Edinburgh Research Explorer

Bill Earnshaw

Professor of Chromosome Dynamics

  1. 2015
  2. Discovering centromere proteins: from cold white hands to the A, B, C of CENPs

    Earnshaw, W. C., 23 Jun 2015, In : Nature reviews Molecular cell biology. 16, 7, p. 443-449 7 p.

    Research output: Contribution to journalArticle

  3. Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes

    Platani, M., Trinkle-Mulcahy, L., Porter, M., Arulanandam, A. & Earnshaw, W. C., 6 Jul 2015, In : Journal of Cell Biology. 210, 1, p. 45-62 18 p.

    Research output: Contribution to journalArticle

  4. TD-60 links RalA GTPase function to the CPC in mitosis

    Papini, D., Langemeyer, L., Abad, M. A., Kerr, A., Samejima, I., Eyers, P. A., Arulanandam, A., Higgins, J. M. G., Barr, F. A. & Earnshaw, W. C., 9 Jul 2015, In : Nature Communications. 6, 7678.

    Research output: Contribution to journalArticle

  5. Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development

    González-Loyola, A., Fernández-Miranda, G., Trakala, M., Partida, D., Samejima, K., Ogawa, H., Cañamero, M., de Martino, A., Martínez-Ramírez, Á., de Cárcer, G., de Castro., I. P., Earnshaw, W. C. & Malumbres, M., 3 Aug 2015, In : Molecular and Cellular Biology. 35, 20, p. 3566-3578 13 p.

    Research output: Contribution to journalArticle

  6. The inner centromere protein (INCENP) coil is a single α-helix (SAH) domain that binds directly to microtubules and is important for chromosome passenger complex (CPC) localization and function in mitosis

    Samejima, K., Platani, M., Wolny, M., Ogawa, H., Vargiu, G., Knight, P. J., Peckham, M. & Earnshaw, W. C., 28 Aug 2015, In : Journal of Biological Chemistry. 290, 35, p. 21460-21472 13 p.

    Research output: Contribution to journalArticle

  7. Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore

    Samejima, I., Spanos, C., De Lima Alves, F., Hori, T., Perpelescu, M., Zou, J., Rappsilber, J., Fukagawa, T. & Earnshaw, W. C., 14 Dec 2015, In : Journal of Cell Biology. 211, 6, p. 1141-1156 16 p.

    Research output: Contribution to journalArticle

  8. 2016
  9. Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3

    Martins, N. M. C., Bergmann, J. H., Shono, N., Kimura, H., Larionov, V., Masumoto, H. & Earnshaw, W. C., 1 Jan 2016, In : Molecular Biology of the Cell. 27, 1, p. 177-96 20 p.

    Research output: Contribution to journalArticle

  10. Auxin/AID versus conventional knockouts: Distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability

    Wood, L., Booth, D. G., Vargiu, G., Ohta, S., deLima Alves, F., Samejima, K., Fukagawa, T., Rappsilber, J. & Earnshaw, W. C., 20 Jan 2016, In : Open Biology. 6, 1, 150230.

    Research output: Contribution to journalArticle

  11. Development of a novel HAC-based "gain of signal" quantitative assay for measuring chromosome instability (CIN) in cancer cells

    Kim, J. H., Lee, H. S., Lee, N. C. O., Goncharov, N. V., Kumeiko, V., Masumoto, H., Earnshaw, W. C., Kouprina, N. & Larionov, V., 22 Mar 2016, In : Oncotarget. 7, 12, p. 14841-14856 16 p.

    Research output: Contribution to journalArticle

  12. KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation

    Ohzeki, J-I., Shono, N., Otake, K., Martins, N. M. C., Kugou, K., Kimura, H., Nagase, T., Larionov, V., Earnshaw, W. C. & Masumoto, H., 6 Jun 2016, In : Developmental Cell. 37, 5, p. 413-27 15 p.

    Research output: Contribution to journalArticle