Edinburgh Research Explorer

Brian Walker

(Former employee or visitor)

  1. 11 beta HSD1-/- mice have enhanced angiogenic response and improved myodardial function following coronary artery ligation

    Small, G. R., Hadoke, P. W. F., Gray, G. A., Sharif, I., Mullins, J. J., Seckl, J. R. & Walker, B. R., Oct 2004, In : Hypertension. 44, 4, p. 587-587 1 p.

    Research output: Contribution to journalArticle

  2. 11 beta-Hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics

    Sandeep, T. C., Yau, J. L. W., MacLullich, A. M. J., Noble, J., Deary, I. J., Walker, B. R. & Seckl, J. R., 27 Apr 2004, In : Proceedings of the National Academy of Sciences (PNAS). 101, 17, p. 6734-6739 6 p.

    Research output: Contribution to journalArticle

  3. 11 beta-Hydroxysteroid dehydrogenase type 1 as a therapeutic target in metabolic syndrome and beyond

    Walker, B. R. & Seckl, J. R., 26 Mar 2006, In : Abstracts of Papers - American Chemical Society, National Meeting. 231, 1 p.

    Research output: Contribution to journalMeeting abstract

  4. 11 beta-Hydroxysteroid dehydrogenase type 1 is a predominant 11 beta-reductase in the intact perfused rat liver

    Jamieson, P. M., Walker, B. R., Chapman, K. E., Andrew, R., Rossiter, S. & Seckl, J. R., Jun 2000, In : Journal of Endocrinology. 165, 3, p. 685-692 8 p.

    Research output: Contribution to journalArticle

  5. 11 beta-hydroxysteroid dehydrogenase type 2 in mouse aorta - Localization and influence on response to glucocorticoids

    Christy, C., Hadoke, P. W. F., Paterson, J. M., Mullins, J. J., Seckl, J. R. & Walker, B. R., Oct 2003, In : Hypertension. 42, 4, p. 580-587 8 p.

    Research output: Contribution to journalArticle

  6. 11-Beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors in type 2 diabetes mellitus and obesity

    Hughes, K. A., Webster, S. P. & Walker, B. R., Apr 2008, In : Expert opinion on investigational drugs. 17, 4, p. 481-96 16 p.

    Research output: Contribution to journalLiterature review

  7. 11β-HSD1 inhibitors for the treatment of type 2 diabetes and cardiovascular disease

    Anderson, A. & Walker, B. R., Sep 2013, In : Drugs. 73, 13, p. 1385-1393 9 p.

    Research output: Contribution to journalArticle

  8. 11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI

    Mylonas, K. J., Turner, N. A., Bageghni, S. A., Kenyon, C. J., White, C. I., McGregor, K., Kimmitt, R. A., Sulston, R., Kelly, V., Walker, B. R., Porter, K. E., Chapman, K. E. & Gray, G. A., 1 Jun 2017, In : Journal of Endocrinology. 233, 3, p. 315-327 13 p.

    Research output: Contribution to journalArticle

  9. 11β-Hydroxysteroid Dehydrogenase Activity in the Brain Does Not Contribute to Systemic Interconversion of Cortisol and Cortisone in Healthy Men

    Kilgour, A. H. M., Semple, S., Marshall, I., Andrews, P., Andrew, R. & Walker, B. R., Feb 2015, In : Journal of Clinical Endocrinology & Metabolism. 100, 2, p. 483-489 7 p.

    Research output: Contribution to journalArticle

  10. 11β-Hydroxysteroid dehydrogenase type 1 contributes to the balance between 7-keto- and 7-hydroxy-oxysterols in vivo

    Mitic, T., Shave, S., Semjonous, N., McNae, I., Cobice, D. F., Lavery, G. G., Webster, S. P., Hadoke, P. W. F., Walker, B. R. & Andrew, R., 1 Jul 2013, In : Biochemical Pharmacology. 86, 1, p. 146-153 8 p.

    Research output: Contribution to journalArticle

  11. 11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis

    Kipari, T., Hadoke, P. W. F., Iqbal, J., Man, T-Y., Miller, E., Coutinho, A. E., Zhang, Z., Sullivan, K. M., Mitic, T., Livingstone, D. E. W., Schrecker, C., Samuel, K., White, C. I., Bouhlel, M. A., Chinetti-Gbaguidi, G., Staels, B., Andrew, R., Walker, B. R., Savill, J. S., Chapman, K. E. & 1 others, Seckl, J. R., Apr 2013, In : The FASEB Journal. 27, 4, p. 1519-1531 13 p.

