Edinburgh Research Explorer

Joanna Wardlaw

Personal Chair Applied Neuroimaging

  1. 2021
  2. Low- versus Standard-dose Alteplase in Acute Lacunar Ischemic Stroke: The ENCHANTED Trial

    Zhou, Z., Delcourt, C., Xia, C., Yoshimura, S., Carcel, C., Torii-Yoshimura, T., You, S., Malavera, A., Chen, X., Hackett, M. L., Woodward, M., Chalmers, J., Xu, J., Robinson, T. G., Parsons, M. W., Demchuk, A. M., Lindley, R. I., Mair, G., Wardlaw, J. M. & Anderson, C. S., 3 Feb 2021, In: Neurology.

    Research output: Contribution to journalArticlepeer-review

  3. Neuropsychiatric symptoms associated with cerebral small vessel disease: a systematic review and meta-analysis

    Clancy, U., Jochems, A., Doubal, F., Wardlaw, J., Gilmartin, D. & Knox, L., 1 Feb 2021, In: The Lancet Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  4. A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease

    Stringer, M. S., Lee, H., Huuskonen, M. T., MacIntosh, B. J., Brown, R., Montagne, A., Atwi, S., Ramirez, J., Jansen, M. A., Marshall, I., Black, S. E., Zlokovic, B. V., Benveniste, H. & Wardlaw, J. M., Feb 2021, In: Translational Stroke Research. 12, 1, p. 15-30 16 p.

    Research output: Contribution to journalReview articlepeer-review

  5. Real-world Independent Testing of e-ASPECTS Software (RITeS): statistical analysis plan

    Mair, G., Chappell, F., Martin, C., Dye, D., Bath, P. M., Muir, K. W., Von Kummer, R., Al-shahi Salman, R., Sandercock, P. A. G., Macleod, M., Sprigg, N., White, P. & Wardlaw, J. M., 27 Jan 2021, In: AMRC Open Research. 2, p. 20

    Research output: Contribution to journalArticlepeer-review

  6. A four-dimensional computational model of dynamic contrast-enhanced magnetic resonance imaging measurement of subtle blood-brain barrier leakage

    Bernal, J., Valdés-hernández, M. D. C., Escudero, J., Heye, A. K., Sakka, E., Armitage, P. A., Makin, S., Touyz, R. M., Wardlaw, J. M. & Thrippleton, M. J., 23 Jan 2021, In: NeuroImage. 230, p. 117786

    Research output: Contribution to journalArticlepeer-review

  7. Multi-national survey of current practice from imaging to treatment of atherosclerotic carotid stenosis

    Saba, L., Mossa-Basha, M., Abbott, A., Lanzino, G., Wardlaw, J., Hatsukami, T. S., Micheletti, G., Balestrieri, A., Hedin, U., Moody, A. R., Wintermark, M. & DeMarco, J. K., 13 Jan 2021, In: Cerebrovascular diseases.

    Research output: Contribution to journalArticlepeer-review

  8. Three major dimensions of human brain cortical ageing in relation to cognitive decline across the eighth decade of life

    Cox, S., Harris, M., Ritchie, S. J., Buchanan, C., Valdes Hernandez, M., Corley, J., Taylor, A., Madole, J. W., Harris, S., Whalley, H., McIntosh, A. M., Russ, T. C., Bastin, M. E., Wardlaw, J., Deary, I. & Tucker-Drob, E. M., 4 Jan 2021, In: Molecular Psychiatry. 12 p.

    Research output: Contribution to journalArticlepeer-review

  9. 2020
  10. Association of common genetic variants with brain microbleeds: A genome-wide association study

    Alzheimer's Disease Neuroimaging Initiative, 15 Dec 2020, In: Neurology. 95, 24, p. e3331-e3343

    Research output: Contribution to journalArticlepeer-review

  11. Brain network reorganisation and spatial lesion distribution in systemic lupus erythematosus

    Valdes Hernandez, M., Smith, K., Bastin, M. E., Amft, E. N., Ralston, S. H., Wardlaw, J. & Wiseman, S., 13 Dec 2020, In: Lupus.

    Research output: Contribution to journalArticlepeer-review

  12. Cerebral small vessel disease genomics and its implications across the lifespan

    Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., Hagenaars, S., Rajan, K. B., van den Akker, E., McWhirter, R. E., Trompet, S., Mishra, A. & 97 others, Saba, Y., Satizabal, C. L., Beaudet, G., Petit, L., Tsuchida, A., Zago, L., Schilling, S., Sigurdsson, S., Gottesman, R. F., Lewis, C. E., Aggarwal, N. T., Lopez, O. L., Smith, J. A., Valdes Hernandez, M., van der Grond, J., Wright, M. J., Knol, M. J., Dörr, M., Thomson, R., Bordes, C., Le Grand, Q., Duperron, M-G., Smith, A. V., Knopman, D. S., Schreiner, P. J., Evans, D. A., Rotter, J. I., Beiser, A. S., Muñoz Maniega, S., Beekman, M., Trollor, J. N., Stott, D. J., Vernooij, M. W., Wittfield, K., Niessen, W. J., Soumaré, A., Boerwinkle, E., Sidney, S. S., Turner, S. T., Davies, G., Thalamuthu, A., Völker, U., Van Buchem, M. A., Bryan, R. N., Dupuis, J., Bastin, M., Ames, D., Teumer, A., Amouyel, P., Kwok, J. B. J., Bülow, R., Deary, I., Schofield, P. R., Brodaty, H., Jiang, J., Tabara, Y., Setoh, K., Miyamoto, S., Yoshida, K., Nagata, M., Kamatani, Y., Matsuda, F., Psaty, B. M., Bennett, D. A., De Jager, P. L., Mosley, T. H., Sachdev, P. S., Schmidt, R., Warren, H. R., Evangelou, E., Trégouët, D. A., Ikram, M. A., Wen, W., DeCarli, C., Srikanth, V. K., Wouter Jukema, J., Slagboom, P. E., Kardia, S. L. R., Okada, Y., Mazoyer, B., Wardlaw, J., Nyquist, P. A., Mather, K. A., Grabe, H. J., Schmidt, H., van Duijn, C., Gudnason, V., Longstreth, W. T., Lenore, L. J., Lathrop, G. M., Campbell, A., Seshadri, S., Tzourio, C., Adams, H. H. H., Matthews, P. M., Fornage, M. & Debette, S., 8 Dec 2020, In: Nature Communications.

    Research output: Contribution to journalArticlepeer-review

  13. Hyperdense artery sign, symptomatic infarct swelling and effect of alteplase in acute ischaemic stroke

    Wu, S., Mair, G., Cohen, G., Morris, Z., Von Heijne, A., Bradey, N., Cala, L., Peeters, A., Farrall, A. J., Adami, A., Potter, G., Liu, M., Lindley, R. I., Sandercock, P. A. G. & Wardlaw, J. M., 27 Nov 2020, In: Stroke and Vascular Neurology. p. svn-2020-000569

    Research output: Contribution to journalArticlepeer-review

  14. Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: A community-based inception cohort study

    Loan, J. J., Gane, A. B., Moullaali, T. J., Rodrigues, M. A., Wardlaw, J., Salman, R. A., Samarasekera, N. & Lothian Audit of the Treatment of Cerebral Haemorrhage (LATCH) collaborators, 25 Nov 2020, In: International Journal of Stroke. p. 174749302097428

    Research output: Contribution to journalArticlepeer-review

  15. Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder

    Green, C., Shen, X., Stevenson, A. J., Conole, E. L. S., Harris, M. A., Barbu, M. C., Hawkins, E. L., Adams, M. J., Hillary, R. F., Lawrie, S. M., Evans, K. L., Walker, R. M., Morris, S. W., Porteous, D. J., Wardlaw, J. M., Douglas Steele, J., Waiter, G. D., Sandu, A., Campbell, A., Marioni, R. E. & 4 others, Cox, S. R., Cavanagh, J., Mcintosh, A. M. & Whalley, H. C., 19 Nov 2020, In: Brain, Behavior, and Immunity.

    Research output: Contribution to journalArticlepeer-review

  16. Cognitive impairment in sporadic cerebral small vessel disease: A systematic review and meta-analysis

    Hamilton, O., Backhouse, E., Janssen, E., Jochems, A., Maher, C., Ritakari, T., Stevenson, A., Xia, L., Deary, I. & Wardlaw, J., 13 Nov 2020, In: Alzheimer's & Dementia.

    Research output: Contribution to journalArticlepeer-review

  17. Relationship between nitrate headache and outcome in patients with acute stroke: results from the efficacy of nitric oxide in stroke (ENOS) trial

    Beishon, L., Woodhouse, L. J., Bereczki, D., Christensen, H. K., Collins, R., Gommans, J., Kruuse, C., Ntaios, G., Ozturk, S., Phillips, S., Pocock, S., Szatmari, S., Wardlaw, J., Sprigg, N. & Bath, P. M., 5 Nov 2020, In: Stroke and Vascular Neurology. p. svn-2020-000498

    Research output: Contribution to journalArticlepeer-review

  18. Association between Computed Tomographic Biomarkers of Cerebral Small Vessel Diseases and Long-Term Outcome after Spontaneous Intracerebral Hemorrhage

    Rodrigues, M. A., E Samarasekera, N., Lerpiniere, C., Perry, L. A., Moullaali, T. J., J M Loan, J., Wardlaw, J. M., Al-Shahi Salman, R. & Lothian Audit of the Treatment of Cerebral Haemorrhage Collaborators, 3 Nov 2020, In: Annals of Neurology.

    Research output: Contribution to journalArticlepeer-review

  19. Feasibility and diagnostic accuracy of using brain attenuation changes on CT to estimate time of ischemic stroke onset

    Mair, G., Alzahrani, A., Lindley, R. I., Sandercock, P. A. G. & Wardlaw, J. M., 30 Oct 2020, In: Neuroradiology.

