Edinburgh Research Explorer

Prof Bill Earnshaw

Professor of Chromosome Dynamics

  1. 3D-CLEM reveals that a major portion of mitotic chromosomes is not Chromatin

    Booth, D., Beckett, A. J., Molina, O., Samejima, I., Masumoto, H., Kouprina, N., Larionov, V., Prior, I. A. & Earnshaw, W., 17 Nov 2016, In : Molecular Cell.

    Research output: Contribution to journalArticle

  2. De novo formation and epigenetic maintenance of centromere chromatin

    Ohzeki, J., Larionov, V., Earnshaw, W. C. & Masumoto, H., 1 Jun 2019, In : Current opinion in cell biology. 58, p. 15-25 11 p.

    Research output: Contribution to journalReview article

  3. In vitro BioID: Mapping the CENP-A microenvironment with high temporal and spatial resolution

    Remnant, L., Booth, D. G., Vargiu, G., Spanos, C., Kerr, A. R. W. & Earnshaw, W. C., 20 Mar 2019, In : Molecular Biology of the Cell. 30, 11, p. 1314-1325 12 p.

    Research output: Contribution to journalArticle

  4. A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

    Ladds, M. J. G. W., van Leeuwen, I. M. M., Drummond, C. J., Chu, S., Healy, A. R., Popova, G., Pastor Fernández, A., Mollick, T., Darekar, S., Sedimbi, S. K., Nekulova, M., Sachweh, M. C. C., Campbell, J., Higgins, M., Tuck, C., Popa, M., Safont, M. M., Gelebart, P., Fandalyuk, Z., Thompson, A. M. & 26 others, Svensson, R., Gustavsson, A-L., Johansson, L., Färnegårdh, K., Yngve, U., Saleh, A., Haraldsson, M., D'Hollander, A. C. A., Franco, M., Zhao, Y., Håkansson, M., Walse, B., Larsson, K., Peat, E. M., Pelechano, V., Lunec, J., Vojtesek, B., Carmena, M., Earnshaw, W. C., McCarthy, A. R., Westwood, N. J., Arsenian-Henriksson, M., Lane, D. P., Bhatia, R., McCormack, E. & Laín, S., 16 Mar 2018, In : Nature Communications. 9, 1, 14 p., 1107 (2018).

    Research output: Contribution to journalArticle

  5. A Human Artificial Chromosome (HAC) with a conditional centromere

    Masumoto, H., Ohzeki, J., Nakano, M., Bergmann, J., Noskov, V., Kouprina, N., Earnshaw, W. & Larionov, V., Dec 2010, In : Genes & genetic systems. 85, 6, p. 458-458 1 p.

    Research output: Contribution to journalMeeting abstract

  6. A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

    Lee, H-S., Lee, N. C. O., Samoshkin, A., Kononenko, A. V., Kouprina, N., Larionov, V., Grimes, B. R., Bansal, R., Masumoto, H. & Earnshaw, W. C., 22 May 2013, In : BMC Cancer. 13, 12 p., 252.

    Research output: Contribution to journalArticle

  7. A new generation of human artificial chromosomes for functional genomics and gene therapy

    Kouprina, N., Larionov, V., Earnshaw, W. C. & Masumoto, H., 1 Apr 2013, In : Cellular and Molecular Life Sciences. 70, 7, p. 1135-1148 14 p.

    Research output: Contribution to journalArticle

  8. A novel assay to screen siRNA libraries identifies protein kinases as required for chromosome transmission

    Liskovykh, M., Goncharov, N. V., Petrov, N., Aksenova, V., Pegoraro, G., Ozbun, L. L., Reinhold, W. C., Varma, S., Dasso, M., Kumeiko, V., Masumoto, H., Earnshaw, W. C., Larionov, V. & Kouprina, N., 12 Sep 2019, In : Genome Research. 29, 9

    Research output: Contribution to journalArticle

  9. A pathway for mitotic chromosome formation

    Gibcus, J. H., Samejima, K., Goloborodko, A., Samejima, I., Naumova, N., Nuebler, J., Kanemaki, M. T., Xie, L., Paulson, J. R., Earnshaw, W. C., Mirny, L. A. & Dekker, J., 9 Feb 2018, In : Science. 359, 6376, 14 p., eaao6135.

    Research output: Contribution to journalArticle

  10. A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function

    Kononenko, A. V., Bansal, R., Lee, N. C. O., Grimes, B. R., Masumoto, H., Earnshaw, W. C., Larionov, V. & Kouprina, N., 1 Dec 2014, In : Nucleic Acids Research. 42, 21, e164.

    Research output: Contribution to journalArticle

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