    Research output: Contribution to journalArticle

  12. 11β-hydroxysteroid dehydrogenase type 1, brain atrophy and cognitive decline

    MacLullich, A. M. J., Ferguson, K. J., Reid, L. M., Deary, I. J., Starr, J., Wardlaw, J. M., Walker, B. R., Andrew, R. & Seckl, J. R., Jan 2012, In : Neurobiology of Aging. 33, 1, p. 207.e1–207.e8 8 p.

    Research output: Contribution to journalArticle

  13. 19F-magnetic resonance spectroscopy as a tool to quantify 11[beta]-hydroxysteroid dehydrogenase activity in vivo

    Naredo-Gonzalez, G., Jansen, M., Upreti, R., Semple, S., Merrifield, G., Sutcliffe, O., Hansen, M., Marshall, I., Andrew, R. & Walker, B., 2013, In : Endocrine Abstracts. p. 1-1

    Research output: Contribution to journalArticle

  14. 3-DIMENSIONAL EX VIVO ANALYSIS BY OPTICAL PROJECTION TOMOGRAPHY DEMONSTRATES THAT EXOGENOUS GLUCOCORTICOIDS AUGMENT ATHEROGENESIS IN APOE-/- MICE

    Low, L., Kirkby, N. S., Seckl, J. R., Walker, B. R. & Hadoke, P. W. F., 15 Nov 2009, In : Heart. 95, 22, p. - 2 p.

    Research output: Contribution to journalMeeting abstract

  15. 5 alpha-Reductase Type 1 Deficiency or Inhibition Predisposes to Insulin Resistance, Hepatic Steatosis, and Liver Fibrosis in Rodents

    Livingstone, D. E. W., Barat, P., Di Rollo, E. M., Rees, G. A., Weldin, B. A., Rog-Zielinska, E. A., MacFarlane, D. P., Walker, B. R. & Andrew, R., 22 Jan 2015, In : Diabetes . 64, 2, p. 447-458 12 p.

    Research output: Contribution to journalArticle

  16. 5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor

    McInnes, K. J., Kenyon, C. J., Chapman, K. E., Livingstone, D. E. W., Macdonald, L. J., Walker, B. R. & Andrew, R., 2004, In : Journal of Biological Chemistry. 279, 22, p. 22908-12 5 p.

    Research output: Contribution to journalArticle

  17. 5α-Reductase type 1 inhibition or deficiency causes weight gain and insulin resistance in mice and men

    Andrew, R., Upreti, R., Livingstone, D. E. W., Barat, P., Hughes, K. A., MacFarlane, D. P., Gray, C. D., Minns, F. C., Marshall, I., Stewart, L. H. & Walker, B. R., 2013, Association of Physicians Annual Meeting.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  18. 5α-Reductase type 1 modulates insulin sensitivity in men

    Upreti, R., Hughes, K. A., Livingstone, D. E. W., Gray, C. D., Minns, F. C., Macfarlane, D. P., Marshall, I., Stewart, L. H., Walker, B. R. & Andrew, R., Aug 2014, In : Journal of Clinical Endocrinology & Metabolism. 99, 8, p. E1397-E1406 10 p.

    Research output: Contribution to journalArticle

  19. 5α-reduced glucocorticoids exhibit dissociated anti-inflammatory and metabolic effects

    Yang, CHENYING., Nixon, M., Kenyon, C. J., Livingstone, D. E. W., Duffin, R., Rossi, A. G., Walker, B. R. & Andrew, R., 2011, In : British Journal of Pharmacology. 164, 6, p. 1661-71 11 p.

    Research output: Contribution to journalArticle

  20. A choline-deficient diet exacerbates fatty liver but attenuates insulin resistance and glucose intolerance in mice fed a high-fat diet

    Raubenheimer, P. J., Nyirenda, M. J. & Walker, B. R., 2006, In : Diabetes . 55, 7, p. 2015-20 6 p.

    Research output: Contribution to journalArticle

  21. A combination of polymorphisms in HSD11B1 associates with in vivo 11{beta}-HSD1 activity and metabolic syndrome in women with and without polycystic ovary syndrome

    Gambineri, A., Tomassoni, F., Munarini, A., Stimson, R. H., Mioni, R., Pagotto, U., Chapman, K. E., Andrew, R., Mantovani, V., Pasquali, R. & Walker, B. R., 2011, In : European Journal of Endocrinology. 165, 2, p. 283-92 10 p.

