Edinburgh Research Explorer

Prof Andrew McIntosh

Chair of Biological Psychiatry

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Professor Andrew McIntosh
School of Clinical Sciences: Division of Psychiatry

Centre for Clinical Brain Sciences

Centre for Genomic and Experimental Medicine

Centre for Cognitive Ageing and Cognitive Epidemiology

Biography

Andrew McIntosh is Professor of Biological Psychiatry and a Senior Clinical Research Fellow at the University of Edinburgh. He trained in Medicine at the University of Aberdeen before completing further postgraduate training in Edinburgh in Psychiatry and in Applied Statistics. He leads the Generation Scotland Expert Working Group for Psychiatric Disorders and is involved in several genetic consortia, including ENIGMA and the Psychiatric Genomics Consortium.

Master of Science, Edinburgh Napier University

Doctor of Medicine, University of Edinburgh

Master of Philosophy (MPhil), University of Edinburgh

Bachelor of Medicine and Bachelor of Surgery, University of Aberdeen

Bachelor of Science, University of Aberdeen

19992012 Member of The Royal College of Psychiatrists, MRCPsych
2012 → … Fellow of the Royal College of Psychiatrists, FRCPsych

Employment

Chair of Biological Psychiatry

Deanery of Clinical Sciences

University of Edinburgh

United Kingdom

1 Aug 2012 → present

Chair of Biological Psychiatry

Deanery of Molecular, Genetic and Population Health Sciences

University of Edinburgh

United Kingdom

1 Nov 19997 Aug 2012

Centre for Clinical Brain Sciences

University of Edinburgh

1 Aug 2012 → present

Edinburgh Neuroscience

University of Edinburgh

1 Sep 2015 → present

Edinburgh Imaging

University of Edinburgh

Edinburgh, United Kingdom

29 Oct 2010 → present

Research output

Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition

23andMe Research Team, 2 Oct 2019, In : Psychological Medicine . p. 1-10 10 p.

Impact of polygenic risk for Schizophrenia on cortical structure in UK Biobank

Neilson, E., Shen, X., Cox, S. R., Clarke, T., Wigmore, E. M., Gibson, J., Howard, D. M., Adams, M. J., Harris, M. A., Davies, G., Deary, I. J., Whalley, H. C., Mcintosh, A. M. & Lawrie, S. M., Oct 2019, In : Biological Psychiatry. 86, 7, p. 536-544

Correction: Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals

ENIGMA Bipolar Disorder Working Group, 16 Sep 2019, In : Neuropsychopharmacology.

Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte–myelin dysfunction

Vasistha, N. A., Johnstone, M., Barton, S. K., Mayerl, S. E., Thangaraj Selvaraj, B., Thomson, P. A., Dando, O., Grünewald, E., Alloza, C., Bastin, M. E., Livesey, M. R., Economides, K., Magnani, D., Makedonopolou, P., Burr, K., Story, D. J., Blackwood, D. H. R., Wyllie, D. J. A., Mcintosh, A. M., Millar, J. K. & 4 othersFfrench-constant, C., Hardingham, G. E., Lawrie, S. M. & Chandran, S., 3 Sep 2019, In : Molecular Psychiatry.

White matter disturbances in major depressive disorder: a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group

Van Velzen, L. S., Kelly, S., Isaev, D., Aleman, A., Aftanas, L. I., Bauer, J., Baune, B. T., Brak, I. V., Carballedo, A., Connolly, C. G., Couvy-duchesne, B., Cullen, K. R., Danilenko, K. V., Dannlowski, U., Enneking, V., Filimonova, E., Förster, K., Frodl, T., Gotlib, I. H., Groenewold, N. A. & 51 othersGrotegerd, D., Harris, M. A., Hatton, S. N., Hawkins, E. L., Hickie, I. B., Ho, T. C., Jansen, A., Kircher, T., Klimes-dougan, B., Kochunov, P., Krug, A., Lagopoulos, J., Lee, R., Lett, T. A., Li, M., Macmaster, F. P., Martin, N. G., Mcintosh, A. M., Mclellan, Q., Meinert, S., Nenadić, I., Osipov, E., Penninx, B. W. J. H., Portella, M. J., Repple, J., Roos, A., Sacchet, M. D., Sämann, P. G., Schnell, K., Shen, X., Sim, K., Stein, D. J., Van Tol, M., Tomyshev, A. S., Tozzi, L., Veer, I. M., Vermeiren, R., Vives-gilabert, Y., Walter, H., Walter, M., Van Der Wee, N. J. A., Van Der Werff, S. J. A., Schreiner, M. W., Whalley, H. C., Wright, M. J., Yang, T. T., Zhu, A., Veltman, D. J., Thompson, P. M., Jahanshad, N. & Schmaal, L., 30 Aug 2019, In : Molecular Psychiatry.

Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., He, J., Fan, D., Fowdar, J., Kennedy, M., Pitcher, T., Pearson, J., Halliday, G., Kwok, J. B., Hickie, I., Lewis, S., Anderson, T., Silburn, P. A., Mellick, G. D., Harris, S. E. & 13 othersRedmond, P., Murray, A. D., Porteous, D. J., Haley, C. S., Evans, K. L., Mcintosh, A. M., Yang, J., Gratten, J., Marioni, R. E., Wray, N. R., Deary, I. J., Mcrae, A. F. & Visscher, P. M., 23 Aug 2019, In : Genome Medicine. 11, 1, 54.

Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals

ENIGMA Bipolar Disorder Working Group, Vieta, E., Wessa, M., Whalley, H., Zanetti, M. V., Leboyer, M., Mangin, J-F., Henry, C., Duchesnay, E. & Houenou, J., 21 Aug 2019, In : Neuropsychopharmacology.

Indicators of Mental Disorders in UK Biobank – A comparison of approaches

Davis, K., Adams, M. J., Breen, G., Coleman, J. R., Dregan, A., Gaspar, H., Hubel, C., Lee, W., McIntosh, A., Nolan, J., Pearsall, R. & Hotopf, M., 8 Aug 2019, In : International Journal of Methods in Psychiatric Research.

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 5 Aug 2019, In : Biological Psychiatry.

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

Evangelou, E., Gao, H., Chu, C., Ntritsos, G., Blakeley, P., Butts, A. R., Pazoki, R., Suzuki, H., Koskeridis, F., Yiorkas, A. M., Karaman, I., Elliott, J., Luo, Q., Aeschbacher, S., Bartz, T. M., Baumeister, S. E., Braund, P. S., Brown, M. R., Brody, J. A., Clarke, T-K. & 78 othersDimou, N., Faul, J. D., Homuth, G., Jackson, A. U., Kentistou, K. A., Joshi, P. K., Lemaitre, R. N., Lind, P. A., Lyytikäinen, L-P., Mangino, M., Milaneschi, Y., Nelson, C. P., Nolte, I. M., Perälä, M-M., Polasek, O., Porteous, D., Ratliff, S. M., Smith, J. A., Stančáková, A., Teumer, A., Tuominen, S., Thériault, S., Vangipurapu, J., Whitfield, J. B., Wood, A., Yao, J., Yu, B., Zhao, W., Arking, D. E., Auvinen, J., Liu, C., Männikkö, M., Risch, L., Rotter, J. I., Snieder, H., Veijola, J., Blakemore, A. I., Boehnke, M., Campbell, H., Conen, D., Eriksson, J. G., Grabe, H. J., Guo, X., van der Harst, P., Hartman, C. A., Hayward, C., Heath, A. C., Jarvelin, M-R., Kähönen, M., Kardia, S. L. R., Kühne, M., Kuusisto, J., Laakso, M., Lahti, J., Lehtimäki, T., McIntosh, A. M., Mohlke, K. L., Morrison, A. C., Martin, N. G., Oldehinkel, A. J., Penninx, B. W. J. H., Psaty, B. M., Raitakari, O. T., Rudan, I., Samani, N. J., Scott, L. J., Spector, T. D., Verweij, N., Weir, D. R., Wilson, J. F., Levy, D., Tzoulaki, I., Bell, J. D., Matthews, P. M., Rothenfluh, A., Desrivières, S., Schumann, G. & Elliott, P., 29 Jul 2019, In : Nature Human Behaviour.

No Alterations of Brain Structural Asymmetry in Major Depressive Disorder: An ENIGMA Consortium Analysis

De Kovel, C. G. F., Aftanas, L., Aleman, A., Alexander-bloch, A. F., Baune, B. T., Brack, I., Bülow, R., Busatto Filho, G., Carballedo, A., Connolly, C. G., Cullen, K. R., Dannlowski, U., Davey, C. G., Dima, D., Dohm, K., Erwin-grabner, T., Frodl, T., Fu, C. H. Y., Hall, G. B., Glahn, D. C. & 58 othersGodlewska, B., Gotlib, I. H., Goya-maldonado, R., Grabe, H. J., Groenewold, N. A., Grotegerd, D., Gruber, O., Harris, M. A., Harrison, B. J., Hatton, S. N., Hickie, I. B., Ho, T. C., Jahanshad, N., Kircher, T., Krämer, B., Krug, A., Lagopoulos, J., Leehr, E. J., Li, M., Macmaster, F. P., Macqueen, G., Mcintosh, A. M., Mclellan, Q., Medland, S. E., Mueller, B. A., Nenadic, I., Osipov, E., Papmeyer, M., Portella, M. J., Reneman, L., Rosa, P. G. P., Sacchet, M. D., Schnell, K., Schrantee, A., Sim, K., Simulionyte, E., Sindermann, L., Singh, A., Stein, D. J., Ubani, B. N., Van Der Wee, N. J. A., Van Der Werff, S. J. A., Veer, I. M., Vives-gilabert, Y., Völzke, H., Walter, H., Walter, M., Schreiner, M. W., Whalley, H., Winter, N., Wittfeld, K., Yang, T. T., Yüksel, D., Zaremba, D., Thompson, P. M., Veltman, D. J., Schmaal, L. & Francks, C., 29 Jul 2019, In : American Journal of Psychiatry. p. appi.ajp.2019.1

Stratifying major depressive disorder by polygenic risk for schizophrenia in relation to structural brain measures

Harris, M. A., Shen, X., Cox, S., Gibson, J., Adams, M. J., Clarke, T-K., Deary, I., Lawrie, S., McIntosh, A. & Whalley, H., 18 Jul 2019, In : Psychological Medicine .

Factors associated with sharing e-mail information and mental health survey participation in large population cohorts

Adams, M. J., Hill, W. D., Howard, D. M., Dashti, H. S., Davis, K. A. S., Campbell, A., Clarke, T., Deary, I. J., Hayward, C., Porteous, D., Hotopf, M. & Mcintosh, A. M., 1 Jul 2019, In : International Journal of Epidemiology.

White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-late life

Shen, X., Adams, M. J., Ritakari, T., Cox, S., McIntosh, A. & Whalley, H., 21 Jun 2019, In : Biological Psychiatry.

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

Czamara, D., Eraslan, G., Page, C. M., Lahti, J., Lahti-Pulkkinen, M., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Nystad, W., Håberg, S. E., London, S. J., O’Donnell, K. J., Garg, E., Meaney, M. J., Entringer, S., Wadhwa, P. D., Buss, C., Jones, M. J. & 210 othersLin, D. T. S., MacIsaac, J. L., Kobor, M. S., Koen, N., Zar, H. J., Koenen, K. C., Dalvie, S., Stein, D. J., Kondofersky, I., Müller, N. S., Theis, F. J., Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. F. M., Bacanu, S-A., Bækvad-Hansen, M., Beekman, A. T. F., Bigdeli, T. B., Blackwood, D. H. R., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J., Cai, N., Castelao, E., Christensen, J. H., Clarke, T-K., Coleman, J. R. I., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Dolan, C. V., Dunn, E. C., Eley, T. C., Escott-Price, V., Kiadeh, F. F. H., Finucane, H. K., Forstner, A. J., Frank, J., Gaspar, H. A., Gill, M., Goes, F. S., Gordon, S. D., Grove, J., Hall, L. S., Hansen, C. S., Hansen, T. F., Herms, S., Hickie, I. B., Hoffmann, P., Homuth, G., Horn, C., Hottenga, J-J., Hougaard, D. M., Ising, M., Jansen, R., Jorgenson, E., Knowles, J. A., Kohane, I. S., Kraft, J., Kretzschmar, W. W., Krogh, J., Kutalik, Z., Li, Y., Lind, P. A., MacIntyre, D. J., MacKinnon, D. F., Maier, R. M., Maier, W., Marchini, J., Mbarek, H., McGrath, P., McGuffin, P., Medland, S. E., Mehta, D., Middeldorp, C. M., Mihailov, E., Milaneschi, Y., Milani, L., Mondimore, F. M., Montgomery, G. W., Mostafavi, S., Mullins, N., Nauck, M., Ng, B., Nivard, M. G., Nyholt, D. R., O’Reilly, P. F., Oskarsson, H., Owen, M. J., Painter, J. N., Pedersen, C. B., Pedersen, M. G., Peterson, R. E., Pettersson, E., Peyrot, W. J., Pistis, G., Posthuma, D., Quiroz, J. A., Qvist, P., Rice, J. P., Riley, B. P., Rivera, M., Mirza, S. S., Schoevers, R., Schulte, E. C., Shen, L., Shi, J., Shyn, S. I., Sigurdsson, E., Sinnamon, G. C. B., Smit, J. H., Smith, D. J., Stefansson, H., Steinberg, S., Streit, F., Strohmaier, J., Tansey, K. E., Teismann, H., Teumer, A., Thompson, W., Thomson, P. A., Thorgeirsson, T. E., Traylor, M., Treutlein, J., Trubetskoy, V., Uitterlinden, A. G., Umbricht, D., Van der Auwera, S., van Hemert, A. M., Viktorin, A., Visscher, P. M., Wang, Y., Webb, B. T., Weinsheimer, S. M., Wellmann, J., Willemsen, G., Witt, S. H., Wu, Y., Xi, H. S., Yang, J., Zhang, F., Arolt, V., Baune, B. T., Berger, K., Boomsma, D. I., Cichon, S., Dannlowski, U., de Geus, E. J. C., DePaulo, J. R., Domenici, E., Domschke, K., Esko, T., Grabe, H. J., Hamilton, S. P., Hayward, C., Heath, A. C., Kendler, K. S., Kloiber, S., Lewis, G., Li, Q. S., Lucae, S., Madden, P. A. F., Magnusson, P. K., Martin, N. G., McIntosh, A. M., Metspalu, A., Mors, O., Mortensen, P. B., Müller-Myhsok, B., Nordentoft, M., Nöthen, M. M., O’Donovan, M. C., Paciga, S. A., Pedersen, N. L., Penninx, B. W. J. H., Perlis, R. H., Porteous, D. J., Potash, J. B., Preisig, M., Rietschel, M., Schaefer, C., Schulze, T. G., Smoller, J. W., Stefansson, K., Tiemeier, H., Uher, R., Völzke, H., Weissman, M. M., Werge, T., Lewis, C. M., Levinson, D. F., Breen, G., Børglum, A. D., Sullivan, P. F., Räikkönen, K., Binder, E. B. & Consortium, M. D. D. W. G. O. T. P. G., 11 Jun 2019, In : Nature Communications. 10, 1, 2548 .

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

Bermingham, M., Walker, R., Marioni, R., Morris, S., Rawlik, K., Zeng, Y., Campbell, A., Redmond, P., Whalley, H., Adams, M. J., Hayward, C., Deary, I., Porteous, D., McIntosh, A. & Evans, K., 4 Jun 2019, In : EBioMedicine. 43, p. 576-586

Genome-wide association study of multisite chronic pain in UK biobank

Johnston, K. J. A., Adams, M. J., Nicholl, B. I., Ward, J., Strawbridge, R. J., Ferguson, A., McIntosh, A. M., Bailey, M. E. S. & Smith, D. J., 1 Jun 2019, In : PLoS Genetics. 15, 6, e1008164.

Insulin resistance: Genetic associations with depression and cognition in population based cohorts

Frangou, S., Shirali, M., Adams, M. J., Howard, D. M., Gibson, J., Hall, L. S., Smith, B. H., Padmanabhan, S., Murray, A. D., Porteous, D. J., Haley, C. S., Deary, I. J., Clarke, T. & Mcintosh, A. M., Jun 2019, In : Experimental neurology. 316, p. 20-26

The role of neuroticism in self-harm and suicidal ideation: Results from two UK population-based cohorts

Hafferty, J. D., Navrady, L. B., Adams, M. J., Howard, D. M., Campbell, A. I., Whalley, H. C., Lawrie, S. M., Nicodemus, K. K., Porteous, D. J., Deary, I. J. & Mcintosh, A. M., 23 May 2019, In : Social psychiatry and psychiatric epidemiology. 14 p.

