Edinburgh Research Explorer

Bettina Böttcher

(Former employee or visitor)

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  1. 2016

  2. Biophysical Characterization and Activity of Lymphostatin, a Multifunctional Virulence Factor of Attaching and Effacing Escherichia coli

    Cassady-Cain, R. L., Blackburn, E. A., Alsarraf, H., Dedic, E., Bease, A. G., Böttcher, B., Jørgensen, R., Wear, M. & Stevens, M. P., 11 Mar 2016, In: Journal of Biological Chemistry. 291, 11, p. 5803-5816

    Research output: Contribution to journal › Article › peer-review

  3. Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans.

    Currie, S. M., Gwyer Findlay, E., McFarlane, A., Fitch, P., Boettcher, A., Colegrave, N., Paras, A., Jozwik, A., Chiu, C., Schwarze, J. & Davidson, D. J., 12 Feb 2016, In: Journal of Immunology. 196, 6, p. 2699-2710 11 p.

    Research output: Contribution to journal › Article › peer-review

  4. 2015

  5. The Structure of YnaI Implies Structural and Mechanistic Conservation in the MscS Family of Mechanosensitive Channels

    Böttcher, B., Prazak, V., Rasmussen, A., Black, S. S. & Rasmussen, T., 1 Sep 2015, In: Structure. 23, 9, p. 1705-1714 10 p.

    Research output: Contribution to journal › Article › peer-review

  6. Electron cryomicroscopy and image reconstruction of viral nanoparticles

    Böttcher, B., 6 Jul 2015, Viral Nanotechnology. Pumpens, P. & Khudyakov, Y. (eds.). 1st ed. CRC Uniscience Publication, CRC Press Inc, p. 27-60 34 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  7. A recombinant expression system for differentially phosphorylated hepatitis B virus capsids

    Heger-Stevic, J. K., Bisse, E., Boettcher, B., Kolb, P., Pfister, A. & Nassal, M., 25 Jun 2015, In: Journal of Viral Hepatitis. 22, p. 4-5 2 p.

    Research output: Contribution to journal › Meeting abstract

  8. 2013

  9. Crystal structure of Schmallenberg orthobunyavirus nucleoprotein-RNA complex reveals a novel RNA sequestration mechanism

    Dong, H., Li, P., Böttcher, B., Elliott, R. M. & Dong, C., Aug 2013, In: RNA. 19, 8, p. 1129-1136 8 p.

    Research output: Contribution to journal › Article › peer-review

  10. 2012

  11. Transmission electron microscopy: Preparation of specimens

    Boettcher, B., 15 Jun 2012, Wiley Online Library. John Wiley & Sons Inc.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed)

  12. Modular architecture of eukaryotic RNase P and RNase MRP revealed by electron microscopy

    Hipp, K., Galani, K., Batisse, C., Prinz, S. & Boettcher, B., Apr 2012, In: Nucleic Acids Research. 40, 7, p. 3275-3288 14 p.

    Research output: Contribution to journal › Article › peer-review

  13. Assembly of the eukaryotic PLP-synthase complex from plasmodium and activation of the Pdx1 enzyme

    Guedez, G., Hipp, K., Windeisen, V., Derrer, B., Gengenbacher, M., Boettcher, B., Sinning, I., Kappes, B. & Tews, I., 11 Jan 2012, In: Structure. 20, 1, p. 172-184 13 p.

    Research output: Contribution to journal › Article › peer-review

  14. Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits

    Lebaron, S., Schneider, C., van Nues, R. W., Swiatkowska, A., Walsh, D., Böttcher, B., Granneman, S., Watkins, N. J. & Tollervey, D., 2012, In: Nature Structural & Molecular Biology. 19, 8, p. 744–753

    Research output: Contribution to journal › Article › peer-review

  15. Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel

    Bradatsch, B., Leidig, C., Granneman, S., Gnädig, M., Tollervey, D., Böttcher, B., Beckmann, R. & Hurt, E., 2012, In: Nature Structural & Molecular Biology.

