Edinburgh Research Explorer

Duncan Sproul

Research Fellow

  1. 2020
  2. Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation

    Patani, H., Rushton, M. D., Higham, J., Teijeiro, S. A., Oxley, D., Cutillas, P., Sproul, D. & Ficz, G., 22 Jul 2020, In : Nature Communications.

    Research output: Contribution to journalArticle

  3. Activation of transcription factor circuity in 2i-induced ground state pluripotency is independent of repressive global epigenetic landscapes

    Shukla, R., Mjoseng, H. K., Thomson, J., Kling, S., Sproul, D., Dunican, D., Ramsahoye, B., Wongtawan, T., Treindl, F., Templin, M. F., Adams, I., Pennings, S. & Meehan, R., 25 Jun 2020, In : Nucleic Acids Research.

    Research output: Contribution to journalArticle

  4. 2019
  5. An epigenetic predictor of death captures multi-modal measures of brain health

    Hillary, R., Stevenson, A., Cox, S., McCartney, D. L., Harris, S., Seeboth, A., Higham, J., Sproul, D., Taylor, A., Redmond, P., Corley, J., Pattie, A., Valdes Hernandez, M., Muñoz Maniega, S., Bastin, M., Wardlaw, J., Horvath, S., Ritchie, C., Spires-Jones, T., McIntosh, A. & 3 others, Evans, K. L., Deary, I. & Marioni, R. E., 3 Dec 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  6. Age-related clonal haematopoiesis is associated with increased epigenetic age

    Robertson, N., Hillary, R., McCartney, D. L., Terradas Terradas, M., Higham, J., Sproul, D., Deary, I., Kirschner, K., Marioni, R. & Chandra, T., 19 Aug 2019, In : Current Biology. 29, 16, p. R786-R787

    Research output: Contribution to journalArticle

  7. Gain of function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of polycomb-regulated regions

    Heyn, P., Logan, C., Fluteau, A., Challis, R., Auchynnikava, T., Martin, C-A., Marsh, J. A., Taglini, F., Kilanowski, F., Parry, D., Cormier-Daire, V., Fong, C-T., Gibson, K., Hwa, V., Ibanez, L., Robertson, S. P., Sebastiani, G., Rappsilber, J., Allshire, R., Reijns, M. A. M. & 3 others, Dauber, A., Sproul, D. & Jackson, A. P., 5 Jan 2019, In : Nature Genetics.

    Research output: Contribution to journalArticle

  8. 2018
  9. Genotype effects contribute to variation in longitudinal methylome patterns in older people

    Zhang, Q., Marioni, R., Robinson, M. R., Higham, J., Sproul, D., Wray, N. R., Deary, I., Mcrae, A. F. & Visscher, P. M., 22 Oct 2018, In : Genome Medicine. 10, 75, p. 1-11

    Research output: Contribution to journalArticle

  10. 2017
  11. Variable outcome and methylation status according to CEBPA mutant type in double-mutated acute myeloid leukemia patients and the possible implications for treatment

    El-Sharkawi, D., Sproul, D., Allen, C. G., Feber, A., Wright, M., Hills, R. K., Linch, D. C. & Gale, R. E., 12 Oct 2017, In : Haematologica.

    Research output: Contribution to journalArticle

  12. Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators

    Bulstrode, H., Johnstone, E., Marques-Torrejon, M. A., Ferguson, K. M., Bressan, R. B., Blin, C., Grant, V., Gogolok, S., Gangoso, E., Gagrica, S., Ender, C., Fotaki, V., Sproul, D., Bertone, P. & Pollard, S. M., 15 Apr 2017, In : Genes and Development. 31, 8, p. 757-773 7 p.

    Research output: Contribution to journalArticle

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