Edinburgh Research Explorer

Prof David Newby

BHF Duke of Edinburgh Chair of Cardiology

  1. 2019
  2. A novel CT-based radiotranscriptomic signature of perivascular fat improves cardiac risk prediction

    Oikonomou, E. K., Williams, M., Kotanidis, C. P., Desai, M. Y., Marwan, M., Antonopoulos, A. S., Thomas, K. E., Thomas, S., Akoumianakis, I., Fan, L. M., Kesavan, S., Herdman, L., Alashi, A., Centeno, E. H., Lyasheva, M., Griffin, B. P., Flamm, S. D., Shirodaria, C., Sabharwal, N., Kelion, A. & 9 othersDweck, M., van Beek, E., Deanfield, J. E., Hopewell, J. C., Neubauer, S., Channon, K. M., Achenbach, S., Newby, D. & Antoniades, C., 3 Sep 2019, In : European Heart Journal.

    Research output: Contribution to journalArticle

  3. High-sensitivity troponin and the application of risk stratification thresholds in patients with suspected acute coronary syndrome

    High-STEACS Investigators, Bularga, A., Lee, K., Stewart, S., Ferry, A., Chapman, A., Marshall, L., Strachan, F., Cruickshank, A., Maguire, D., Berry, C., Findlay, I., Shah, A., Newby, D., Mills, N. & Anand, A., 1 Sep 2019, In : Circulation.

    Research output: Contribution to journalArticle

  4. Acute Vascular Effects of Vascular Endothelial Growth Factor Inhibition in the Forearm Arterial Circulation

    Cameron, A. C., Welsh, P., Neves, K., Newby, D., Touyz, R. & Lang, N., 19 Aug 2019, In : Journal of Hypertension.

    Research output: Contribution to journalArticle

  5. Standardization of preclinical PET/CT imaging to improve quantitative accuracy, precision and reproducibility: a multi-center study

    McDougald, W., Vanhove, C., Lehnert, A., Lewellen, B., Wright, J., Mingarelli, M., Corral, C. A., Schneider, J. E., Plein, S., Newby, D., Welch, A., Miyaoka, R., Vandenberghe, S. & Tavares, A., 19 Aug 2019, In : Journal of Nuclear Medicine.

    Research output: Contribution to journalArticle

  6. Sex-Related Differences in the Extent of Myocardial Fibrosis in Patients with Aortic Valve Stenosis

    Tastet, L., Kwiecinski, J., Pibarot, P., Capoulade, R., Everett, R., Newby, D., Shen, M., Guzzetti, E., Arsenault, M., Bedard, E., Larose, E., Beaudoin, J., Dweck, M. & Clavel, M-A., 14 Aug 2019, In : JACC. Cardiovascular imaging.

    Research output: Contribution to journalArticle

  7. Ticagrelor to reduce myocardial injury in patients with high-risk coronary artery plaque

    Moss, A., Dweck, M., Doris, M., Andrews, J., Bing, R., O Forsythe, R., Cartlidge, T., Pawade, T., Daghem, M., Raftis, J., Williams, M., van Beek, E., Forsyth, L., Lewis, S., Lee, R., Shah, A., Mills, N., Newby, D. & Adamson, P., 14 Aug 2019, In : Journal of the American College of Cardiology.

    Research output: Contribution to journalArticle

  8. Non-invasive in vivo imaging of acute thrombosis: development of a novel factor XIIIa radiotracer

    Andrews, J., Portal, C., Walton, T., Macaskill, M., Hadoke, P., Corral, C. A., Lucatelli, C., Wilson, S., Macnaught, G., Dweck, M., Newby, D. & Tavares, A., 13 Aug 2019, In : European Heart Journal - Cardiovascular Imaging.

    Research output: Contribution to journalArticle

  9. Molecular coronary plaque imaging using 18F-fluoride

    Moss, A., Doris, M., Andrews, J., Bing, R., Daghem, M., van Beek, E., Forsyth, L., Shah, A., Williams, M., Sellers, S. L., Leipsic, J., Parker, R., Newby, D. & Adamson, P., 6 Aug 2019, In : Circulation: Cardiovascular Imaging.

    Research output: Contribution to journalArticle

  10. Triple-gated motion and blood pool clearance corrections improve reproducibility of coronary 18F-NaF PET

    Lyngby Lassen, M., Kwiecinski, J., Dey, D., Cadet, S., Germano, G., Berman, D. S., Adamson, P., Moss, A. J., Dweck, M., Newby, D. & Slomka, P. J., 5 Aug 2019, In : European Journal of Nuclear Medicine and Molecular Imaging.

