Edinburgh Research Explorer

Prof Brian Walker

(Former employee or visitor)

  1. 2019
  2. Heritability of cortisol production and metabolism throughout adolescence: a twin study

    van Keulen, B. J., Dolan, C. V., Andrew, R., Walker, B., Hulshoff Pol, H. E., Boomsma, D. I., Rotteveel, J. & finken, M. JJ., 14 Oct 2019, In : Journal of Clinical Endocrinology & Metabolism.

    Research output: Contribution to journalArticle

  3. Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study

    Wei, L., Chia-Cheng Lai, E., Kao-Yang, Y-H., Walker, B., MacDonald, T. M. & Andrew, R., 10 Apr 2019, In : BMJ. 365.

    Research output: Contribution to journalArticle

  4. Higher Insulin Resistance and Adiposity in Postmenopausal Women With Breast Cancer Treated With Aromatase Inhibitors

    Gibb, F., Dixon, M. J., Clarke, C., Homer, N., Faqehi, A., Andrew, R. & Walker, B., 28 Mar 2019, In : Journal of Clinical Endocrinology & Metabolism. 104, 9, p. 3670–3678

    Research output: Contribution to journalArticle

  5. 2018
  6. Species-specific regulation of angiogenesis by glucocorticoids reveals contrasting effects on inflammatory and angiogenic pathways

    Morgan, R., Keen, J., Halligan, D., O'Callaghan, A., Andrew, R., Livingstone, D., Livingstone, D., Abernethie, A., Maltese, G., Walker, B. & Hadoke, P., 15 Feb 2018, In : PLoS ONE. 13, 2, p. e0192746

    Research output: Contribution to journalArticle

  7. 2017
  8. Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia

    Alwashih, M. A., Watson, D. G., Andrew, R., Stimson, R. H., Alossaimi, M., Blackburn, G. & Walker, B. R., 6 Dec 2017, In : Scientific Reports. 7, 1, p. 17092

    Research output: Contribution to journalArticle

  9. Gas chromatography tandem mass spectrometry offers advantages for urinary steroids analysis

    Homer, N., Kothiya, S., Rutter, A., Walker, B. & Andrew, R., Dec 2017, In : Analytical Biochemistry. 538

    Research output: Contribution to journalArticle

  10. Hair cortisol in twins: Heritability and genetic overlap with psychological variables and stress-system genes

    Rietschel, L., Streit, F., Zhu, G., McAloney, K., Frank, J., Couvy-Duchesne, B., Witt, S. H., Binz, T., McGrath, J. J., Hickie, I. B., Hansell, N. K., Wright, M. J., Gillespie, N., Forstner, A. J., Schulze, T. G., Wust, S., Nöthen, M. M., Baumgartner, M., Walker, B., Crawford, A. & 4 others, Colodro-Conde, L., Medland, S. E., Martin, N. G. & Rietschel, M., 10 Nov 2017, In : Scientific Reports.

    Research output: Contribution to journalArticle

  11. The low single nucleotide polymorphism heritability of plasma and saliva cortisol levels

    Neumann, A., Direk, N., Crawford, A. A., Mirza, S., Adams, H., Bolton, J., Hayward, C., Strachan, D. P., Payne, E. K., Smith, J. A., Milaneschi, Y., Penninx, B., Hottenga, J. J., de Geus, E., Oldehinkel, A. J., van der Most, P. J., de Rijke, Y., Walker, B. R. & Tiemeier, H., Nov 2017, In : Psychoneuroendocrinology. 85, p. 88-95 8 p.

    Research output: Contribution to journalArticle

  12. Acute interaction between hydrocortisone and insulin alters the plasma metabolome in humans

    Alwashih, M. A., Stimson, R., Andrew, R., Walker, B. & Watson, D. G., 13 Sep 2017, In : Scientific Reports.

    Research output: Contribution to journalArticle

  13. Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity

    Morgan, R. A., Beck, K. R., Nixon, M., Homer, N. Z. M., Crawford, A. A., Melchers, D., Houtman, R., Meijer, O. C., Stomby, A., Anderson, A. J., Upreti, R., Stimson, R. H., Olsson, T., Michoel, T., Cohain, A., Ruusalepp, A., Schadt, E. E., Björkegren, J. L. M., Andrew, R., Kenyon, C. J. & 4 others, Hadoke, P. W. F., Odermatt, A., Keen, J. A. & Walker, B. R., 6 Sep 2017, In : Scientific Reports. 7, 1, p. 10633

    Research output: Contribution to journalArticle

  14. 11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI

    Mylonas, K. J., Turner, N. A., Bageghni, S. A., Kenyon, C. J., White, C. I., McGregor, K., Kimmitt, R. A., Sulston, R., Kelly, V., Walker, B. R., Porter, K. E., Chapman, K. E. & Gray, G. A., 1 Jun 2017, In : Journal of Endocrinology. 233, 3, p. 315-327 13 p.