    Research output: Contribution to journalArticle

  22. A history of previous gestational diabetes mellitus is associated with adverse changes in insulin secretion and VLDL metabolism independently of increased intrahepatocellular lipid

    Forbes, S., Godsland, I. F., Taylor-Robinson, S. D., Bell, J. D., Thomas, E. L., Patel, N., Hamilton, G., Parker, K. H., Marshall, I., Gray, C. D., Bedford, D., Caslake, M., Walker, B. R. & Johnston, D. G., Sep 2013, In : Diabetologia. 56, 9, p. 2021-2033 13 p.

    Research output: Contribution to journalArticle

  23. A poorer metabolic profile in subjects with early psychosis is associated with a distinct diurnal pattern in salivary cortisol

    Ortega, L., Monseny, R., Lopez, X., Duch, M., Valero, J., Franch, J., Walker, B. R., Reynolds, R. M. & Labad, J., Sep 2011, In : European Neuropsychopharmacology. 21, p. S461-S462 2 p.

    Research output: Contribution to journalMeeting abstract

  24. ATHEROPROTECTION BY 11B-HSD1 INHIBITION IN APOLIPOPROTEIN E KNOCKOUT MICE IS ASSOCIATED WITH LOWERING OF BLOOD PRESSURE

    Iqbal, J., Sullivan, K., Livingstone, D. E., Andrew, R., Walker, B. R. & Hadoke, P. W. F., Jun 2009, In : Heart. 95, p. A61-A61 1 p.

    Research output: Contribution to journalArticle

  25. Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance

    Andrews, R. C., Herlihy, O., Livingstone, D. E. W., Andrew, R. & Walker, B. R., 2002, In : Journal of Clinical Endocrinology & Metabolism. 87, 12, p. 5587-93 7 p.

    Research output: Contribution to journalArticle

  26. Accounting for fluctuations in a lattice model of microemulsions

    Dawson, K. A., Walker, B. L. & Berera, A., 1 Jun 1990, In : Physica a-Statistical mechanics and its applications. 165, 3, p. 320-351 32 p.

    Research output: Contribution to journalArticle

  27. Activation of the Hypothalamic-Pituitary-Adrenal Axis in Adults With Mineralocorticoid Receptor Haploinsufficiency

    Walker, B. R., Andrew, R., Escoubet, B. & Zennaro, M-C., Aug 2014, In : Journal of Clinical Endocrinology & Metabolism. 99, 8, p. E1586-E1591 6 p.

    Research output: Contribution to journalArticle

  28. Acute effects of glucocorticoids on endothelial fibrinolytic and vasodilator function in humans

    Dover, A. R., Hadoke, P. W. F., Walker, B. R. & Newby, D. E., 2007, In : Journal of cardiovascular pharmacology. 50, 3, p. 321-6 6 p.

    Research output: Contribution to journalArticle

  29. Acute in vivo regulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by insulin and intralipid infusions in humans

    Wake, D. J., Homer, N. Z. M., Andrew, R. & Walker, B. R., 2006, In : Journal of Clinical Endocrinology & Metabolism. 91, 11, p. 4682-8 7 p.

    Research output: Contribution to journalArticle

  30. Acute interaction between hydrocortisone and insulin alters the plasma metabolome in humans

    Alwashih, M. A., Stimson, R., Andrew, R., Walker, B. & Watson, D. G., 13 Sep 2017, In : Scientific Reports.

    Research output: Contribution to journalArticle

  31. Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct

    Stimson, R. H., Anderson, A. J., Lynne, R., Macfarlane, D. P., de Beaux, A. C., Mole, D. J., Andrew, R. & Walker, B. R., 8 Feb 2017, In : Diabetes Obesity & Metabolism.

    Research output: Contribution to journalArticle

  32. Adrenal insufficiency in patients on long-term opioid analgesia

    Gibb, F. W., Stewart, A., Walker, B. R. & Strachan, M. W. J., 4 Jun 2016, In : Clinical Endocrinology.

    Research output: Contribution to journalArticle

  33. Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome - Nested case-control study

    Brunner, E. J., Hemingway, H., Walker, B. R., Page, M., Clarke, P., Juneja, M., Shipley, M. J., Kumari, M., Andrew, R., Seckl, J. R., Papadopoulos, A., Checkley, S., Rumley, A., Lowe, G. D. O., Stansfeld, S. A. & Marmot, M. G., 19 Nov 2002, In : Circulation. 106, 21, p. 2659-2665 7 p.

