Edinburgh Research Explorer

James Loan

ECAT Clinical Lecturer in Neurosurgery

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Education/Academic qualification

2017Master of Science (with Distinction), University of Edinburgh
2014Bachelor of Medicine and Bachelor of Surgery, University of Edinburgh
2011Bachelor of Science (First Class Honours), University of Edinburgh

Professional Qualifications

2015Member of the Royal College of Surgeons of Edinburgh, MRCS (Ed)

Current Research Interests

Research summary

I am a doctor training in neurosurgery. Broadly, I am interested in understanding why inflammatory responses to acute brain injury vary between people and how these impact on long-term clinical outcome. This is important to inform patient selection for surgery and may allow targeted therapeutic development. 

Current interests

Towards my PhD, I am developing in vitro and in vivo models of brain haemorrhage to investigate how microglia, the resident immune cells of the brain, modulate astrocyte and neuronal responses to haemorrhage. By accessing brain tissue and clinical data kindly donated by patients who have died following haemorrhage we will identify which disease modifying factors are translatable to human disease. My PhD is supervised by Prof. Giles Hardingham, Dr. Barry McColl and Prof. Rustam Salman and is funded by the Wellcome Trust.

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Research Groups

ID: 41094052