Associations of Polygenic Risk for Major Psychiatric Disorder With Brain Structure in Depression and Application to Stratification

Whalley, H., Harris, M., Shen, X., Gibson, J., Adams, M., Clarke, T., Lawrie, S. & McIntosh, A., 15 May 2019, In : Biological Psychiatry. 85, 10, p. S19-S20 2 p.

10Kin1day: A Bottom-Up Neuroimaging Initiative

Van Den Heuvel, M. P., Scholtens, L. H., Van Der Burgh, H. K., Agosta, F., Alloza, C., Arango, C., Auyeung, B., Baron-cohen, S., Basaia, S., Benders, M. J. N. L., Beyer, F., Booij, L., Braun, K. P. J., Filho, G. B., Cahn, W., Cannon, D. M., Chaim-avancini, T. M., Chan, S. S. M., Chen, E. Y. H., Crespo-facorro, B. & 94 othersCrone, E. A., Dannlowski, U., De Zwarte, S. M. C., Dietsche, B., Donohoe, G., Plessis, S. D., Durston, S., Díaz-caneja, C. M., Díaz-zuluaga, A. M., Emsley, R., Filippi, M., Frodl, T., Gorges, M., Graff, B., Grotegerd, D., Gąsecki, D., Hall, J. M., Holleran, L., Holt, R., Hopman, H. J., Jansen, A., Janssen, J., Jodzio, K., Jäncke, L., Kaleda, V. G., Kassubek, J., Masouleh, S. K., Kircher, T., Koevoets, M. G. J. C., Kostic, V. S., Krug, A., Lawrie, S. M., Lebedeva, I. S., Lee, E. H. M., Lett, T. A., Lewis, S. J. G., Liem, F., Lombardo, M. V., Lopez-jaramillo, C., Margulies, D. S., Markett, S., Marques, P., Martínez-zalacaín, I., Mcdonald, C., Mcintosh, A. M., Mcphilemy, G., Meinert, S. L., Menchón, J. M., Montag, C., Moreira, P. S., Morgado, P., Mothersill, D. O., Mérillat, S., Müller, H., Nabulsi, L., Najt, P., Narkiewicz, K., Naumczyk, P., Oranje, B., Ortiz-garcia De La Foz, V., Peper, J. S., Pineda, J. A., Rasser, P. E., Redlich, R., Repple, J., Reuter, M., Rosa, P. G. P., Ruigrok, A. N. V., Sabisz, A., Schall, U., Seedat, S., Serpa, M. H., Skouras, S., Soriano-mas, C., Sousa, N., Szurowska, E., Tomyshev, A. S., Tordesillas-gutierrez, D., Valk, S. L., Van Den Berg, L. H., Van Erp, T. G. M., Van Haren, N. E. M., Van Leeuwen, J. M. C., Villringer, A., Vinkers, C. C. H., Vollmar, C., Waller, L., Walter, H., Whalley, H. C., Witkowska, M., Witte, A. V., Zanetti, M. V., Zhang, R. & Lange, S. C. D., 9 May 2019, In : Frontiers in Neurology. 10

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., DeRosse, P., Djurovic, S. & 202 othersEspeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S-C., Lill, C. M., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L-P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 1 May 2019, In : Nature Communications. 10, 1, p. 2068

Genome-wide association study identifies 30 loci associated with bipolar disorder

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Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

Zeng, Y., Amador, C., Xia, C., Marioni, R., Sproul, D., Walker, R. M., Morris, S. W., Bretherick, A., Canela-Xandri, O., Boutin, T. S., Clark, D. W., Campbell, A., Rawlik, K., Hayward, C., Nagy, R., Tenesa, A., Porteous, D. J., Wilson, J. F., Deary, I. J., Evans, K. L. & 3 othersMcIntosh, A. M., Navarro, P. & Haley, C. S., 1 May 2019, In : Nature Communications. 10, 1, p. 2069

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

Grotzinger, A., Rhemtulla, M., Vlaming, R. D., Ritchie, S. J., Mallard, T. T., Hill, W. D., Hill, F., Marioni, R., McIntosh, A., Deary, I., Koellinger, P. D., Harden, K. P., Nivard, M. G. & Tucker-Drob, E. M., May 2019, In : Nature Human Behaviour. 3, 5, p. 513-525

Uncovering the genetic architecture of major depression

McIntosh, A., Sullivan, P. F. & Lewis, C. M., 3 Apr 2019, In : Neuron.

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

CommonMind Consortium, Psychiat Genomics Consortium & iPSYCH-GEMS Schizophrenia Working, Apr 2019, In : Nature Genetics. 51, 4, p. 659-+ 18 p.

Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?

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Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

Zeng, Y., Amador, C., Xia, C., Marioni, R., Sproul, D., Walker, R., Deary, I., Morris, S. W., McIntosh, A. & Haley, C., 27 Mar 2019, In : Nature Communications. 10, 1383.

Association between APOE e4 and white matter hyperintensity volume, but not total brain volume or white matter integrity

Lyall, D. M., Cox, S., Lyall, L. M., Celis-morales, C. A., Cullen, B., Mackay, D. F., Ward, J., Strawbridge, R. J., McIntosh, A., Sattar, N. A., Smith, D. J., Cavanagh, J., Deary, I. & Pell, J. P., 22 Mar 2019, In : Brain imaging and behavior.

Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health

Hill, D., Weiss, A., Liewald, D., Davies, G., Porteous, D., Hayward, C., McIntosh, A., Gale, C. & Deary, I., 13 Mar 2019, In : Molecular Psychiatry.

Leveraging DNA methylation signatures in peripheral blood as predictors of impaired respiratory function and chronic obstructive pulmonary disease.

Bermingham, M., Evans, K., McIntosh, A., Porteous, D., Deary, I., Hayward, C., Walker, R., Marioni, R., Morris, S., Rawlik, K., Zeng, Y., Campbell, A., Redmond, P., Sibley, H. & Adams, M. J., 12 Mar 2019.

Associations between vascular risk factors and brain MRI indices in UK Biobank

Cox, S., Lyall, D. M., Ritchie, S., Bastin, M., Harris, M., Buchanan, C. R., Fawns-Ritchie, C., Barbu, M., de Nooij, L., Reus, L. M., Alloza, C., Shen, X., Neilson, E., Alderson, H. L., Hunter, S., Liewald, D., Whalley, H. C., McIntosh, A., Lawrie, S., Pell, J. P. & 4 othersTucker-Drob, E. M., Wardlaw, J., Gale, C. & Deary, I., 11 Mar 2019, In : European Heart Journal.

Predicting major mental illness: ethical and practical considerations

Lawrie, S. M., Fletcher-watson, S., Whalley, H. C. & Mcintosh, A. M., 8 Mar 2019, In : BJPsych Open. 5, 2

An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

Hamilton, O., Zhang, Q., Mcrae, A. F., Walker, R., Morris, S., Redmond, P., Campbell, A., Murray, A., Porteous, D., Evans, K., McIntosh, A., Deary, I. & Marioni, R., 6 Mar 2019, In : International Journal of Obesity.

Assessment of dried blood spots for DNA methylation profiling

Walker, R. M., Macgillivray, L., Mccafferty, S., Wrobel, N., Murphy, L., Kerr, S. M., Morris, S. W., Campbell, A., Mcintosh, A. M., Porteous, D. J. & Evans, K. L., 6 Mar 2019, In : Wellcome Open Research . 4, p. 44

The influence of X chromosome variants on trait neuroticism

Luciano, M., Davies, G., Summers, K., Hill, W. D., Hayward, C., Liewald, D., Porteous, D., Gale, C., McIntosh, A. & Deary, I., 6 Mar 2019, In : Molecular Psychiatry.

Identification of common genetic risk variants for autism spectrum disorder

BUPGEN, 23AndMe Res Team, Psychiat Genomics Consortium, Maller, J., Martin, J., Martin, A., Moran, J., Nyegaard, M., Naerland, T., Palmer, D., Palotie, A., Bocker Perdersen, C., Giortz Pedersen, M., dPoterba, T., Buchhave Poulsen, J., St Poucain, B., Qvist, P., Rehnstrom, K., Reichenberg, A., Reichert, J. & 24 othersRobinson, E. B., Roeder, K., Roussos, P., Saemundsen, E., Sandin, S., Satterstrom, F. K., Smith, G. D., Stefansson, H., Steinberg, S., Stevens, C. R., Sullivan, P. F., Turley, P., Walters, G. B., Xu, X., Stefansson, K., Geschwind, D. H., Nordentoft, M., Hougaard, D. M., Werge, T., Mors, O., Mortensen, P. B., Neale, B. M., Daly, M. J. & Borglum, A. D., Mar 2019, In : Nature Genetics. 51, 3, p. 431-+ 16 p.

Pharmaco-epidemiology of antidepressant exposure in a UK cohort record-linkage study

Hafferty, J. D., Wigmore, E. M., Howard, D. M., Adams, M. J., Clarke, T., Campbell, A. I., Macintyre, D. J., Nicodemus, K. K., Lawrie, S. M., Porteous, D. J. & Mcintosh, A. M., 27 Feb 2019, In : Journal of Psychopharmacology. p. 026988111982788

Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland

Arnau soler, A., MacDonald-Dunlop, E., Adams, M. J., Clarke, T-K., MacIntyre, D., Milburn, K., Navrady, L., Scotland, G., Consortium, M. D. D. W. G. O. T. P. G., Hayward, C., McIntosh, A. & Thomson, P., 4 Feb 2019, In : Translational Psychiatry. 9, 1, 13 p., 14.

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

Howard, D. M., Adams, M. J., Clarke, T., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J., Hemani, G. & 18 othersBerger, K., Teismann, H., Rawal, R., Arolt, V., Baune, B. T., Dannlowski, U., Domschke, K., Tian, C., Hinds, D. A., Trzaskowski, M., Byrne, E. M., Ripke, S., Smith, D. J., Sullivan, P. F., Wray, N. R., Breen, G., Lewis, C. M. & Mcintosh, A. M., 4 Feb 2019, In : Nature Neuroscience. 22, 3, p. 343–352 10 p.

Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder

Trzaskowski, M., Mehta, D., Peyrot, W. J., Hawkes, D., Davies, D., Howard, D. M., Kemper, K. E., Sidorenko, J., Maier, R., Ripke, S., Mattheisen, M., Baune, B. T., Grabe, H. J., Heath, A. C., Jones, L., Jones, I., Madden, P. A. F., Mcintosh, A. M., Breen, G., Lewis, C. M. & 6 othersBørglum, A. D., Sullivan, P. F., Martin, N. G., Kendler, K. S., Levinson, D. F. & Wray, N. R., 1 Feb 2019, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence

Hill, W. D., Marioni, R., Maghzian, O., Ritchie, S. J., Hagenaars, S. P., McIntosh, A., Gale, C., Davies, G. & Deary, I., Feb 2019, In : Molecular Psychiatry. 24, 2, p. 169-181

The neurobiology of personal control during reward learning and its relation to mood

Romaniuk, L., Sandu, A., Waiter, G. D., Mcneil, C. J., Xueyi, S., Harris, M. A., Macfarlane, J. A., Lawrie, S. M., Deary, I. J., Murray, A. D., Delgado, M. R., Steele, J. D., Mcintosh, A. M. & Whalley, H. C., Feb 2019, In : Biological psychiatry. Cognitive neuroscience and neuroimaging. 4, 2, p. 190-199 10 p.

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

Wigmore, E., Hafferty, J., Hall, L., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P., Hayward, C., Smith, B. H., Hocking, L. J., Padmanabhan, S., Deary, I., Porteous, D. & 4 othersMors, O., Mattheisen, M., Nicodemus, K. & McIntosh, A., 31 Jan 2019, In : Pharmacogenomics Journal.

Association of Polygenic Liabilities for Major Depression, Bipolar Disorder, and Schizophrenia With Risk for Depression in the Danish Population

Psychiat Genomics Consortium, 30 Jan 2019, In : JAMA Psychiatry. 76, 5, p. 516-525 10 p.

Author Correction: Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

Luciano, M., Hagenaars, S. P., Davies, G., Hill, W. D., Clarke, T., Shirali, M., Harris, S. E., Marioni, R. E., Liewald, D. C., Fawns-ritchie, C., Adams, M. J., Howard, D. M., Lewis, C. M., Gale, C. R., Mcintosh, A. M. & Deary, I. J., 29 Jan 2019, In : Nature Genetics.

A validation of the diathesis-stress model for depression in Generation Scotland

Arnau soler, A., Adams, M. J., Clarke, T-K., MacIntyre, D., Milburn, K., Navrady, L., Scotland, G., Consortium, M. D. D. W. G. O. T. P. G., Hayward, C., McIntosh, A. & Thomson, P., 18 Jan 2019, In : Translational Psychiatry. 29 p.

Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder

IMAGEMEND Consortium, Karolinska Schizophrenia Project (KaSP) Consortium, 17 Jan 2019, In : Translational Psychiatry. 9, 1, p. 12

Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression

Amare, A. T., Vaez, A., Hsu, Y., Direk, N., Kamali, Z., Howard, D. M., Mcintosh, A. M., Tiemeier, H., Bültmann, U., Snieder, H. & Hartman, C. A., 9 Jan 2019, In : Molecular Psychiatry.

Association of whole-genome and NETRIN1 signaling pathway-derived polygenic risk scores for Major Depressive Disorder and white matter microstructure in UK Biobank

Barbu, M. C., Zeng, Y., Shen, X., Cox, S. R., Clarke, T., Gibson, J., Adams, M. J., Johnstone, M., Haley, C. S., Lawrie, S. M., Deary, I. J., Mcintosh, A. M. & Whalley, H. C., 1 Jan 2019, In : Biological psychiatry. Cognitive neuroscience and neuroimaging. 4, 1, p. 91-100 10 p.

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism [version 2; referees: 1 approved, 2 approved with reservations]

Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2019, In : Wellcome Open Research . 3, 11.

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (Nature Genetics, (2018), 50, 3, (381-389), 10.1038/s41588-018-0059-2)

GERAD1 Consortium: & CRESTAR Consortium, 1 Jan 2019, In : Nature Genetics.

Conditioning on a collider may or may not explain the relationship between lower neuroticism and premature mortality in Gale et al. (2017): A reply to Richardson, Davey Smith, and Munafó (2018)

Weiss, A., Gale, C., Čukić, I., Batty, G. D., McIntosh, A. & Deary, I., 2019, In : Psychological Science. 30, 4, p. 633-638

Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

23andMe Research Team, 2019, In : Communications biology. 2, p. 321

Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

Stevenson, A., McCartney, D. L., Harris, S., Taylor, A., Redmond, P., Starr, J., Zhang, Q., McRae, A. F., Wray, N. R., Spires-Jones, T., McColl, B., McIntosh, A., Deary, I. & Marioni, R., 20 Dec 2018, In : Clinical epigenetics.

How data science can advance mental health research

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Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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Reversal of proliferation deficits caused by chromosome 16p13.11 microduplication through targeting NFκB signaling: an integrated study of patient-derived neuronal precursor cells, cerebral organoids and in vivo brain imaging

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Epigenetic signatures of starting and stopping smoking

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Genome-wide association study meta-analysis of the Alcohol Use Disorders Identification Test (AUDIT) in two population-based cohorts (N=141,932)

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Brain Network Structural Covariance in Youth at High Familial Risk for Bipolar Disorder

Heinze, K., McIntosh, A., Wood, S., Harris, M., Hawkins, E. & Sibley, H., Oct 2018, In : Early Intervention in Psychiatry. 12, p. 67-67 1 p.

Resting-State Connectivity and Its Association With Cognitive Performance, Educational Attainment, and Household Income in the UK Biobank

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Epigenetic prediction of complex traits and death

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DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness

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Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression

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Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder: Running title: Identification of three loci associated with risk of major depressive disorder

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DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies

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Erratum: Mental health in UK Biobank: development, implementation and results from an online questionnaire completed by 157 366 participants - CORRIGENDUM

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Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association with Mood Instability

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Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders

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Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

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Do Depression and Stressful Events Cause Premature Aging?

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Genetic contributions to trail making test performance in UK Biobank

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Polygenic risk for schizophrenia, transition and cortical gyrification: a high-risk study

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Rediscovering the value of families for psychiatric genetics research

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Analysis of shared heritability in common disorders of the brain

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Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer’s disease

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DNA sequence level analyses reveal potential phenotypic modifiers in a large family with psychiatric disorders.

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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

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Sex differences in the adult human brain: Evidence from 5216 UK Biobank participants

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Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium

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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

Howard, D. M., Adams, M. J., Shirali, M., Clarke, T-K., Marioni, R., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M., Wigmore, E., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C., Breen, G., Deary, I. & 1 othersMcIntosh, A., 16 Apr 2018, In : Nature Communications. 9, 1, p. 1-10 1470.

