Edinburgh Research Explorer

Prof Bernadette Dutia

(Former employee or visitor)

Profile photo

Willingness to take Ph.D. students: Yes

Education/Academic qualification

1979Doctor of Philosophy (PhD), University of Glasgow
1975Bachelor of Science, University of Canterbury

Current Research Interests

Molecular pathogenesis of herpesvirus and influenza virus infections.

Research Interests

My research revolves around the pathogenesis of virus infections.  This involves the study of host-virus interactions at the level of both virus and host.  I am interested in the role of virus genes in the virus life cycle and how specific genes interact with and manipulate host responses to ensure efficient and effective virus replication and in the function of individual host genes in control of virus infections, particularly those involved in innate immunity. The viruses that I work with include members of the herpesvirus family, in particular the gammaherpesvirus murid herpesvirus 4 which is an important model system for the study of gammaherpesvirus infections in their natural host, and influenza A virus.  Murid herpesvirus 4 genes of interest include the vtRNAs and miRNAs and the chemokine binding molecule M4.  Work on influenza virus includes study of the role of macrophages in virus infection, the role of interferon gamma in macrophage activation, and the development of novel antiviral agents.  

Biography

I obtained my first degree in biochemistry at Lincoln College in the University of Canterbury in New Zealand.  I was awarded a Commonwealth Scholarship to study for a PhD in the UK and did my PhD in the Department of Biochemistry at the University of Glasgow on the development and use of in vitro translation systems for the study of herpesvirus encoded proteins.  I returned to New Zealand to do a postdoc at the University of Otago before joining the MRC Virology Unit in Glasgow as a non-clinical scientist where I worked on Herpes simplex virus encoded enzymes and their role in virus infections.  In 1985 I moved to the Royal (Dick) School of Veterinary Studies in the University of Edinburgh to work on the ovine immune system, in particular the characterisation of the ovine MHC class II molecules and functional roles.  In 1994 my research focus moved to the study of virus pathogenesis combining my interests in viral diseases with my interests in immune system function.  

My research in a nutshell

 To hear Bernadette talk about her research please visit click here.

Qualifications

BSc (hons) 1st class, Biochemistry, University of Canterbury, New Zealand, 1975

PhD, Biochemistry, University of Glasgow, 1979

Research Groups

Roslin Institute, Digard group

Roslin Institute, Baillie group

Collaborative Activity

Biography

Prof James Stewart, University of Liverpool

Dr Michael Jarvis, University of Plymouth

Research students

1990-1993

 (Co-supervisor) Elaine D. Ferguson

1991-1995

 (Co-supervisor) Paula E. Keating

1993-1996

 (Co-supervisor) Susan M. Rhind

1998-2001

 (Co-supervisor) Flora Wan

1999-2002

 (Co-supervisor) Suganya Selvarajah

2000-2003

 (Co-supervisor) Alan Townsley

2002-2006

 (Co-supervisor) Babunilayam Gangadharan

2002-2005

 (Co-supervisor) Anna Cliffe

2002-2006

 (Co-supervisor) Kerra Templeton

2002-2007

 Principal Supervisor, Chia-Chun Hou

2003-2007

 Principal Supervisor, Sarah Fraser

2003-2007

 (Co-supervisor) Catherine Dixon

2003-2007

 Principal Supervisor, Rona Thomson

2006-2010

 Principal Supervisor, Nila Roy Choudhury

2007-2011

 Principal Supervisor, Gillian Campbell

2007-2011

 Principal Supervisor, Tara Crook

2008-2013

 Principal Supervisor, Xuan Wang

2008-2012

 (Co-supervisor) Shuo Li

2009-2013

 (Co-supervisor) Nouf Laqtom

2010-2013

 (Co-supervisor), Shoko Nishiyama

2011-2015

 Principal Supervisor, Amr Bayoumy

2012-2015

 Principal Supervisor, Gareth Hardisty

2011-2015

 (Co-supervisor) Pankaj Chakraborty

2011-2016

2012-2016

2013-

2013-

2014-

2015-

 (Co-supervisor) Diwakar Kumar

 (Co-supervisor) Matthew Turnbull

 (Co-supervisor) Rebecca Dewar

 (Co-supervisor) Mariya Goncheva

 (Co-supervisor) Saranya Ramachandran

 (Co-supervisor) Rute Pinto

 

Research activities & awards

  1. Royal Highland Show

    Activity: Participating in or organising an event typesPublic Engagement – Festival/Exhibition

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