    Research output: Contribution to journalArticle

  34. Altered control of cortisol secretion in adult men with low birth weight and cardiovascular risk factors

    Reynolds, R. M., Walker, B. R., Syddall, H. E., Andrew, R., Wood, P. J., Whorwood, C. B. & Phillips, D. I., 2001, In : Journal of Clinical Endocrinology & Metabolism. 86, 1, p. 245-50 6 p.

    Research output: Contribution to journalArticle

  35. Altered peripheral sensitivity to glucocorticoids in primary open-angle glaucoma

    Stokes, J., Walker, B. R., Campbell, J. C., Seckl, J. R., O'Brien, C. & Andrew, R., Dec 2003, In : Investigative Ophthalmology & Visual Science. 44, 12, p. 5163-5167 5 p.

    Research output: Contribution to journalArticle

  36. Altered vascular contractility in adult female rats with hypertension programmed by prenatal glucocorticoid exposure

    Hadoke, P. W. F., Lindsay, R. S., Seckl, J. R., Walker, B. R. & Kenyon, C. J., Mar 2006, In : Journal of Endocrinology. 188, 3, p. 435-442 8 p.

    Research output: Contribution to journalArticle

  37. Apparent cortisone reductase deficiency: a functional defect in 11beta-hydroxysteroid dehydrogenase type 1

    Jamieson, A., Wallace, A. M., Andrew, R., Nunez, B. S., Walker, B. R., Fraser, R., White, P. C. & Connell, J. M., 1999, In : Journal of Clinical Endocrinology & Metabolism. 84, 10, p. 3570-4 5 p.

    Research output: Contribution to journalArticle

  38. Aromatase Inhibition Reduces Insulin Sensitivity in Healthy Men

    Gibb, F. W., Homer, N. Z. M., Faqehi, A. M. M., Upreti, R., Livingstone, D. E., Mcinnes, K. J., Andrew, R. & Walker, B. R., 11 Mar 2016, In : Journal of Clinical Endocrinology & Metabolism. p. jc.2015-4146

    Research output: Contribution to journalArticle

  39. Bile acids modulate glucocorticoid metabolism and the hypothalamic-pituitary-adrenal axis in obstructive jaundice

    McNeilly, A. D., Macfarlane, D. P., O'Flaherty, E., Livingstone, D. E., Mitić, T., McConnell, K. M., McKenzie, S. M., Davies, E., Reynolds, R. M., Thiesson, H. C., Skøtt, O., Walker, B. R. & Andrew, R., May 2010, In : Journal of Hepatology. 52, 5, p. 705-711 7 p.

    Research output: Contribution to journalArticle

  40. Body fat distribution and cortisol metabolism in healthy men: Enhanced 5 beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver

    Westerbacka, J., Yki-Jarvinen, H., Vehkavaara, S., Hakkinen, A. M., Andrew, R., Wake, D. J., Seckl, J. R. & Walker, B. R., 1 Oct 2003, In : Journal of Clinical Endocrinology & Metabolism. 88, 10, p. 4924-4931 8 p.

    Research output: Contribution to journalArticle

  41. Can cortisol predict the future in obesity?

    Reynolds, R. M. & Walker, B. R., 2007, In : Clinical Endocrinology. 67, 1, p. 1-2 2 p.

    Research output: Contribution to journalArticle

  42. Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity

    Morgan, R. A., Beck, K. R., Nixon, M., Homer, N. Z. M., Crawford, A. A., Melchers, D., Houtman, R., Meijer, O. C., Stomby, A., Anderson, A. J., Upreti, R., Stimson, R. H., Olsson, T., Michoel, T., Cohain, A., Ruusalepp, A., Schadt, E. E., Björkegren, J. L. M., Andrew, R., Kenyon, C. J. & 4 others, Hadoke, P. W. F., Odermatt, A., Keen, J. A. & Walker, B. R., 6 Sep 2017, In : Scientific Reports. 7, 1, 10633.

    Research output: Contribution to journalArticle

  43. Circulating plasma cortisol concentrations are not associated with coronary artery disease or peripheral vascular disease

    Reynolds, R. M., Ilyas, B., Price, J. F., Fowkes, F. G. R., Newby, D. E., Webb, D. J. & Walker, B. R., Jul 2009, In : QJM: An International Journal of Medicine. 102, 7, p. 469-475 7 p.

