Edinburgh Research Explorer

Anna Williams

Personal chair of Regenerative neurology

  1. 'Small vessels, dementia and chronic diseases -molecular mechanisms and pathophysiology' Workshop proceedings

    Horsburgh, K., Wardlaw, J., Van Agtmael, T., Allan, S., Ashford, M., Bath, P. M., Brown, R., Berwick, J., Cader, M. Z., Carare, R. O., Davies, J. B., Duncombe, J., Farr, T. D., Fowler, J., Goense, J., Granata, A., Hall, C., Hainsworth, A., Harvey, A., Hawkes, C. & 26 others, Joutel, A., Kalaria, R. N., Kehoe, P. G., Lawrence, C. B., Lockhart, A., Love, S., MacLeod, M., Macrae, M., Markus, H. S., McCabe, C., McColl, B., Meakin, P. J., Miller, A. A., Nedergaard, M., O'Sullivan, M., Quinn, T., Rajani, R., Saksida, L. M., Smith, C., Smith, K. J., Touyz, R., Trueman, R., Wang, T., Williams, A., Williams, S. & Work, L. M., 30 Apr 2018, In : Clinical science. 132, 8, p. 851-868

    Research output: Contribution to journalReview article

  2. A mutation in periaxin is responsible for CMT4F, an autosomal recessive form of Charcot-Marie-Tooth disease

    Guilbot, A., Williams, A., Ravisé, N., Verny, C., Brice, A., Sherman, D. L., Brophy, P. J., LeGuern, E., Delague, V., Bareil, C., Mégarbané, A. & Claustres, M., 15 Feb 2001, In : Human Molecular Genetics. 10, 4, p. 415-21 7 p.

    Research output: Contribution to journalArticle

  3. Activin receptors regulate the oligodendrocyte lineage in health and disease

    Dillenburg, A., Ireland, G., Holloway, R. K., Davies, C. L., Evans, F. L., Swire, M., Bechler, M. E., Soong, D., Yuen, T. J., Su, G. H., Becher, J-C., Smith, C., Williams, A. & Miron, V. E., 3 Feb 2018, In : Acta Neuropathologica.

    Research output: Contribution to journalArticle

  4. Alkyne-tagged PLGA allows direct visualisation of nanoparticles in vitro and ex vivo by stimulated Raman scattering microscopy

    Vanden-hehir, S., Cairns, S. A., Lee, M., Zoupi, L., Shaver, M. P., Brunton, V. G., Williams, A. & Hulme, A. N., 13 Aug 2019, In : Biomacromolecules.

    Research output: Contribution to journalArticle

  5. Altered human oligodendrocyte heterogeneity in multiple sclerosis

    Jäkel, S., Agirre, E., Falcão, A. M., van Bruggen, D., Lee, K. W., Knuesel, I., Malhotra, D., ffrench-Constant, C., Williams, A. & Castelo-Branco, G., 23 Jan 2019, In : Nature. 566, p. 543–547

    Research output: Contribution to journalArticle

  6. Association between endothelial cell stabilizing medication and small vessel disease stroke: a case-control study

    Becker, C. E., Quinn, T. & Williams, A., 25 Sep 2019, In : Frontiers in Neurology.

    Research output: Contribution to journalArticle

  7. Biomass fuel flexibility in future conventional power generation

    Mason, P. E., Riaza, J., Chalmers, H., Darvell, L. I., Jones, J. M. & Williams, A., 1 Jan 2016.

    Research output: Contribution to conferencePaper

  8. CLAUDIN K IS SPECIFICALLY EXPRESSED IN MYELIN OF DEVELOPING AND ADULT ZEBRAFISH

    Muenzel, J., Schaefer, K., Obirei, B., Broesamle, C., Burton, E. A., Kuscha, V., Becker, C. G., Williams, A. & Becker, T., Oct 2011, In : Glia. 59, p. S63-S63 1 p.

    Research output: Contribution to journalMeeting abstract

  9. Calcitriol modulates the CD46 pathway by controlling its expression and function on T cells

    Kickler, K., Choileain, S. N., Williams, A., Richards, A. & Astier, A. L., Sep 2012, In : Immunology . 137, p. 469-469 1 p.

