Edinburgh Research Explorer

Emily Sena

Research Fellow

  1. 2007
  2. Comparison of treatment effects between animal experiments and clinical trials: systematic review

    Perel, P., Roberts, I., Sena, E., Wheble, P., Briscoe, C., Sandercock, P., Macleod, M., Mignini, L. E., Jayaram, P. & Khan, K. S., 27 Jan 2007, In: British Medical Journal (BMJ). 334, 7586, p. 197-197

    Research output: Contribution to journalArticlepeer-review

  3. Systematic review and meta-analysis of the efficacy of tirilazad in experimental stroke

    Sena, E., Wheble, P., Sandercock, P. & Macleod, M., Feb 2007, In: Stroke. 38, 2, p. 388-394 7 p.

    Research output: Contribution to journalReview articlepeer-review

  4. How can we improve the pre-clinical development of drugs for stroke?

    Sena, E., van der Worp, H. B., Howells, D. & Macleod, M., Sep 2007, In: Trends in Neurosciences. 30, 9, p. 433-439 7 p.

    Research output: Contribution to journalArticlepeer-review

  5. Hypothermia in animal models of acute ischaemic stroke: A systematic review and meta-analysis

    Van Der Worp, H. B., Sena, E. S., Donnan, G. A., Howells, D. W. & Macleod, M. R., Dec 2007, In: Brain. 130, 12, p. 3063-3074 12 p.

    Research output: Contribution to journalReview articlepeer-review

  6. 2008
  7. A systematic review and meta-analysis of the efficacy of piracetam and piracetam-like compounds in experimental stroke

    Wheble, P. C. R., Sena, E. S. & Macleod, M. R., 2008, In: Cerebrovascular diseases. 25, 1-2, p. 5-11 7 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  8. Empirical evidence of bias in the design of experimental stroke studies - A metaepidemiologic approach

    Crossley, N. A., Sena, E., Goehler, J., Horn, J., van der Worp, B., Bath, P. M. W., Macleod, M. & Dirnagl, U., Mar 2008, In: Stroke. 39, 3, p. 929-934 6 p.

    Research output: Contribution to journalArticlepeer-review

  9. Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality

    Macleod, M. R., van der Worp, H. B., Sena, E. S., Howells, D. W., Dirnagl, U. & Donnan, G. A., Oct 2008, In: Stroke. 39, 10, p. 2824-2829 6 p.

    Research output: Contribution to journalArticlepeer-review

  10. 2009
  11. Systematic Review and Stratified Meta-analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke

    Banwell, V., Sena, E. S. & Macleod, M. R., 2009, In: Journal of Stroke and Cerebrovascular Diseases. 18, 4, p. 269-276 8 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  12. Reprint: Good laboratory practice: preventing introduction of bias at the bench

    Macleod, M. R., Fisher, M., O'Collins, V., Sena, E. S., Dirnagl, U., Bath, P. M. W., Buchan, A., van der Worp, H. B., Traystman, R. J., Minematsu, K., Donnan, G. A. & Howells, D. W., Feb 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 2, p. 221-223 3 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  13. REPRINT: Good laboratory practice: Preventing introduction of bias at the bench

    Macleod, M. R., Fisher, M., O'collins, V., Sena, E. S., Dirnagl, U., Bath, P. M. W., Buchan, A., Van Der Worp, H. B., Traystman, R. J., Minematsu, K., Donnan, G. A. & Howells, D. W., 25 Feb 2009, In: International Journal of Stroke. 4, 1, p. 3-5 3 p.

    Research output: Contribution to journalArticlepeer-review

  14. Good Laboratory Practice Preventing Introduction of Bias at the Bench

    Macleod, M. R., Fisher, M., O'Collins, V., Sena, E. S., Dirnagl, U., Bath, P. M. W., Buchan, A., van der Worp, H. B., Traystman, R., Minematsu, K., Donnan, G. A. & Howells, D. W., Mar 2009, In: Stroke. 40, 3, p. E50-E52 3 p.

    Research output: Contribution to journalArticlepeer-review

  15. A Systematic Review Of Erythropoietin In Experimental Stroke

    Forsberg, K. O., Jerndal, M. J., Sena, E. S., O'Collins, V. E., Macleod, M. R., Linden, T., Nilsson, M. & Howells, D. W., Apr 2009, In: Stroke. 40, 4, p. E215-E215 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  16. 2010
  17. An Enriched Environment Improves Sensorimotor Function Post-Ischemic Stroke

    Janssen, H., Bernhardt, J., Collier, J. M., Sena, E. S., McElduff, P., Attia, J., Pollack, M., Howells, D. W., Nilsson, M., Calford, M. B. & Spratt, N. J., 2010, In: Neurorehabilitation and Neural Repair. 24, 9, p. 802-813 12 p.

    Research output: Contribution to journalArticlepeer-review

  18. Can Animal Models of Disease Reliably Inform Human Studies?

    van der Worp, H. B., Howells, D. W., Sena, E. S., Porritt, M. J., Rewell, S., O'Collins, V. & Macleod, M. R., Mar 2010, In: PLoS Medicine. 7, 3, p. - 8 p., e1000245.

    Research output: Contribution to journalArticlepeer-review

  19. Publication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy

    Sena, E. S., van der Worp, H. B., Bath, P. M. W., Howells, D. W. & Macleod, M. R., Mar 2010, In: PLoS Biology. 8, 3, 8 p., e1000344.

    Research output: Contribution to journalArticlepeer-review

  20. A systematic review and meta-analysis of erythropoietin in experimental stroke

    Jerndal, M., Forsberg, K., Sena, E. S., Macleod, M. R., O'Collins, V. E., Linden, T., Nilsson, M. & Howells, D. W., May 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 5, p. 961-968 8 p.

    Research output: Contribution to journalArticlepeer-review

  21. Different strokes for different folks: the rich diversity of animal models of focal cerebral ischemia

    Howells, D. W., Porritt, M. J., Rewell, S. S. J., O'Collins, V., Sena, E. S., van der Worp, H. B., Traystman, R. J. & Macleod, M. R., Aug 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 8, p. 1412-1431 20 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  22. Improving the translational hit of experimental treatments in multiple sclerosis

    Vesterinen, H. M., Sena, E. S., Ffrench-Constant, C., Williams, A., Chandran, S. & Macleod, M. R., Sep 2010, In: Multiple Sclerosis Journal. 16, 9, p. 1044-1055 12 p.

    Research output: Contribution to journalArticlepeer-review

  23. Factors affecting the apparent efficacy and safety of tissue plasminogen activator in thrombotic occlusion models of stroke: systematic review and meta-analysis

    Sena, E. S., Briscoe, C. L., Howells, D. W., Donnan, G. A., Sandercock, P. A. G. & Macleod, M. R., Dec 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 12, p. 1905-13 9 p.

    Research output: Contribution to journalArticlepeer-review

  24. 2011
  25. Making the most of animal data – improving the prospect of success in pragmatic trials in the neurosciences

    Egan, K. J., Sena, E. S., Vesterinen, H. M. & Macleod, M. R., 1 Jan 2011, In: Trials. 12, Suppl 1, p. A102

    Research output: Contribution to journalArticlepeer-review

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