Mental Health in UK Biobank – development, implementation and results from an online questionnaire completed by 157,366 participants

Davis, K., Coleman, J., Adams, M. J., Allen, N., Breen, G., Cullen, B., Dickens, C., Fox, E., Graham, N., Holliday, J., Howard, L. M., John, A., Lee, W., McCabe, R., McIntosh, A., Pearsall, R., Sudlow, C., Ward, J., Zammit, S. & Hotopf, M., 3 Apr 2018, In : BJPsych Open.

Altered DNA methylation associated with a translocation linked to major mental illness

McCartney, D. L., Walker, R. M., Morris, S. W., Anderson, S. M., Duff, B. J., Marioni, R. E., Millar, J. K., McCarthy, S. E., Ryan, N. M., Lawrie, S. M., Watson, A. R., Blackwood, D. H. R., Thomson, P. A., McIntosh, A. M., McCombie, W. R., Porteous, D. J. & Evans, K. L., 19 Mar 2018, In : npj Schizophrenia. 4, 1, p. 5

Increased gyrification in schizophrenia and non affective first episode of psychosis

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Diffusion tensor imaging correlates of early markers of depression in youth at high-familial risk for bipolar disorder

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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

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Genetic and environmental contributions to psychological resilience and coping

Navrady, L. B., Zeng, Y., Clarke, T-K., Adams, M. J., Howard, D. M., Deary, I. J. & McIntosh, A. M., 15 Feb 2018, In : Wellcome Open Research . 3, 12, p. 12

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

Clarke, T., Zeng, Y., Navrady, L., Xia, C., Haley, C., Campbell, A., Navarro, P., Amador, C., Adams, M. J., Howard, D. M., Soler, A., Hayward, C., Thomson, P. A., Smith, B. H., Padmanabhan, S., Hocking, L. J., Hall, L. S., Porteous, D. J., Deary, I. J. & Mcintosh, A. M., 14 Feb 2018, In : Wellcome Open Research . 3, p. 11

Cohort Profile: Stratifying Resilience and Depression Longitudinally (STRADL): A questionnaire follow-up of Generation Scotland: Scottish Family Health Study (GS:SFHS)

Navrady, L., Wolters, M., MacIntyre, D., Clarke, T-K., Campbell, A., Murray, A., Evans, K., Seckl, J., Haley, C., Milburn, K., Wardlaw, J., Porteous, D., Deary, I. & McIntosh, A., 1 Feb 2018, In : International Journal of Epidemiology. 47, 1, p. 13-14g

A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N = 223,773)

Meng, W., Adams, M. J., Hebert, H. L., Deary, I. J., Mcintosh, A. M. & Smith, B. H., 31 Jan 2018, In : EBioMedicine.

Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank

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Genomic analysis of family data reveals additional genetic effects on intelligence and personality

Hill, W. D., Arslan, R. C., Xia, C., Luciano, M., Amador, C., Navarro, P., Hayward, C., Nagy, R., Porteous, D., McIntosh, A., Deary, I., Haley, C. & Penke, L., 10 Jan 2018, In : Molecular Psychiatry.

Brain cortical characteristics of lifetime cognitive ageing

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Genetic contributions to self-reported tiredness

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Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

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Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

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Genetic risk of Major Depressive Disorder: the moderating and mediating effects of neuroticism and psychological resilience on clinical and self-reported depression

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Association Between Schizophrenia-Related Polygenic Liability and the Occurrence and Level of Mood-Incongruent Psychotic Symptoms in Bipolar Disorder

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Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains

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Self-Reported Medication Use Validated Through Record Linkage to National Prescribing Data

Hafferty, J., Campbell, A., Navrady, L., Adams, M. J., Macintyre, D., Lawrie, S., Nicodemus, K., Porteous, D. J. & McIntosh, A., 30 Oct 2017, In : Journal of clinical epidemiology.

Verbal working memory and functional large-scale networks in schizophrenia

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Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

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Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group

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CLINICAL AND GENETIC RE-EVALUATION OF THE SCOTTISH DISCI TRANSLOCATION FAMILY

Thomson, P., Duff, B., McCarthy, S., Ryan, N. M., Whalley, H. C., de la Bastide, M., Morris, S. W., McIntosh, A. M., Evans, K. L., Lawrie, S. M., Blackwood, D. H. R., McCombie, W. R. & Porteous, D. J., Oct 2017, In : European Neuropsychopharmacology. 27, p. S276-S277 2 p.

SHARED GENETIC ARCHITECTURE BETWEEN COGNITION AND REGIONAL BRAIN VOLUME

Wigmore, E., Clarke, T., Nicodemus, K. & McIntosh, A., Oct 2017, In : European Neuropsychopharmacology. 27, p. S306-S307 2 p.

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. A. F., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A., Baune, B. T., Breen, G. & 10 othersLevinson, D. F., Lewis, C. M., Martin, N. G., Nelson, E. N., Boomsma, D. I., Grabe, H. J., Wray, N. R., Penninx, B. W. J. H., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & McIntosh, A., 21 Sep 2017, In : Biological Psychiatry.

Electronic health record and genome-wide genetic data in Generation Scotland participants

Kerr, S., Campbell, A., Marten, J., Vitart, V., McIntosh, A., Porteous, D. & Hayward, C., 18 Sep 2017, In : Wellcome Open Research . 2, p. 85

Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with Major Depressive Disorder

Zeng, Y., Navarro, P., Shirali, M., Howard, D., Adams, M., Hall, L., Clarke, T-K., Thomson, P., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B., Milaneschi, Y., Baune, B. T. & 19 othersAir, T., Hottenga, J-J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Deary, I., Porteous, D., Haley, C. & McIntosh, A., 1 Sep 2017, In : Biological Psychiatry. 82, 5, p. 312-321

A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

Ranlund, S., Calafato, S., Thygesen, J. H., Lin, K., Cahn, W., Crespo-Facorro, B., de Zwarte, S. M. C., Díez, Á., Di Forti, M., Iyegbe, C., Jablensky, A., Jones, R., Hall, M-H., Kahn, R., Kalaydjieva, L., Kravariti, E., McDonald, C., McIntosh, A. M., McQuillin, A., Picchioni, M. & 14 othersPrata, D. P., Rujescu, D., Schulze, K., Shaikh, M., Toulopoulou, T., van Haren, N., van Os, J., Vassos, E., Walshe, M., Lewis, C., Murray, R. M., Powell, J., Bramon, E. & GROUP, 29 Aug 2017, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics.

Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank

Howard, D. M., Adams, M. J., Clarke, T., Wigmore, E. M., Zeng, Y., Hagenaars, S. P., Lyall, D. M., Thomson, P. A., Evans, K. L., Porteous, D. J., Nagy, R., Hayward, C., Haley, C. S., Smith, B. H., Murray, A. D., Batty, G. D., Deary, I. J. & Mcintosh, A. M., 10 Aug 2017, In : Wellcome Open Research . 10 p., 261.

Subcortical volume and white matter integrity abnormalities in major depressive disorder: Findings from UK Biobank imaging data

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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., Gujral, M., Brandler, W. M., Malhotra, D., Wang, Z., Fajarado, K. V. F., Maile, M. S., Ripke, S., Agartz, I., Albus, M., Alexander, M. & 31 othersAmin, F., Atkins, J., Bacanu, S-A., Belliveau, R. A., Bergen, S. E., Bertalan, M., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Bulik-Sullivan, B. K., Byerley, W. F., Cahn, W., Cai, G., Cairns, M. J., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Cheng, W-T., Cloninger, C. R., Cohen, D. J., Cormican, P., McIntosh, A., Nicodemus, K., Blackwood, D. H. R. & Psychosis Endophenotypes International Consortium, 11 Jul 2017, In : Nature Genetics. 49, 1, p. 27-35 9 p.

The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability

Singh, T., Walters, J. T. R., Johnstone, M., Curtis, D., Suvisaari, J., Torniainen, M., Rees, E., Iyegbe, C., Blackwood, D., Mcintosh, A. M., Kirov, G., Geschwind, D., Murray, R. M., Di Forti, M., Bramon, E., Gandal, M., Hultman, C. M., Sklar, P., Palotie, A., Sullivan, P. F. & 3 othersO'donovan, M. C., Owen, M. J. & Barrett, J. C., 26 Jun 2017, In : Nature Genetics.

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Witt, S. H., Streit, F., Jungkunz, M., Frank, J., Awasthi, S., Reinbold, C. S., Treutlein, J., Degenhardt, F., Forstner, A. J., Heilmann-Heimbach, S., Dietl, L., Schwarze, C. E., Schendel, D., Strohmaier, J., Abdellaoui, A., Adolfsson, R., Air, T. M., Akil, H., Alda, M., Alliey-Rodriguez, N. & 31 othersAndreassen, O. A., Babadjanova, G., Bass, N. J., Bauer, M., Baune, B. T., Bellivier, F., Bergen, S., Bethell, A., Biernacka, J. M., Blackwood, D. H. R., Boks, M. P., Boomsma, D. I., Borglum, A. D., Borrmann-Hassenbach, M., Brennan, P., Budde, M., Buttenschon, H. N., Byrne, E. M., Cervantes, P., Clarke, T-K., Craddock, N., Cruceanu, C., Curtis, D., Czerski, P. M., Dannlowski, U., Davis, T., de Geus, E. J. C., Di Florio, A., Djurovic, S., McIntosh, A. M. & Psychiat Genomics Consortium, 20 Jun 2017, In : Translational Psychiatry. 7, 9 p., 1155.

Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia

Teng, S., Thomson, P. A., Mccarthy, S., Kramer, M., Muller, S., Lihm, J., Morris, S., Soares, D. C., Hennah, W., Harris, S., Camargo, L. M., Malkov, V., Mcintosh, A. M., Millar, J. K., Blackwood, D. H., Evans, K. L., Deary, I. J., Porteous, D. J. & Mccombie, W. R., 20 Jun 2017, In : Molecular Psychiatry.

Molecular genetic contributions to self-rated health

Harris, S., Hagenaars, S., Davies, G., Hill, W. D., Liewald, D., Ritchie, S. J., Marioni, R., Sudlow, C., Wardlaw, J., McIntosh, A., Deary, I., Gale, C., METASTROKE consortium, International Consortium for Blood Pressure, CHARGE consortium Aging and Longevity Group & CHARGE consortium Cognitive Group, Jun 2017, In : International Journal of Epidemiology. 46, 3, p. 994-1009

Cognitive Performance in Major Depressive Disorder in Generation Scotland: The Scottish Family Health Study (GS:SFHS)

Meijsen, J., Campbell, A., McIntosh, A., Porteous, D., Deary, I., Marioni, R. & Nicodemus, K., 15 May 2017, In : Biological Psychiatry. 81, 10, p. S217-S217 1 p.

Gene-By-Environment Analyses Reveal Obstetric Complications Interact with Genetics to Influence Psychopathology and Personality

Gountouna, V-E., Hafferty, J., Campbell, A., Porteous, D., McIntosh, A. & Nicodemus, K., 15 May 2017, In : Biological Psychiatry. 81, 10, p. S368-S368 1 p.

Cortical abnormalities in bipolar disorder: An MRI analysis of 6,503 individuals from the ENIGMA-Bipolar Disorder Working Group

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Longitudinal differences in white matter integrity in youth at high familial risk for bipolar disorder

Ganzola, R., Nickson, T., Bastin, M. E., Giles, S., Macdonald, A., Sussmann, J., McIntosh, A. M., Whalley, H. C. & Duchesne, S., May 2017, In : Bipolar Disorders. 19, 3

Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data

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Genetic effects influencing risk for major depressive disorder in China and Europe

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Corrigendum: Genetic contributions to self-reported tiredness

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Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

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Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

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Using Polygenic Risk Scores to Establish Endophenotypes: Considerations and Current Constraints

Glahn, D. C. & McIntosh, A. M., 6 Mar 2017, In : Biological psychiatry. Cognitive neuroscience and neuroimaging. 2, 2, p. 113-114 2 p.

Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: Analysis of a family-based cohort and twin study

van Hecke, O., Hocking, L. J., Torrance, N., Campbell, A., Padmanabhan, S., Porteous, D. J., McIntosh, A. M., Burri, A. V., Tanaka, H., Williams, F. M. K. & Smith, B. H., 22 Feb 2017, In : PLoS ONE. 12, 2, p. e0170653

Associations between single and multiple cardiometabolic diseases and cognitive abilities in 474 129 UK Biobank participants

Lyall, D. M., Celis-morales, C. A., Anderson, J., Gill, J. M. R., Mackay, D. F., Mcintosh, A. M., Smith, D. J., Deary, I. J., Sattar, N. & Pell, J. P., 21 Feb 2017, In : European Heart Journal. 38, 8, p. 577-583

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway is Associated with Major Depressive Disorder

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Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

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Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank

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Novel genetic loci associated with hippocampal volume

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Intelligence and neuroticism in relation to depression and psychological distress: Evidence from two large population cohorts

Navrady, L., Ritchie, S. J., Chan, S. W. Y., Kerr, D., Adams, M., Hawkins, E., Porteous, D., Deary, I., Gale, C., Batty, G. D. & McIntosh, A., 17 Jan 2017, In : European Psychiatry. 43, p. 58-65

The Common Genetic Architecture of Anxiety Disorders

Purves, K. L., Coleman, J. R. I., Rayner, C., Hettema, J. M., Deckert, J., McIntosh, A. M., Nicodemus, K. K., Breen, G. & Eley, T. C., 1 Jan 2017, bioRxiv, at Cold Spring Harbor Laboratory.

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112,117).

Clarke, T-K., Adams, M. J., Davies, G., Howard, D. M., Hall, L., Padmanabhan, S., Murray, A. D., Smith, B. H., Campbell, A., Hayward, C., Porteous, D., Deary, I. & McIntosh, A., 2017, In : Molecular Psychiatry. 22, p. 1376-1384

When is higher neuroticism protective against premature death? Findings from UK Biobank

Gale, C., Cukic, I., Batty, G. D., McIntosh, A., Weiss, A. & Deary, I., 2017, In : Psychological Science. 28, 9, p. 1345-1357

Effects of environmental risks and polygenic loading for schizophrenia on cortical thickness

Neilson, E., Bois, C., Gibson, J., Duff, B., Watson, A., Roberts, N., Brandon, N. J., Dunlop, J., Hall, J., McIntosh, A. M., Whalley, H. C. & Lawrie, S. M., 15 Dec 2016, In : Schizophrenia Research.

Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

Zeng, Y., Navarro, P., Xin, C., Amador, C., Fernandez-pujals, A. M., Thomson, P. A., Campbell, A., Nagy, R., Clarke, T., Hafferty, J. D., Smith, B. H., Hocking, L. J., Padmanabhan, S., Hayward, C., Macintyre, D. J., Porteous, D. J., Haley, C. S. & Mcintosh, A. M., 14 Dec 2016, In : EBioMedicine. 14, p. 161-167

An Analysis of Two Genome-Wide Association Meta-Analyses Identifies a New Locus for Broad Depression Phenotype

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Molecular genetic contributions to social deprivation and household income in UK biobank

Hill, W. D., Hagenaars, S. P., Marioni, R. E., Harris, S. E., Liewald, D. C. M., Davies, G., Okbay, A., McIntosh, A. M., Gale, C. R. & Deary, I. J., 21 Nov 2016, In : Current biology : CB. 26, 22, p. 3083-3089

Dissection of Major Depressive Disorder using polygenic risk scores for Schizophrenia in two independent cohorts

Sibley, H., Adams, M., Hall, L. S., Clarke, T-K., Fernandez-Pujals, A. M., Gibson, J., Wigmore, E., Hafferty, J., Hagenaars, S., Davies, G., Campbell, A., Hayward, C., Lawrie, S., Porteous, D., Deary, I. & McIntosh, A., 1 Nov 2016, In : Translational Psychiatry. 6, 11, p. e938

Deactivation in Anterior Cingulate Cortex during facial processing in young individuals with high familial risk and early development of depression: fMRI findings from the Scottish Bipolar Family Study

Chan, W., Sussmann, J., Romaniuk, L., Stewart, T., Lawrie, S., Hall, J., McIntosh, A. & Sibley, H., Nov 2016, In : Journal of Child Psychology and Psychiatry. 57, 11, p. 1277-1286 10 p.

Invited Commentary on Stewart and Davis " 'Big data' in mental health research-current status and emerging possibilities"

Hafferty, J. D., Smith, D. J. & McIntosh, A. M., 25 Oct 2016, In : Social psychiatry and psychiatric epidemiology.