    Research output: Contribution to journalArticlepeer-review

  20. Intensive versus guideline‐recommended blood pressure reduction in acute lacunar stroke with intravenous thrombolysis therapy: the ENCHANTED trial

    Zhou, Z., Xia, C., Carcel, C., Yoshimura, S., Wang, X., Delcourt, C., Malavera, A., Chen, X., Mair, G., Woodward, M., Chalmers, J., Demchuk, A. M., Lindley, R. I., Robinson, T. G., Parsons, M. W., Wardlaw, J. M. & Anderson, C. S., 17 Oct 2020, In: European Journal of Neurology.

    Research output: Contribution to journalArticlepeer-review

  21. Brain imaging abnormalities and outcome after acute ischaemic stroke: the ENCHANTED trial

    Delcourt, C., Wang, X., Zhou, Z., Wardlaw, J., Mair, G., Robinson, T., Chen, X., Yoshimura, S., Torii-yoshimura, T., Carcel, C., Calic, Z., Yong Tan, W., Malavera, A., Anderson, C. S. & Lindley, R. I., 14 Oct 2020, In: Journal of Neurology, Neurosurgery & Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  22. A new dawn of preventing dementia by preventing cerebrovascular diseases

    Pan, Y., Li, H., Wardlaw, J. M. & Wang, Y., 9 Oct 2020, In: British Medical Journal (BMJ). p. m3692

    Research output: Contribution to journalArticlepeer-review

  23. Clinical management of cerebral small vessel disease: a call for a holistic approach

    Clancy, U., Appleton, J. P., Arteaga Reyes, C., Doubal, F., Bath, P. M. & Wardlaw, J., 6 Oct 2020, In: Chinese Medical Journal.

    Research output: Contribution to journalArticlepeer-review

  24. The glymphatic system and its role in cerebral homeostasis

    Benveniste, H., Elkin, R., Heerdt, P., Koundal, S., Xue, Y., Lee, H., Wardlaw, J. & Tannenbaum, A., 1 Oct 2020, In: Journal of Applied Physiology.

    Research output: Contribution to journalArticlepeer-review

  25. Genetic correlations and genome-wide associations of cortical structure in general population samples of 22824 adults

    Hofer, E., Roshchupkin, G. V., Adams, H. H. H., Knol, M. J., Lin, H., Li, S., Zare, H., Ahmad, S., Armstrong, N. J., Satizabal, C. L., Bernard, M., Bis, J. C., Gillespie, N. A., Luciano, M., Mishra, A., Scholz, M., Teumer, A., Xia, R., Jian, X., Mosley, T. H. & 79 others, Saba, Y., Pirpamer, L., Seiler, S., Becker, J. T., Carmichael, O., Rotter, J. I., Psaty, B. M., Lopez, O. L., Amin, N., van der Lee, S. J., Yang, Q., Himali, J. J., Maillard, P., Beiser, A., DeCarli, C., Karama, S., Lewis, L., Harris, M., Bastin, M., Deary, I., Witte, A. V., Beyer, F., Loeffler, M., Mather, K. A., Schofield, P. R., Thalamuthu, A., Kwok, J. B. J., Wright, M. J., Ames, D., Trollor, J. N., Jiang, J., Brodaty, H., Wen, W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., Niessen, W. J., Wittfeld, K., Bülow, R., Völker, U., Pausova, Z., Pike, G. B., Maingault, S., Crivello, F., Tzourio, C., Amouyel, P., Mazoyer, B., Neale, M. C., Franz, C. E., Lyons, M. J., Panizzon, M. S., Andreassen, O. A., Dale, A. M., Logue, M. A., Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-Conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Stein, J. L., Thompson, P., Medland, S. E., Sachdev, P. S., Kremen, W. S., Wardlaw, J., Villringer, A., van Duijn, C., Grabe, H. J., Longstreth, W. T., Fornage, M., Paus, T., Debette, S., Ikram, M. A., Schmidt, H., Schmidt, R. & Seshadri, S., 22 Sep 2020, In: Nature Communications. 11, 4796 .

    Research output: Contribution to journalArticlepeer-review

  26. 4D flow MRI for non-invasive measurement of blood flow in the brain: A systematic review

    Morgan, A. G., Thrippleton, M. J., Wardlaw, J. M. & Marshall, I., 16 Sep 2020, In: Journal of Cerebral Blood Flow and Metabolism. p. 0271678X2095201

    Research output: Contribution to journalArticlepeer-review

  27. The Application of Optical Coherence Tomography Angiography in Cerebral Small Vessel Disease, Ischemic Stroke, and Dementia: A Systematic Review

    Zhang, J., Wiseman, S., Valdés-hernández, M. C., Doubal, F. N., Dhillon, B., Wu, Y. & Wardlaw, J. M., 10 Sep 2020, In: Frontiers in Neurology. 11, 1009.

    Research output: Contribution to journalArticlepeer-review

  28. Quantitative measurements of enlarged perivascular spaces in the brain are associated with retinal microvascular parameters in older community-dwelling subjects

    Ballerini, L., McGrory, S., Valdes Hernandez, M., Lovreglio, R., Pellegrini, E., MacGillivray, T., Muñoz Maniega, S., Henderson, R., Taylor, A., Bastin, M., Doubal, F., Trucco, E., Deary, I. & Wardlaw, J., 21 Aug 2020, In: Cerebral Circulation—Cognition and Behavior. 1, 100002.

    Research output: Contribution to journalArticlepeer-review

  29. Diffuse white matter loss in a transgenic rat model of cerebral amyloid angiopathy

    Lee, H., Xu, F., Liu, X., Koundal, S., Zhu, X., Davis, J., Yanez, D., Schrader, J., Stanisavljevic, A., Rothman, D. L., Wardlaw, J., Van Nostrand, W. E. & Benveniste, H., 13 Aug 2020, In: Journal of Cerebral Blood Flow and Metabolism. p. 0271678X2094422

    Research output: Contribution to journalArticlepeer-review

  30. Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID‐19 pandemic, now and in the future

    Mok, V. C. T., Pendlebury, S., Wong, A., Alladi, S., Au, L., Bath, P. M., Biessels, G. J., Chen, C., Cordonnier, C., Dichgans, M., Dominguez, J., Gorelick, P. B., Kim, S., Kwok, T., Greenberg, S. M., Jia, J., Kalaria, R., Kivipelto, M., Naegandran, K., Lam, L. C. W. & 15 others, Lam, B. Y. K., Lee, A. T. C., Markus, H. S., O'brien, J., Pai, M., Pantoni, L., Sachdev, P., Skoog, I., Smith, E. E., Srikanth, V., Suh, G., Wardlaw, J., Ko, H., Black, S. E. & Scheltens, P., 12 Aug 2020, In: Alzheimer's & Dementia.

    Research output: Contribution to journalArticlepeer-review

  31. Cilostazol for Secondary Prevention of Stroke and Cognitive Decline: Systematic Review and Meta-Analysis

    Mchutchison, C., Blair, G. W., Appleton, J. P., Chappell, F. M., Doubal, F., Bath, P. M. & Wardlaw, J. M., 10 Jul 2020, In: Stroke. 51, 8, p. 2374-2385

    Research output: Contribution to journalArticlepeer-review

  32. A Framework for Jointly Assessing and Reducing Imaging Artefacts Automatically Using Texture Analysis and Total Variation Optimisation for Improving Perivascular Spaces Quantification in Brain Magnetic Resonance Imaging

    Bernal, J., Valdés-hernández, M., Ballerini, L., Escudero, J., Jochems, A. C. C., Clancy, U., Doubal, F. N., Stringer, M. S., Thrippleton, M. J., Touyz, R. M. & Wardlaw, J. M., 8 Jul 2020, Conference on Medical Image Understanding and Analysis (MIUA) 2020. Springer, Vol. 1248. p. 171-183 Chapter 14. (Medical Image Understanding and Analysis; vol. 1248).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  33. Retinal Biomarkers Discovery for Cerebral Small Vessel Disease in an Older Population

    Ballerini, L., Fetit, A. E., Wunderlich, S., Lovreglio, R., Mcgrory, S., Valdes-hernandez, M., Macgillivray, T., Doubal, F., Deary, I. J., Wardlaw, J. & Trucco, E., 8 Jul 2020, Medical Image Understanding and Analysis. MIUA 2020. Communications in Computer and Information Science. Papież, B., Namburete, A., Yaqub, M. & Noble, J. (eds.). Springer, p. 400-409 Chapter 31. (Medical Image Understanding and Analysis; vol. 1248).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  34. Automatic Spatial Estimation of White Matter Hyperintensities Evolution in Brain MRI using Disease Evolution Predictor Deep Neural Networks

    Rachmadi, M. F., Valdés-hernández, M. D. C., Makin, S., Wardlaw, J. & Komura, T., 1 Jul 2020, In: Medical Image Analysis. 63, 101712.

