Edinburgh Research Explorer

Dinesh Soares, PhD

(Former employee or visitor)

  1. 2004
  2. Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded

    Blein, S., Ginham, R., Uhrin, D., Smith, B. O., Soares, D. C., Veltel, S., McIlhinney, R. A. J., White, J. H. & Barlow, P. N., 2004, In: Journal of Biological Chemistry. 279, 46, p. 48292-306 15 p.

    Research output: Contribution to journalArticlepeer-review

  3. 2005
  4. ARABIDOPSIS CRINKLY4 function, internalization, and turnover are dependent on the extracellular crinkly repeat domain

    Gifford, M. L., Robertson, F. C., Soares, D. C. & Ingram, G. C., 2005, In: The Plant Cell. 17, 4, p. 1154-66 13 p.

    Research output: Contribution to journalArticlepeer-review

  5. Large-scale modelling as a route to multiple surface comparisons of the CCP module family

    Soares, D. C., Gerloff, D. L., Syme, N. R., Coulson, A. F. W., Parkinson, J. & Barlow, P. N., 2005, In: Protein engineering, design & selection : PEDS. 18, 8, p. 379-88 10 p.

    Research output: Contribution to journalArticlepeer-review

  6. Opportunities for new therapies based on the natural regulators of complement activation

    Brook, E., Herbert, A. P., Jenkins, H. T., Soares, D. C. & Barlow, P. N., 2005, In: Annals of the New York Academy of Sciences. 1056, p. 176-188 13 p.

    Research output: Contribution to journalArticlepeer-review

  7. Functional insights from the structure of the multifunctional C345C domain of C5 of complement

    Bramham, J., Thai, C-T., Soares, D. C., Uhrín, D., Ogata, R. T. & Barlow, P., 18 Mar 2005, In: Journal of Biological Chemistry. 280, 11, p. 10636-10645 10 p.

    Research output: Contribution to journalArticlepeer-review

  8. Structural Biology of the Complement System: Complement Control Protein Modules in the Regulators of Complement Activation

    Soares, D. & Barlow, P., 29 Mar 2005, CRC Press. Morikis, D. & Lambris, J. (eds.). Boca Raton, FL: CRC Press, p. 19-62 44 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  9. 2006
  10. Disease-associated sequence variations in factor H: A structural biology approach

    Herbert, A. P., Soares, D. C., Pangburn, M. K. & Barlow, P. N., 2006, Current Topics in Complement. Springer-Verlag GmbH, Vol. 586. p. 313-327 15 p. (Advances in Experimental Medicine and Biology ).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  11. 2007
  12. Molecular evolution of the human SRPX2 gene that causes brain disorders of the Rolandic and Sylvian speech areas

    Royer, B., Soares, D. C., Barlow, P. N., Bontrop, R. E., Roll, P., Robaglia-Schlupp, A., Blancher, A., Levasseur, A., Cau, P., Pontarotti, P. & Szepetowski, P., 2007, In: BMC Genetics. 8, 72, p. 1-9 9 p.

    Research output: Contribution to journalArticlepeer-review

  13. Structure-based mapping of DAF active site residues that accelerate the decay of C3 convertases

    Kuttner-Kondo, L., Hourcade, D. E., Anderson, V. E., Muqim, N., Mitchell, L., Soares, D. C., Barlow, P. N. & Medof, M. E., 2007, In: Journal of Biological Chemistry. 282, 25, p. 18552-62 11 p.

    Research output: Contribution to journalArticlepeer-review

  14. 2008
  15. The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae

    Obbard, D. J., Callister, D. M., Jiggins, F. M., Soares, D. C., Yan, G. & Little, T. J., 2008, In: BMC Evolutionary Biology. 8, 274, p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

  16. The DISC locus in psychiatric illness

    Chubb, J. E., Bradshaw, N. J., Soares, D. C., Porteous, D. J. & Millar, J. K., Jan 2008, In: Molecular Psychiatry. 13, 1, p. 36-64 29 p.

    Research output: Contribution to journalArticlepeer-review

  17. Structure of the N-terminal Region of Complement Factor H and Conformational Implications of Disease-linked Sequence Variations

    Hocking, H. G., Herbert, A. P., Kavanagh, D., Soares, D. C., Ferreira, V. P., Pangburn, M. K., Uhrín, D. & Barlow, P. N., 4 Apr 2008, In: Journal of Biological Chemistry. 283, 14, p. 9475-9487 13 p.

    Research output: Contribution to journalArticlepeer-review

  18. A common variant in the 3'UTR of the GRIK4 glutamate receptor gene affects transcript abundance and protects against bipolar disorder

    Pickard, B. S., Knight, H. M., Hamilton, R. S., Soares, D. C., Walker, R., Boyd, J. K. F., Machell, J., Maclean, A., McGhee, K. A., Condie, A., Porteous, D. J., Clair, D. S., Davis, I., Blackwood, D. H. R. & Muir, W. J., 30 Sep 2008, In: Proceedings of the National Academy of Sciences (PNAS). 105, 39, p. 14940-14945 6 p.

    Research output: Contribution to journalArticlepeer-review

  19. 2009
  20. NDE1 and NDEL1: Multimerisation, alternate splicing and DISC1 interaction

    Bradshaw, N. J., Christie, S., Soares, D. C., Carlyle, B. C., Porteous, D. J. & Millar, J. K., Jan 2009, In: Neuroscience Letters. 449, 3, p. 228-233 6 p.

    Research output: Contribution to journalArticlepeer-review

  21. An interrupted beta-propeller and protein disorder: structural bioinformatics insights into the N-terminus of alsin

    Soares, D. C., Barlow, P. N., Porteous, D. J. & Devon, R. S., Feb 2009, In: Journal of Molecular Modeling. 15, 2, p. 113-122 10 p.

    Research output: Contribution to journalArticlepeer-review

  22. Solution structure of factor I-like modules from complement C7 reveals a pair of follistatin domains in compact pseudosymmetric arrangement

    Phelan, M. M., Thai, C-T., Soares, D. C., Ogata, R. T., Barlow, P. N. & Bramham, J., Jul 2009, In: Journal of Biological Chemistry. 284, 29, p. 19637-19649 13 p.

    Research output: Contribution to journalArticlepeer-review

  23. A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression

    Knight, H. M., Pickard, B. S., Maclean, A., Malloy, M. P., Soares, D. C., McRae, A. F., Condie, A., White, A., Hawkins, W., McGhee, K., van Beck, M., MacIntyre, D. J., Starr, J., Deary, I. J., Visscher, P. M., Porteous, D. J., Cannon, R. E., St Clair, D., Muir, W. J. & Blackwood, D. H., Dec 2009, In: American Journal of Human Genetics. 85, 6, p. 833-846 14 p.

    Research output: Contribution to journalArticlepeer-review

  24. eEF1A2 and neuronal degeneration

    Abbott, C. M., Newbery, H. J., Squires, C. E., Brownstein, D., Griffiths, L. A. & Soares, D. C., Dec 2009, In: Biochemical Society Transactions. 37, Pt 6, p. 1293-7 5 p.

    Research output: Contribution to journalArticlepeer-review

  25. 2010
  26. The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module

    Schmidt, C. Q., Herbert, A. P., Mertens, H. D. T., Guariento, M., Soares, D. C., Uhrin, D., Rowe, A. J., Svergun, D. I. & Barlow, P. N., 2010, In: Journal of Molecular Biology. 395, 1, p. 105-22 18 p.

    Research output: Contribution to journalArticlepeer-review

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