Novel genetic loci underlying human intracranial volume identified through genome-wide association

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Data science for mental health – a UK perspective on a global challenge

McIntosh, A., Stewart, R., John, A., Smith, D. J., Davis, K., Sudlow, C., Corvin, A., Nicodemus, K., Kingdon, D., Hassan, L., Hotopf, M., Lawrie, S., Russ, T., Geddes, J. R., Wolpert, M., Wölbert, E. & Porteous, D., Oct 2016, In : Lancet Psychiatry. 3, 10, p. 993-998 6 p.

Social responsiveness to inanimate entities: Altered white matter in a ‘social synaesthesia’

Simner, J., Rehme, M. K., Carmichael, D., Bastin, M., Sprooten, E., McIntosh, A., Lawrie, S. & Zedler, M., Oct 2016, In : Neuropsychologia. 91, p. 282-289 8 p.

Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip

Mccartney, D., Walker, R., Morris, S. W., McIntosh, A., Porteous, D. & Evans, K., 1 Sep 2016, In : Genomics Data. 9, p. 22-24

Genetic and environmental risk for chronic pain and the contribution of risk variants for major depressive disorder: a family-based mixed-model analysis

McIntosh, A., Hall, L. S., Zeng, Y., Adams, M. J., Gibson, J., Wigmore, E., Hagenaars, S., Davies, G., Fernandez-Pujals, A. M., Campbell, A., Clarke, T-K., Hayward, C., Haley, C., Porteous, D., Deary, I., Smith, D. J., Nicholl, B. I., Hinds, D. A., Jones, A. V., Scollen, S. & 3 othersMeng, W., Smith, B. H. & Hocking, L. J., 16 Aug 2016, In : PLOS Medicine. 13, 8, e1002090.

Age-dependent pleiotropy between general cognitive function and major psychiatric disorders

Hill, W. D., Davies, G., Liewald, D. C., Mcintosh, A. M. & Deary, I. J., 15 Aug 2016, In : Biological Psychiatry. 80, 4, p. 266-273

Psychological distress, neuroticism, and cause-specific mortality: Early prospective evidence from UK Biobank

Batty, G. D., McIntosh, A., Russ, T., Deary, I. & Gale, C., 12 Aug 2016, In : Journal of Epidemiology & Community Health. 70, 11, p. 1136-1139

Balanced translocation linked to psychiatric disorder, glutamate and cortical structure/function

Thomson, P., Duff, B., Blackwood, D., Romaniuk, L., Watson, A. R., Sibley, H., Li, X., Dauvermann, M. R., Moorhead, T., Bois, C., Ryan, N., Redpath, H., Hall, L. S., Morris, S. W., van Beek, E., Roberts, N., Porteous, D., St Clair, D., Whitcher, B., Dunlop, J. & 5 othersBrandon, N. J., Hughes, Z., Hall, J., McIntosh, A. & Lawrie, S., 10 Aug 2016, In : npj Schizophrenia.

Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort

Clarke, T-K., Obsteter, J., Hall, L. S., Hayward, C., Thomson, P. A., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., 2 Aug 2016, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 174, 3, p. 227-234

Preliminary assessment of pre-morbid DNA methylation in individuals at high genetic risk of mood disorders

Walker, R., Sussmann, J., Sibley, H., Ryan, N., Porteous, D., McIntosh, A. & Evans, K., 21 Jul 2016, In : Bipolar Disorders.

Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research

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Prospective longitudinal voxel-based morphometry study of Major Depressive Disorder in young individuals at high familial risk

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Genome-wide analysis of over 106,000 individuals identifies 9 neuroticism-associated loci

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Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

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Common and distinct patterns of grey-matter volume alteration in major depression and bipolar disorder: evidence from voxel-based meta-analysis

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Childhood adversity and hippocampal and amygdala volumes in a population at familial high risk of schizophrenia

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Machine learning can improve prediction of lifetime major depressive disorder in the Generation Scotland: Scottish Family Health Study

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Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group

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Pleiotropy between neuroticism and physical and mental health: Findings from 108038 men and women in UK Biobank

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Cognitive Test Scores in UK Biobank: Data Reduction in 480,416 Participants and Longitudinal Stability in 20,346 Participants

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Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants

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Cardiometabolic disease and features of depression and bipolar disorder: population-based, cross-sectional study

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Computational META-analysis of statistical parametric maps in major depression

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Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women

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Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

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Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort: Alcohol dependence cognition

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Prospective longitudinal study of subcortical brain volumes in individuals at high familial risk of mood disorders with or without subsequent onset of depression

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Response to Dr Fried & Dr Kievit, and Dr Malhi et al

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Early-life predictors of resilience and related outcomes up to 66 years later in the 6-day sample of the 1947 Scottish mental survey

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Schizophrenia risk from complex variation of complement component 4

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Subcortical volumetric abnormalities in bipolar disorder

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Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

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Polygenic risk for coronary artery disease is associated with cognitive ability in older adults

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Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

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DNA methylation in a Scottish family multiply affected by bipolar disorder and major depressive disorder

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Low birth weight and features of neuroticism and mood disorder in 83 545 participants of the UK Biobank cohort

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Childhood adversity and cortical thickness and surface area in a population at familial high risk of schizophrenia

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Epidemiology and Heritability of Major Depressive Disorder, Stratified by Age of Onset, Sex, and Illness Course in Generation Scotland: Scottish Family Health Study (GS:SFHS)

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Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants

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Neurocognition in individuals at high familial risk of mood disorders with or without subsequent onset of depression

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Transcranial Magnetic Stimulation for Schizophrenia

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Ethnic differences in the association between depression and chronic pain: cross sectional results from UK Biobank

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Copy-number variations in DISC1 and DISC1-interacting partners in major mental illness

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Machine learning can improve prediction of depression in Generation Scotland

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The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia

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New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

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White matter integrity and its association with affective and interpersonal symptoms in borderline personality disorder

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Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

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Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group

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Effects of a balanced translocation between chromosomes 1 and 11 disrupting the DISC1 locus on white matter integrity

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Current Versus Lifetime Depression, APOE Variation, and Their Interaction on Cognitive Performance in Younger and Older Adults

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Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium

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Endophenotypes for Depression and their Value in Gene Discovery

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Family load impacts orbitofrontal volume in first-episode schizophrenia

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The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects

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Transcranial magnetic stimulation (TMS) for schizophrenia

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Common genetic variants influence human subcortical brain structures

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Dysfunction of emotional brain systems in individuals at high risk of mood disorder with depression and predictive features prior to illness

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Genetics and Neurobiology of Anxiety and Depression

McIntosh, A., Whalley, H. C. & Lawrie, S. M., 28 Mar 2015, In : European Psychiatry. 30, 1 p.

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

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Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data

Kochunov, P., Jahanshad, N., Marcus, D., Winkler, A., Sprooten, E., Nichols, T. E., Wright, S. N., Hong, L. E., Patel, B., Behrens, T., Jbabdi, S., Andersson, J., Lenglet, C., Yacoub, E., Moeller, S., Auerbach, E., Ugurbil, K., Sotiropoulos, S. N., Brouwer, R. M., Landman, B. & 33 othersLemaitre, H., den Braber, A., Zwiers, M. P., Ritchie, S., van Hulzen, K., Almasy, L., Curran, J., deZubicaray, G. I., Duggirala, R., Fox, P., Martin, N. G., McMahon, K. L., Mitchell, B., Olvera, R. L., Peterson, C., Starr, J., Sussmann, J., Wardlaw, J., Wright, M., Boomsma, D. I., Kahn, R., de Geus, E. J. C., Williamson, D. E., Hariri, A., van 't Ent, D., Bastin, M. E., McIntosh, A., Deary, I. J., Hulshoff Pol, H. E., Blangero, J., Thompson, P. M., Glahn, D. C. & Van Essen, D. C., 4 Mar 2015, In : NeuroImage. 111, p. 300-311 12 p.

Preliminary investigation of miRNA expression in individuals at high familial risk of bipolar disorder

Walker, R. M., Rybka, J., Anderson, S. M., Torrance, H. S., Boxall, R., Sussmann, J. E., Porteous, D. J., McIntosh, A. M. & Evans, K. L., Mar 2015, In : Journal of Psychiatric Research. 62

Cortical Surface Area Differentiates Familial High Risk Individuals Who Go on to Develop Schizophrenia

Bois, C., Ronan, L., Levita, L., Whalley, H. C., Giles, S., McIntosh, A. M., Fletcher, P. C., Owens, D. C., Johnstone, E. C. & Lawrie, S. M., 7 Feb 2015, In : Biological Psychiatry.

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Maier, R., Moser, G., Chen, G-B., Ripke, S., Coryell, W., Potash, J. B., Scheftner, W. A., Shi, J., Weissman, M. M., Hultman, C. M., Landén, M., Levinson, D. F., Kendler, K. S., Smoller, J. W., Wray, N. R., Lee, S. H., Cross-Disorder Working Group of the Psychiatric Genomics Consortium & McIntosh, A., 5 Feb 2015, In : American Journal of Human Genetics. 96, 2, p. 283-94 12 p.

Impact of cross-disorder polygenic risk on frontal brain activation with specific effect of schizophrenia risk

Whalley, H. C., Hall, L., Romaniuk, L., Macdonald, A., Lawrie, S. M., Sussmann, J. E. & McIntosh, A. M., Feb 2015, In : Schizophrenia Research. 161, 2-3, p. 484–489

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

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Chronic multisite pain in major depression and bipolar disorder: cross-sectional study of 149,611 participants in UK Biobank

Nicholl, B. I., Mackay, D., Cullen, B., Martin, D. J., Ul-Haq, Z., Mair, F. S., Evans, J., McIntosh, A. M., Gallagher, J., Roberts, B., Deary, I. J., Pell, J. P. & Smith, D. J., 10 Dec 2014, In : BMC Psychiatry. 14, 1, p. 350

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., Kähler, A. K., Hultman, C. M., Purcell, S. M., McCarroll, S. A., Daly, M., Pasaniuc, B., Sullivan, P. F., Neale, B. M., Wray, N. R., Raychaudhuri, S. & 3 othersPrice, A. L., Schizophrenia Working Group of the Psychiatric Genomics Consortium & McIntosh, A., 6 Nov 2014, In : American Journal of Human Genetics. 95, 5, p. 535-52 18 p.

Cortical Thickness in Individuals at High Familial Risk of Mood Disorders as They Develop Major Depressive Disorder

Papmeyer, M., Giles, S., Sussmann, J. E., Kielty, S., Stewart, T., Lawrie, S. M., Whalley, H. C. & McIntosh, A. M., 30 Oct 2014, In : Biological Psychiatry.

A survey of rare coding variants in candidate genes in schizophrenia by deep sequencing

Hu, X., Zhang, B., Liu, W., Paciga, S., He, W., Lanz, T. A., Kleiman, R., Dougherty, B., Hall, S. K., McIntosh, A. M., Lawrie, S. M., Power, A., John, S. L., Blackwood, D., St Clair, D. & Brandon, N. J., Oct 2014, In : Molecular Psychiatry. 19, 8, p. 857-8 2 p.

Biological insights from 108 schizophrenia-associated genetic loci

Nicodemus, K. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, 24 Jul 2014, In : Nature. 511, p. 421-427 7 p.

Structural magnetic resonance imaging markers of susceptibility and transition to schizophrenia: A review of familial and clinical high risk population studies

Bois, C., Whalley, H., McIntosh, A., Lawrie, S. & McIntosh, A., 21 Jul 2014, In : Journal of Psychopharmacology.

Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling

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708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits

Thomson, P. A., Parla, J. S., McRae, A. F., Kramer, M., Ramakrishnan, K., Yao, J., Soares, D. C., McCarthy, S., Morris, S. W., Cardone, L., Cass, S., Ghiban, E., Hennah, W., Evans, K. L., Rebolini, D., Millar, J. K., Harris, S. E., Starr, J. M., MacIntyre, D. J., Generation Scotland & 7 othersMcIntosh, A. M., Watson, J. D., Deary, I. J., Visscher, P. M., Blackwood, D. H., McCombie, W. R. & Porteous, D. J., 1 Jun 2014, In : Molecular Psychiatry. 19, 6, p. 668-675 8 p.

Identification of pathways for bipolar disorder: a meta-analysis

Nurnberger, J. I., Koller, D. L., Jung, J., Edenberg, H. J., Foroud, T., Guella, I., Vawter, M. P., Kelsoe, J. R., Psychiatric Genomics Consortium Bipolar Group & McIntosh, A., Jun 2014, In : JAMA Psychiatry. 71, 6, p. 657-64 8 p.

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., Franke, B., Wright, M. J., Martin, N. G., Agartz, I., Alda, M., Alhusaini, S., Almasy, L., Almeida, J., Alpert, K., Andreasen, N. C., Andreassen, O. A. & 34 othersApostolova, L. G., Appel, K., Armstrong, N. J., Aribisala, B., Bastin, M. E., Bauer, M., Bearden, C. E., Bergmann, O., Binder, E. B., Blangero, J., Bockholt, H. J., Boen, E., Bois, C., Boomsma, D. I., Booth, T., Bowman, I. J., Bralten, J., Deary, I. J., Hall, J., Lawrie, S. M., Liewald, D. C., Lopez, L. M., Luciano, M., McIntosh, A. M., Royle, N. A., Smith, C., Starr, J. M., Sussmann, J., Wardlaw, J. M., Whalley, H. C., Alzheimer's Dis Neuroimaging, EPIGEN Consortium, IMAGEN Consortium & Saguenay Youth Study SYS Grp, Jun 2014, In : Brain imaging and behavior. 8, 2, p. 153-182 30 p.

Corrigendum to Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA-DTI working group [NeuroImage 81 (2013) 455-469]

Jahanshad, N., Kochunov, P. V., Sprooten, E., Mandl, R. C., Nichols, T. E., Almasy, L., Blangero, J., Brouwer, R. M., Curran, J. E., de Zubicaray, G. I., Duggirala, R., Fox, P. T., Hong, L. E., Landman, B. A., Martin, N. G., McMahon, K. L., Medland, S. E., Mitchell, B. D., Olvera, R. L., Peterson, C. P. & 11 othersStarr, J. M., Sussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Pol, H. E. H., Bastin, M. E., McIntosh, A. M., Deary, I. J., Thompson, P. M. & Glahn, D. C., 15 Apr 2014, In : NeuroImage. 90, p. 470-471 2 p.

Two-back makes step forward in brain imaging genomics

McIntosh, A., Deary, I. & Porteous, D. J., 5 Mar 2014, In : Neuron. 81, 5, p. 959-61 3 p.

A Genome-wide Association Analysis of a Broad Psychosis Phenotype Identifies Three Loci for Further Investigation

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DISC1 as a genetic risk factor for schizophrenia and related major mental illness: response to Sullivan: response to Sullivan

Porteous, D. J., Thomson, P. A., Millar, J. K., Evans, K. L., Hennah, W., Soares, D. C., McCarthy, S., McCombie, W. R., Clapcote, S. J., Korth, C., Brandon, N. J., Sawa, A., Kamiya, A., Roder, J. C., Lawrie, S. M., McIntosh, A. M., St Clair, D. & Blackwood, D. H., Feb 2014, In : Molecular Psychiatry. 19, 2, p. 141-143 3 p.

Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci

Andreassen, O. A., Harbo, H. F., Wang, Y., Thompson, W. K., Schork, A. J., Mattingsdal, M., Zuber, V., Bettella, F., Ripke, S., Kelsoe, J. R., Kendler, K. S., O'Donovan, M. C., Sklar, P., McEvoy, L. K., Desikan, R. S., Lie, B. A., Djurovic, S., Dale, A. M., The Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups & McIntosh, A., 28 Jan 2014, In : Molecular Psychiatry.

Combining Meta- and mega-analytic approaches for multi-site diffusion imaging based genetic studies: From the enigma-DTI working group

Jahanshad, N., Kochunov, P., Nichols, T. E., Sprooten, E., Mandl, R. C., Almasy, L., Brouwer, R. M., Curran, J. E., De Zubicaray, G. I., Dimitrova, R., Fox, P. T., Hong, L. E., Landman, B. A., Lemaitre, H., Lopez, L., Martin, N. G., McMahon, K. L., Mitchell, B. D., Olvera, R. L., Peterson, C. P. & 17 othersSussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Wright, S. N., Bastin, M. E., McIntosh, A. M., Boomsma, D. I., Kahn, R. S., Den Braber, A., Deary, I. J., Pol, H. E. H., Williamson, D., Blangero, J., Van't Ent, D., Glahn, D. C. & Thompson, P. M., 1 Jan 2014, 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014. Institute of Electrical and Electronics Engineers Inc., p. 1234-1238 5 p. 6868099

Altered Amygdala Connectivity Within the Social Brain in Schizophrenia

Mukherjee, P., Whalley, H. C., McKirdy, J. W., Sprengelmeyer, R., Young, A. W., McIntosh, A. M., Lawrie, S. M. & Hall, J., Jan 2014, In : Schizophrenia Bulletin. 40, 1, p. 152-160 9 p.