    Research output: Contribution to journalArticlepeer-review

  35. Thrombolysis Outcomes in Acute Ischemic Stroke by Fluid-Attenuated Inversion Recovery Hyperintense Arteries

    Zhou, Z., Yoshimura, S., Delcourt, C., Lindley, R. I., You, S., Malavera, A., Torii-yoshimura, T., Carcel, C., Wang, X., Chen, X., Parsons, M. W., Demchuk, A. M., Wardlaw, J. M., Mair, G., Robinson, T. G., Chalmers, J., Xu, J. & Anderson, C. S., 17 Jun 2020, In: Stroke. 51, 7, p. 2240-2243

    Research output: Contribution to journalArticlepeer-review

  36. Aging-Sensitive Networks Within the Human Structural Connectome Are Implicated in Late-Life Cognitive Declines

    Madole, J. W., Ritchie, S. J., Cox, S. R., Buchanan, C. R., Valdés Hernández, M., Muñoz Maniega, S., Wardlaw, J. M., Harris, M. A. H., Bastin, M. E., Deary, I. J. & Tucker-Drob, E. M., 15 Jun 2020, In: Biological Psychiatry. N/A, p. 1-12

    Research output: Contribution to journalArticlepeer-review

  37. Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

    Armstrong, N. J., Mather, K. A., Sargurupremraj, M., Knol, M. J., Malik, R., Satizabal, C. L., Yanek, L. R., Wen, W., Gudnason, V. G., Dueker, N. D., Elliott, L. T., Hofer, E., Bis, J., Jahanshad, N., Li, S., Logue, M. A., Luciano, M., Scholz, M., Smith, A. V., Trompet, S. & 66 others, Vojinovic, D., Xia, R., Alfaro-almagro, F., Ames, D., Amin, N., Amouyel, P., Beiser, A. S., Brodaty, H., Deary, I. J., Fennema-notestine, C., Gampawar, P. G., Gottesman, R., Griffanti, L., Jack, C. R., Jenkinson, M., Jiang, J., Kral, B. G., Kwok, J. B., Lampe, L., C.m. Liewald, D., Maillard, P., Marchini, J., Bastin, M. E., Mazoyer, B., Pirpamer, L., Rafael Romero, J., Roshchupkin, G. V., Schofield, P. R., Schroeter, M. L., Stott, D. J., Thalamuthu, A., Trollor, J., Tzourio, C., Van Der Grond, J., Vernooij, M. W., Witte, V. A., Wright, M. J., Yang, Q., Morris, Z., Siggurdsson, S., Psaty, B., Villringer, A., Schmidt, H., Haberg, A. K., Van Duijn, C. M., Jukema, J. W., Dichgans, M., Sacco, R. L., Wright, C. B., Kremen, W. S., Becker, L. C., Thompson, P. M., Mosley, T. H., Wardlaw, J. M., Ikram, M. A., Adams, H. H. H., Seshadri, S., Sachdev, P. S., Smith, S. M., Launer, L., Longstreth, W., Decarli, C., Schmidt, R., Fornage, M., Debette, S. & Nyquist, P. A., 10 Jun 2020, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  38. Rationale and design of a longitudinal study of cerebral small vessel diseases, clinical and imaging outcomes in patients presenting with mild ischaemic stroke: Mild Stroke Study 3

    Clancy, U., Garcia, D. J., Stringer, M. S., Thrippleton, M. J., Valdés-hernández, M. C., Wiseman, S., Hamilton, O. K., Chappell, F. M., Brown, R., Blair, G. W., Hewins, W., Sleight, E., Ballerini, L., Bastin, M. E., Maniega, S. M., Macgillivray, T., Hetherington, K., Hamid, C., Arteaga, C., Morgan, A. G. & 7 others, Manning, C., Backhouse, E., Hamilton, I., Job, D., Marshall, I., Doubal, F. N. & Wardlaw, J. M., 5 Jun 2020, In: European Stroke Journal. p. 239698732092961

    Research output: Contribution to journalArticlepeer-review

  39. Age-Related Changes of Peak Width Skeletonized Mean Diffusivity (PSMD) Across the Adult Lifespan: A Multi-Cohort Study

    Beaudet, G., Tsuchida, A., Petit, L., Tzourio, C., Caspers, S., Schreiber, J., Pausova, Z., Patel, Y., Paus, T., Schmidt, R., Pirpamer, L., Sachdev, P. S., Brodaty, H., Kochan, N. A., Trollor, J. N., Wen, W., Armstrong, N. J., Deary, I., Bastin, M., Wardlaw, J. & 6 others, Muñoz Maniega, S., Witte, A. V., Villringer, A., Duering, M., Debette, S. & Mazoyer, B., 4 May 2020, In: Frontiers in psychiatry. 11, 342.

    Research output: Contribution to journalArticlepeer-review

  40. Intracranial haemodynamic relationships in patients with cerebral small vessel disease

    Blair, G., Thrippleton, M., Shi, Y., Hamilton, I., Stringer, M., Chappell, F., Dickie, D. A., Andrews, P., Marshall, I., Doubal, F. & Wardlaw, J., May 2020, In: Neurology. 94, 21

    Research output: Contribution to journalArticlepeer-review

  41. Protocol: The Lacunar Intervention Trial 2 (LACI-2). A trial of two repurposed licenced drugs to prevent progression of cerebral small vessel disease

    Wardlaw, J., Bath, P. M. W., Doubal, F., Heye, A., Sprigg, N., Woodhouse, L. J., Blair, G., Appleton, J., Cvoro, V., England, T., Hassan, A., John Werring, D. & Montgomery, A., 20 Apr 2020, In: European Stroke Journal. p. 239698732092011

    Research output: Contribution to journalArticlepeer-review

  42. Improving Clinical Detection of Acute Lacunar Stroke: Analysis From the IST-3

    Arba, F., Mair, G., Phillips, S., Sandercock, P. & Wardlaw, J. M., 9 Apr 2020, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  43. Relationship Between Venules and Perivascular Spaces in Sporadic Small Vessel Diseases

    Jochems, A. C. C., Blair, G. W., Stringer, M. S., Thrippleton, M. J., Clancy, U., Chappell, F. M., Brown, R., Jaime Garcia, D., Hamilton, O. K. L., Morgan, A. G., Marshall, I., Hetherington, K., Wiseman, S., Macgillivray, T., Valdés-hernández, M. C., Doubal, F. N. & Wardlaw, J. M., 8 Apr 2020, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  44. Clinical prognosis of FLAIR hyperintense arteries in ischaemic stroke patients: a systematic review and meta-analysis

    Zhou, Z., Malavera, A., Yoshimura, S., Delcourt, C., Mair, G., Al-shahi Salman, R., Demchuk, A. M., Wardlaw, J. M., Lindley, R. I. & Anderson, C. S., 26 Mar 2020, In: Journal of Neurology, Neurosurgery & Psychiatry. p. jnnp-2019-322625

    Research output: Contribution to journalArticlepeer-review

  45. Global and regional development of the human cerebral cortex: Molecular architecture and occupational aptitudes

    ENIGMA Consortium & neuroCHARGE Cognitive Working group, 20 Mar 2020, In: Cerebral Cortex. bhaa035.

    Research output: Contribution to journalArticlepeer-review

  46. The genetic architecture of the human cerebral cortex

    Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Ching, C. R. K., Mcmahon, M. A. B., Shatokhina, N., Zsembik, L. C. P., Thomopoulos, S. I., Zhu, A. H., Strike, L. T., Agartz, I., Alhusaini, S., Almeida, M. A. A., Alnæs, D., Amlien, I. K. & 31 others, Andersson, M., Ard, T., Armstrong, N. J., Ashley-koch, A., Atkins, J. R., Bernard, M., Brouwer, R. M., Buimer, E. E. L., Bülow, R., Bürger, C., Cannon, D. M., Chakravarty, M., Chen, Q., Cheung, J. W., Couvy-duchesne, B., Dale, A. M., Dalvie, S., De Araujo, T. K., De Zubicaray, G. I., De Zwarte, S. M. C., Den Braber, A., Doan, N. T., Dohm, K., Ehrlich, S., Harris, M. A., Luciano, M., Wardlaw, J. M., Doherty, C. P., Bastin, M. E., Deary, I. J. & Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)—Genetics working group, 20 Mar 2020, In: Science. 367, 6484, 14 p., eaay6690.

    Research output: Contribution to journalArticlepeer-review

  47. DNA methylation and brain structure and function across the life course: a systematic review

    Wheater, E. N. W., Stoye, D. Q., Cox, S. R., Wardlaw, J. M., Drake, A. J., Bastin, M. E. & Boardman, J. P., 6 Mar 2020, In: Neuroscience and Biobehavioral Reviews.

    Research output: Contribution to journalArticlepeer-review

  48. Polygenic architecture of human neuroanatomical diversity

    Biton, A., Traut, N., Poline, J. B., Aribsala, B., Bastin, M., Bülow, R., Cox, S., Deary, I., Fukunaga, M., Grabe, H. J., Hagenaars, S., Hashimoto, R., Kikuchi, M., Muñoz Maniega, S., Nauck, M., Royle, N., Teumer, A., Valdes Hernandez, M., Völker, U., Wardlaw, J. & 4 others, Wittfield, K., Yamamori, H., Bourgeron, T. & Toro, R., 28 Feb 2020, In: Cerebral Cortex. bhz241.

    Research output: Contribution to journalArticlepeer-review

  49. Publisher Correction: Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

    Koundal, S., Elkin, R., Nadeem, S., Xue, Y., Constantinou, S., Sanggaard, S., Liu, X., Monte, B., Xu, F., Nostrand, W. V., Nedergaard, M., Lee, H., Wardlaw, J., Benveniste, H. & Tannenbaum, A., 27 Feb 2020, In: Scientific Reports. 10, 1

    Research output: Contribution to journalArticle

  50. Perivascular spaces in the brain: anatomy, physiology and pathology

    Wardlaw, J. M., Benveniste, H., Nedergaard, M., Zlokovic, B. V., Mestre, H., Lee, H., Doubal, F. N., Brown, R., Ramirez, J., Macintosh, B. J., Tannenbaum, A., Ballerini, L., Rungta, R. L., Boido, D., Sweeney, M., Montagne, A., Charpak, S., Joutel, A., Smith, K. J. & Black, S. E., 24 Feb 2020, In: Nature Reviews Neurology. 16, 3, p. 137-153 17 p.

    Research output: Contribution to journalArticlepeer-review

  51. Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

    Harris, S., Cox, S., Bell, S., Marioni, R., Prins, B. P., Pattie, A., Corley, J., Muñoz Maniega, S., Valdes Hernandez, M., Morrison, Z., John, S. L., Bronson, P. G., Tucker-Drob, E. M., Starr, J., Bastin, M., Wardlaw, J., Butterworth, A. S. & Deary, I., 10 Feb 2020, In: Nature Communications. 11, 800.