    Research output: Contribution to journal › Article › peer-review

  16. The mitosis and neurodevelopment proteins NDE1 and NDEL1 form dimers, tetramers and polymers with a folded-back structure in solution

    Soares, D. C., Bradshaw, N. J., Zou, J., Kennaway, C. K., Hamilton, R. S., Chen, Z. A., Wear, M. A., Blackburn, E. A., Bramham, J., Boettcher, B., Millar, J. K., Barlow, P. N., Walkinshaw, M. D., Rappsilber, J. & Porteous, D. J., 2012, In: Journal of Biological Chemistry. 287, 39, p. 32381-32393

    Research output: Contribution to journal › Article › peer-review

  17. 2011

  18. The Assembly-Activating Protein Promotes Capsid Assembly of Different Adeno-Associated Virus Serotypes

    Sonntag, F., Koether, K., Schmidt, K., Weghofer, M., Raupp, C., Nieto, K., Kuck, A., Gerlach, B., Boettcher, B., Mueller, O. J., Lux, K., Hoerer, M. & Kleinschmidt, J. A., Dec 2011, In: Journal of Virology. 85, 23, p. 12686-12697 12 p.

    Research output: Contribution to journal › Article › peer-review

  19. Insights into the structure of the CCR4-NOT complex by electron microscopy

    Nasertorabi, F., Batisse, C., Diepholz, M., Suck, D. & Boettcher, B., 21 Jul 2011, In: FEBS Letters. 585, 14, p. 2182-2186 5 p.

    Research output: Contribution to journal › Article › peer-review

  20. Conformational Changes in Adeno-Associated Virus Type 1 Induced by Genome Packaging

    Gerlach, B., Kleinschmidt, J. A. & Boettcher, B., 10 Jun 2011, In: Journal of Molecular Biology. 409, 3, p. 427-438 12 p.

    Research output: Contribution to journal › Article › peer-review

  21. Analyzing RNA polymerase III by electron cryomicroscopy

    Fernandez-Tornero, C., Boettcher, B., Rashid, U. J. & Mueller, C. W., 2011, In: Rna biology. 8, 5, p. 760-765 6 p.

    Research output: Contribution to journal › Editorial › peer-review

  22. 2010

  23. Conformational flexibility of RNA polymerase III during transcriptional elongation

    Fernandez-Tornero, C., Boettcher, B., Rashid, U. J., Steuerwald, U., Floerchinger, B., Devos, D. P., Lindner, D. & Mueller, C. W., 17 Nov 2010, In: EMBO Journal. 29, 22, p. 3762-3772 11 p.

    Research output: Contribution to journal › Article › peer-review

  24. Systematic Bioinformatics and Experimental Validation of Yeast Complexes Reduces the Rate of Attrition during Structural Investigations

    Brooks, M. A., Gewartowski, K., Mitsiki, E., Letoquart, J., Pache, R. A., Billier, Y., Bertero, M., Correa, M., Czarnocki-Cieciura, M., Dadlez, M., Henriot, V., Lazar, N., Delbos, L., Lebert, D., Piwowarski, J., Rochaix, P., Böettcher, B., Serrano, L., Seraphin, B., van Tilbeurgh, H. & 3 others, Aloy, P., Perrakis, A. & Dziembowski, A., 8 Sep 2010, In: Structure. 18, 9, p. 1075-1082 8 p.

    Research output: Contribution to journal › Article › peer-review

  25. Precise mapping of subunits in multiprotein complexes by a versatile electron microscopy label

    Flemming, D., Thierbach, K., Stelter, P., Boettcher, B. & Hurt, E., Jun 2010, In: Nature Structural & Molecular Biology. 17, 6, p. 775-U152 5 p.

    Research output: Contribution to journal › Article › peer-review

  26. Regulatory assembly of the vacuolar proton pump VOV1-ATPase in yeast cells by FLIM-FRET

    Ernst, S., Batisse, C., Zarrabi, N., Boettcher, B. & Boersch, M., 2010, MULTIPHOTON MICROSCOPY IN THE BIOMEDICAL SCIENCES X. Periasamy, A., So, PTC. & Konig, K. (eds.). BELLINGHAM: SPIE, p. - 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  27. SINGLE-PARTICLE APPLICATIONS AT INTERMEDIATE RESOLUTION

    Boettcher, B. & Hipp, K., 2010, ADVANCES IN PROTEIN CHEMISTRY AND STRUCTURAL BIOLOGY: RECENT ADVANCES IN ELECTRON CRYOMICROSCOPY, PT A. SAN DIEGO: ELSEVIER ACADEMIC PRESS INC, p. 61-88 28 p.

    Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution

  28. 2009

  29. Purification of Nuclear Poly(A)-binding Protein Nab2 Reveals Association with the Yeast Transcriptome and a Messenger Ribonucleoprotein Core Structure

    Batisse, J., Batisse, C., Budd, A., Boettcher, B. & Hurt, E., 11 Dec 2009, In: Journal of Biological Chemistry. 284, 50, p. 34911-34917 7 p.