Schizophrenia genetic variants are not associated with intelligence

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Cortical thickness in first-episode schizophrenia patients and individuals at high familial risk: A cross-sectional comparison

Sprooten, E., Papmeyer, M., Smyth, A. M., Vincenz, D., Honold, S., Conlon, G. A., Moorhead, T. W. J., Job, D., Whalley, H. C., Hall, J., McIntosh, A. M., Owens, D. C. G., Johnstone, E. C. & Lawrie, S. M., Dec 2013, In : Schizophrenia Research. 151, 1-3, p. 259-264 6 p.

Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA-DTI working group

Jahanshad, N., Kochunov, P. V., Sprooten, E., Mandl, R. C., Nichols, T. E., Almasy, L., Blangero, J., Brouwer, R. M., Curran, J. E., de Zubicaray, G. I., Duggirala, R., Fox, P. T., Hong, L. E., Landman, B. A., Martin, N. G., McMahon, K. L., Medland, S. E., Mitchell, B. D., Olvera, R. L., Peterson, C. P. & 11 othersStarr, J. M., Sussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Hulshoff Pol, H. E., Bastin, M. E., McIntosh, A. M., Deary, I. J., Thompson, P. M. & Glahn, D. C., 1 Nov 2013, In : NeuroImage. 81, p. 455-469 15 p.

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Ripke, S., O'Dushlaine, C., Chambert, K., Moran, J. L., Kähler, A. K., Akterin, S., Bergen, S. E., Collins, A. L., Crowley, J. J., Fromer, M., Kim, Y., Lee, S. H., Magnusson, P. K. E., Sanchez, N., Stahl, E. A., Williams, S., Wray, N. R., Xia, K., Bettella, F., Borglum, A. D. & 31 othersBulik-Sullivan, B. K., Cormican, P., Craddock, N., de Leeuw, C., Durmishi, N., Gill, M., Golimbet, V., Hamshere, M. L., Holmans, P., Hougaard, D. M., Kendler, K. S., Lin, K., Morris, D. W., Mors, O., Mortensen, P. B., Neale, B. M., O'Neill, F. A., Owen, M. J., Milovancevic, M. P., Posthuma, D., Powell, J., Richards, A. L., Riley, B. P., Ruderfer, D., Rujescu, D., Sigurdsson, E., Silagadze, T., Hall, J., Lawrie, S., McIntosh, A. & Multicenter Genetic Studies of Schizophrenia Consortium, Oct 2013, In : Nature Genetics. 45, 10, p. 1150-9 10 p.

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 31 othersAzevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H. R., Bloss, C. S., Boehnke, M., MacIntyre, D. J., McGhee, K. A., McIntosh, A., Muir, W. J., Pickard, B. S., Visscher, P. M., Cross-Disorder Group of the Psychiatric Genomics Consortium & Henderson, P., Sep 2013, In : Nature Genetics. 45, 9, p. 984-994 11 p.

Polygenic Risk and White Matter Integrity in Individuals at High Risk of Mood Disorder

Whalley, H. C., Sprooten, E., Hackett, S., Hall, L., Blackwood, D. H., Glahn, D. C., Bastin, M., Hall, J., Lawrie, S. M., Sussmann, J. E. & McIntosh, A. M., Aug 2013, In : Biological Psychiatry. 74, 4, p. 280-286

Neuroticism, depressive symptoms and white-matter integrity in the Lothian Birth Cohort 1936

McIntosh, A. M., Bastin, M. E., Luciano, M., Munoz-Maniega, S., Valdes Hernandez, M., Royle, N. A., Hall, J., Murray, C., Lawrie, S. M., Starr, J. M., Wardlaw, J. M. & Deary, I. J., Jun 2013, In : Psychological Medicine . 43, 6, p. 1197-1206 10 p.

Functional Imaging of Emotional Memory in Individuals at High Familial Risk of Bipolar Disorder with and without Depression

Whalley, H. C., Sussmann, J. E., Romaniuk, L., Hall, J., Lawrie, S. M. & McIntosh, A. M., 1 May 2013, In : Biological Psychiatry. 73, 9, p. 256S-256S 1 p.

White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder

Sprooten, E., Fleming, K. M., Thomson, P. A., Bastin, M. E., Whalley, H. C., Hall, J., Sussmann, J. E., McKirdy, J., Blackwood, D., Lawrie, S. M. & McIntosh, A. M., 30 Apr 2013, In : Psychiatry Research-Neuroimaging. 206, 2-3, p. 223-231 9 p.

A mega-analysis of genome-wide association studies for major depressive disorder

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Genetic schizophrenia risk variants jointly modulate total brain and white matter volume

Psychiatric Genome-wide association study (GWAS) Consortium, 15 Mar 2013, In : Biological Psychiatry. 73, 6, p. 525-531 7 p.

Prediction of Depression in Individuals at High Familial Risk of Mood Disorders Using Functional Magnetic Resonance Imaging

Whalley, H. C., Sussmann, J. E., Romaniuk, L., Stewart, T., Papmeyer, M., Sprooten, E., Hackett, S., Hall, J., Lawrie, S. M. & McIntosh, A. M., 6 Mar 2013, In : PLoS ONE. 8, 3, p. e57357

Cognitive endophenotypes in a family with bipolar disorder with a risk locus on chromosome 4

Drysdale, E., Knight, H. M., McIntosh, A. M. & Blackwood, D. H., Mar 2013, In : Bipolar Disorders. 15, 2, p. 215-222 8 p.

Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors

Andreassen, O. A., Djurovic, S., Thompson, W. K., Schork, A. J., Kendler, K. S., O'Donovan, M. C., Rujescu, D., Werge, T., van de Bunt, M., Morris, A. P., McCarthy, M. I., Roddey, J. C., McEvoy, L. K., Desikan, R. S., Dale, A. M., International Consortium for Blood Pressure GWAS & McIntosh, A., 7 Feb 2013, In : American Journal of Human Genetics. 92, 2, p. 197-209 13 p.

Is bipolar disorder more common in highly intelligent people? A cohort study of a million men

Gale, C. R., Batty, G. D., McIntosh, A. M., Porteous, D. J., Deary, I. J. & Rasmussen, F., Feb 2013, In : Molecular Psychiatry. 18, 2, p. 190-194 5 p.

The effect of long-term high frequency repetitive transcranial magnetic stimulation on working memory in schizophrenia and healthy controls-A randomized placebo-controlled, double-blind fMRI study

Guse, B., Falkai, P., Gruber, O., Whalley, H., Gibson, L., Hasan, A., Obst, K., Dechent, P., McIntosh, A., Suchan, B. & Wobrock, T., 15 Jan 2013, In : Behavioural Brain Research. 237, p. 300-307 8 p.

Toward a Systems Biology of Mood Disorder

McIntosh, A. M., 15 Jan 2013, In : Biological Psychiatry. 73, 2, p. 107-108 2 p.

Progress in imaging the effects of psychosis susceptibility gene variants

Redpath, H. L., Lawrie, S. M., Sprooten, E., Whalley, H. C., McIntosh, A. M. & Hall, J., Jan 2013, In : Expert review of neurotherapeutics. 13, 1, p. 37-47 11 p.

Polygenic Risk for Schizophrenia Is Associated with Cognitive Change Between Childhood and Old Age

McIntosh, A. M., Gow, A., Luciano, M., Davies, G., Liewald, D. C., Harris, S. E., Corley, J., Hall, J., Starr, J. M., Porteous, D. J., Tenesa, A., Visscher, P. M. & Deary, I. J., 2013, In : Biological Psychiatry. 73, 10, p. 938-943

An investigation of a genomewide supported psychosis variant in ZNF804A and white matter integrity in the human brain

Sprooten, E., McIntosh, A. M., Lawrie, S. M., Hall, J., Sussmann, J. E., Dahmen, N., Konrad, A., Bastin, M. E. & Winterer, G., Dec 2012, In : Magnetic Resonance Imaging. 30, 10, p. 1373-1380 8 p.

Predicting first episode psychosis in those at high risk for genetic or cognitive reasons

Lawrie, S. M., Stanfield, A., Johnstone, E. C. & McIntosh, A. M., Dec 2012, In : Epidemiology and psychiatric sciences. 21, 4, p. 323-328 6 p.

Impact of a microRNA MIR137 Susceptibility Variant on Brain Function in People at High Genetic Risk of Schizophrenia or Bipolar Disorder

Whalley, H., Papmeyer, M., Romaniuk, L., Sprooten, E., Johnstone, E. C., Hall, J., Lawrie, S. M., Evans, K. L., Blumberg, H. P., Sussmann, J. E. & McIntosh, A. M., Nov 2012, In : Neuropsychopharmacology. 37, 12, p. 2720-2729 10 p.

A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins

Eykelenboom, J. E., Briggs, G. J., Bradshaw, N. J., Soares, D. C., Ogawa, F., Christie, S., Malavasi, E. L. V., Makedonopoulou, P., Mackie, S., Malloy, M. P., Wear, M. A., Blackburn, E. A., Bramham, J., Mcintosh, A. M., Blackwood, D. H., Muir, W. J., Porteous, D. J. & Millar, J. K., 1 Aug 2012, In : Human Molecular Genetics. 21, 15, p. 3374-3386

Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: A polygenic risk score analysis

The Schizophrenia Psychiatric Genomic Consortium, 22 Jun 2012, In : PLoS ONE. 7, 6, e37852.

Activation During Angry Face Processing Differentiates Bipolar Relatives with Mood Disorders from those without

Sussmann, J., Whalley, H., Romaniuk, L., Stewart, T., Papmeyer, M., Sprooten, E., Lawrie, S. & McIntosh, A., 15 Apr 2012, In : Biological Psychiatry. 71, 8, p. 207S-207S 1 p.

Prediction of Mood Disorder in Those at Familial Risk using fMRI

Whalley, H. C., Sussmann, J. E., Romaniuk, L., Stewart, T., Papmeyer, M., Sprooten, E., Lawrie, S. M. & McIntosh, A. M., 15 Apr 2012, In : Biological Psychiatry. 71, 8, p. 207S-207S 1 p.

Runs of homozygosity implicate autozygosity as a schizophrenia risk factor

The Schizophrenia Psychiatric Genome-Wide Association Study Consortium, 1 Apr 2012, In : PLoS Genetics. 8, 4, e1002656.

Use of second-person pronouns and schizophrenia

Watson, A. R., Defterali, C., Bak, T. H., Sorace, A., McIntosh, A. M., Owens, D. G. C., Johnstone, E. C. & Lawrie, S. M., Apr 2012, In : The British Journal of Psychiatry. 200, 4, p. 342-3 2 p.

Grey matter differences in bipolar disorder: a meta-analysis of voxel-based morphometry studies

Selvaraj, S., Arnone, D., Job, D., Stanfield, A., Farrow, T. F., Nugent, A. C., Scherk, H., Gruber, O., Chen, X., Sachdev, P. S., Dickstein, D. P., Malhi, G. S., Ha, T. H., Ha, K., Phillips, M. L. & McIntosh, A. M., Mar 2012, In : Bipolar Disorders. 14, 2, p. 135-145 11 p.

Common and distinct neural correlates of emotional processing in Bipolar Disorder and Major Depressive Disorder: a voxel-based meta-analysis of functional magnetic resonance imaging studies

Delvecchio, G., Fossati, P., Boyer, P., Brambilla, P., Falkai, P., Gruber, O., Hietala, J., Lawrie, S. M., Martinot, J-L., McIntosh, A. M., Meisenzahl, E. & Frangou, S., Feb 2012, In : European Neuropsychopharmacology. 22, 2, p. 100-113 14 p.

Lower effective connectivity between amygdala and parietal regions in response to fearful faces in schizophrenia

Mukherjee, P., Whalley, H. C., McKirdy, J. W., McIntosh, A. M., Johnstone, E. C., Lawrie, S. M. & Hall, J., Feb 2012, In : Schizophrenia Research. 134, 2-3, p. 118-124 7 p.

Anterior cingulate morphology in people at genetic high-risk of schizophrenia

Meredith, S. M., Whyler, N. C. A., Stanfield, A. C., Chakirova, G., Moorhead, T. W. J., Job, D. E., Giles, S., McIntosh, A. M., Johnstone, E. C. & Lawrie, S. M., 2012, In : European Psychiatry.

Effect of variation in diacylglycerol kinase eta (DGKH) gene on brain function in a cohort at familial risk of bipolar disorder

Whalley, H., Papmeyer, M., Romaniuk, L., Johnstone, E. C., Hall, J., Lawrie, S. M., Sussmann, J. E. & McIntosh, A. M., 2012, In : Neuropsychopharmacology. 37, 4, p. 919-28 10 p.

Effects of a mis-sense DISC1 variant on brain activation in two cohorts at high risk of bipolar disorder or schizophrenia

Whalley, H. C., Sussmann, J. E., Johnstone, M., Romaniuk, L., Redpath, H., Chakirova, G., Mukherjee, P., Hall, J., Johnstone, E. C., Lawrie, S. M. & McIntosh, A. M., 2012, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 159B, 3, p. 343-53 11 p.

Genetic variation in Hyperpolarization-activated cyclic nucleotide-gated channels and its relationship with neuroticism, cognition and risk of depression

McIntosh, A. M., Simen, A. A., Evans, K. L., Hall, J., MacIntyre, D. J., Blackwood, D., Morris, A., Smith, B. H., Dominiczak, A., Porteous, D., Deary, I. & Thomson, P. A., 2012, In : Frontiers in genetics. 3, p. 116

Identification of common variants associated with human hippocampal and intracranial volumes

Stein, J. L., Medland, S. E., Vasquez, A. A., Hibar, D. P., Senstad, R. E., Winkler, A. M., Toro, R., Appel, K., Bartecek, R., Bergmann, O., Bernard, M., Brown, A. A., Cannon, D. M., Chakravarty, M. M., Christoforou, A., Domin, M., Grimm, O., Hollinshead, M., Holmes, A. J., Homuth, G. & 31 othersHottenga, J-J., Langan, C., Lopez, L. M., Hansell, N. K., Hwang, K. S., Kim, S., Laje, G., Lee, P. H., Liu, X., Loth, E., Lourdusamy, A., Mattingsdal, M., Mohnke, S., Maniega, S. M., Nho, K., Nugent, A. C., Davies, G., Lawrie, S. M., Liewald, D. C., Royle, N. A., Smith, C., Valdés Hernández, M. C., Hall, J., Porteous, D. J., Starr, J. M., Sussmann, J., Bastin, M. E., Deary, I. J., McIntosh, A. M., Wardlaw, J. M. & the Alzheimer's Disease Neuroimaging Initiative (ADNI), 2012, In : Nature Genetics. 44, 5, p. 552-561 10 p.

Magnetic resonance imaging studies in unipolar depression: systematic review and meta-regression analyses

Arnone, D., McIntosh, A. M., Ebmeier, K. P., Munafò, M. R. & Anderson, I. M., 2012, In : European Neuropsychopharmacology. 22, 1, p. 1-16 16 p.

Quantifying the RR of harm to self and others from substance misuse: results from a survey of clinical experts across Scotland

Taylor, M., Mackay, K., Murphy, J., McIntosh, A., McIntosh, C., Anderson, S. & Welch, K., 2012, In : BMJ Open. 2, 4

Review of functional magnetic resonance imaging studies comparing bipolar disorder and schizophrenia

Whalley, H. C., Papmeyer, M., Sprooten, E., Lawrie, S. M., Sussmann, J. E. & McIntosh, A. M., 2012, In : Bipolar Disorders. 14, 4, p. 411-31 21 p.

Social cognition, the male brain and the autism spectrum

Hall, J., Philip, R. C. M., Marwick, K., Whalley, H. C., Romaniuk, L., McIntosh, A. M., Santos, I., Sprengelmeyer, R., Johnstone, E. C., Stanfield, A. C., Young, A. W. & Lawrie, S. M., 2012, In : PLoS ONE. 7, 12, p. e49033

Tensor-based morphometry of cannabis use on brain structure in individuals at elevated genetic risk of schizophrenia

Welch, K. A., Moorhead, T. W., McIntosh, A. M., Owens, D. G. C., Johnstone, E. C. & Lawrie, S. M., 2012, In : Psychological Medicine . 43, 10, p. 2087-2096 10 p.