    Research output: Contribution to journalArticlepeer-review

  52. Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

    Kounda, S., Elkin, R., Nadeem, S., Xue, Y., Constantinou, S., Sanggaard, S., Liu, X., Monte, B., Xu, F., Van Nostrand, W., Nedergaard, M., Lee, H., Wardlaw, J., Benveniste, H. & Tannenbaum, A., 6 Feb 2020, In: Scientific Reports. 10, 1

    Research output: Contribution to journalArticlepeer-review

  53. Fluctuating asymmetry in brain structure and general intelligence in 73-Year-olds

    Moodie, J. E., Ritchie, S., Cox, S., Harris, M., Muñoz Maniega, S., Valdes Hernandez, M., Pattie, A., Corley, J., Bastin, M., Starr, J., Wardlaw, J. & Deary, I., 31 Jan 2020, In: Intelligence. 78, 101407.

    Research output: Contribution to journalArticlepeer-review

  54. Analysis of spatial spectral features of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease

    Bernal Moyano, J., Valdes Hernandez, M., Escudero, J., Armitage, P., Makin, S., Touyz, R. M. & Wardlaw, J., 24 Jan 2020, Medical Image Understanding and Analysis. MIUA 2019. Communications in Computer and Information Science. Springer, Vol. 1065.

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  55. Cerebral small vessel disease: Potential interventions for prevention and treatment

    Blair, G., Appleton, J. P., Wardlaw, J. & Bath, P., 15 Jan 2020, Stroke in the Older Person. Oxford University Press

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  56. Small vessel disease is associated with altered cerebrovascular pulsatility but not resting cerebral blood flow

    Shi, Y., Thrippleton, M. J., Blair, G. W., Dickie, D. A., Marshall, I., Hamilton, I., Doubal, F. N., Chappell, F. & Wardlaw, J. M., 1 Jan 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40, 1, p. 85-99 15 p.

    Research output: Contribution to journalArticlepeer-review

  57. Sleep and brain morphological changes in the eighth decade of life

    Aribisala, B. S., Riha, R. L., Valdes Hernandez, M., Maniega, S. M., Cox, S., Radakovic, R., Taylor, A., Pattie, A., Corley, J., Redmond, P., Bastin, M. E., Starr, J., Deary, I. & Wardlaw, J. M., Jan 2020, In: Sleep medicine. 65

    Research output: Contribution to journalArticlepeer-review

  58. White matter hyperintensities mediate the association between blood-brain barrier leakage and information processing speed

    Freeze, W. M., Jacobs, H. I. L., De Jong, J. J., Verheggen, I. C. M., Gronenschild, E. H. B. M., Palm, W. M., Hoff, E. I., Wardlaw, J. M., Jansen, J. F. A., Verhey, F. R. & Backes, W. H., Jan 2020, In: Neurobiology of Aging. 85

    Research output: Contribution to journalArticlepeer-review

  59. 2019
  60. Imaging markers of small vessel disease and ‘brain frailty’ and outcomes in acute stroke

    Appleton, J. P., Woodhouse, L., Adami, A., Becker, J. L., Berge, E., Cala, L. A., Casado, A. M., Caso, V., Christensen, H., Dineen, R. A., Gommans, J., Koumellis, P., Szatmari, S., Sprigg, N., Bath, P. M., Wardlaw, J. & ENOS Investigators, 27 Dec 2019, In: Neurology.

    Research output: Contribution to journalArticlepeer-review

  61. Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group

    Jia, T., Chu, C., Liu, Y., van Dongen, J., Papastergios, E., Armstrong, N. J., Bastin, M. E., Carrillo-roa, T., den Braber, A., Harris, M., Jansen, R., Liu, J., Luciano, M., Ori, A. P. S., Roiz-Santianez, R., Ruggeri, B., Sarkisyan, D., Shin, J., Sungeun, K., Tordesillas-Gutierrez, D. & 62 others, Van't Ent, D., Ames, D., Artiges, E., Bakalkin, G., Banaschewski, T., Bokde, A. L. W., Brodaty, H., Bromberg, U., Brouwer, R. M., Büchel, C., Quinlan, E. B., Cahn, W., de Zubicaray, G. I., Ehrlich, S., Ekström, T. J., Flor, H., Fröhner, J. H., Frouin, V., Garavan, H., Gowland, P. A., Heinz, A., Hoare, J., Ittermann, B., Jahanshad, N., Jiang, J., Kwok, J. B. J., Martin, N. G., Martinot, J-L., Mather, K. A., McMahon, K. L., Mcrae, A. F., Nees, F., Papadopoulos Orfanos, D., Paus, T., Poustka, L., Sämann, P. G., Schofield, P. R., Smolka, M. N., Stein, D. J., Strike, L. T., Teeuw, J., Thalamuthu, A., Trollor, J. N., Walter, H., Wardlaw, J. M., Wen, W., Whelan, R., Apostolova, L. G., Binder, E. B., Boomsma, D., Calhoun, V. D., Crespo-Facorro, B., Deary, I. J., Hulshoff Pol, H. E., Ophoff, R. A., Pausova, Z., Sachdev, P. S., Saykin, A. J., Wright, M. J., Thompson, P. M., Schumann, G. & Desrivières, S., 6 Dec 2019, In: Molecular Psychiatry. N/A, p. 1-12

    Research output: Contribution to journalArticlepeer-review

  62. An epigenetic predictor of death captures multi-modal measures of brain health

    Hillary, R. F., Stevenson, A. J., Cox, S. R., McCartney, D. L., Harris, S. E., Seeboth, A., Higham, J., Sproul, D., Taylor, A. M., Redmond, P., Corley, J., Pattie, A., del C. Valdés Hernández, M., Muñoz-Maniega, S., Bastin, M. E., Wardlaw, J. M., Horvath, S., Ritchie, C. W., Spires-Jones, T. L., McIntosh, A. M. & 3 others, Evans, K. L., Deary, I. J. & Marioni, R. E., 3 Dec 2019, In: Molecular Psychiatry. N/A, p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

  63. Retinal microvascular features and cognitive change in the Lothian Birth Cohort 1936

    McGrory, S., Ballerini, L., Okely, J., Ritchie, S., Doubal, F., Doney, A. S. F., Starr, J., MacGillivray, T., Trucco, E., Wardlaw, J. & Deary, I., Dec 2019, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 11, p. 500-509 10 p.

    Research output: Contribution to journalArticlepeer-review

  64. Genetic architecture of subcortical brain structures in 38,851 individuals

    Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., Van Der Lee, S. J., Yang, J., Yanek, L. R., Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., Den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C-Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., De Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., Van Eijk, K. R., Cavalleri, G. L., Van Der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., Van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B-C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J-J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., Van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., Van Tol, M-J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., Van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J-L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., Van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., Van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., Destefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., Van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., Decarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., 30 Nov 2019, In: Nature Genetics. 51, 11, p. 1624–1636 13 p.

    Research output: Contribution to journalArticlepeer-review

  65. Limited One-time Sampling Irregularity Map (LOTS-IM) for Automatic Unsupervised Assessment of White Matter Hyperintensities and Multiple Sclerosis Lesions in Structural Brain Magnetic Resonance Images

    Rachmadi, M. F., Del C. Valdés-hernández, M., Li, H., Guerrero, R., Meijboom, R., Wiseman, S., Waldman, A., Zhang, J., Rueckert, D., Wardlaw, J. & Komura, T., 27 Nov 2019, In: Computerized Medical Imaging and Graphics. 79, 101685.

    Research output: Contribution to journalArticlepeer-review

  66. Brain atrophy in cerebral small vessel diseases: Extent, consequences, technical limitations and perspectives: The HARNESS initiative

    De Guio, F., Duering, M., Fazekas, F., De Leeuw, F., Greenberg, S. M., Pantoni, L., Aghetti, A., Smith, E. E., Wardlaw, J. & Jouvent, E., 20 Nov 2019, In: Journal of Cerebral Blood Flow and Metabolism. p. 0271678X1988896

    Research output: Contribution to journalReview articlepeer-review

  67. Analysis of dynamic texture and spatial spectral descriptors of dynamic contrast-enhanced brain magnetic resonance images for studying small vessel disease

    Bernal, J., Valdés-hernández, M. D. C., Escudero, J., Viksne, L., Heye, A. K., Armitage, P. A., Makin, S., Touyz, R. M. & Wardlaw, J. M., 13 Nov 2019, In: Magnetic Resonance Imaging.

    Research output: Contribution to journalArticlepeer-review

  68. Profile of and risk factors for poststroke cognitive impairment in diverse ethno-regional groups

    for the Stroke and Cognition (STROKOG) Collaboration, 11 Nov 2019, In: Neurology. p. 10.1212/WNL.0000000000008612

    Research output: Contribution to journalArticlepeer-review

  69. Predictors of Lesion Cavitation After Recent Small Subcortical Stroke

    Gattringer, T., Valdes Hernandez, M., Heye, A., Armitage, P. A., Makin, S., Chappell, F., Pinter, D., Doubal, F., Enzinger, C., Fazekas, F. & Wardlaw, J. M., 8 Nov 2019, In: Translational Stroke Research.

