Edinburgh Research Explorer

Prof Brendan Corcoran

Personal Chair of Veterinary Cardiopulmonary Medicine

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Phone: +44 (0)131 650 7650

Willingness to take PhD students: Yes

Cellular, Molecular and Ultrastructural Aspects of Canine Mitral Valve Disease

Education/Academic qualification

Doctor of Philosophy (PhD), University of Edinburgh
Bachelors in Veterinary Medicine, University College Dublin

Professional Qualifications

Member of the Royal College of Veterinary Surgeons, MRCVS

Area of Expertise

Research expertiseVeterinary Medicine, Professional Governance, Veterinary Clinical Research, Internationalisation in a University context

Current Research Interests

Mitral valve disease in dogs, tissue engineered solutions to sourcing valve tissue for research.

Websites

www.roslin.ed.ac.uk

Administrative Roles

Chair Veterinary Clinical Audit Committee

Biography

After several years in private practice in New York and in London, I joined the R(D)SVS as a small animal clinician in 1986 and since then developed an interest in cardiology and respiratory medicine of dogs and cats, and have been Head of the Cardiopulmonary Service, Head of the Clinical Division and Director of the Hospital for Small Animals. This clinical career was interrupted by a three year Wellcome Leave Fellowship in respiratory physiology. My research interests had been initially in respiratory medicine and physiology, but more latterly has concentrated on mitral valve disease at all levels from clinical features to molecular mechanisms.

My current main research interest is in the molecular mechanisms that control mitral valve disease pathogenensis, using a combination of native valve tissue, valve cell culture systems and tissue engineered platforms. At present we are working on understanding the contibution of TGFβ to this disease and the important down-stream signals.

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