    Research output: Contribution to journalArticle

  44. Clinical research: developing an appropriate career structure

    Mellanby, R. J., Price, J., Wooldridge, L., Jonsson, N. N., Clegg, P. D., Emes, R. D., England, G., Corr, S. A., Piercy, R. J., Mulcahy, G., Wood, J. L., Walker, B. R. & Argyle, D. J., 28 Nov 2015, In : Veterinary Record. 177, 21, p. 544-7 4 p.

    Research output: Contribution to journalArticle

  45. Combined Receptor Antagonist Stimulation of the Hypothalamic-Pituitary-Adrenal Axis Test Identifies Impaired Negative Feedback Sensitivity to Cortisol in Obese Men

    Mattsson, C., Reynolds, R. M., Simonyte, K., Olsson, T. & Walker, B. R., Apr 2009, In : Journal of Clinical Endocrinology & Metabolism. 94, 4, p. 1347-1352 6 p.

    Research output: Contribution to journalArticle

  46. Contrasting effects of intrauterine growth retardation and premature delivery on adult cortisol secretion and metabolism in man

    Walker, B. R., Irving, R. J., Andrew, R. & Belton, N. R., 2002, In : Clinical Endocrinology. 57, 3, p. 351-5 5 p.

    Research output: Contribution to journalArticle

  47. Contribution of Endogenous Glucocorticoids and Their Intravascular Metabolism by 11β-HSDs to Postangioplasty Neointimal Proliferation in Mice

    Iqbal, J., Macdonald, L. J., Low, L., Seckl, J. R., Yau, C. W., Walker, B. R. & Hadoke, P. W. F., Dec 2012, In : Endocrinology . 153, 12, p. 5896-5905 10 p.

    Research output: Contribution to journalArticle

  48. Controlling cortisol's contribution to degenerative disease

    Walker, B. R., Nov 2015, In : Psychoneuroendocrinology. 61, p. 1

    Research output: Contribution to journalMeeting abstract

  49. Cortisol Inactivation by 11 beta-Hydroxysteroid dehydrogenase-2 May Enhance Endometrial Angiogenesis via Reduced Thrombospondin-1 in Heavy Menstruation

    Rae, M., Mohamad, A., Price, D., Hadoke, P. W. F., Walker, B. R., Mason, J. I., Hillier, S. G., Critchley, H. O. D. & Mason, J. I., Apr 2009, In : Journal of Clinical Endocrinology & Metabolism. 94, 4, p. 1443-1450 8 p.

    Research output: Contribution to journalArticle

  50. Cortisol Release From Adipose Tissue by 11 beta-Hydroxysteroid Dehydrogenase Type 1 in Humans

    Stimson, R. H., Andersson, J., Andrew, R., Redhead, D. N., Karpe, F., Hayes, P. C., Olsson, T. & Walker, B. R., Jan 2009, In : Diabetes . 58, 1, p. 46-53 8 p.

    Research output: Contribution to journalArticle

  51. Cortisol metabolism in healthy young adults: sexual dimorphism in activities of A-ring reductases, but not 11beta-hydroxysteroid dehydrogenases

    Finken, M. J., Andrews, R. C., Andrew, R. & Walker, B. R., 1999, In : Journal of Clinical Endocrinology & Metabolism. 84, 9, p. 3316-21 6 p.

    Research output: Contribution to journalArticle

  52. Cortisol metabolism in type 2 diabetes

    Walker, B. R. & Andrew, R., Jun 2003, In : Journal of Clinical Endocrinology & Metabolism. 88, 6, p. 2951-2952 2 p.

    Research output: Contribution to journalLetter

  53. Cortisol secretion and rate of bone loss in a population-based cohort of elderly men and women

    Reynolds, R. M., Dennison, E. M., Walker, B. R., Syddall, H. E., Wood, P. J., Andrew, R., Phillips, D. I. & Cooper, C., 2005, In : Calcified Tissue International. 77, 3, p. 134-8 5 p.

    Research output: Contribution to journalArticle

  54. Cortisol--cause and cure for metabolic syndrome?

    Walker, B. R., 2006, In : Diabetic Medicine. 23, 12, p. 1281-8 8 p.