    Research output: Contribution to journalArticlepeer-review

  70. Predicting the Evolution of White Matter Hyperintensities in Brain MRI using Generative Adversarial Networks and Irregularity Map

    Rachmadi, M., Valdes Hernandez, M., Makin, S., Wardlaw, J. & Komura, T., 10 Oct 2019, Medical Image Computing and Computer Assisted Intervention – MICCAI 2019. Shen, D., Liu, T., Peters, T. M., Staib, L. H., Essert, C., Zhou, S., Yap, P-T. & Khan, A. (eds.). Springer, p. 146–154 9 p. (Lecture Notes in Computer Science (LNCS); vol. 11766).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  71. Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage: Data From the RIGHT-2 Trial

    Bath, P. M., Woodhouse, L. J., Krishnan, K., Appleton, J. P., Anderson, C. S., Berge, E., Cala, L., Dixon, M., England, T. J., Godolphin, P. J., Hepburn, T., Mair, G., Montgomery, A. A., Phillips, S. J., Potter, J., Price, C. I., Randall, M., Robinson, T. G., Roffe, C., Rothwell, P. M. & 7 others, Sandset, E. C., Sanossian, N., Saver, J. L., Siriwardena, A. N., Venables, G., Wardlaw, J. M. & Sprigg, N., 7 Oct 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  72. Mechanical thrombectomy in patients with acute ischemic stroke: A cost-effectiveness and value of implementation analysis

    Heggie, R., Wu, O., White, P., Ford, G. A., Wardlaw, J., Brown, M. M., Clifton, A. & Muir, K. W., 30 Sep 2019, In: International Journal of Stroke. p. 174749301987965

    Research output: Contribution to journalArticlepeer-review

  73. Observer Agreement on Computed Tomography Perfusion Imaging in Acute Ischemic Stroke

    El-tawil, S., Mair, G., Huang, X., Sakka, E., Palmer, J., Ford, I., Kalra, L., Wardlaw, J. & Muir, K. W., 25 Sep 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  74. Special topic section: linkages among cerebrovascular, cardiovascular, and cognitive disorders: Preventing dementia by preventing stroke: The Berlin Manifesto

    Hachinski, V., Einhäupl, K., Ganten, D., Alladi, S., Brayne, C., Stephan, B. C. M., Sweeney, M. D., Zlokovic, B., Iturria-medina, Y., Iadecola, C., Nishimura, N., Schaffer, C. B., Whitehead, S. N., Black, S. E., Østergaard, L., Wardlaw, J., Greenberg, S., Friberg, L., Norrving, B., Rowe, B. & 6 others, Joanette, Y., Hacke, W., Kuller, L., Dichgans, M., Endres, M. & Khachaturian, Z. S., 22 Sep 2019, In: International Journal of Stroke. p. 174749301987191

    Research output: Contribution to journalArticlepeer-review

  75. Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial

    Van Der Worp, H. B., Macleod, M. R., Bath, P. M., Bathula, R., Christensen, H., Colam, B., Cordonnier, C., Demotes-mainard, J., Durand-zaleski, I., Gluud, C., Jakobsen, J. C., Kallmünzer, B., Kollmar, R., Krieger, D. W., Lees, K. R., Michalski, D., Molina, C., Montaner, J., Roine, R. O., Petersson, J. & 8 others, Perry, R., Sprigg, N., Staykov, D., Szabo, I., Vanhooren, G., Wardlaw, J. M., Winkel, P. & Schwab, S., 1 Sep 2019, In: European Stroke Journal. 4, 3, p. 254-262

    Research output: Contribution to journalArticlepeer-review

  76. Brain peak width of skeletonised mean diffusivity (PSMD) and cognitive function in later life

    Deary, I., Ritchie, S. J., Muñoz Maniega, S., Cox, S., Valdes Hernandez, M., Luciano, M., Starr, J., Wardlaw, J. & Bastin, M., 26 Jul 2019, In: Frontiers in psychiatry. 10, 524.

    Research output: Contribution to journalArticlepeer-review

  77. Associations between vascular risk factors and brain MRI indices in UK Biobank

    Cox, S. R., Lyall, D. M., Ritchie, S. J., Bastin, M. E., Harris, M. A., Buchanan, C. R., Fawns-Ritchie, C., Barbu, M., de Nooij, L., Reus, L. M., Alloza, C., Shen, X., Neilson, E., Alderson, H. L., Hunter, S., Liewald, D. C., Whalley, H. C., McIntosh, A. M., Lawrie, S. M., Pell, J. P. & 4 others, Tucker-Drob, E. M., Wardlaw, J. M., Gale, C. R. & Deary, I. J., 21 Jul 2019, In: European Heart Journal. 40, 28, p. 2290–2300 11 p.

    Research output: Contribution to journalArticlepeer-review

  78. Preventing dementia by preventing stroke: The Berlin Manifesto

    Hachinski, V., Einhäupl, K., Ganten, D., Alladi, S., Brayne, C., Stephan, B. C. M., Sweeney, M. D., Zlokovic, B., Iturria-medina, Y., Iadecola, C., Nishimura, N., Schaffer, C. B., Whitehead, S. N., Black, S. E., Østergaard, L., Wardlaw, J., Greenberg, S., Friberg, L., Norrving, B., Rowe, B. & 6 others, Joanette, Y., Hacke, W., Kuller, L., Dichgans, M., Endres, M. & Khachaturian, Z. S., 18 Jul 2019, In: Alzheimer's & Dementia. 15, 7, p. 961-984

    Research output: Contribution to journalArticlepeer-review

  79. Lowering blood pressure after acute intracerebral haemorrhage: protocol for a systematic review and meta-analysis using individual patient data from randomised controlled trials participating in the Blood Pressure in Acute Stroke Collaboration (BASC)

    Moullaali, T. J., Wang, X., Woodhouse, L. J., Law, Z. K., Delcourt, C., Sprigg, N., Krishnan, K., Robinson, T. G., Wardlaw, J. M., Al-shahi Salman, R., Berge, E., Sandset, E. C., Anderson, C. S. & Bath, P. M., 16 Jul 2019, In: BMJ Open. 9, 7, e030121.

    Research output: Contribution to journalArticlepeer-review

  80. Effects of Isosorbide Mononitrate and/or Cilostazol on Hematological Markers, Platelet Function, and Hemodynamics in Patients With Lacunar Ischaemic Stroke: Safety Data From the Lacunar Intervention-1 (LACI-1) Trial

    Appleton, J. P., Blair, G. W., Flaherty, K., Law, Z. K., May, J., Woodhouse, L. J., Doubal, F., Sprigg, N., Bath, P. M. & Wardlaw, J. M., 3 Jul 2019, In: Frontiers in Neurology. 10

    Research output: Contribution to journalArticlepeer-review

  81. Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

    Wilson, D., Ambler, G., Lee, K-J., Lim, J-S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sánchez, L., Martínez-Domeño, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K. & 61 others, Wong, A., Kim, Y. D., Song, T-J., Schrooten, M., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Tanriverdi, Z., Bornstein, N. M., Assayag, E. B., Hallevi, H., Tanaka, J., Hara, H., Coutts, S. B., Hert, L., Polymeris, A., Seiffge, D. J., Lyrer, P., Algra, A., Kappelle, J., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Mattle, H. P., Panos, L. D., Mas, J-L., Legrand, L., Karayiannis, C., Phan, T., Gunkel, S., Christ, N., Abrigo, J., Leung, T., Chu, W., Chappell, F., Makin, S., Hayden, D., Williams, D. J., Kooi, M. E., Kvan Dam-Nolen, D. H., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Maaijwee, N., Guevarra, C., Yatawara, C., Mendyk, A-M., Delmaire, C., Köhler, S., van Oostenbrugge, R., Zhou, Y., Xu, C., Hilal, S., Wardlaw, J. M., Jung, S., Sakka, E., Perry, R., Mitchell, J. & Microbleeds International Collaborative Network, 1 Jul 2019, In: Lancet Neurology. 18, 7, p. 653-665 13 p.

    Research output: Contribution to journalArticlepeer-review

  82. Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: Subgroup analyses of the RESTART randomised, open-label trial

    Al-Shahi Salman, R., Minks, D. P., Mitra, D., Rodrigues, M. A., Bhatnagar, P., du Plessis, J. C., Joshi, Y., Dennis, M. S., Murray, G. D., Newby, D. E., Sandercock, P. A. G., Sprigg, N., Stephen, J., Sudlow, C. L. M., Werring, D. J., Whiteley, W. N., Wardlaw, J. M., White, P. M. & RESTART collaboration, 1 Jul 2019, In: Lancet Neurology. 18, 7, p. 643-652 10 p.

    Research output: Contribution to journalArticlepeer-review

  83. Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial

    Wardlaw, J. & RESTART collaboration, 29 Jun 2019, In: The Lancet. 393, 10191, p. 2613-2623 11 p.

    Research output: Contribution to journalArticlepeer-review

  84. Reaction time variability and brain white matter integrity

    Booth, T., Dykiert, D., Corley, J., Gow, A., Morrison, Z., Munoz-Maniega, S., Royle, N., Valdes Hernandez, M., Starr, J., Penke, L., Bastin, M., Wardlaw, J. & Deary, I., 28 Jun 2019, In: Neuropsychology. 33, 5, p. 642-657

    Research output: Contribution to journalArticlepeer-review

  85. Perivascular spaces in the centrum semiovale at the beginning of the 8th decade of life: Effect on cognition and associations with mineral deposition

    Valdes Hernandez, M., Ballerini, L., Glatz, A., Munoz-Maniega, S., Gow, A., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., 27 Jun 2019, In: Brain imaging and behavior.

    Research output: Contribution to journalArticlepeer-review

  86. Factors associated with potentially serious incidental findings and with serious final diagnoses on multi-modal imaging in the UK Biobank Imaging Study: a prospective cohort study

    Sudlow, C., Gibson, L., Nolan, J., Littlejohns, T. J., Mathieu, E., Garratt, S., Doherty, N., Petersen, S. E., Harvey, N. C. W., Sellors, J., Allen, N. E., Wardlaw, J. & Jackson, C., 17 Jun 2019, In: PLoS ONE. 16, 6, e0218267.

