Edinburgh Research Explorer

Prof Donal O'Carroll

Chair of Stem Cell Biology

  1. 2019
  2. Targeting the RNA m6A reader YTHDF2 selectively compromises cancer stem cells in acute myeloid leukemia

    Paris, J., Morgan, M., Monteiro De Campos, J., Spencer, G., Shmakova, A., Ivanova, I., Mapperley, C., Lawson, H., Wotherspoon, D., Pires Sepulveda, C., Vukovic, M., Allen, L., Sarapuu, A., Tavosanis, A., Guitart, A., Villacreces, A., Much, C., Junho, C., Anvari Azar, A., Van De Lagemaat, L. & 7 others, Vernimmen, D., Nehme, A., Mazurier, F., Somervaille, T., Gregory, R., O'Carroll, D. & Kranc, K., 3 Jul 2019, In : Cell Stem Cell. 25, 12 p.

    Research output: Contribution to journalArticle

  3. A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis

    Morgan, M., Kabayama, Y., Much, C., Ivanova, I., Di Giacomo, M., Auchynnikava, T., Monahan, J. M., Vitsios, D. M., Vasiliauskaitė, L., Comazzetto, S., Rappsilber, J., Allshire, R. C., Porse, B. T., Enright, A. J. & O'Carroll, D., 7 Jan 2019, In : Cell Research . 12 p.

    Research output: Contribution to journalArticle

  4. 2018
  5. PIWI-interacting RNAs: small RNAs with big functions

    Ozata, D. M., Gainetdinov, I., Zoch, A., O’Carroll, D. & Zamore, P. D., 16 Nov 2018, In : Nature Reviews Genetics. 20 p.

    Research output: Contribution to journalReview article

  6. Deficiency in the nuclear long noncoding RNA causes myogenic defects and heart remodeling in mice

    Ballarino, M., Cipriano, A., Tita, R., Santini, T., Desideri, F., Morlando, M., Colantoni, A., Carrieri, C., Nicoletti, C., Musarò, A., Carroll, D. O. & Bozzoni, I., 14 Sep 2018, In : EMBO Journal. 37, 18

    Research output: Contribution to journalArticle

  7. Terminal uridylyltransferases target RNA viruses as part of the innate immune system

    Le Pen, J., Jiang, H., Di Domenico, T., Kneuss, E., Kosałka, J., Leung, C., Morgan, M., Much, C., Rudolph, K. L. M., Enright, A. J., O'Carroll, D., Wang, D. & Miska, E. A., 13 Aug 2018, In : Nature Structural & Molecular Biology. 25, 9, p. 778-786 9 p.

    Research output: Contribution to journalArticle

  8. Defective germline reprogramming rewires the spermatogonial transcriptome

    Vasiliauskaitė, L., Berrens, R. V., Ivanova, I., Carrieri, C., Reik, W., Enright, A. J. & O’carroll, D., 30 Apr 2018, In : Nature Structural & Molecular Biology. 25, 5, p. 394-404 16 p.

    Research output: Contribution to journalArticle

  9. MicroRNA degradation by a conserved target RNA regulates animal behavior

    Bitetti, A., Mallory, A. C., Golini, E., Carrieri, C., Carreño Gutiérrez, H., Perlas, E., Pérez-Rico, Y. A., Tocchini-Valentini, G. P., Enright, A. J., Norton, W. H. J., Mandillo, S., O'Carroll, D. & Shkumatava, A., 26 Feb 2018, In : Nature Structural & Molecular Biology. 25, 3, p. 244-251 8 p.

    Research output: Contribution to journalArticle

  10. 2017
  11. Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells

    Wasserman, G. A., Szymaniak, A. D., Hinds, A. C., Yamamoto, K., Kamata, H., Smith, N. M. S., Hillard, K., Carrieri, C., Labadorf, A. T., Quinton, L. J., Ai, X., Varelas, X., Chen, F., Mizgerd, J. P., Fine, A., O'Carroll, D. & Jones, M. R., 2 Oct 2017, In : Journal of Clinical Investigation. 127, 10, p. 3866-3876 11 p.

    Research output: Contribution to journalArticle

  12. The RNA m6A reader YTHDF2 is essential for the post-transcriptional regulation of the maternal transcriptome and oocyte competence.

    Ivanova, I., Much, C., Di Giacomo, M., Azzi, C., Morgan, M., Morgan, M., Ventura De Oliveira Moreira, P., Monahan, J., Carrieri, C., Enright, A. J. & O'Carroll, D., 30 Aug 2017, In : Molecular Cell.

    Research output: Contribution to journalArticle

  13. mRNA 3ʹ uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome

    Morgan, M., Much, C., DiGiacomo, M., Azzi, C., Ivanova, I., Vitsios, D., Pistolic, J., Collier, P., Ventura De Oliveira Moreira, P., Benes, V., Enright, A. J. & O'Carroll, D., 9 Aug 2017, In : Nature.

    Research output: Contribution to journalArticle

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