    Research output: Contribution to journalMeeting abstract

  10. Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis

    Nicaise, A. M., Wagstaff, L. J., Willis, C. M., Paisie, C., Chandok, H., Robson, P., Fossati, V., Williams, A. & Crocker, S. J., Apr 2019, In : Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalArticle

  11. Central nervous system regeneration is driven by microglia necroptosis and repopulation

    Lloyd, A. F., Davies, C. L., Holloway, R. K., Labrak, Y., Ireland, G., Carradori, D., Dillenburg, A., Borger, E., Soong, D., Richardson, J. C., Kuhlmann, T., Williams, A., Pollard, J. W., des Rieux, A., Priller, J. & Miron, V. E., 10 Jun 2019, In : Nature Neuroscience. 22, 7, p. 1046–1052 7 p.

    Research output: Contribution to journalArticle

  12. Central nervous system regeneration--where are we?

    Williams, A., May 2014, In : QJM: An International Journal of Medicine. 107, 5, p. 335-9 5 p.

    Research output: Contribution to journalLiterature review

  13. Characterisation of immune cell infiltrates in the lesions of multiple sclerosis patients

    Zandee, S. E., Leech, M. D., Williams, A. & Anderton, S. M., Dec 2014, In : Immunology . 143, p. 140-140 1 p.

    Research output: Contribution to journalMeeting abstract

  14. Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system

    Piaton, G., Aigrot, M-S., Williams, A., Moyon, S., Tepavcevic, V., Moutkine, I., Gras, J., Matho, K. S., Schmitt, A., Soellner, H., Huber, A. B., Ravassard, P. & Lubetzki, C., Apr 2011, In : Brain. 134, 4, p. 1156-1167 12 p.

    Research output: Contribution to journalArticle

  15. Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish

    Muenzel, E. J., Schaefer, K., Obirei, B., Kremmer, E., Burton, E. A., Kuscha, V., Becker, C. G., Broesamle, C., Williams, A. & Becker, T., Feb 2012, In : Glia. 60, 2, p. 253-270 18 p.

    Research output: Contribution to journalArticle

  16. Comparative assessment of phototherapy protocols for reduction of oxidative stress in partially transected spinal cord slices undergoing secondary degeneration

    Ashworth, B. E., Stephens, E., Bartlett, C. A., Serghiou, S., Giacci, M. K., Williams, A., Hart, N. S. & Fitzgerald, M., 18 May 2016, In : BMC Neuroscience.

    Research output: Contribution to journalArticle

  17. Correlated Heterospectral Lipidomics for Biomolecular Profiling of Remyelination in Multiple Sclerosis

    Bergholt, M. S., Serio, A., McKenzie, J. S., Boyd, A., Soares, R. F., Tillner, J., Chiappini, C., Wu, V., Dannhorn, A., Takats, Z., Williams, A. & Stevens, M. M., 27 Dec 2017, In : ACS Central Science. 4, 1, p. 39-51 13 p.

    Research output: Contribution to journalArticle

  18. Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis

    Mendanha Falcão, A., van Bruggen, D., Marques, S., Meijer, M., Jaekel, S., Agirre, E., Samudyata, Floriddia, E. M., Vanichkina, D. P., Ffrench-Constant, C., Williams, A., Ortlieb Guerreiro-Cacais, A. & Castelo-Branco, G., 12 Nov 2018, In : Nature Medicine.

    Research output: Contribution to journalArticle

  19. Endothelial cell-oligodendrocyte interactions in small vessel disease and aging

    Rajani, R. M. & Williams, A., Mar 2017, In : Clinical science. 131, 5, p. 369-379 11 p.

    Research output: Contribution to journalArticle

  20. Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9

    Lindner, M., Thümmler, K., Arthur, A., Brunner, S., Elliott, C., McElroy, D., Mohan, H., Williams, A., Edgar, J. M., Schuh, C., Stadelmann, C., Barnett, S. C., Lassmann, H., Mücklisch, S., Mudaliar, M., Schaeren-Wiemers, N., Meinl, E. & Linington, C., 23 Apr 2015, In : Brain. 138, p. 1875-1893

    Research output: Contribution to journalArticle

  21. IL-10-producing, ST2-expressing Foxp3(+) T cells in multiple sclerosis brain lesions

    Zandee, S. E. J., O'Connor, R. A., Mair, I., Leech, M. D., Williams, A. & Anderton, S. M., 7 Feb 2017, In : Immunology and Cell Biology.

    Research output: Contribution to journalArticle

  22. Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination

    Yuen, T. J., Johnson, K. R., Miron, V. E., Zhao, C., Quandt, J., Harrisingh, M. C., Swire, M., Williams, A., McFarland, H. F., Franklin, R. J. M. & Ffrench-Constant, C., Apr 2013, In : Brain. 136, 4, p. 1035-1047 13 p.