    Research output: Contribution to journalArticle

  11. Global burden of atherosclerotic cardiovascular disease in people with hepatitis C virus infection: a systematic review, meta-analysis, and modelling study

    Lee, K. K., Stelzle, D., Bing, R., Anwar, M., Strachan, F., Bashir, S., Newby, D. E., Shah, J. S., Chung, M. H., Bloomfield, G. S., Longenecker, C. T., Bagchi, S., Kottilil, S., Blach, S., Razavi, H., Mills, P. R., Mills, N. L., Mcallister, D. A. & Shah, A. S. V., 31 Jul 2019, In : Lancet Gastroenterology and Hepatology.

    Research output: Contribution to journalArticle

  12. Standardized reporting systems for computed tomography coronary angiography and calcium scoring: A real-world validation of CAD-RADS and CAC-DRS in patients with stable chest pain

    Williams, M. C., Moss, A., Dweck, M., Hunter, A., Pawade, T., Adamson, P., Shah, A. S. V., Alam, S., Maroules, C. D., Van Beek, E. J., Cury, R., Nicol, E. D., Newby, D. E. & Roditi, G., 26 Jul 2019, In : Journal of Cardiovascular Computed Tomography.

    Research output: Contribution to journalArticle

  13. Convalescent troponin and cardiovascular death following acute coronary syndrome

    Adamson, P. D., Mcallister, D., Pilbrow, A., Pickering, J. W., Poppe, K., Shah, A., Whalley, G., Ellis, C., Mills, N. L., Newby, D. E., Pemberton, C., Troughton, R. W., Doughty, R. N. & Richards, A. M., 23 Jul 2019, In : Heart.

    Research output: Contribution to journalArticle

  14. Manganese-enhanced MRI of the myocardium

    Spath, N., Thompson, G., Baker, A., Dweck, M., Newby, D. & Semple, SI., 23 Jul 2019, In : Heart.

    Research output: Contribution to journalReview article

  15. Disentangled representation learning in cardiac image analysis

    Chartsias, A., Joyce, T., Papanastasiou, G., Semple, S., Williams, M., Newby, D. E., Dharmakumar, R. & Tsaftaris, S. A., 18 Jul 2019, In : Medical image analysis. 1 p., 101535.

    Research output: Contribution to journalArticle

  16. Frontiers in positron emission tomography imaging of the vulnerable atherosclerotic plaque

    Macaskill, M., Newby, D. & Tavares, A., 24 Jun 2019, In : Cardiovascular Research.

    Research output: Contribution to journalReview article

  17. Clinical determinants of plasma cardiac biomarkers in patients with stable chest pain

    Bing, R., Henderson, J., Hunter, A. L., Williams, M., Moss, A., Shah, A. S., McAllister, D., Dweck, M., Newby, D., Mills, N. & Adamson, P., 1 Jun 2019, In : Heart.

    Research output: Contribution to journalArticle

  18. Kinetic modelling and quantification bias in small animal PET studies with [18F]AB5186, a novel 18 kDa translocator protein radiotracer

    Macaskill, M. G., Walton, T., Williams, L., Morgan, T. E. F., Alcaide-corral, C. J., Dweck, M. R., Gray, G. A., Newby, D. E., Lucatelli, C., Sutherland, A., Pimlott, S. L., Tavares, A. A. S. & Garg, P. K. (ed.), 31 May 2019, In : PLoS ONE. 14, 5, p. e0217515

    Research output: Contribution to journalArticle

  19. Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis

    Zheng, K. H., Tsimikas, S., Pawade, T., Kroon, J., Jenkins, W. S. A., Doris, M. K., White, A. C., Timmers, N. K. L. M., Hjortnaes, J., Rogers, M. A., Aikawa, E., Arsenault, B. J., Witztum, J. L., Newby, D. E., Koschinsky, M. L., Fayad, Z. A., Stroes, E. S. G., Boekholdt, S. M. & Dweck, M. R., 7 May 2019, In : Journal of the American College of Cardiology. 73, 17, p. 2150-2162

    Research output: Contribution to journalArticle

  20. Coronary Atherosclerosis Imaging by CT to Improve Clinical Outcomes

    Williams, M., Newby, D. & Nicol, E., 29 Mar 2019, In : Journal of Cardiovascular Computed Tomography.