    Research output: Contribution to journalArticle

  55. Current management, morbidity and genotype-phenotype correlation in adults with congenital adrenal hyperplasia - analysis of the United Kingdom congenital adrenal hyperplasia adult study executive (CaHASE) cohort

    Krone, N., Willis, D. S., Rose, I. T., Crosby, C., Wild, S. H., Doherty, E. J., Hahner, S., Han, T. S., Stimson, R. H., Carroll, P. V., Conway, G. S., Rees, D. A., Walker, B. R., MacDonald, F., Ross, R. J., Arlt, W. & United Kingdom Congenital Adrenal, 2009, In : Hormone Research. 72, p. 41-41 1 p.

    Research output: Contribution to journalMeeting abstract

  56. Decreased maternal hypothalamic-pituitary-adrenal axis activity in very severely obese pregnancy: Associations with birthweight and gestation at delivery

    Stirrat, L. I., O'Reilly, J. R., Barr, S. M., Andrew, R., Riley, S. C., Howie, A. F., Bowman, M., Smith, R., Lewis, J. G., Denison, F. C., Forbes, S., Seckl, J. R., Walker, B. R., Norman, J. E. & Reynolds, R. M., 25 Sep 2015, In : Psychoneuroendocrinology. 63, p. 135-143 9 p.

    Research output: Contribution to journalArticle

  57. Development of a Bayesian response-adaptive trial design for the Dexamethasone for Excessive Menstruation study

    Holm Hansen, C., Warner, P., Parker, R. A., Walker, B. R., Critchley, H. O. D. & Weir, C. J., 1 Dec 2017, In : Statistical Methods in Medical Research.

    Research output: Contribution to journalArticle

  58. Development of a derivatisation method for the analysis of aldehyde modified amino acid residues in proteins by Fourier transform mass spectrometry

    Pournamdari, M., Saadi, A., Ellis, E., Andrew, R., Walker, B. & Watson, D. G., 9 Feb 2009, In : Analytica Chimica Acta. 633, 2, p. 216-222 7 p.

    Research output: Contribution to journalArticle

  59. Development-related increase in cortisol biosynthesis by human granulosa cells

    Yong, P. Y., Thong, K. J., Andrew, R., Walker, B. R. & Hillier, S. G., 2000, In : Journal of Clinical Endocrinology & Metabolism. 85, 12, p. 4728-33 6 p.

    Research output: Contribution to journalArticle

  60. Diet and Physical Activity in Severely Obese Pregnancy: Associations with Gestational Weight Gain and Birthweight

    Mohd-Shukri, N. A., Bolton, J., Forbes, S., Denison, F. C., Norman, J. E., Walker, B. R. & Reynolds, R. M., Sep 2011, In : Journal of Developmental Origins of Health and Disease. 2, p. S93-S93 1 p.

    Research output: Contribution to journalMeeting abstract

  61. Diet-induced weight loss has chronic tissue-specific effects on glucocorticoid metabolism in overweight postmenopausal women

    Stomby, A., Simonyte, K., Mellberg, C., Ryberg, M., Stimson, R. H., Larsson, C., Lindahl, B., Andrew, R., Walker, B. R. & Olsson, T., May 2015, In : International Journal of Obesity. 39, 5, p. 814-9 6 p.

    Research output: Contribution to journalArticle

  62. Dietary macronutrient content alters cortisol metabolism independently of body weight changes in obese men

    Stimson, R. H., Johnstone, A. M., Homer, N. Z. M., Wake, D. J., Morton, N. M., Andrew, R., Lobley, G. E. & Walker, B. R., 2007, In : Journal of Clinical Endocrinology & Metabolism. 92, 11, p. 4480-4 5 p.

    Research output: Contribution to journalArticle

  63. Differences in cortisol concentrations in South Asian and European men living in the United Kingdom

    Reynolds, R. M., Fischbacher, C., Bhopal, R., Byrne, C. D., White, M., Unwin, N. & Walker, B. R., 2006, In : Clinical Endocrinology. 64, 5, p. 530-4 5 p.

    Research output: Contribution to journalArticle

  64. Differential Effects of Abdominal Adipose Tissue Distribution on Insulin Sensitivity in Black and White South African Women

    Goedecke, J. H., Levitt, N. S., Lambert, E. V., Utzschneider, K. M., Faulenbach, M. V., Dave, J. A., West, S., Victor, H., Evans, J., Olsson, T., Walker, B. R., Seckl, J. R. & Kahn, S. E., Aug 2009, In : Obesity. 17, 8, p. 1506-1512 7 p.