    Research output: Contribution to journalArticle

  23. Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-11C]-2-(4′-methylaminophenyl)- 6-hydroxybenzothiazole

    Stankoff, B., Freeman, L., Aigrot, M-S., Chardain, A., Dolle, F., Williams, A., Galanaud, D., Armand, L., Lehericy, S., Lubetzki, C., Zalc, B. & Bottlaender, M., Apr 2011, In : Annals of Neurology. 69, 4, p. 673-680 8 p.

    Research output: Contribution to journalArticle

  24. Increasing Internodal Distance in Myelinated Nerves Accelerates Nerve Conduction to a Flat Maximum

    Wu, L. M. N., Williams, A., Delaney, A., Sherman, D. L. & Brophy, P. J., Oct 2012, In : Current Biology. 22, 20, p. 1957-1961 5 p.

    Research output: Contribution to journalArticle

  25. Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models

    Boyd, A., Zhang, H. & Williams, A., Jun 2013, In : Acta Neuropathologica. p. 1-19 19 p.

    Research output: Contribution to journalArticle

  26. Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease

    Ferrari Bardile, C., Garcia-Miralles, M., Caron, N. S., Rayan, N. A., Langley, S. R., Harmston, N., Rondelli, A. M., Teo, R. T. Y., Waltl, S., Anderson, L. M., Bae, H-G., Jung, S., Williams, A., Prabhakar, S., Petretto, E., Hayden, M. R. & Pouladi, M. A., 7 May 2019, In : Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalArticle

  27. Loss of PRMT1 in the CNS induces reactive astrocytes and microglia during postnatal brain development

    Hashimoto, M., Kumabe, A., Kim, J-D., Murata, K., Sekizar, S., Williams, A. C., Lu, W., Ishida, J., Nakagawa, T., Endo, M., Minami, Y. & Fukamizu, A., 16 Aug 2020, In : Journal of Neurochemistry.

    Research output: Contribution to journalArticle

  28. M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

    Miron, V. E., Boyd, A., Zhao, J-W., Yuen, T. J., Ruckh, J. M., Shadrach, J. L., van Wijngaarden, P., Wagers, A. J., Williams, A., Franklin, R. J. M. & Ffrench-Constant, C., 2013, In : Nature Neuroscience. 16, 9, p. 1211 - 1218 10 p.

    Research output: Contribution to journalArticle

  29. Mature oligodendrocytes bordering lesions limit demyelination and favor myelin repair via heparan sulphate production

    Macchi, M., Magalon, K., Zimmer, C., Peeva, E., El Waly, B., Brousse, B., Jaekel, S., Grobe, K., Kiefer, F., Williams, A. C., Cayre, M. & Durbec, P., 22 Jun 2020, In : eLIFE.

    Research output: Contribution to journalArticle

  30. Most Scottish neurologists do not apply the 2010 McDonald criteria when diagnosing multiple sclerosis

    Lumley, R., Davenport, R. & Williams, A., Mar 2015, In : Journal of the Royal College of Physicians of Edinburgh. 45, 1, p. 23-6 4 p.

    Research output: Contribution to journalArticle

  31. Most neurologists in Scotland do not use the mcdonald 2010 criteria to diagnose multiple sclerosis

    Lumley, R., Davenport, R. & Williams, A., Nov 2013, In : Journal of Neurology, Neurosurgery & Psychiatry. 84, 11, p. e2

    Research output: Contribution to journalArticle

  32. Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF)

    Rittchen, S., Boyd, A., Burns, A., Park, J., Fahmy, T. M., Metcalfe, S. & Williams, A., Jun 2015, In : Biomaterials. 56

    Research output: Contribution to journalArticle

  33. Opening the floodgates to the brain

    Moss, J. & Williams, A., 13 Mar 2020, Science.

    Research output: Book/ReportCommissioned report

  34. Promoting remyelination in multiple sclerosis-recent advances

    Jolanda Münzel, E. & Williams, A., Dec 2013, In : Drugs. 73, 18, p. 2017-29 13 p.

    Research output: Contribution to journalArticle

  35. Raman Imaging of Nanocarriers for Drug Delivery

    Vanden-Hehir, S., Tipping, W. J., Lee, M., Brunton, V. G., Williams, A. & Hulme, A. N., 3 Mar 2019, In : Nanomaterials. 9, 3

    Research output: Contribution to journalReview article

  36. Regulatory T cells promote myelin regeneration in the central nervous system

    Dombrowski, Y., O'Hagan, T., Dittmer, M., Penalva, R., Mayoral, S. R., Bankhead, P., Fleville, S., Eleftheriadis, G., Zhao, C., Naughton, M., Hassan, R., Moffat, J., Falconer, J., Boyd, A., Hamilton, P., Allen, I. V., Kissenpfennig, A., Moynagh, P. N., Evergren, E., Perbal, B. & 5 others, Williams, A. C., Ingram, R. J., Chan, J. R., Franklin, R. J. M. & Fitzgerald, D. C., 13 Mar 2017, In : Nature Neuroscience. 20, 5, p. 674-680 7 p.