    Research output: Contribution to journalArticlepeer-review

  87. Stability of estimated premorbid cognitive ability over time after minor stroke and its relationship with post-stroke cognitive ability

    McHutchison, C. A., Chappell, F. M., Makin, S., Shuler, K., Wardlaw, J. M. & Cvoro, V., 22 May 2019, In: Brain Sciences. 9, 5, p. 1-15 117.

    Research output: Contribution to journalArticlepeer-review

  88. Cortical thickness, white matter hyperintensities, and cognition after stroke

    Dickie, D. A., Gardner, K., Wagener, A., Wyss, A., Arba, F., Wardlaw, J. M. & Dawson, J., 14 May 2019, In: International Journal of Stroke. p. 174749301985129

    Research output: Contribution to journalArticlepeer-review

  89. Small vessel disease: mechanisms and clinical implications

    Wardlaw, J., Smith, C. & Dichgans, M., 13 May 2019, In: Lancet Neurology.

    Research output: Contribution to journalReview articlepeer-review

  90. Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial

    Blair, G. W., Appleton, J. P., Flaherty, K., Doubal, F., Sprigg, N., Dooley, R., Richardson, C., Hamilton, I., Law, Z. K., Shi, Y., Stringer, M. S., Thrippleton, M. J., Boyd, J., Shuler, K., Bath, P. M. & Wardlaw, J. M., 1 May 2019, In: EClinicalMedicine. 11, p. 34-43 10 p.

    Research output: Contribution to journalArticlepeer-review

  91. Quantifying BBB leakage in small vessel disease: review and consensus recommendations

    Thrippleton, M., Backes, W. H., Sourbron, S., Ingrisch, M., van Osch, M. J. P., Dichgans, M., Fazekas, F., Ropele, S., Frayne, R., van Oostenbrugge, R. J., Smith, E. E. & Wardlaw, J., 25 Apr 2019, In: Alzheimer's & Dementia.

    Research output: Contribution to journalArticlepeer-review

  92. Are morphologic features of recent small subcortical infarcts related to specific etiologic aspects?

    Eppinger, S., Gattringer, T., Nachbaur, L., Fandler, S., Pirpamer, L., Ropele, S., Wardlaw, J., Enzinger, C. & Fazekas, F., 22 Apr 2019, In: Therapeutic Advances in Neurological Disorders.

    Research output: Contribution to journalArticlepeer-review

  93. Retinal microvasculature and cerebral small vessel disease in the Lothian Birth Cohort 1936 and Mild Stroke Study

    McGrory, S., Ballerini, L., Doubal, F. N., Staals, J., Allerhand, M., Valdes Hernandez, M. D. C., Wang, X., MacGillivray, T., Doney, A. S. F., Dhillon, B., Starr, J. M., Bastin, M. E., Trucco, E., Deary, I. J. & Wardlaw, J. M., 19 Apr 2019, In: Scientific Reports. 9, 11 p., 6320.

    Research output: Contribution to journalArticlepeer-review

  94. The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: design and multicenter pilot study

    Weaver, N., Zhao, L., Biesbroek, J. M., Kuijf, H. J., Aben, H. P., Bae, H-J., Caballero, M. Á. A., Chappell, F., Chen, C. P. L. H., Dichgans, M., Duering, M., Georgakis, M. K., van der Giessen, R. S., Gyanwalij, B., Hamilton, O., Hilalj, S., vom Hofe, E. M., De Kort, P. L. M., Koudstaal, P. J., Lam, B. Y. K. & 12 others, Lim, J-S., Makin, S., Mok, V. C. T., Shi, L., Valdes Hernandez, M., Venketasubramanian, N., Wardlaw, J., Wollenweber, F. A., Wong, A., Xue, X., Meta VCI Map Consortium & Biessels, G. J., 12 Apr 2019, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalArticlepeer-review

  95. Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke

    McHutchison, C. A., Cvoro, V., Makin, S., Chappell, F. M., Shuler, K. & Wardlaw, J. M., 9 Apr 2019, In: Journal of Neurology, Neurosurgery & Psychiatry. 90, 4, p. 436-443 8 p.

    Research output: Contribution to journalArticlepeer-review

  96. Combining Neurovascular and Neurodegenerative Magnetic Resonance Imaging Measures in Stroke

    Wyss, A., Dawson, J., Arba, F., Wardlaw, J. M., Dickie, D. A., Diener, H. C., Algra, A., Davis, S., Hankey, G., Lees, K. R., Ovbiagele, B. & Weir, C., 8 Apr 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  97. Percutaneous Vascular Interventions Versus Intravenous Thrombolytic Treatment for Acute Ischemic Stroke

    Lindekleiv, H., Bruins Slot, K. M. H., Wardlaw, J. M. & Berge, E., 2 Apr 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  98. Clinical diagnosis of TIA or minor stroke and prognosis in patients with neurological symptoms: A rapid access clinic cohort

    Sudlow, C., Graham, C., Bailey, D., Hart, S., Hutchison, A., Sandercock, P., Doubal, F., Farrall, A., Wardlaw, J., Dennis, M. & Whiteley, W., 19 Mar 2019, In: PLoS ONE. 14, 3, e0210452.

    Research output: Contribution to journalArticlepeer-review

  99. It is safe to use transdermal glyceryl trinitrate to lower blood pressure in patients with acute ischaemic stroke with carotid stenosis

    Appleton, J. P., Woodhouse, L. J., Belcher, A., Bereczki, D., Berge, E., Caso, V., Chang, H. M., Christensen, H. K., Collins, R., Gommans, J., Laska, A. C., Ntaios, G., Ozturk, S., Sare, G. M., Szatmari, S., Wang, Y., Wardlaw, J. M., Sprigg, N. & Bath, P. M., 19 Mar 2019, In: Stroke and Vascular Neurology. 4, 1, p. 28-35

    Research output: Contribution to journalArticlepeer-review

  100. WMH and long-term outcomes in ischemic stroke: A systematic review and meta-analysis

    Georgakis, M. K., Duering, M., Wardlaw, J. M. & Dichigans, M., 19 Mar 2019, In: Neurology. 92, 12, p. e1298-e1308 11 p.

    Research output: Contribution to journalArticlepeer-review

  101. Identification of the presence of ischaemic stroke lesions by means of texture analysis on brain magnetic resonance images

    Ortiz-ramón, R., Valdés Hernández, M. D. C., González-castro, V., Makin, S., Armitage, P. A., Aribisala, B. S., Bastin, M. E., Deary, I. J., Wardlaw, J. M. & Moratal, D., 16 Mar 2019, In: Computerized Medical Imaging and Graphics. 74, p. 12-24

    Research output: Contribution to journalArticlepeer-review

  102. Association between Striatal Brain Iron Deposition, Microbleeds and Cognition 1 Year After a Minor Ischaemic Stroke

    Valdés Hernández, M., Case, T., Chappell, F., Glatz, A., Makin, S., Doubal, F. & Wardlaw, J., 14 Mar 2019, In: International Journal of Molecular Sciences. 20, 6, p. 1293

    Research output: Contribution to journalArticlepeer-review

  103. Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): An ambulance-based, randomised, sham-controlled, blinded, phase 3 trial

    The RIGHT-2 Investigators, 9 Mar 2019, In: The Lancet. 393, 10175, p. 1009-1020 12 p.

    Research output: Contribution to journalArticlepeer-review

  104. A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

    Fetit, A. E., Doney, A. S., Hogg, S., Wang, R., Macgillivray, T., Wardlaw, J. M., Doubal, F. N., Mckay, G. J., Mckenna, S. & Trucco, E., 5 Mar 2019, In: Scientific Reports. 9, 1, p. 3591

    Research output: Contribution to journalArticlepeer-review

  105. Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): An international randomised, open-label, blinded-endpoint phase 3 trial

    Anderson, C. S., Huang, Y., Lindley, R. I., Chen, X., Arima, H., Chen, G., Li, Q., Billot, L., Delcourt, C., Bath, P. M., Broderick, J. P., Demchuk, A. M., Donnan, G. A., Durham, A. C., Lavados, P. M., Lee, T. H., Levi, C., Martins, SO., Olavarria, V. V., Pandian, J. D. & 15 others, Parsons, M. W., Pontes-Neto, O. M., Ricci, S., Sato, S., Sharma, V. K., Silva, F., Song, L., Thang, NH., Wardlaw, J. M., Wang, J-G., Wang, X., Woodward, M., Chalmers, J., Robinson, T. G. & ENCHANTED Investigators and Coordinators, 2 Mar 2019, In: The Lancet. 393, 10174, p. 877-888 12 p.

    Research output: Contribution to journalArticlepeer-review

  106. Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration

    Smith, E. E., Biessels, G. J., De Guio, F., De Leeuw, F. E., Duchesne, S., Düring, M., Frayne, R., Ikram, M. A., Jouvent, E., Macintosh, B. J., Thrippleton, M. J., Vernooij, M. W., Adams, H., Backes, W. H., Ballerini, L., Black, S. E., Chen, C., Corriveau, R., Decarli, C., Greenberg, S. M. & 29 others, Gurol, M. E., Ingrisch, M., Job, D., Lam, B. Y. K., Launer, L. J., Linn, J., Mccreary, C. R., Mok, V. C. T., Pantoni, L., Pike, G. B., Ramirez, J., Reijmer, Y. D., Romero, J. R., Ropele, S., Rost, N. S., Sachdev, P. S., Scott, C. J. M., Seshadri, S., Sharma, M., Sourbron, S., Steketee, R. M. E., Swartz, R. H., Van Oostenbrugge, R., Van Osch, M., Van Rooden, S., Viswanathan, A., Werring, D., Dichgans, M. & Wardlaw, J. M., 26 Feb 2019, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 11, p. 191-204

    Research output: Contribution to journalArticlepeer-review

  107. Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: A systematic review and meta-analysis

    Firdaus Francis, F., Ballerini, L. & Wardlaw, J., 14 Feb 2019, In: International Journal of Stroke.

