Edinburgh Research Explorer

Prof Andrew McIntosh

Chair of Biological Psychiatry

Profile photo

Willingness to take PhD students: Yes

PhD Projects

1. Identifying genetic and environmental risk factors for depression

2. Identifying the heterogeneity underlying depressive illnesses

3. Studying the longitudinal changes before and after the onset of depression

4. Identifying the mechanisms of psychological resilience

Education/Academic qualification

Master of Science, Edinburgh Napier University
Applied Statistics
Doctor of Medicine, University of Edinburgh
Commonalities and differences between schizophrenia and bipolar disorder
Master of Philosophy (MPhil), University of Edinburgh
Anatomy of the functional psychoses
Bachelor of Medicine and Bachelor of Surgery, University of Aberdeen
Bachelor of Science, University of Aberdeen
Close coupling of mRNA synthesis to amino acid metabolism

Professional Qualifications

1999Member of The Royal College of Psychiatrists, MRCPsych
2012Fellow of the Royal College of Psychiatrists, FRCPsych

Biography

Andrew McIntosh is Professor of Biological Psychiatry and a Senior Clinical Research Fellow at the University of Edinburgh. He trained in Medicine at the University of Aberdeen before completing further postgraduate training in Edinburgh in Psychiatry and in Applied Statistics. He leads the Generation Scotland Expert Working Group for Psychiatric Disorders and is involved in several genetic consortia, including ENIGMA and the Psychiatric Genomics Consortium.

My research in a nutshell

Professor McIntosh’s aims to better understand the causes and consequences of depression and then use that knowledge to address the unmet needs of the individuals and families affected by the disorder. He currently works with large population-based studies of depression, such as Generation Scotland and UK Biobank, that have information on depression alongside genetic information, data from the electronic medical record and other detailed measurements of physical and mental health.

Research Interests

  • Depression and psychological resilience
  • The genetic and environmental causes of depression
  • The mechanisms and causal consequences of depression 
  • Public enagagement around the use of mental health data in research

Highlighted research outputs

  1. Uncovering the genetic architecture of major depression

    Research output: Contribution to journalReview article

  2. Epigenetic signatures of starting and stopping smoking

    Research output: Contribution to journalArticle

  3. How data science can advance mental health research

    Research output: Contribution to journalArticle

  4. Genetic and environmental contributions to psychological resilience and coping

    Research output: Contribution to journalArticle

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Highlighted research activities & awards

  1. Song writing workshop for harmony choir

    Activity: Participating in or organising an event typesPublic Engagement – Public lecture/debate/seminar

  2. Resilience Ceilidh on mental health

    Activity: Participating in or organising an event typesPublic Engagement – Festival/Exhibition

  3. Mental Health in STEM Panel

    Activity: Participating in or organising an event typesPublic Engagement – Public lecture/debate/seminar

  4. Scottish Parliament

    Activity: Visiting an external institution typesResearch and Teaching at External Organisation

  5. Celebration of Scottish Health Research Cohorts

    Activity: Participating in or organising an event typesPublic Engagement – Public lecture/debate/seminar

  6. Wellcome Trust (External organisation)

    Activity: Membership typesMembership of peer review panel or committee

  7. Co-chair of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

    Activity: Consultancy typesContribution to the work of national or international committees and working groups

  8. Mental Health Week

    Activity: Participating in or organising an event typesPublic Engagement – Public lecture/debate/seminar

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