    Research output: Contribution to journalArticle

  37. Relapsing-remitting multiple sclerosis and chronic idiopathic neutropenia: a challenging combination

    Münzel, E. J., Wimperis, J. Z. & Williams, A., 2013, In : BMJ Case Reports. 2013

    Research output: Contribution to journalArticle

  38. Remyelination in multiple sclerosis: from basic science to clinical translation

    Lubetzki, C., Zalc, B., Williams, A., Stadelmann, C. & Stankoff, B., 20 Jul 2020, In : Lancet Neurology.

    Research output: Contribution to journalArticle

  39. Remyelination in the central nervous system

    Zhang, H., Williams, A., Ffrench-Constant, C. & University of Edinburgh, 2013

    Research output: Other contribution

  40. Reprogramming of Fibroblasts to Oligodendrocyte Progenitor-like Cells Using CRISPR/Cas9-Based Synthetic Transcription Factors

    Matjusaitis, M., Wagstaff, L. J., Martella, A., Baranowski, B., Blin, C., Gogolok, S., Williams, A. & Pollard, S. M., 7 Nov 2019, In : Stem Cell Reports.

    Research output: Contribution to journalArticle

  41. Retinoid X receptor gamma signaling accelerates CNS remyelination

    Huang, J. K., Jarjour, A. A., Oumesmar, B. N., Kerninon, C., Williams, A., Krezel, W., Kagechika, H., Bauer, J., Zhao, C., Baron-Van Evercooren, A., Chambon, P., Ffrench-Constant, C. & Franklin, R. J. M., Jan 2011, In : Nature Neuroscience. 14, 1, p. 45-53 9 p.

    Research output: Contribution to journalArticle

  42. Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats

    Rajani, R. M., Quick, S., Ruigrok, S. R., Graham, D., Harris, S. E., Verhaaren, B. F. J., Fornage, M., Seshadri, S., Atanur, S. S., Dominiczak, A. F., Smith, C., Wardlaw, J. M. & Williams, A., 4 Jul 2018, In : Science Translational Medicine. 10, 448, p. eaam9507

    Research output: Contribution to journalArticle

  43. Scaffold-Mediated Sustained, Non-viral Delivery of miR-219/miR-338 Promotes CNS Remyelination

    Milbreta, U., Lin, J., Pinese, C., Ong, W., Chin, J. S., Shirahama, H., Mi, R., Williams, A., Bechler, M. E., Wang, J., Ffrench-Constant, C., Hoke, A. & Chew, S. Y., 6 Feb 2019, In : Molecular Therapy. 27, 2

    Research output: Contribution to journalArticle

  44. Stochastic spatial modelling of the remyelination process in multiple sclerosis lesions

    Luisa Vissat, L., Hillston, J. & Williams, A., 12 Jun 2019, Automated Reasoning for Systems Biology and Medicine. Liò, P. & Zuliani, P. (eds.). Springer, p. 299-326 28 p. (Computational Biology; vol. 30).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  45. TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells

    Ni Choileain, S., Hay, J., Thomas, J., Williams, A., Vermeren, M. M., Benezech, C., Gomez-salazar, M., Hugues, O. R., Vermeren, S., Howie, S. E. M., Dransfield, I. & Astier, A. L., 24 Oct 2017, In : Science Signaling. 10, 502, p. eaah6163

    Research output: Contribution to journalArticle

  46. The Lysosomal Transcription Factor TFEB represses myelination downstream of the Rag-Ragulator complex

    Meireles, A. M., Shen, K., Zoupi, L., Iyer, H., Bouchard, E. L., Williams, A. & Talbot, W. S., 5 Nov 2018, In : Developmental Cell.

    Research output: Contribution to journalArticle

  47. The Polarity Protein Scribble Regulates Myelination and Remyelination in the Central Nervous System

    Jarjour, A. A., Boyd, A., Dow, L. E., Holloway, R. K., Goebbels, S., Humbert, P. O., Williams, A. & Ffrench-Constant, C., 25 Mar 2015, In : PLoS Biology. 13, 3, e1002107.

    Research output: Contribution to journalArticle

Previous 1 2 Next