    Research output: Contribution to journal › Article › peer-review

  30. Proteome Organization in a Genome-Reduced Bacterium

    Kuehner, S., van Noort, V., Betts, M. J., Leo-Macias, A., Batisse, C., Rode, M., Yamada, T., Maier, T., Bader, S., Beltran-Alvarez, P., Castano-Diez, D., Chen, W-H., Devos, D., Gueell, M., Norambuena, T., Racke, I., Rybin, V., Schmidt, A., Yus, E., Aebersold, R. & 7 others, Herrmann, R., Boettcher, B., Frangakis, A. S., Russell, R. B., Serrano, L., Bork, P. & Gavin, A-C., 27 Nov 2009, In: Science. 326, 5957, p. 1235-1240 6 p.

    Research output: Contribution to journal › Article › peer-review

  31. Mechanochemical Removal of Ribosome Biogenesis Factors from Nascent 60S Ribosomal Subunits

    Ulbrich, C., Diepholz, M., Bassler, J., Kressler, D., Pertschy, B., Galani, K., Boettcher, B. & Hurt, E., 4 Sep 2009, In: Cell. 138, 5, p. 911-922 12 p.

    Research output: Contribution to journal › Article › peer-review

  32. Solution structure of the KdpFABC P-type ATPase from Escherichia coli by electron microscopic single particle analysis

    Heitkamp, T., Boettcher, B. & Greie, J-C., 30 Jun 2009, In: Journal of Structural Biology. 166, 3, p. 295-302 8 p.

    Research output: Contribution to journal › Article › peer-review

  33. Two structurally distinct domains of the nucleoporin Nup 170 cooperate to tether a subset of nucleoporins to nuclear pores

    Flemming, D., Sarges, P., Stelter, P., Hellwig, A., Boettcher, B. & Hurt, E., 4 May 2009, In: Journal of Cell Biology. 185, 3, p. 387-395 9 p.

    Research output: Contribution to journal › Article › peer-review

  34. 2008

  35. A Different Conformation for EGC Stator Subcomplex in Solution and in the Assembled Yeast V-ATPase: Possible Implications for Regulatory Disassembly

    Diepholz, M., Venzke, D., Prinz, S., Batisse, C., Floerchinger, B., Roessle, M., Svergun, D. I., Boettcher, B. & Fethiere, J., 10 Dec 2008, In: Structure. 16, 12, p. 1789-1798 10 p.

    Research output: Contribution to journal › Article › peer-review

  36. Nucleotide-induced conformational changes in the Escherichia coli NADH:ubiquinone oxidoreductase (complex I)

    Pohl, T., Schneider, D., Hielscher, R., Stolpe, S., Doerner, K., Kohlstaedt, M., Boettcher, B., Hellwig, P. & Friedrich, T., Oct 2008, In: Biochemical Society Transactions. 36, p. 971-975 5 p.

    Research output: Contribution to journal › Article › peer-review

  37. Structural organization of the V-ATPase and its implications for regulatory assembly and disassembly

    Diepholz, M., Boersch, M. & Boettcher, B., Oct 2008, In: Biochemical Society Transactions. 36, p. 1027-1031 5 p.

    Research output: Contribution to journal › Article › peer-review

  38. Substrate crosstalk involving conformational changes in E-coli respiratory complex I

    Doerner, K., Schneider, D., Stolpe, S., Boettcher, B., Hellwig, P. & Friedric, T., 19 Jul 2008, In: BBA - Bioenergetics. 1777, p. S37-S37 1 p.

    Research output: Contribution to journal › Meeting abstract › peer-review

  39. The Leishmania tarentolae exosome: Purification and structural analysis by electron microscopy

    Cristodero, M., Boettcher, B., Diepholz, M., Scheffzek, K. & Clayton, C., May 2008, In: Molecular and Biochemical Parasitology. 159, 1, p. 24-29 6 p.

    Research output: Contribution to journal › Article › peer-review

  40. K+-translocating KdpFABC P-type ATPase from Escherichia coli acts as a functional and structural dimer

    Heitkamp, T., Kalinowski, R., Boettcher, B., Boersch, M., Altendorf, K. & Greie, J-C., 18 Mar 2008, In: Biochemistry. 47, 11, p. 3564-3575 12 p.

    Research output: Contribution to journal › Article › peer-review

  41. 2006

  42. Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit

    Schafer, T., Maco, B., Petfalski, E., Tollervey, D., Böttcher, B., Aebi, U. & Hurt, E., 1 Jun 2006, In: Nature. 441, 7093, p. 651-655 5 p.

    Research output: Contribution to journal › Article › peer-review