Edinburgh Research Explorer

Bill Earnshaw

Professor of Chromosome Dynamics

  1. Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα

    Samejima, K., Samejima, I., Vagnarelli, P., Ogawa, H., Vargiu, G., Kelly, D. A., Alves, F. L., Kerr, A., Ohta, S., Rappsilber, J., Earnshaw, W. C., Green, L. C., Hudson, D. F., Farr, C. J. & Cooke, C. A., 1 Nov 2012, In : Journal of Cell Biology. 199, 5, p. 755-770 16 p.

    Research output: Contribution to journalArticle

  2. Mitotic post-translational modifications of histones promote chromatin compaction in vitro

    Zhiteneva, A., Bonfiglio, J. J., Makarov, A., Colby, T., Vagnarelli, P., Schirmer, E. C., Matic, I. & Earnshaw, W. C., 13 Sep 2017, In : Open Biology. 7, 9

    Research output: Contribution to journalArticle

  3. Molecular Basis for Cdk1 Regulated Timing of Mis18 Complex Assembly and CENP-A Deposition

    Spiller, F., Medina-Pritchard, B., Alba Abad, M., Wear, M., Molina, O., Earnshaw, W. & Arulanandam, A., 4 Apr 2017, In : EMBO Reports. e201643564.

    Research output: Contribution to journalArticle

  4. Molecular and Genetic Analysis of Condensin Function in Vertebrate Cells

    Hudson, D. F., Ohta, S., Freisinger, T., MacIsaac, F., Sennels, L., Alves, F., Lai, F., Kerr, A., Rappsilber, J. & Earnshaw, W. C., 2008, In : Molecular Biology of the Cell. 19, 7, p. 3070-3079 10 p.

    Research output: Contribution to journalArticle

  5. Mps1 Phosphorylates Its N-Terminal Extension to Relieve Autoinhibition and Activate the Spindle Assembly Checkpoint

    Combes, G., Barysz, H., Garand, C., Gama Braga, L., Alharbi, I., Thebault, P., Murakami, L., Bryne, D. P., Stankovic, S., Eyers, P. A., Bolanos-Garcia, V. M., Earnshaw, W. C., Maciejowski, J., Jallepalli, P. V. & Elowe, S., 19 Mar 2018, In : Current biology : CB. 28, 6, p. 872-883 17 p.

    Research output: Contribution to journalArticle

  6. Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling

    Griffith, E., Walker, S., Martin, C-A., Vagnarelli, P., Stiff, T., Vernay, B., Al Sanna, N., Saggar, A., Hamel, B., Earnshaw, W. C., Jeggo, P. A., Jackson, A. P. & O'Driscoll, M., Feb 2008, In : Nature Genetics. 40, 2, p. 232-236 5 p.

    Research output: Contribution to journalArticle

  7. Nano Random Forests to mine protein complexes and their relationships in quantitative proteomics data

    Montaño-gutierrez, L., Ohta, S., Kustatscher, G., Earnshaw, B. & Rappsilber, J., 5 Jan 2017, In : Molecular Biology of the Cell.

    Research output: Contribution to journalArticle

  8. Nap1 regulates proper CENP-B binding to nucleosomes

    Tachiwana, H., Miya, Y., Shono, N., Ohzeki, J-I., Osakabe, A., Otake, K., Larionov, V., Earnshaw, W. C., Kimura, H., Masumoto, H. & Kurumizaka, H., 2013, In : Nucleic Acids Research. 41, 5, p. 2869-2880 12 p.

    Research output: Contribution to journalArticle

  9. Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere

    Kouprina, N., Samoshkin, A., Erliandri, I., Nakano, M., Lee, H-S., Fu, H., Iida, Y., Aladjem, M., Oshimura, M., Masumoto, H., Earnshaw, W. C. & Larionov, V., 21 Dec 2012, In : ACS Synthetic Biology. 1, 12, p. 590-601 12 p.

    Research output: Contribution to journalArticle

  10. PREditOR: A synthetic biology approach to removing heterochromatin from cells

    Molina, O., Carmena, M., Maudlin, I. E. & Earnshaw, W. C., 6 Dec 2016, In : Chromosome Research. 24, 4, p. 495-509

    Research output: Contribution to journalArticle