    Research output: Contribution to journalArticle

  15. Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

    Tachmazidou, I., Süveges, D., Min, J. L., Ritchie, G. R. S., Steinberg, J., Walter, K., Iotchkova, V., Schwartzentruber, J., Huang, J., Memari, Y., Mccarthy, S., Crawford, A. A., Bombieri, C., Cocca, M., Farmaki, A., Gaunt, T. R., Jousilahti, P., Kooijman, M. N., Lehne, B., Malerba, G. & 83 others, Männistö, S., Matchan, A., Medina-gomez, C., Metrustry, S. J., Nag, A., Ntalla, I., Paternoster, L., Rayner, N. W., Sala, C., Scott, W. R., Shihab, H. A., Southam, L., St Pourcain, B., Traglia, M., Trajanoska, K., Zaza, G., Zhang, W., Artigas, M. S., Bansal, N., Benn, M., Chen, Z., Danecek, P., Lin, W., Locke, A., Luan, J., Manning, A. K., Mulas, A., Sidore, C., Tybjaerg-hansen, A., Varbo, A., Zoledziewska, M., Finan, C., Hatzikotoulas, K., Hendricks, A. E., Kemp, J. P., Moayyeri, A., Panoutsopoulou, K., Szpak, M., Wilson, S. G., Boehnke, M., Cucca, F., Di Angelantonio, E., Langenberg, C., Lindgren, C., Mccarthy, M. I., Morris, A. P., Nordestgaard, B. G., Scott, R. A., Tobin, M. D., Wareham, N. J., Burton, P., Chambers, J. C., Smith, G. D., Dedoussis, G., Felix, J. F., Franco, O. H., Gambaro, G., Gasparini, P., Hammond, C. J., Hofman, A., Jaddoe, V. W. V., Kleber, M., Kooner, J. S., Perola, M., Relton, C., Ring, S. M., Rivadeneira, F., Salomaa, V., Spector, T. D., Stegle, O., Toniolo, D., Uitterlinden, A. G., Barroso, I., Greenwood, C. M. T., Perry, J. R. B., Walker, B. R., Butterworth, A. S., Xue, Y., Durbin, R., Small, K. S., Soranzo, N., Timpson, N. J. & Zeggini, E., 1 Jun 2017, In : American Journal of Human Genetics. 100, 6, p. 865-884

    Research output: Contribution to journalArticle

  16. Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™)

    Webster, S. P., McBride, A., Binnie, M., Sooy, K., Seckl, J. R., Andrew, R., Pallin, T. D., Hunt, H. J., Perrior, T. R., Ruffles, V. S., Ketelbey, J. W., Boyd, A. & Walker, B. R., Mar 2017, In : British Journal of Pharmacology.

    Research output: Contribution to journalArticle

  17. Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct

    Stimson, R., Anderson, A. J., Lynne, R., Macfarlane, D. P., de Beaux, A. C., Mole, D., Andrew, R. & Walker, B., 8 Feb 2017, In : Diabetes Obesity & Metabolism.

    Research output: Contribution to journalArticle

  18. Safer topical treatment for inflammation using 5α-tetrahydrocorticosterone in mouse models

    Gastaldello, A., Livingstone, D. E. W., Abernethie, A. J., Tsang, N., Walker, B. R., Hadoke, P. W. F. & Andrew, R., 24 Jan 2017, In : Biochemical Pharmacology. 129, p. 73–84

    Research output: Contribution to journalArticle

  19. Inhibition or deletion of 11Β-HSD1 does not increase angiogenesis in ischemic retinopathy

    Davidson, C. T., Dover, A. R., McVicar, C. M., Megaw, R., Glenn, J. V., Hadoke, P. W. F., Stitt, A. W. & Walker, B. R., 11 Jan 2017, In : Diabetes and Metabolism.

    Research output: Contribution to journalArticle

  20. Metabolic dysfunction in female mice with disruption of 5α-reductase 1

    Livingstone, D., Di Rollo, E. M., Mak, T. C-S., Sooy, K., Walker, B. & Andrew, R., Jan 2017, In : Journal of Endocrinology. 232, 1, p. 29-36

    Research output: Contribution to journalArticle

  21. 2016
  22. Vascular Dysfunction in Horses with Endocrinopathic Laminitis

    Morgan, R. A., Keen, J. A., Walker, B. R. & Hadoke, P. W. F., 29 Sep 2016, In : PLoS ONE. 11, 9, e0163815.

    Research output: Contribution to journalArticle

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