., 1 Jul 2015, In : Journal of General Virology. 96, p. 1890–1898

    Research output: Contribution to journalArticle

  22. PANGEA-HIV: phylogenetics for generalised epidemics in Africa

    Pillay, D., Herbeck, J., Cohen, M. S., de Oliveira, T., Fraser, C., Ratmann, O., Brown, A. L., Kellam, P. & PANGEA-HIV Consortium, Mar 2015, In : The Lancet Infectious Diseases. 15, 3, p. 259-61 3 p.

    Research output: Contribution to journalComment/debate

  23. 2014
  24. Phylogenetic studies of transmission dynamics in generalized HIV epidemics: An essential tool where the burden is greatest?

    Dennis, A. M., Herbeck, J. T., Leigh Brown, A., Kellam, P., de Oliveira, T., Pillay, D., Fraser, C. & Cohen, M. S., 1 Oct 2014, In : Journal of Acquired Immune Deficiency Syndromes. 67, 2, p. 181-95 15 p.

    Research output: Contribution to journalArticle

  25. Determining the Phylogenetic and Phylogeographic Origin of Highly Pathogenic Avian Influenza (H7N3) in Mexico

    Lu, L., Lycett, S. J. & Leigh Brown, A. J., 16 Sep 2014, In : PLoS ONE. 9, 9, 13 p., e107330.

    Research output: Contribution to journalArticle

  26. Intercontinental dispersal of HIV-1 subtype B associated with transmission among men who have sex with men in Japan

    Takebe, Y., Naito, Y., Raghwani, J., Fearnhill, E., Sano, T., Kusagawa, S., Mbisa, J. L., Zhang, H., Matano, T., Leigh-Brown, A., Pybus, O. G., Dunn, D., Kondo, M. & UK Collaborative Group on HIV Drug Resistance, 1 Sep 2014, In : Journal of Virology. 88, 17, p. 9864-76 13 p.

    Research output: Contribution to journalArticle

  27. Phylogenetic analyses reveal HIV-1 infections between men misclassified as heterosexual transmissions

    Hué, S., Brown, A. E., Ragonnet-Cronin, M., Lycett, S. J., Dunn, D. T., Fearnhill, E., Dolling, D. I., Pozniak, A., Pillay, D., Delpech, V. C. & Leigh Brown, A. J., 24 Aug 2014, In : AIDS. 28, 13, p. 1967-75 9 p.

    Research output: Contribution to journalArticle

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