    Research output: Contribution to journalReview articlepeer-review

  108. MRI Relaxometry for Quantitative Analysis of USPIO Uptake in Cerebral Small Vessel Disease

    Thrippleton, M., Blair, G., Valdes-hernandez, M., Glatz, A., Semple, S., Doubal, F., Vesey, A., Marshall, I., Newby, D. & Wardlaw, J., 12 Feb 2019, In: International Journal of Molecular Sciences. 20, 3, p. 776

    Research output: Contribution to journalArticlepeer-review

  109. Manually-parcellated gyral data accounting for all known anatomical variability

    Mikhael, S., Mair, G., Valdes Hernandez, M., Hoogendoorn, C., Wardlaw, J., Bastin, M. & Pernet, C. R., 29 Jan 2019, In: Scientific Data. 6, 12 p., 190001.

    Research output: Contribution to journalArticlepeer-review

  110. Brain morphometry and longitudinal relaxation time of spontaneously hypertensive rats (SHR) in early and intermediate stages of hypertension investigated by 3D VFA-SPGR MRI

    Koundal, S., Liu, X., Sanggaard, S., Mortensen, K., Wardlaw, J., Nedergaard, M., Benveniste, H. & Lee, H., 26 Jan 2019, In: Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  111. Effect of Glyceryl Trinitrate on Hemodynamics in Acute Stroke: Data From the ENOS Trial

    ENOS Investigators, 10 Jan 2019, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  112. Convolutional Neural Networks for Direct Inference of Pharmacokinetic Parameters: Application to Stroke Dynamic Contrast-Enhanced MRI

    Ulas, C., Das, D., Thrippleton, M. J., Valdés Hernández, M. D. C., Armitage, P. A., Makin, S. D., Wardlaw, J. M. & Menze, B. H., 8 Jan 2019, In: Frontiers in Neurology. 9

    Research output: Contribution to journalArticlepeer-review

  113. Vascular contributions to cognitive impairment and dementia: Research consortia that focus on etiology and treatable targets to lessen the burden of dementia worldwide

    Gladman, J. T., Corriveau, R. A., Debette, S., Dichgans, M., Greenberg, S. M., Sachdev, P. S., Wardlaw, J. M. & Biessels, G. J., 1 Jan 2019, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, C, p. 789-796

    Research output: Contribution to journalArticlepeer-review

  114. Stroke research in 2018: extended time windows, refined benefit, and lifestyle prevention targets

    Wardlaw, J. M. & Bath, P. M., Jan 2019, In: Lancet Neurology. 18, 1, p. 2-3

    Research output: Contribution to journalComment/debate

  115. Vascular dysfunction – the disregarded partner of Alzheimer’s disease

    Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M. & 49 others, Markus, H. S., Salman, R. A., Allan, S. M., Quinn, T. J., Kalaria, R. N., Werring, D. J., Carare, R. O., Touyz, R. M., Williams, S. C. R., Moskowitz, M. A., Katusic, Z. S., Lutz, S. E., Lazarov, O., Minshall, R. D., Rehman, J., Davis, T. P., Wellington, C. L., González, H. M., Yuan, C., Lockhart, S. N., Hughes, T. M., Chen, C. L. H., Sachdev, P., O'Brien, J. T., Skoog, I., Pantoni, L., Gustafson, D. R., Biessels, G. J., Wallin, A., Smith, E. E., Mok, V., Wong, A., Passmore, P., Barkof, F., Muller, M., Breteler, M. M. B., Román, G. C., Hamel, E., Seshadri, S., Gottesman, R. F., van Buchem, M. A., Arvanitakis, Z., Schneider, J. A., Drewes, L. R., Hachinski, V., Finch, C. E., Toga, A. W., Wardlaw, J. M. & Zlokovic, B. V., Jan 2019, In: Alzheimer's & Dementia. 15, 1, p. 158-167 10 p.

    Research output: Contribution to journalComment/debatepeer-review

  116. Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

    Chauhan, G., Adams, H. H. H., Satizabal, C. L., Bis, J. C., Teumer, A., Sargurupremraj, M., Hofer, E., Trompet, S., Hilal, S., Smith, A. V., Jian, X., Malik, R., Traylor, M., Pulit, S. L., Amouyel, P., Mazoyer, B., Zhu, Y., Kaffashian, S., Schilling, S., Beecham, G. W. & 130 others, Montine, T. J., Schellenberg, G. D., Kjartansson, O., Guðnason, V., Knopman, D. S., Griswold, M. E., Windham, B. G., Gottesman, R. F., Mosley, T. H., Schmidt, R., Saba, Y., Schmidt, H., Takeuchi, F., Yamaguchi, S., Nabika, T., Kato, N., Rajan, K. B., Aggarwal, N. T., De Jager, P. L., Evans, D. A., Psaty, B. M., Rotter, J. I., Rice, K., Lopez, O. L., Liao, J., Chen, C., Cheng, C., Wong, T. Y., Ikram, M. K., Van Der Lee, S. J., Amin, N., Chouraki, V., Destefano, A. L., Aparicio, H. J., Romero, J. R., Maillard, P., Decarli, C., Wardlaw, J. M., Hernández, M. D. C. V., Luciano, M., Liewald, D., Deary, I. J., Starr, J. M., Bastin, M. E., Muñoz Maniega, S., Slagboom, P. E., Beekman, M., Deelen, J., Uh, H., Lemmens, R., Brodaty, H., Wright, M. J., Ames, D., Boncoraglio, G. B., Hopewell, J. C., Beecham, A. H., Blanton, S. H., Wright, C. B., Sacco, R. L., Wen, W., Thalamuthu, A., Armstrong, N. J., Chong, E., Schofield, P. R., Kwok, J. B., Van Der Grond, J., Stott, D. J., Ford, I., Jukema, J. W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., Van Der Lugt, A., Wittfeld, K., Grabe, H. J., Hosten, N., Von Sarnowski, B., Völker, U., Levi, C., Jimenez-conde, J., Sharma, P., Sudlow, C. L. M., Rosand, J., Woo, D., Cole, J. W., Meschia, J. F., Slowik, A., Thijs, V., Lindgren, A., Melander, O., Grewal, R. P., Rundek, T., Rexrode, K., Rothwell, P. M., Arnett, D. K., Jern, C., Johnson, J. A., Benavente, O. R., Wasssertheil-smoller, S., Lee, J., Wong, Q., Mitchell, B. D., Rich, S. S., Mcardle, P. F., Geerlings, M. I., Van Der Graaf, Y., De Bakker, P. I. W., Asselbergs, F. W., Srikanth, V., Thomson, R., Mcwhirter, R., Moran, C., Callisaya, M., Phan, T., Rutten-jacobs, L. C. A., Bevan, S., Tzourio, C., Mather, K. A., Sachdev, P. S., Van Duijn, C. M., Worrall, B. B., Dichgans, M., Kittner, S. J., Markus, H. S., Ikram, M. A., Fornage, M., Launer, L. J., Seshadri, S., Longstreth, W. T. & Debette, S., 2019, In: Neurology.

    Research output: Contribution to journalArticlepeer-review

  117. 2018
  118. Polygenic risk score for schizophrenia and structural brain connectivity in older age: A longitudinal connectome and tractography study

    Alloza, C., Cox, S. R., Blesa Cábez, M., Redmond, P., Whalley, H. C., Ritchie, S. J., Muñoz Maniega, S., del C Valdés Hernández, M., Tucker-Drob, E. M., Lawrie, S. M., Wardlaw, J. M., Deary, I. J. & Bastin, M. E., 31 Dec 2018, In: NeuroImage. 183, p. 884-896 13 p.

    Research output: Contribution to journalArticlepeer-review

  119. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

    Franceschini, N., Giambartolomei, C., De Vries, P. S., Finan, C., Bis, J. C., Huntley, R. P., Lovering, R. C., Tajuddin, S. M., Winkler, T. W., Graff, M., Kavousi, M., Dale, C., Smith, A. V., Hofer, E., Van Leeuwen, E. M., Nolte, I. M., Lu, L., Scholz, M., Sargurupremraj, M., Pitkänen, N. & 137 others, Franzén, O., Joshi, P. K., Noordam, R., Marioni, R. E., Hwang, S., Musani, S. K., Schminke, U., Palmas, W., Isaacs, A., Correa, A., Zonderman, A. B., Hofman, A., Teumer, A., Cox, A. J., Uitterlinden, A. G., Wong, A., Smit, A. J., Newman, A. B., Britton, A., Ruusalepp, A., Sennblad, B., Hedblad, B., Pasaniuc, B., Penninx, B. W., Langefeld, C. D., Wassel, C. L., Tzourio, C., Fava, C., Baldassarre, D., O’leary, D. H., Teupser, D., Kuh, D., Tremoli, E., Mannarino, E., Grossi, E., Boerwinkle, E., Schadt, E. E., Ingelsson, E., Veglia, F., Rivadeneira, F., Beutner, F., Chauhan, G., Heiss, G., Snieder, H., Campbell, H., Völzke, H., Markus, H. S., Deary, I. J., Jukema, J. W., De Graaf, J., Price, J., Pott, J., Hopewell, J. C., Liang, J., Thiery, J., Engmann, J., Gertow, K., Rice, K., Taylor, K. D., Dhana, K., Kiemeney, L. A. L. M., Lind, L., Raffield, L. M., Launer, L. J., Holdt, L. M., Dörr, M., Dichgans, M., Traylor, M., Sitzer, M., Kumari, M., Kivimaki, M., Nalls, M. A., Melander, O., Raitakari, O., Franco, O. H., Rueda-ochoa, O. L., Roussos, P., Whincup, P. H., Amouyel, P., Giral, P., Anugu, P., Wong, Q., Malik, R., Rauramaa, R., Burkhardt, R., Hardy, R., Schmidt, R., De Mutsert, R., Morris, R. W., Strawbridge, R. J., Wannamethee, S. G., Hägg, S., Shah, S., Mclachlan, S., Trompet, S., Seshadri, S., Kurl, S., Heckbert, S. R., Ring, S., Harris, T. B., Lehtimäki, T., Galesloot, T. E., Shah, T., De Faire, U., Plagnol, V., Rosamond, W. D., Post, W., Zhu, X., Zhang, X., Guo, X., Saba, Y., Dehghan, A., Seldenrijk, A., Morrison, A. C., Hamsten, A., Psaty, B. M., Van Duijn, C. M., Lawlor, D. A., Mook-kanamori, D. O., Bowden, D. W., Schmidt, H., Wilson, J. G., Rotter, J. I., Wardlaw, J. M., Deanfield, J., Halcox, J., Lyytikäinen, L., Loeffler, M., Evans, M. K., Debette, S., Humphries, S. E., Völker, U., Gudnason, V., Hingorani, A. D., Björkegren, J. L. M., Casas, J. P. & O’donnell, C. J., 3 Dec 2018, In: Nature Communications. 9, 1, 5141.