    Research output: Contribution to journalArticle

  21. Distance Oriented Particle Swarm Optimizer for Brain Image Registration

    Wang, C., goatman, K., Boardman, J., Beveridge, E., Newby, D. & Semple, S., 29 Mar 2019, In : IEEE Access. 7, p. 56016 - 56027

    Research output: Contribution to journalArticle

  22. Detection and Prediction of Bioprosthetic Aortic Valve Degeneration

    Cartlidge, T., Doris, M., Sellers, S. L., Pawade, T., White, A. C., Pessotto, R., Kwiecinski, J., Fletcher, A., Alcaide, C., Lucatelli, C., Densem, C., Rudd, J. H., van Beek, E., Tavares, A., Virmani, R., Berman, D., Leipsic, J. A. & Newby, D., 19 Mar 2019, In : Journal of the American College of Cardiology. 73, 10, p. 1107-1119

    Research output: Contribution to journalArticle

  23. Imaging Biomarkers for Abdominal Aortic Aneurysms: Finding the Breakthrough

    O Forsythe, R. & Newby, D., 15 Mar 2019, In : Circulation.

    Research output: Contribution to journalEditorial

  24. Rationale and design of the randomized, controlled early valve replacement guided by biomarkers of left ventricular decompensation in asymptomatic patients with severe aortic stenosis (EVOLVED) trial

    Bing, R., Everett, R., Tuck, C., Semple, S., Lewis, S., Harkess, R., Mills, N. L., Treibel, T. A., Prasad, S., Greenwood, J. P., Mccann, G. P., Newby, D. E. & Dweck, M. R., 15 Mar 2019, In : The American Heart Journal.

    Research output: Contribution to journalArticle

  25. Breast arterial calcification on mammography and risk of coronary artery disease: A SCOT-HEART sub-study

    McLenachan, S., Camilleri, F., Smith, M., Newby, D. & Williams, M., 22 Feb 2019, In : Clinical Radiology.

    Research output: Contribution to journalArticle

  26. Using radiation safely in cardiology - what imagers need to know

    Williams, M., Stewart, C., Weir, N. W. & Newby, D., 18 Feb 2019, In : Heart.

    Research output: Contribution to journalArticle

  27. Peri-coronary adipose tissue density is associated with 18F-sodium fluoride coronary uptake in stable patients with high-risk plaques.

    Kwiecinski, J., Dey, D., Cadet, S., Lee, S-E., Otaki, Y., Huynh, P. T., Doris, M., Eisenberg, E., Yun, M., Jansen, M., Williams, M., Tamarappoo, B. K., Friedman, J., Dweck, M., Newby, D., Chang, H-J. & Slomka, P. J., 13 Feb 2019, In : JACC. Cardiovascular imaging.

    Research output: Contribution to journalArticle

  28. MRI Relaxometry for Quantitative Analysis of USPIO Uptake in Cerebral Small Vessel Disease

    Thrippleton, M., Blair, G., Valdes-hernandez, M., Glatz, A., Semple, S., Doubal, F., Vesey, A., Marshall, I., Newby, D. & Wardlaw, J., 12 Feb 2019, In : International Journal of Molecular Sciences. 20, 3, p. 776

    Research output: Contribution to journalArticle

  29. Complications and Prognosis of Patients Undergoing Apical or Septal Right Ventricular Pacing

    Spath, N., Wang, K., Venkatasubramanian, S., Fersia, O., Newby, D., Lang, C., Grubb, N. & Dweck, M., 9 Feb 2019, In : Open heart.

    Research output: Contribution to journalArticle

  30. Disease Activity in Mitral Annular Calcification - a Multimodality Study

    Massera, D., Trivieri, M. G., Andrews, J., Sartori, S., Abgral, R., Chapman, A., Jenkins, W., Vesey, A., Doris, M., Pawade, T., Zheng, K. H., Kizer, J. R., Newby, D. & Dweck, M., 4 Feb 2019, In : Circulation: Cardiovascular Imaging.

    Research output: Contribution to journalArticle

  31. Imaging and impact of myocardial fibrosis in aortic stenosis

    Bing, R., Cavalcante, J. L., Everett, R., Clavel, M-A., Newby, D. & Dweck, M., 4 Feb 2019, In : JACC. Cardiovascular imaging.

