Personal Chair of NMR Spectroscopy
Willingness to take PhD students: Yes
Analysis of complex mixtures
We are developing multidimensional NMR methods and mass spectrometry approaches, in combination with chemical modification schemes, to investigate the most complex mixtures on earth - humic substances - heterogeneous mixtures containing thousands of organic molecules produced by the degradation of plant and animal residues. We also study other, more pleasant mixtures, like Scotch whisky.
Carbohydrate structures and protein-carbohydrate interactions
Glycosaminoglycans isolated from marine environment are complex, heterogeneous polysaccharides that represent a considerable challenge for the NMR structure determination. We investigate interactions between glycosaminoglycans and selectins – proteins involved in inflammation and metastasis progression. We also study the conformation of carbohydrates using scalar and residual dipolar coupling constants.
NMR methodology
Using our 400-800 MHz NMR spectrometers equipped with cryoprobes we are developing NMR methodologies for efficient acquisition of NMR spectra applicable across the field of chemistry and biochemistry. This includes fast NMR methods for kinetic and mechanistic studies.
Development of NMR methodology and its application to studies of complex mixtures, chemical reactions, carbohydrate structures and protein-carbohydrate interactions.
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Activity: Participating in or organising an event types › Public Engagement – Schools engagement
Activity: Publication peer-review and editorial work types › Publication peer-review
Activity: Participating in or organising an event types › Participation in conference
ID: 15808