    Research output: Contribution to journalArticle

  65. Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors

    Webster, S. P., Ward, P., Binnie, M., Craigie, E., McConnell, K. M. M., Sooy, K., Vinter, A., Seckl, J. R. & Walker, B. R., 15 May 2007, In : Bioorganic & Medicinal Chemistry Letters. 17, 10, p. 2838-2843 6 p.

    Research output: Contribution to journalArticle

  66. Displacement of Cortisol From Human Heart by Acute Administration of a Mineralocorticoid Receptor Antagonist

    Iqbal, J., Andrew, R., Cruden, N. L., Kenyon, C. J., Hughes, K. A., Newby, D. E., Hadoke, P. W. F. & Walker, B. R., Mar 2014, In : Journal of Clinical Endocrinology & Metabolism. 99, 3, p. 915-922 8 p.

    Research output: Contribution to journalArticle

  67. Distinguishing the activities of 11beta-hydroxysteroid dehydrogenases in vivo using isotopically labeled cortisol

    Andrew, R., Smith, K., Jones, G. C. & Walker, B. R., 2002, In : Journal of Clinical Endocrinology & Metabolism. 87, 1, p. 277-85 9 p.

    Research output: Contribution to journalArticle

  68. Dysregulation of glucocorticoid metabolism in murine obesity: comparable effects of leptin resistance and deficiency

    Livingstone, D. E. W., Grassick, S. L., Currie, G. L., Walker, B. R. & Andrew, R., May 2009, In : Journal of Endocrinology. 201, 2, p. 211-8 8 p.

    Research output: Contribution to journalArticle

  69. ECAT-V: where clinical and research training meet

    Argyle, D. J., Iredale, J. P., Jackson, A. P. & Walker, B. R., 19 Oct 2013, In : Veterinary Record. 173, 15, p. 364-5 2 p.

    Research output: Contribution to journalArticle

  70. EFFECT OF INTRACELLULAR GLUCOCORTICOID METABOLISM ON NEOINTIMAL PROLIFERATION IN A MOUSE MODEL OF WIRE ANGIOPLASTY

    Iqbal, J., Macdonald, L. J., Yau, C. W., Walker, B. R. & Hadoke, P. W. F., Oct 2011, In : Heart. 97, 20, p. 1-1 1 p.

    Research output: Contribution to journalMeeting abstract

  71. Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial

    Chiswick, C., Reynolds, R. M., Denison, F., Drake, A. J., Forbes, S., Newby, D. E., Walker, B. R., Quenby, S., Wray, S., Weeks, A., Lashen, H., Rodriguez, A., Murray, G., Whyte, S. & Norman, J. E., Oct 2015, In : The Lancet Diabetes and Endocrinology.

    Research output: Contribution to journalArticle

  72. Effects of Proportions of Dietary Macronutrients on Glucocorticoid Metabolism in Diet-Induced Obesity in Rats

    Stimson, R. H., Lobley, G. E., Maraki, I., Morton, N. M., Andrew, R. & Walker, B. R., 19 Jan 2010, In : PLoS ONE. 5, 1, p. - 7 p., e8779.

    Research output: Contribution to journalArticle

  73. Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with type 2 diabetes with and without fatty liver

    Macfarlane, D. P., Raubenheimer, P. J., Preston, T., Gray, C. D., Bastin, M. E., Marshall, I., Iredale, J. P., Andrew, R. & Walker, B. R., 1 Oct 2014, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 307, 7, p. G760-768 9 p.

    Research output: Contribution to journalArticle

  74. Effects of gonadectomy on glucocorticoid metabolism in obese Zucker rats

    Barat, P., Livingstone, D. E. W., Elferink, C. M. C., McDonnell, C. R., Walker, B. R. & Andrew, R., 2007, In : Endocrinology . 148, 10, p. 4836-43 8 p.

    Research output: Contribution to journalArticle

  75. Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men

    Wake, D. J., Stimson, R. H., Tan, G. D., Homer, N. Z. M., Andrew, R., Karpe, F. & Walker, B. R., 2007, In : Journal of Clinical Endocrinology & Metabolism. 92, 5, p. 1848-56 9 p.