    Research output: Contribution to journalArticle

  32. Coronary Artery Plaque Characteristics Associated With Adverse Outcomes in the SCOT-HEART Study

    Williams, M. C., Moss, A. J., Dweck, M., Adamson, P. D., Alam, S., Hunter, A., Shah, A. S. V., Pawade, T., Weir-mccall, J. R., Roditi, G., Van Beek, E. J. R., Newby, D. E. & Nicol, E. D., 29 Jan 2019, In : Journal of the American College of Cardiology. 73, 3, p. 291-301

    Research output: Contribution to journalArticle

  33. 18F-fluoride signal amplification identifies microcalcifications associated with atherosclerotic plaque instability in PET/CT images

    Creager, M., Hohl, T., Hutcheson, J., Moss, A., Schlotter, F., Blaser, M. C., Park, M-A., Lee, L. H., Singh, S. A., Corral, C. A., Tavares, A., Newby, D., Kijewski, M. F., Aikawa, M., Di Carli, M., Dweck, M. & Aikawa, E., 15 Jan 2019, In : Circulation: Cardiovascular Imaging.

    Research output: Contribution to journalArticle

  34. The SCOT-HEART Trial. What we observed and what we learned

    Adamson, P. D. & Newby, D. E., 4 Jan 2019, In : Journal of Cardiovascular Computed Tomography.

    Research output: Contribution to journalArticle

  35. Multimodal cardiac segmentation using disentangled representation learning

    Chartsias, A., Papanastasiou, G., Wang, C., Stirrat, C., Semple, S., Newby, D., Dharmakumar, R. & Tsaftaris, S., 2019.

    Research output: Contribution to conferencePaper

  36. 2018
  37. Imaging aortic wall inflammation

    Syed, M., Fletcher, A., Dweck, M., Forsythe, R. & Newby, D., 27 Dec 2018, In : Trends in cardiovascular medicine.

    Research output: Contribution to journalReview article

  38. Feasibility of Coronary 18F-Sodium Fluoride Positron-Emission Tomography Assessment With the Utilization of Previously Acquired Computed Tomography Angiography

    Kwiecinski, J., Adamson, P., Lassen, M. L., Doris, M., Moss, A., Cadet, S., Jansen, M., Dey, D., Lee, S-E., Yun, M., Chang, H-J., Dweck, M., Newby, D., Berman, D. & Slomka, P., 18 Dec 2018, In : Circulation: Cardiovascular Imaging.

    Research output: Contribution to journalArticle

  39. CONSERVE Your Energy and Resources

    Newby, D., 12 Dec 2018, In : Journal of the American College of Cardiology.

    Research output: Contribution to journalEditorial

  40. Analytical Quantification of Aortic Valve 18F-Sodium Fluoride PET Uptake

    Massera, D., Doris, M., Cadet, S., Kwiecinski, J., Pawade, T., Peeters, F. E. C. M., Dey, D., Newby, D., Dweck, M. & Slomka, P., 29 Nov 2018, In : Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

    Research output: Contribution to journalArticle

  41. Targeting Non-coding RNA in Vascular Biology and Disease

    Hung, J., Miscianinov, V., Sluimer, J. C., Newby, D. E. & Baker, A. H., 22 Nov 2018, In : Frontiers in physiology. 9

    Research output: Contribution to journalArticle

  42. Data-driven gross patient motion detection and compensation: Implications for coronary 18F-NaF PET imaging

    Lyngby Lassen, M., Kwiecinski, J., Cadet, S., Dey, D., Wang, C., Dweck, M., Newby, D., Berman, D. & Slomka, P. J., 15 Nov 2018, In : Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

    Research output: Contribution to journalArticle

  43. Novel high-sensitivity cardiac troponin I assay in patients with suspected acute coronary syndrome

    Chapman, A., Fujisawa, T., Lee, K. K., Andrews, J., Anand, A., Sandeman, D., Ferry, A. V., Stewart, S., Marshall, L., Strachan, F., Gray, A., Newby, D., Shah, A. & Mills, N., 15 Nov 2018, In : Heart.

    Research output: Contribution to journalArticle

  44. Myocardial and Systemic Inflammation in Acute Stress-Induced (Takotsubo) Cardiomyopathy

    Scally, C., Abbas, H., Ahearn, T., Srinivasan, J., Mezincescu, A., Rudd, A., Spath, N., Yucel-Finn, A., Yuecel, R., Oldroyd, K., Dospinescu, C., Horgan, G., Broadhurst, P., Henning, A., Newby, D. E., Semple, S., Wilson, H. & Dawson, D. K., 11 Nov 2018, In : Circulation.

    Research output: Contribution to journalArticle

  45. Non-invasive imaging of the coronary arteries

    Adamson, P. & Newby, D., 2 Nov 2018, In : European Heart Journal.

    Research output: Contribution to journalReview article

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