Edinburgh Research Explorer

Chengcan Yao

Reader

Phone: 0131 242 6685

Willingness to take PhD students: Yes

To study the role of bioactive lipids (especially prostaglandins) in inflammatory diseases.

Biography

Chengcan Yao received his PhD in Biomedical Science from Kyoto University at 2010. He then did his post-doc with Professor Shuh Narumiya at Kyoto University as a JSPS (Japan Society for the Promotion of Science) Research Fellow for Overseas Researchers. From 2013, Chengcan established his independent research at the MRC Centre for Inflammation Research (CIR) in the University of Edinburgh as a Chancellor's Fellowship.

Qualifications

BSc, MSc, PhD

Websites

http://www.cir.ed.ac.uk/investigator/Dr-Chengcan-Yao

Current Research Interests

Bioactive lipids in inflammation and immunity

Collaborative Activity

Prof Shuh Narumiya (Kyoto Univ), Prof Richard Breyer (Vanderbilt Univ), Rick Maizels (Glasgow Univ) and many groups within the University of Edinburgh

Research students

PhD student

Teaching

Honour student mini projects, C1&H3A Wikis

Office Hours

9am-5pm, Mon-Fri

Highlighted research outputs

  1. Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis

    Research output: Contribution to journal › Article › peer-review

  2. T cell–intrinsic prostaglandin E2-EP2/EP4 signaling is critical in pathogenic TH17 cell–driven inflammation

    Research output: Contribution to journal › Article › peer-review

  3. Facilitation of IL-22 production from innate lymphoid cells by prostaglandin E2 prevents experimental lung neutrophilic inflammation

    Research output: Contribution to journal › Letter › peer-review

  4. Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells

    Research output: Contribution to journal › Article › peer-review

  5. Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell–IL-22 axis

    Research output: Contribution to journal › Article › peer-review

View all (18) »

Research projects

  1. Single cell definition of the mechanistic role of kynurenine monooxygenase at the innate immune interface in acute pancreatitis.

    Project: Research

  2. Defining a specific IL-22-mediated pathway in regulating eczema

    Project: Research

  3. Investigating the immune mechanisms underlying NSAID chemoprevention of colorectal cancer

    Project: Research

View all (4) »

Research press coverage

  1. Dr Chengcan Yao shows how the gut keeps deadly infections at bay

    Press/Media: Research

View all (1) »

ID: 7481152