    Research output: Contribution to journalArticle

  76. Efficacy of metformin in pregnant obese women: a randomised controlled trial

    Chiswick, C. A., Reynolds, R. M., Denison, F. C., Whyte, S. A., Drake, A. J., Newby, D. E., Walker, B. R., Forbes, S., Murray, G. D., Quenby, S., Wray, S. & Norman, J. E., 14 Jan 2015, In : BMJ Open. 5, 1, p. e006854

    Research output: Contribution to journalArticle

  77. Elevated Fasting Plasma Cortisol Is Associated with Ischemic Heart Disease and Its Risk Factors in People with Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study

    Reynolds, R. M., Labad, J., Strachan, M. W. J., Braun, A., Fowkes, F. G. R., Lee, A. J., Frier, B. M., Seckl, J. R., Walker, B. R., Price, J. F. & ET2DS Investigators, Apr 2010, In : Journal of Clinical Endocrinology & Metabolism. 95, 4, p. 1602-1608 7 p.

    Research output: Contribution to journalArticle

  78. Elevated hepatic 11β-hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia

    Chapagain, A., Caton, P. W., Kieswich, J., Andrikopoulos, P., Nayuni, N., Long, J. H., Harwood, S. M., Webster, S. P., Raftery, M. J., Thiemermann, C., Walker, B. R., Seckl, J. R., Corder, R. & Yaqoob, M. M., 11 Mar 2014, In : Proceedings of the National Academy of Sciences (PNAS). 111, 10, p. 3817-22 6 p.

    Research output: Contribution to journalArticle

  79. Elevated plasma cortisol concentrations: A link between low birth weight and the insulin resistance syndrome?

    Phillips, D. I. W., Barker, D. J. P., Fall, C. H. D., Seckl, J. R., Whorwood, C. B., Wood, P. J. & Walker, B. R., Mar 1998, In : Journal of Clinical Endocrinology & Metabolism. 83, 3, p. 757-760 4 p.

    Research output: Contribution to journalArticle

  80. Endothelial cell dysfunction in mice after transgenic knockout of type 2, but not type 1, 11 beta-hydromysteroid dehydrogenase

    Hadoke, P. W. F., Christy, C., Kotelevtsev, Y. V., Williams, B. C., Kenyon, C. J., Seckl, J. R., Mullins, J. J. & Walker, B. R., 4 Dec 2001, In : Circulation. 104, 23, p. 2832-2837 6 p.

    Research output: Contribution to journalArticle

  81. Endothelium-derived hyperpolarizing factor and potassium use different mechanisms to induce relaxation of human subcutaneous resistance arteries

    McIntyre, C. A., Buckley, C. H., Jones, G. C., Sandeep, T. C., Andrews, R. C., Elliott, A. I., Gray, G. A., Williams, B. C., McKnight, J. A., Walker, B. R. & Hadoke, P. W., 2001, In : British Journal of Pharmacology. 133, 6, p. 902-8 7 p.

    Research output: Contribution to journalArticle

  82. Estrogens protect male mice from obesity complications and influence glucocorticoid metabolism

    Dakin, R. S., Walker, B., Seckl, J. R., Hadoke, P. W. F. & Drake, A. J., 30 Jun 2015, In : International Journal of Obesity.

    Research output: Contribution to journalArticle

  83. Evaluation of an FFQ to assess total energy and nutrient intakes in severely obese pregnant women

    Mohd-Shukri, N. A., Bolton, J. L., Norman, J. E., Walker, B. R. & Reynolds, R. M., Aug 2013, In : Public Health Nutrition. 16, 8, p. 1427-1435 9 p.

    Research output: Contribution to journalArticle

  84. Exogenous Glucocorticoids Inhibit Neointimal Proliferation but Increase Local Thrombosis in Mice

    Low, L., Seckl, J. R., Walker, B. R. & Hadoke, P. W., Nov 2010, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 11, p. E260-E260 1 p.

    Research output: Contribution to journalMeeting abstract

  85. Exogenous, but Not Endogenous, Glucocorticoids Augment Atherosclerosis in Mice

    Low, L., Kirkby, N. S., Seckl, J. R., Walker, B. R. & Hadoke, P. W., Nov 2010, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 11, p. E291-E291 1 p.

    Research output: Contribution to journalMeeting abstract

  86. Extra-Adrenal Cortisol Production in Obese Men with Type Two Diabetes Mellitus - How Big Is the Therapeutic Target for 11 beta HSD1 Inhibitors?

    Stimson, R. H., Andrew, R., McAvoy, N. C., Tripathi, D., Hayes, P. C. & Walker, B. R., Jun 2010, In : Endocrine Reviews. 31, 3, p. S11-S11 1 p.

    Research output: Contribution to journalMeeting abstract

  87. Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning

    Walker, B. R., 2007, In : Proceedings of the Nutrition Society. 66, 1, p. 1-8 8 p.

    Research output: Contribution to journalArticle

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