The association of genetic variation in CACNA1C with structure and function of a frontotemporal system

Wang, F., McIntosh, A. M., He, Y., Gelernter, J. & Blumberg, H. P., 2012, In : Bipolar Disorders. 13, 7-8, p. 696-700 5 p.

The functional neuroanatomy of bipolar disorder: a consensus model

Strakowski, S. M., Adler, C. M., Almeida, J., Altshuler, L. L., Blumberg, H. P., Chang, K. D., DelBello, M. P., Frangou, S., McIntosh, A., Phillips, M. L., Sussman, J. E. & Townsend, J. D., 2012, In : Bipolar Disorders. 14, 4, p. 313-25 13 p.

The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI

Whalley, H., Papmeyer, M., Sprooten, E., Romaniuk, L., Blackwood, D. H., Glahn, D. C., Hall, J., Lawrie, S. M., Sussmann, J. & McIntosh, A. M., 2012, In : Translational Psychiatry. 2, p. e130

Association of white matter integrity with genetic variation in an exonic DISC1 SNP

Sprooten, E., Sussmann, J. E., Moorhead, T. W., Whalley, H. C., Ffrench-Constant, C., Blumberg, H. P., Bastin, M. E., Hall, J., Lawrie, S. M. & McIntosh, A. M., Jul 2011, In : Molecular Psychiatry. 16, 7, p. 688-689

Longitudinal Volume Reductions in People at High Genetic Risk of Schizophrenia as They Develop Psychosis

McIntosh, A. M., Owens, D. C., Moorhead, W. J., Whalley, H. C., Stanfield, A. C., Hall, J., Johnstone, E. C. & Lawrie, S. M., 15 May 2011, In : Biological Psychiatry. 69, 10, p. 953-958 6 p.

The effects of DISC1 risk variants on brain activation in controls, patients with bipolar disorder and patients with schizophrenia

Chakirova, G., Whalley, H., Thomson, P. A., Hennah, W., Moorhead, T. W., Welch, K. A., Giles, S., Hall, J., Johnstone, E. C., Lawrie, S. M., Porteous, D. J., Brown, V. J. & McIntosh, A. M., 30 Apr 2011, In : Psychiatry Research. 192, 1, p. 20-28 9 p.

Structural magnetic resonance imaging in bipolar disorder: an international collaborative mega-analysis of individual adult patient data

Hallahan, B., Newell, J., Soares, J. C., Brambilla, P., Strakowski, S. M., Fleck, D. E., Kieseppä, T., Altshuler, L. L., Fornito, A., Malhi, G. S., McIntosh, A. M., Yurgelun-Todd, D. A., Labar, K. S., Sharma, V., MacQueen, G. M., Murray, R. M. & McDonald, C., 15 Feb 2011, In : Biological Psychiatry. 69, 4, p. 326-35 10 p.

Reduced white matter integrity in healthy individuals carrying the A-allele at DISC1 Ser704Cys

Sprooten, E., Sussmann, J. E., Moorhead, T. W., Whalley, H. C., Ffrench-Constant, C., Blumberg, H. P., Bastin, M. E., Hall, J., Lawrie, S. M. & McIntosh, A. M., 1 Jan 2011, In : Molecular Psychiatry. 16, 7, 1 p.

Are there progressive brain changes in schizophrenia? A meta-analysis of structural magnetic resonance imaging studies

Olabi, B., Ellison-Wright, I., McIntosh, A. M., Wood, S. J., Bullmore, E. & Lawrie, S. M., 2011, In : Biological Psychiatry. 70, 1, p. 88-96 9 p.

Association of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder

Kelmendi, B., Holsbach-Beltrame, M., McIntosh, A. M., Hilt, L., George, E. D., Kitchen, R. R., Carlyle, B. C., Pittenger, C., Coric, V., Nolen-Hoeksema, S., Sanacora, G. & Simen, A. A., 2011, In : Neuroscience Letters. 496, 3, p. 195-9 5 p.

DISC1 in schizophrenia: genetic mouse models and human genomic imaging

Johnstone, M., Thomson, P. A., Hall, J., McIntosh, A. M., Lawrie, S. M. & Porteous, D. J., 2011, In : Schizophrenia Bulletin. 37, 1, p. 14-20 7 p.

Do we have any solid evidence of clinical utility about the pathophysiology of schizophrenia?

Lawrie, S. M., Olabi, B., Hall, J. & McIntosh, A. M., 2011, In : World psychiatry : official journal of the World Psychiatric Association (WPA). 10, 1, p. 19-31 13 p.

Effects of the BDNF Val66Met polymorphism on neural responses to facial emotion

Mukherjee, P., Whalley, H. C., McKirdy, J. W., McIntosh, A. M., Johnstone, E. C., Lawrie, S. M. & Hall, J., 2011, In : Psychiatry Research. 191, 3, p. 182-8 7 p.

Genetic variants in the ErbB4 gene are associated with white matter integrity

Zuliani, R., Moorhead, T. W. J., Bastin, M. E., Johnstone, E. C., Lawrie, S. M., Brambilla, P., O'Donovan, M. C., Owen, M. J., Hall, J. & McIntosh, A. M., 2011, In : Psychiatry Research. 191, 2, p. 133-7 5 p.

Genetic variation in CNTNAP2 alters brain function during linguistic processing in healthy individuals

Whalley, H. C., O'Connell, G., Sussmann, J. E., Peel, A., Stanfield, A. C., Hayiou-Thomas, M. E., Johnstone, E. C., Lawrie, S. M., McIntosh, A. M. & Hall, J., 2011, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156B, 8, p. 941-8 8 p.

Genome-wide association study identifies five new schizophrenia loci

Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D-Y., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., St Clair, D., Corvin, A., Gurling, H., Werge, T., Rujescu, D., Blackwood, D. H. R., Pato, C. N., Malhotra, A. K. & 31 othersPurcell, S., Dudbridge, F., Neale, B. M., Rossin, L., Visscher, P. M., Posthuma, D., Ruderfer, D. M., Fanous, A., Stefansson, H., Steinberg, S., Mowry, B. J., Golimbet, V., De Hert, M., Jönsson, E. G., Bitter, I., Pietiläinen, O. P. H., Collier, D. A., Tosato, S., Agartz, I., Albus, M., Alexander, M., Amdur, R. L., Amin, F., Bass, N., Bergen, S. E., Black, D. W., Hansen, T., Maclean, A. W., McGhee, K. A., McIntosh, A. & Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, 2011, In : Nature Genetics. 43, 10, p. 969-76 8 p.

Impact of cannabis use on thalamic volume in people at familial high risk of schizophrenia

Welch, K. A., Stanfield, A. C., McIntosh, A. M., Whalley, H. C., Job, D. E., Moorhead, T. W., Owens, D. G. C., Lawrie, S. M. & Johnstone, E. C., 2011, In : The British Journal of Psychiatry. 199, 5, p. 386-90 5 p.

Prefrontal cortex gyrification index in twins: an MRI study

Hasan, A., McIntosh, A. M., Droese, U-A., Schneider-Axmann, T., Lawrie, S. M., Moorhead, T. W., Tepest, R., Maier, W., Falkai, P. & Wobrock, T., 2011, In : European archives of psychiatry and clinical neuroscience. 261, 7, p. 459-65 7 p.

Schizophrenia risk genes: Implications for future drug development and discovery

O'Connell, G., Lawrie, S. M., McIntosh, A. M. & Hall, J., 2011, In : Biochemical Pharmacology. 81, 12, p. 1367-73 7 p.

The impact of substance use on brain structure in people at high risk of developing schizophrenia

Welch, K. A., McIntosh, A. M., Job, D. E., Whalley, H., Moorhead, T. W., Hall, J., Owens, D. G. C., Lawrie, S. M. & Johnstone, E. C., 2011, In : Schizophrenia Bulletin. 37, 5, p. 1066-76 11 p.

The neural basis of familial risk and temperamental variation in individuals at high risk of bipolar disorder

Whalley, H., Sussmann, J. E., Chakirova, G., Mukerjee, P., Peel, A., McKirdy, J., Hall, J., Johnstone, E. C., Lawrie, S. M. & McIntosh, A. M., 2011, In : Biological Psychiatry. 70, 4, p. 343-349 7 p.

White matter integrity in individuals at high genetic risk of bipolar disorder

Sprooten, E., Sussmann, J. E., Clugston, A., Peel, A., McKirdy, J., Moorhead, T. W. J., Anderson, S., Shand, A. J., Giles, S., Bastin, M. E., Hall, J., Johnstone, E. C., Lawrie, S. M. & McIntosh, A. M., 2011, In : Biological Psychiatry. 70, 4, p. 350-356 7 p.

Effects of the BDNF val66met Polymorphism on Prefrontal Brain Function in a Population at High Genetic Risk of Schizophrenia

Whalley, H. C., Baig, B. J., Hall, J., Job, D. E., McIntosh, A. M., Cunningham-Owens, D. G., Johnstone, E. C. & Lawrie, S. M., Dec 2010, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 153B, 8, p. 1474-1482 9 p.

Midbrain Activation During Pavlovian Conditioning and Delusional Symptoms in Schizophrenia

Romaniuk, L., Honey, G. D., King, J. R. L., Whalley, H. C., McIntosh, A. M., Levita, L., Hughes, M., Johnstone, E. C., Day, M., Lawrie, S. M. & Hall, J., Dec 2010, In : Archives of General Psychiatry. 67, 12, p. 1246-1254 9 p.

The 'continuum of psychosis': scientifically unproven and clinically impractical

Lawrie, S. M., Hall, J., McIntosh, A. M., Owens, D. G. C. & Johnstone, E. C., Dec 2010, In : The British Journal of Psychiatry. 197, 6, p. 423-425 3 p.

Between- and within-scanner variability in the CaliBrain study n-back cognitive task

Gradin, V., Gountouna, V-E., Waiter, G., Ahearn, T. S., Brennan, D., Condon, B., Marshall, I., McGonigle, D. J., Murray, A. D., Whalley, H., Cavanagh, J., Hadley, D., Lymer, K., McIntosh, A., Moorhead, T. W., Job, D., Wardlaw, J., Lawrie, S. M. & Steele, J. D., 30 Nov 2010, In : Psychiatry Research-Neuroimaging. 184, 2, p. 86-95 10 p.

Orbitofrontal morphology in people at high risk of developing schizophrenia

Chakirova, G., Welch, K. A., Moorhead, T. W. J., Stanfield, A. C., Hall, J., Skehel, P., Brown, V. J., Johnstone, E. C., Owens, D. G. C., Lawrie, S. M. & McIntosh, A. M., Oct 2010, In : European Psychiatry. 25, 6, p. 366-372 7 p.

Functional magnetic resonance imaging of BDNF val66met polymorphism in unmedicated subjects at high genetic risk of schizophrenia performing a verbal memory task

Baig, B. J., Whalley, H. C., Hall, J., McIntosh, A. M., Job, D. E., Cunningham-Owens, D. G., Johnstone, E. C. & Lawrie, S. M., 30 Sep 2010, In : Psychiatry Research-Neuroimaging. 183, 3, p. 195-201 7 p.

Reduced prefrontal gyrification in obsessive-compulsive disorder

Wobrock, T., Gruber, O., McIntosh, A. M., Kraft, S., Klinghardt, A., Scherk, H., Reith, W., Schneider-Axmann, T., Lawrie, S. M., Falkai, P. & Moorhead, T. W., Sep 2010, In : European archives of psychiatry and clinical neuroscience. 260, 6, p. 455-464 10 p.

ARE THERE PROGRESSIVE BRAIN CHANGES IN SCHIZOPHRENIA? A SYSTEMATIC REVIEW AND META-ANALYSIS OF STRUCTURAL MAGNETIC RESONANCE IMAGING STUDIE

Olabi, B., Ellison-Wright, N. V., McIntosh, A. M., Wood, S. J., Bullmore, E. & Lawrie, S. M., Aug 2010, In : Journal of Psychopharmacology. 24, p. A86-A86 1 p.

Hippocampal and amygdala volumes in borderline personality disorder: A meta-analysis of magnetic resonance imaging studies

Hall, J., Olabi, B., Lawrie, S. M. & Mcintosh, A. M., Aug 2010, In : Personality and Mental Health. 4, 3, p. 172-179 8 p.

A common neural system mediating two different forms of social judgement

Hall, J., Whalley, H. C., McKirdy, J. W., Sprengelmeyer, R., Santos, I. M., Donaldson, D. I., McGonigle, D. J., Young, A. W., McIntosh, A. M., Johnstone, E. C. & Lawrie, S. M., Jul 2010, In : Psychological Medicine . 40, 7, p. 1183-1192 10 p.

Imaging the Mechanisms Underlying Vulnerability to Bipolar Disorder

McIntosh, A. M., 1 May 2010, In : Biological Psychiatry. 67, 9, p. 143S-143S 1 p.

Structural and Functional Brain Abnormalities in People at High Risk of Bipolar Disorder for Familial Reasons

McIntosh, A. M., 1 May 2010, In : Biological Psychiatry. 67, 9, p. 15S-15S 1 p.

Hippocampal function in schizophrenia and bipolar disorder

Hall, J., Lawrie, S. M., McIntosh, A. M., Johnstone, E. C., Romaniuk, L., Sussmann, J., Wan, H. I., McKirdy, J., Hall, J., Whalley, H. C. & Marwick, K., May 2010, In : Psychological Medicine . 40, 5, p. 761-770 10 p.

NEUROIMAGING AND COGNITION

McIntosh, A., Apr 2010, In : Schizophrenia Research. 117, 2-3, p. 128-128 1 p.

Functional Magnetic Resonance Imaging (fMRI) reproducibility and variance components across visits and scanning sites with a finger tapping task

Gountouna, V. E., Job, D. E., McIntosh, A. M., Moorhead, T. W. J., Lymer, G. K. L., Whalley, H. C., Hall, J., Waiter, G. D., Brennan, D., McGonigle, D. J., Ahearn, T. S., Cavanagh, J., Condon, B., Hadley, D. M., Marshall, I., Murray, A. D., Steele, J. D., Wardlaw, J. M. & Lawrie, S. M., Jan 2010, In : NeuroImage. 49, 1, p. 552-560 9 p.

Functional imaging of emotional memory in bipolar disorder and schizophrenia

Whalley, H., McKirdy, J., Romaniuk, L., Sussmann, J., Johnstone, E. C., Wan, H. I., McIntosh, A. M., Lawrie, S. M. & Hall, J., Dec 2009, In : Bipolar Disorders. 11, 8, p. 840-856 17 p.

Meta-analysis of magnetic resonance imaging studies in chromosome 22q11.2 deletion syndrome (velocardiofacial syndrome)

Tan, G. M., Arnone, D., McIntosh, A. M. & Ebmeier, K. P., Dec 2009, In : Schizophrenia Research. 115, 2-3, p. 173-181 9 p.

Progressive temporal lobe grey matter loss in adolescents with schizotypal traits and mild intellectual impairment

Moorhead, T. W. J., Stanfield, A., Spencer, M., Hall, J., McIntosh, A., Owens, D. C., Lawrie, S. & Johnstone, E., 30 Nov 2009, In : Psychiatry Research-Neuroimaging. 174, 2, p. 105-109 5 p.

Specific cognitive deficits in a group at genetic high risk of schizophrenia

O'Connor, M., Harris, J. M., McIntosh, A. M., Owens, D. G. C., Lawrie, S. M. & Johnstone, E. C., Oct 2009, In : Psychological Medicine . 39, 10, p. 1649-1655 7 p.

Genetic variation in the G72 (DAOA) gene affects temporal lobe and amygdala structure in subjects affected by bipolar disorder

Zuliani, R., Moorhead, B., Job, D., McKirdy, J., Sussmann, J. E. D., Johnstone, E. C., Lawrie, S. M., Brambilla, P., Hall, J. & McIntosh, A. M., Sep 2009, In : Bipolar Disorders. 11, 6, p. 621-627 7 p.

Magnetic resonance imaging studies in bipolar disorder and schizophrenia: meta-analysis

Arnone, D., Cavanagh, J., Gerber, D., Lawrie, S. M., Ebmeier, K. P. & McIntosh, A. M., Sep 2009, In : The British Journal of Psychiatry. 195, 3, p. 194-201 8 p.

Meta-analysis of region of interest studies in unipolar depression and bipolar disorder

Arnone, D., McIntosh, A. M., Ebmeier, K. P. & Anderson, I. M., Sep 2009, In : European Neuropsychopharmacology. 19, p. S375-S375 1 p.

Changes in Gyrification Over 4 Years in Bipolar Disorder and Their Association with the Brain-Derived Neurotrophic Factor Valine(66) Methionine Variant

Mirakhur, A., Moorhead, T. W. J., Stanfield, A. C., McKirdy, J., Sussmann, J. E. D., Hall, J., Lawrie, S. M., Johnstone, E. C. & McIntosh, A. M., 1 Aug 2009, In : Biological Psychiatry. 66, 3, p. 293-297 5 p.

Connecting the brain and new drug targets for schizophrenia

Whalley, H. C., Steele, J. D., Mukherjee, P., Romaniuk, L., McIntosh, A. M., Hall, J. & Lawrie, S. M., 1 Aug 2009, In : Current Pharmaceutical Design. 15, 22, p. 2615-2631 17 p.

Set shifting and reversal learning in patients with bipolar disorder or schizophrenia

McKirdy, J., Sussmann, J. E. D., Hall, J., Lawrie, S. M., Johnstone, E. C. & McIntosh, A. M., 1 Aug 2009, In : Psychological Medicine . 39, 8, p. 1289-1293 5 p.

fMRI changes over time and reproducibility in unmedicated subjects at high genetic risk of schizophrenia

Whalley, H. C., Gountouna, V-E., Hall, J., McIntosh, A. M., Simonotto, E., Job, D. E., Owens, D. G. C., Johnstone, E. C. & Lawrie, S. M., 1 Jul 2009, In : Psychological Medicine . 39, 7, p. 1189-1199 11 p.

Associative learning and the genetics of schizophrenia

Hall, J., Romaniuk, L., McIntosh, A. M., Steele, J. D., Johnstone, E. C. & Lawrie, S. M., Jun 2009, In : Trends in Neurosciences. 32, 6, p. 359-365 7 p.

Structural MRI in bipolar disorder: An international collaborative mega-analysis of individual patient data

Hallahan, B., Newell, J., Soares, J. C., Brambilla, P., Strakowski, S. M., Fleck, D. E., Kieseppa, T., Altshuler, L. L., Fornito, A., Malhi, G. S., McIntosh, A. M., Yurgelun-Todd, D. A., LaBar, K. S., Densmore, M., MacQueen, G. M., Murray, R. M. & McDonald, C., Jun 2009, In : Bipolar Disorders. 11, p. 10-11 2 p.

Working memory in schizophrenia: a meta-analysis

Forbes, N. F., Carrick, L. A., McIntosh, A. M. & Lawrie, S. M., Jun 2009, In : Psychological Medicine . 39, 6, p. 889-905 17 p.

A GRIK4 variant conferring protection against bipolar disorder modulates hippocampal function

Whalley, H., Pickard, B. S., McIntosh, A. M., Zuliani, R., Johnstone, E. C., Blackwood, D. H. R., Lawrie, S. M., Muir, W. J. & Hall, J., May 2009, In : Molecular Psychiatry. 14, 5, p. 467-468 2 p.

Fronto-Temporal Connectivity in Bipolar Disorder and Schizophrenia Related to Auditory Verbal Hallucinations

Sprooten, E., Romaniuk, L., Giles, S., Job, D. E., Mukherjee, P., Whalley, H. C., Lawrie, S. M., Johnstone, E. C., van de Ven, V. G. & McIntosh, A. M., 15 Apr 2009, In : Biological Psychiatry. 65, 8, p. 131S-131S 1 p.

Grey Matter Endophenotypes in Bipolar Disorder

McIntosh, A. M., 15 Apr 2009, In : Biological Psychiatry. 65, 8, p. 94S-94S 1 p.

Susceptibility Gene Variants for Schizophrenia and Bipolar Disorder Associated with Disrupted Functional and Structural Connectivity

McIntosh, A. M., 15 Apr 2009, In : Biological Psychiatry. 65, 8, p. 14S-14S 1 p.

The Relationship of Anterior Thalamic Radiation Integrity to Psychosis Risk Associated Neuregulin-1 Variants

Sprooten, E., Lymer, G. K., Maniega, S. M., McKirdy, J., Clayden, J. D., Bastin, M. E., Porteous, D., Johnstone, E. C., Lawrie, S. M., Hall, J. & McIntosh, A. M., 15 Apr 2009, In : Biological Psychiatry. 65, 8, p. 202S-203S 2 p.

Segmentation of the anterior thalamic radiation using neighbourhood tractography

Sprooten, E., Lymer, G. K. S., Maniega, S. M., McKirdy, J., Sussmann, J. E. D., Clayden, J. D., Bastin, M. E., Porteous, D., Johnstone, E. C., Lawrie, S. M., Hall, J. & McIntosh, A. M., 1 Mar 2009, In : Molecular Psychiatry. 14, 3, 1 p.

ENDOPHENOTYPES FOR SCHIZOPHRENIA AND BIPOLAR DISORDER DETERMINED USING BRAIN IMAGING

McIntosh, A. M., Hall, J. & Lawrie, S. M., Mar 2009, In : Schizophrenia Bulletin. 35, p. 218-218 1 p.

Obstetric complications and mild to moderate intellectual disability

Sussmann, J. E., McIntosh, A. M., Lawrie, S. M. & Johnstone, E. C., Mar 2009, In : The British Journal of Psychiatry. 194, 3, p. 224-228 5 p.

Prefrontal gyral folding and its cognitive correlates in bipolar disorder and schizophrenia

McIntosh, A. M., Moorhead, T. W. J., McKirdy, J., Hall, J., Sussmann, J. E. D., Stanfield, A. C., Harris, J. M., Johnstone, E. C. & Lawrie, S. M., Mar 2009, In : Acta psychiatrica scandinavica. 119, 3, p. 192-198 7 p.

Structural abnormalities of ventrolateral and orbitofrontal cortex in patients with familial bipolar disorder

Stanfield, A. C., Moorhead, T. W. J., Job, D. E., McKirdy, J., Sussmann, J. E. D., Hall, J., Giles, S., Johnstone, E. C., Lawrie, S. M. & McIntosh, A. M., Mar 2009, In : Bipolar Disorders. 11, 2, p. 135-144 10 p.

The relationship of anterior thalamic radiation integrity to psychosis risk associated neuregulin-1 variants

Sprooten, E., Lymer, G. K., Maniega, S. M., McKirdy, J., Clayden, J. D., Bastin, M. E., Porteous, D., Johnstone, E. C., Lawrie, S. M., Hall, J. & McIntosh, A. M., Mar 2009, In : Molecular Psychiatry. 14, 3, p. 237-238 2 p.

WHITE MATTER DISRUPTION IN INDIVIDUALS WITH PSYCHOSIS AND THOSE AT HIGH FAMILIAL RISK DETERMIEND BY SPECIFIC GENETIC VARIANTS

McIntosh, A. M., Sprooten, E., Zuliani, R., Sussmann, J., Hall, J. & Lawrie, S., Mar 2009, In : Schizophrenia Bulletin. 35, p. 209-209 1 p.

White matter abnormalities in bipolar disorder and schizophrenia detected using diffusion tensor magnetic resonance imaging

Sussmann, J. E., Lymer, G. K. S., McKirdy, J., Moorhead, T. W. J., Munoz-Maniega, S., Job, D., Hall, J., Bastin, M. E., Johnstone, E. C., Lawrie, S. M. & McIntosh, A. M., Feb 2009, In : Bipolar Disorders. 11, 1, p. 11-18 8 p.

Cortical thickness in a cohort of individuals at high genetic risk of schizophrenia.

Tijms, B. M., Moorhead, T. W., Whalley, H. C., Job, D. E., Willshaw, D. J., McIntosh, A. M., Johnstone, E. C. & Lawrie, S. M., 2009, In : NeuroImage. 47, Supplement 1, 0, p. S121 -

Genetic risk for white matter abnormalities in bipolar disorder

Mcintosh, A. M., Hall, J., Lymer, G. K. S., Sussmann, J. E. D. & Lawrie, S. M., 2009, In : International Review of Psychiatry. 21, 4, p. 387-393 7 p.

Modulation of hippocampal activation by genetic variation in the GRIK4 gene

Whalley, H. C., Pickard, B. S., McIntosh, A. M., Zuliani, R., Johnstone, E. C., Blackwood, D. H. R., Lawrie, S. M., Muir, W. J. & Hall, J., 2009, In : Molecular Psychiatry. 14, 5, p. 465

Prospective multi-centre Voxel Based Morphometry study employing scanner specific segmentations: procedure development using CaliBrain structural MRI data

Moorhead, T. W. J., Gountouna, V-E., Job, D. E., McIntosh, A. M., Romaniuk, L., Lymer, G. K. S., Whalley, H. C., Waiter, G. D., Brennan, D., Ahearn, T. S., Cavanagh, J., Condon, B., Steele, J. D., Wardlaw, J. M. & Lawrie, S. M., 2009, In : BMC medical imaging. 9, p. 8

White Matter Tractography in Bipolar Disorder and Schizophrenia

McIntosh, A. M., Maniega, S. M., Lymer, G. K. S., McKirdy, J., Hall, J., Sussmann, J. E. D., Bastin, M. E., Clayden, J. D., Johnstone, E. C. & Lawrie, S. M., 15 Dec 2008, In : Biological Psychiatry. 64, 12, p. 1088-1092 5 p.

A diffusion tensor MRI study of white matter integrity in subjects at high genetic risk of schizophrenia

Munoz Maniega, S., Lymer, G. K., Bastin, M. E., Marjoram, D., Job, D. E., Moorhead, T. W., Owens, D. G., Johnstone, E. C., McIntosh, A. M. & Lawrie, S. M., Dec 2008, In : Schizophrenia Research. 106, 2-3, p. 132-139 8 p.

Meta-analysis of magnetic resonance imaging studies of the corpus callosum in bipolar disorder

Arnone, D., McIntosh, A. M., Chandra, P. & Ebmeier, K. P., Nov 2008, In : Acta psychiatrica scandinavica. 118, 5, p. 357-362 6 p.

Meta-analysis of magnetic resonance imaging studies of the corpus callosum in bipolar disorder

Arnone, D., McIntosh, A. M., Chandra, P. & Ebmeier, K. P., Nov 2008, In : Acta psychiatrica scandinavica. 118, 5, p. 357-62 6 p.

The effects of a neuregulin 1 variant on white matter density and integrity

McIntosh, A. M., Moorhead, T. W., Job, D., Lymer, G. K., Munoz Maniega, S., McKirdy, J., Sussmann, J. E., Baig, B., Bastin, M. E., Porteous, D., Evans, K. L., Johnstone, E. C., Lawrie, S. M. & Hall, J., Nov 2008, In : Molecular Psychiatry. 13, 11, p. 1054-1059 6 p.

Genetic variation in the DAOA (G72) gene modulates hippocampal function in subjects at high risk of schizophrenia

Hall, J., Whalley, H., Moorhead, T. W. J., Baig, B. J., McIntosh, A. M., Job, D. E., Owens, D. G. C., Lawrie, S. M. & Johnstone, E. C., 1 Sep 2008, In : Biological Psychiatry. 64, 5, p. 428-433 6 p.

The rate of usage of electroconvulsive therapy in the city of Edinburgh, 1993-2005

Okagbue, N., McIntosh, A., Gardner, M. & Scott, A. I. F., 1 Sep 2008, In : Journal of ect. 24, 3, p. 229-231 3 p.

Overactivation of fear systems to neutral faces in schizophrenia

Hall, J., Whalley, H. C., McKirdy, J. W., Romaniuk, L., McGonigle, D., McIntosh, A. M., Baig, B. J., Gountouna, V-E., Job, D. E., Donaldson, D. I., Sprengelmeyer, R., Young, A. W., Johnstone, E. C. & Lawrie, S. M., 1 Jul 2008, In : Biological Psychiatry. 64, 1, p. 70-73 4 p.

Structural and functional neuroimaging studies of schizophrenia and bipolar disorder

Hall, J., Sussmann, J., Moorehead, W., Whalley, H., Johnstone, E. C., Lawrie, S. & McIntosh, A., 1 Apr 2008, In : Biological Psychiatry. 63, 7, p. 156S-156S 1 p.

A Neuregulin 1 variant associated with altered brain structure and function

McIntosh, A. M., Apr 2008, In : European Psychiatry. 23, p. S18-S18 1 p.

Evidence of shared white matter disruption in bipolar disorder and sschizophrenia

McIntosh, A. M., Sussmann, J., Lymer, G. K. S., Munoz-Maniega, S., Bastin, M., Hall, J., Lawrie, S., Johnstone, E., Clayden, J., Job, D. & Moorhead, T. W. J., Apr 2008, In : European Psychiatry. 23, p. S43-S43 1 p.

Meta-analysis of magnetic resonance imaging studies of the corpus callosum in bipolar disorder

Arnone, D., McIntosh, A. M., Chandra, P. & Ebmeier, K. P., Apr 2008, In : European Psychiatry. 23, p. S225-S225 1 p.

Meta-analysis of magnetic resonance imaging studies of the corpus callosum in schizophrenia

Arnone, D., McIntosh, A. M., Tan, G. M. Y. & Ebmeier, K. P., Apr 2008, In : Schizophrenia Research. 101, 1-3, p. 124-132 9 p.

Brain structure and function changes during the development of schizophrenia: The evidence from studies of subjects at increased genetic risk

Lawrie, S. M., McIntosh, A. M., Hall, J., Owens, D. G. C. & Johnstone, E. C., Mar 2008, In : Schizophrenia Bulletin. 34, 2, p. 330-340 11 p.

Neuroimaging and molecular genetics of schizophrenia: pathophysiological advances and therapeutic potential

Lawrie, S. M., Hall, J., McIntosh, A. M., Cunningham-Owens, D. G. & Johnstone, E. C., Mar 2008, In : British Journal of Pharmacology. 153, p. S120-S124 5 p.

Low birthweight and preterm birth in young people with special educational needs: a magnetic resonance imaging analysis

Spencer, M. D., Moorhead, B., Gibson, R. J., McIntosh, A. M., Sussmann, J. E. D., Owens, D. G. C., Lawrie, S. M. & Johnstone, E. C., 30 Jan 2008, In : BMC Medicine. 6, 1, p. - 11 p., 1.

Hypofrontality in subjects at high genetic risk of schizophrenia with depressive symptoms

Whalley, H. C., Mowatt, L., Stanfield, A. C., Hall, J., Johnstone, E. C., Lawrie, S. M. & McIntosh, A. M., 2008, In : Journal of affective disorders. 109, 1-2, p. 99-106 8 p.

Prefrontal function and activation in bipolar disorder and schizophrenia

McIntosh, A. M., Whalley, H. C., McKirdy, J., Hall, J., Sussmann, J. E. D., Shankar, P., Johnstone, E. C. & Lawrie, S. M., 2008, In : American Journal of Psychiatry. 165, 3, p. 378-384 7 p.

Towards a neuroanatomy of autism: a systematic review and meta-analysis of structural magnetic resonance imaging studies

Stanfield, A. C., McIntosh, A. M., Spencer, M. D., Phillip, R., Gaur, S. & Lawrie, S. M., 2008, In : European Psychiatry. 23, 4, p. 289-299 11 p.

Increased prefrontal gyrification in a large high-risk cohort characterizes those who develop schizophrenia and reflects abnormal prefrontal development

Harris, J. M., Moorhead, T. W. J., Miller, P., McIntosh, A. M., Bonnici, H. M., Owens, D. G. C., Johnstone, E. C. & Lawrie, S. M., 1 Oct 2007, In : Biological Psychiatry. 62, 7, p. 722-9 8 p.

Relationship of catechol-O-methyltransferase variants to brain structure and function in a population at high risk of psychosis

McIntosh, A. M., Baig, B. J., Hall, J., Job, D., Whalley, H. C., Lymer, G. K. S., Moorhead, T. W. J., Owens, D. G. C., Miller, P., Porteous, D., Lawrie, S. M. & Johnstone, E. C., 15 May 2007, In : Biological Psychiatry. 61, 10, p. 1127-1134 8 p.

Correlations between fMRI activation and individual psychotic symptoms in un-medicated subjects at high genetic risk of schizophrenia

Whalley, H. C., Gountouna, V-E., Hall, J., McIntosh, A., Whyte, M-C., Simonotto, E., Job, D. E., Owens, D. G. C., Johnstone, E. C. & Lawrie, S. M., 2007, In : BMC Psychiatry. 7, 10 p., 61.

Grey matter correlates of early psychotic symptoms in adolescents at enhanced risk of psychosis: a voxel-based study

Spencer, M. D., Moorhead, T. W. J., McIntosh, A. M., Stanfield, A. C., Muir, W. J., Hoare, P., Owens, D. G. C., Lawrie, S. M. & Johnstone, E. C., 2007, In : NeuroImage. 35, 3, p. 1181-91 11 p.

Progressive gray matter loss in patients with bipolar disorder

Moorhead, T. W. J., McKirdy, J., Sussmann, J. E. D., Hall, J., Lawrie, S. M., Johnstone, E. C. & McIntosh, A. M., 2007, In : Biological Psychiatry. 62, 8, p. 894-900 7 p.

Temporal grey matter reductions in bipolar disorder are associated with the BDNF Val66Met polymorphism

McIntosh, A. M., Moorhead, T. W. J., McKirdy, J., Sussmann, J. E. D., Hall, J., Johnstone, E. C. & Lawrie, S. M., 2007, In : Molecular Psychiatry. 12, 10, p. 902-3 2 p.

The challenges of developing a collaborative data and compute grid for neurosciences

Geddes, J., Mackay, C., Lloyd, S., Simpson, A., Power, D., Russell, D., Katzarova, M., Rossor, M., Fox, N., Fletcher, J., Hill, D., McLeish, K., Hajnal, J. V., Lawrie, S., Job, D., McIntosh, A., Wardlaw, J., Sandercock, P., Palmer, J., Perry, D. & 4 othersProcter, R., Ure, J., Bath, P. & Watson, G., 22 Dec 2006, Proceedings - 19th IEEE International Symposium on Computer-Based Medical Systems, CBMS 2006. Vol. 2006. p. 81-86 6 p. 1647550

Grey matter changes can improve the prediction of schizophrenia in subjects at high risk

Job, D. E., Whalley, H. C., McIntosh, A. M., Owens, D. G. C., Johnstone, E. C. & Lawrie, S. M., 7 Dec 2006, In : BMC Medicine. 4, 4 p., 29.

Brain-behaviour relationships in people at high genetic risk of schizophrenia

Lymer, G. K. S., Job, D. E., William, T., Moorhead, J., McIntosh, A. M., Owens, D. G. C., Johnstone, E. C. & Lawrie, S. M., 15 Oct 2006, In : NeuroImage. 33, 1, p. 275-85 11 p.

A neuropsychological investigation into 'Theory of Mind' and enhanced risk of schizophrenia

Marjoram, D., Miller, P., McIntosh, A. M., Cunningham Owens, D. G., Johnstone, E. C. & Lawrie, S., 30 Sep 2006, In : Psychiatry Research. 144, 1, p. 29-37 9 p.

Functional imaging as a predictor of schizophrenia

Whalley, H. C., Simonotto, E., Moorhead, W., McIntosh, A., Marshall, I., Ebmeier, K. P., Owens, D. G. C., Goddard, N. H., Johnstone, E. C. & Lawrie, S. M., 1 Sep 2006, In : Biological Psychiatry. 60, 5, p. 454-62 9 p.

A visual joke fMRI investigation into Theory of Mind and enhanced risk of schizophrenia

Marjoram, D., Job, D. E., Whalley, H. C., Gountouna, V-E., McIntosh, A. M., Simonotto, E., Cunningham-Owens, D., Johnstone, E. C. & Lawrie, S., 15 Jul 2006, In : NeuroImage. 31, 4, p. 1850-1858 9 p.

Support workers' attitudes to mental illness: Implications for reducing stigma

Tipper, R., Mountain, D., Lorimer, S. & McIntosh, A., 1 May 2006, In : Psychiatric Bulletin. 30, 5, p. 179-181 3 p.

Genetic liability to schizophrenia or bipolar disorder and its relationship to brain structure

McIntosh, A. M., Job, D. E., Moorhead, W. J., Harrison, L. K., Whalley, H. C., Johnstone, E. C. & Lawrie, S. M., 5 Jan 2006, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 141B, 1, p. 76-83 8 p.

A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms

Hall, J., Whalley, H. C., Job, D. E., Baig, B. J., McIntosh, A. M., Evans, K. L., Thomson, P. A., Porteous, D. J., Cunningham-Owens, D. G., Johnstone, E. C. & Lawrie, S. M., 2006, In : Nature Neuroscience. 9, 12, p. 1477-1478 2 p.

Compliance therapy for schizophrenia

McIntosh, A. M., Conlon, L., Lawrie, S. M. & Stanfield, A. C., 2006, In : Cochrane database of systematic reviews. 3, p. CD003442

Designing for e-Health: recurring scenarios in developing grid-based medical imaging systems

Geddes, J., Mackay, C., Lloyd, S., Simpson, A., Power, D., Russell, D., Jirotka, M., Katzarova, M., Rossor, M., Fox, N., Fletcher, J., Hill, D., McLeish, K., Chen, Y., Hajnal, J. V., Lawrie, S., Job, D., McIntosh, A., Wardlaw, J., Sandercock, P. & 11 othersPalmer, J., Perry, D., Procter, R., Ure, J., Hartswood, M., Slack, R., Voss, A., Ho, K., Bath, P., Clarke, W. & Watson, G., 2006, In : Stud Health Technol Inform. 120, p. 336-47 12 p.

Relationship of COMT variants to brain structure, function and risk of psychosis

McIntosh, A. M., Baig, B., Hall, J., Job, D., Whalley, H. C., Owens, D., Miller, P., Porteous, D., Lawrie, S. M. & Johnstone, E. C., 2006, In : Schizophrenia Research. 81, p. 192-193 2 p.

Declarative memory in unaffected adult relatives of patients with schizophrenia: a systematic review and meta-analysis

Whyte, M-C., McIntosh, A. M., Johnstone, E. C. & Lawrie, S. M., 1 Oct 2005, In : Schizophrenia Research. 78, 1, p. 13-26 14 p.

White matter density in patients with schizophrenia, bipolar disorder and their unaffected relatives

McIntosh, A. M., Job, D. E., Moorhead, T. W. J., Harrison, L. K., Lawrie, S. M. & Johnstone, E. C., 1 Aug 2005, In : Biological Psychiatry. 58, 3, p. 254-7 4 p.

Neuropsychological impairments in people with schizophrenia or bipolar disorder and their unaffected relatives

McIntosh, A. M., Harrison, L. K., Forrester, K., Lawrie, S. M. & Johnstone, E. C., May 2005, In : The British Journal of Psychiatry. 186, p. 378-85 8 p.

Cannabis as a risk factor for psychosis: systematic review

Semple, D. M., McIntosh, A. M. & Lawrie, S. M., Mar 2005, In : Journal of Psychopharmacology. 19, 2, p. 187-94 8 p.

Voxel-based morphometry of patients with schizophrenia or bipolar disorder and their unaffected relatives

McIntosh, A. M., Job, D. E., Moorhead, T. W. J., Harrison, L. K., Forrester, K., Lawrie, S. M. & Johnstone, E. C., 15 Oct 2004, In : Biological Psychiatry. 56, 8, p. 544-552 9 p.

Transcranial magnetic stimulation for auditory hallucinations in schizophrenia

McIntosh, A. M., Semple, D., Tasker, K., Harrison, L. K., Owens, D. G. C., Johnstone, E. C. & Ebmeier, K. P., 30 Jun 2004, In : Psychiatry Research. 127, 1-2, p. 9-17 9 p.

Patterns of grey matter loss discriminate between schizophrenia and bipolar disorder

McIntosh, AM., Job, D., Harrison, LK., Forrester, K., Moorhead, TW. & Johnstone, EC., 15 Feb 2004, In : Schizophrenia Research. 67, 1, p. 26-26 1 p.

Genetic liability, brain structure and symptoms of schizophrenia

McIntosh, A., Whalley, H., Job, D., Johnstone, E. & Lawrie, S., 2004, SEARCH FOR THE CAUSES OF THE SCHIZOPHRENIA, VOL 5. Gattaz, WF. & Hafner, H. (eds.). BERLIN 33: STEINKOPFF DARMSTADT, p. 161-181 21 p.

Patterns of grey matter density partially separate schizophrenia and bipolar disorder

McIntosh, A., Job, D., Moorhead, B., Harrison, L., Forrester, K., Lawrie, S. & Johnstone, E., 2004, In : Acta psychiatrica scandinavica. 110, p. 28-28 1 p.

Reduced binocular depth inversion in regular cannabis users

Semple, D. M., Ramsden, F. & McIntosh, A. M., Jul 2003, In : Pharmacology Biochemistry and Behavior. 75, 4, p. 789-93 5 p.

Maternal recall bias, obstetric history and schizophrenia

McIntosh, A. M., Holmes, S., Gleeson, S., Burns, J. K., Hodges, A. K., Byrne, M. M., Dobbie, R., Miller, P., Lawrie, S. M. & Johnstone, E. C., Dec 2002, In : The British Journal of Psychiatry. 181, p. 520-5 6 p.

Risperidone reduced the risk of relapse in outpatient schizophrenia and schizoaffective disorder

McIntosh, A. M., Aug 2002, In : Evidence-based mental health. 5, 3, p. 77

Invited commentaries on: Signs of asphyxia at birth and risk of schizophrenia/Obstetric complications and risk of schizophrenia

Crow, T. J., McIntosh, A. M. & Lawrie, S. M., Nov 2001, In : The British Journal of Psychiatry. 179, p. 415-6 2 p.

A factor model of the functional psychoses and the relationship of factors to clinical variables and brain morphology

McIntosh, A. M., Forrester, A., Lawrie, S. M., Byrne, M., Harper, A., Kestelman, J. N., Best, J. J., Johnstone, E. C. & Owens, D. G., Jan 2001, In : Psychological Medicine . 31, 1, p. 159-71 13 p.

Projects

2010 independent Investigator Award - Dr A McIntosh

McIntosh, A.

Non-EU-based charities

15/09/1014/09/12

A network for studying psychological resilience in low- and middle-income countries (NESP)

McIntosh, A., Ecks, S., Grant, L., Harper, I., Jain, S., Lawrie, S., Macbeth, A., Pagliari, C., Pickersgill, M. & Wolters, M.

MRC

1/03/1831/05/19

An iPS model of Bipolar Disorder based on a Large Family with a Highly Penetrant Mutation

McIntosh, A., Chandran, S. & Evans, K.

UK central government bodies/local authorities, health and hospital authorities

1/07/1231/12/16

Cash Contribution for BADiPS Project

McIntosh, A.

Other

1/10/1530/09/16

Clinical Validation of Eye Movement Abnormalities as diagnostic biomarkers of psychiatric Disorders

McIntosh, A.

UK industry, commerce and public corporations

16/03/1515/03/18

Developing an in-vitro model of psychosis through the study of identified genetic risk factors

McIntosh, A.

UK central government bodies/local authorities, health and hospital authorities

1/06/1231/08/13

Examining the relationship between depression and cognition using multiply affected pedigrees

McIntosh, A., Clarke, T. & Deary, I.

24/10/1424/10/17

Functional imaging biomarkers of cognitive enhancer efficacy

Lawrie, S., Hall, J. & McIntosh, A.

UK industry, commerce and public corporations

1/01/0731/03/09

Generation Malawi: A study of family, maternal and childhood mental health

McIntosh, A., Pickersgill, M. & Stewart, R.

MRC

1/05/1931/10/23

Genetic Variation in HCN1-4 and it's relationship to cognition and depression in individuals from the Generation Scotland: Scotrish Family Health Study

McIntosh, A., Deary, I., Evans, K., Hall, J. & Thomson, P.

UK central government bodies/local authorities, health and hospital authorities

1/01/1131/03/12

Grand Challenge: Brain Imaging Studies of Pre-Frontal Glutamate Concentration, Perfusion and Activity

Lawrie, S., Hall, J. & McIntosh, A.

UK industry, commerce and public corporations

1/09/1031/08/13

Grand Challenge: Brain imaging studies of pre-frontal glutatamate concentration, perfusion and activity

Lawrie, S., Hall, J. & McIntosh, A.

UK industry, commerce and public corporations

1/04/1131/08/13

IMAGEMEND: IMAGEMEND IMAging GEnetics for MENtal Disorders - Other and MGT

McIntosh, A.

EU government bodies

1/10/1330/09/17

IMAGEMEND: IMAGEMEND IMAging GEnetics for MENtal Disorders - RTD

McIntosh, A.

EU government bodies

1/10/1330/09/17

INVESTIGATION OF MICRO RNAS AS BIOMARKERS AND DRUG TARGETS FOR BIPOLAR DISORDER

Evans, K., McIntosh, A. & Porteous, D.

UK central government bodies/local authorities, health and hospital authorities

1/04/1230/09/14

Investigating the molecular and cellularconsequences of disrupted in Schizophrenia 1 in patient derived nueral stem cells

Porteous, D. & McIntosh, A.

UK-based charities

1/10/1230/09/16

Investigating the shared genetic basis of major depressive disorder (MDD) and type 2 diabetes (T2D).

Clarke, T. & McIntosh, A.

17/11/147/11/17

Leveraging routinely collected and linked research data to study the causes and consequences of common mental disorders

McIntosh, A., Crompton, C., Fletcher-Watson, S., Lawrie, S. & Sibley, H.

MRC

31/03/1830/03/20

Magnetic Resonance Imaging of Lifecourse Influences on Brain Health and Disease (Biomedical Resource/Multi-User Equipment/Technology Development Grant)

Wardlaw, J., Boardman, J., Marshall, I., McIntosh, A. & Salman, R.

UK-based charities

1/01/1531/12/19

Medical Research Scotland - Vacation Scholarship Application McLoughlin (McIntosh supervisor)

McIntosh, A.

UK-based charities

27/05/1922/07/19

Modelling psychosis using DISC1 human induced pluripotent stem cells

McIntosh, A. & Chandran, S.

MRC

1/06/1231/05/15

Neurocognitive abnormality in individuals at high risk of bipolar disorder or schizophrenia for genetic reasons.

McIntosh, A.

UK-based charities

15/09/0630/06/13

Pedigree-based whole genome sequencing of affective and psychotic disorders

McIntosh, A.

Non-EU other

1/03/1531/10/18

PreMDD: Predicting major depressive disorder

Porteous, D., Nicodemus, K., Agakov, F., McKeigue, P., Campbell, A., Bermingham, M., Munoz, D. U., McIntosh, A. & Marriage, H. M.

1/04/1530/09/15

Sample collection for the Stanley Center for Psychiatric Research

McIntosh, A.

Non-EU other

1/02/1031/12/13

Stratifying Depression using Genetic Information

McIntosh, A. & Clarke, T.

24/10/1424/10/17

Stratifying Resilience and Depression Longitudinally

McIntosh, A., Deary, I., Evans, K., Haley, C. & Porteous, D.

UK-based charities

1/01/1531/12/20

WHITE MATTER INTEGRITY IN BIPOLARSISORDER & SCHIZOPHRENIA

McIntosh, A., Hall, J., Johnstone, E., Lawrie, S. & Lymer, K.

UK central government bodies/local authorities, health and hospital authorities

1/07/0630/07/09

Press clippings

100 genes are linked to depression

Andrew McIntosh

5/02/196/02/19

17 media contributions

A study into the causes of clinical depression to receive £4.7 million in the hopes new treatments can be developed

Andrew McIntosh

12/05/14

12 items of media coverage

Andrew McIntosh & David Howard find nearly 80 genes that could be linked to depression

Andrew McIntosh, David Howard & David Howard

4/02/195/02/19

10 items of media coverage

Bipolar research by Prof Andrew McIntosh to benefit from sharing of patients’ stem cells

Andrew McIntosh

9/08/16

7 items of media coverage

Depression study led by Andrew McIntosh holds event to thank volunteer participants

Andrew McIntosh

31/05/17

1 item of media coverage

Dr Andrew McIntosh to study causes of depression with 20,000 study participants

Andrew McIntosh

16/06/15

2 items of media coverage

Edinburgh University researchers delvelop method of predicting schizophrenia

Andrew McIntosh

22/12/10

18 items of media coverage

Prof Andrew McIntosh comments on a study into chronic fatigue syndrome

Andrew McIntosh

30/08/16

2 items of media coverage

Prof Andrew McIntosh links chronic pain to partners of people with depression

Andrew McIntosh

17/08/16

13 items of media coverage

Prof Andrew McIntosh suggests depression may have origins in DNA

Andrew McIntosh

31/01/17

1 item of media coverage

Professor Andrew McIntosh discusses mood disorders and schizophrenia

Andrew McIntosh

27/02/12

1 item of media coverage

Professor Andrew McIntosh links genetic risk for schizophrenia to low IQ

Andrew McIntosh

16/05/13

9 items of media coverage

Professor Andrew McIntosh seeks to develop brain cells from skin

Andrew McIntosh

29/01/12

13 items of media coverage

Researchers find genes linked to schizophrenia can affect IQ in later life

Andrew McIntosh & Ian Deary

21/02/13

26 items of media coverage

£2.2m boost for pioneering research into mental health conditions

Andrew McIntosh

31/03/18

3 items of media coverage

£4.7m study, led by Prof Andrew McIntosh, seeks more effective ways to combat depression

Andrew McIntosh

3/07/14

1 item of media coverage