    Research output: Contribution to journalArticlepeer-review

  120. Baseline characteristics of the 1149 patients recruited into the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) randomized controlled trial

    Bath, P. M., Scutt, P., Appleton, J. P., Dixon, M., Woodhouse, L. J., Wardlaw, J. M. & Sprigg, N., 26 Nov 2018, In: International Journal of Stroke. p. 1747493018816451

    Research output: Contribution to journalArticlepeer-review

  121. Central masked adjudication of stroke diagnosis at trial entry offered no advantage over diagnosis by local clinicians: Secondary analysis and simulation

    Godolphin, P. J., Hepburn, T., Sprigg, N., Walker, L., Berge, E., Collins, R., Gommans, J., Ntaios, G., Pocock, S., Prasad, K., Wardlaw, J. M., Bath, P. M. & Montgomery, A. A., 10 Nov 2018, In: Contemporary clinical trials communications. 12, p. 176-181

    Research output: Contribution to journalArticlepeer-review

  122. Secondary prevention of Alzheimer's dementia: neuroimaging contributions

    Ten Kate, M., Ingala, S., Schwarz, A. J., Fox, N. C., Chételat, G., van Berckel, B. N. M., Ewers, M., Foley, C., Gispert, J. D., Hill, D., Irizarry, M. C., Lammertsma, A. A., Molinuevo, J. L., Ritchie, C., Scheltens, P., Schmidt, M. E., Visser, P. J., Waldman, A., Wardlaw, J., Haller, S. & 1 others, Barkhof, F., 30 Oct 2018, In: Alzheimer's research & therapy. 10, 1, p. 112

    Research output: Contribution to journalReview articlepeer-review

  123. Action Plan for Stroke in Europe 2018–2030

    Norrving, B., Barrick, J., Davalos, A., Dichgans, M., Cordonnier, C., Guekht, A., Kutluk, K., Mikulik, R., Wardlaw, J., Richard, E., Nabavi, D., Molina, C., Bath, P. M., Stibrant Sunnerhagen, K., Rudd, A., Drummond, A., Planas, A. & Caso, V., 29 Oct 2018, In: European Stroke Journal. p. 239698731880871

    Research output: Contribution to journalArticlepeer-review

  124. Effect of IV alteplase on the ischemic brain lesion at 24-48 hours after ischemic stroke

    Mair, G., von Kummer, R., Morris, Z., von Heijne, A., Bradey, N., Cala, L., Peeters, A., Farrall, A., Adami, A., Potter, G., Sandercock, P., Lindley, R. I., Wardlaw, J. & IST-3 Collaborative Group, 26 Oct 2018, In: Neurology. 91, 22, p. e2067-e2077

    Research output: Contribution to journalArticlepeer-review

  125. Percutaneous vascular interventions versus intravenous thrombolytic treatment for acute ischaemic stroke

    Lindekleiv, H., Berge, E., Bruins Slot, K. M. & Wardlaw, J. M., 26 Oct 2018, In: The Cochrane Library.

    Research output: Contribution to journalReview articlepeer-review

  126. The association between carotid atheroma and cerebral cortex structure at age 73

    Alhusaini, S., Karama, S., Nguyen, T-V., Thiel, A., Bernhardt, B., Cox, S., Corley, J., Taylor, A., Evans, A. C., Starr, J., Bastin, M., Wardlaw, J., Deary, I. & Ducharme, S., Oct 2018, In: Annals of Neurology. 84, 4, p. 576-587

    Research output: Contribution to journalArticlepeer-review

  127. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

    Vojinovic, D., Adams, H. H., Jian, X., Yang, Q., Smith, A. V., Bis, J. C., Teumer, A., Scholz, M., Armstrong, N. J., Hofer, E., Saba, Y., Luciano, M., Bernard, M., Trompet, S., Yang, J., Gillespie, N. A., Van Der Lee, S. J., Neumann, A., Ahmad, S., Andreassen, O. A. & 71 others, Ames, D., Amin, N., Arfanakis, K., Bastin, M. E., Becker, D. M., Beiser, A. S., Beyer, F., Brodaty, H., Bryan, R. N., Bülow, R., Dale, A. M., De Jager, P. L., Deary, I. J., Decarli, C., Fleischman, D. A., Gottesman, R. F., Van Der Grond, J., Gudnason, V., Harris, T. B., Homuth, G., Knopman, D. S., Kwok, J. B., Lewis, C. E., Li, S., Loeffler, M., Lopez, O. L., Maillard, P., El Marroun, H., Mather, K. A., Mosley, T. H., Muetzel, R. L., Nauck, M., Nyquist, P. A., Panizzon, M. S., Pausova, Z., Psaty, B. M., Rice, K., Rotter, J. I., Royle, N., Satizabal, C. L., Schmidt, R., Schofield, P. R., Schreiner, P. J., Sidney, S., Stott, D. J., Thalamuthu, A., Uitterlinden, A. G., Valdés Hernández, M. C., Vernooij, M. W., Wen, W., White, T., Witte, A. V., Wittfeld, K., Wright, M. J., Yanek, L. R., Tiemeier, H., Kremen, W. S., Bennett, D. A., Jukema, J. W., Paus, T., Wardlaw, J. M., Schmidt, H., Sachdev, P. S., Villringer, A., Grabe, H. J., Longstreth, W. T., Van Duijn, C. M., Launer, L. J., Seshadri, S., Ikram, M. A. & Fornage, M., 26 Sep 2018, In: Nature Communications. 9, 1, 3945.

    Research output: Contribution to journalArticlepeer-review

  128. Reproducibility of Transcranial Doppler ultrasound in the middle cerebral artery

    Kaczynski, J., Home, R., Shields, K., Walters, M., Whiteley, W., Wardlaw, J. & Newby, D. E., 11 Sep 2018, In: Cardiovascular ultrasound. 16, 1, p. 15

    Research output: Contribution to journalArticlepeer-review

  129. Considerations on accuracy, pattern and possible underlying factors of brain microbleeds progression on older adults with absence or mild presence of vascular pathology

    Alzheimer’s Disease Neuroimaging Initiative, 1 Sep 2018, In: Journal of International Medical Research. 21 p.

    Research output: Contribution to journalArticlepeer-review

  130. Longitudinal serum S100β and brain ageing in the Lothian Birth Cohort 1936

    Cox, S., Allerhand, M., Ritchie, S. J., Muñoz Maniega, S., Valdes Hernandez, M., Harris, S., Dickie, D. A., Anblagan, D., Aribisala, B., Morris, Z., Sherwood, R., Abbott, N. J., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Sep 2018, In: Neurobiology of Aging. 69, p. 274-282

    Research output: Contribution to journalArticlepeer-review

  131. Machine learning of neuroimaging for assisted diagnosis of cognitive impairment and dementia: A systematic review

    Pellegrini, E., Ballerini, L., Hernandez, M. D. C. V., Chappell, F. M., González-castro, V., Anblagan, D., Danso, S., Maniega, S. M., Job, D., Pernet, C., Mair, G., Macgillivray, T., Trucco, E. & Wardlaw, J., 11 Aug 2018, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalReview articlepeer-review

  132. Impact of detecting potentially serious incidental findings during multi-modal imaging: [version 3; peer review: 2 approved, 1 approved with reservations]

    Gibson, L. M., Littlejohns, T. J., Adamska, L., Garratt, S., Doherty, N., Wardlaw, J. M., Maskell, G., Parker, M., Brownsword, R., Matthews, P. M., Collins, R., Allen, N. E., Sellors, J. & Sudlow, C., 2 Aug 2018, In: Wellcome Open Research . 2, p. 114

    Research output: Contribution to journalArticlepeer-review

  133. Widespread associations between trait conscientiousness and thickness of brain cortical regions

    Lewis, G. J., Dickie, D. A., Cox, S. R., Karama, S., Evans, A. C., Starr, J. M., Bastin, M. E., Wardlaw, J. M. & Deary, I. J., 1 Aug 2018, In: NeuroImage. 176, p. 22-28

    Research output: Contribution to journalArticlepeer-review

  134. Exome chip analysis identifies low-frequency and rare variants in MRPL38 for white matter hyperintensities on brain MRI

    Jian, X., Satizabal, C. L., Smith, A. V., Wittfield, K., Bis, J. C., Smith, J., Hsu, F-C., Nho, K., Hofer, E., Hagenaars, S., Nyquist, P. A., Mishra, A., Adams, H. H. H., Li, S., Teumer, A., Zhao, W., Freedman, B. I., Saba, Y., Yanek, L. R., Chauhan, G. & 58 others, Van Buchem, M. A., Cushman, M., Royle, N., Bryan, R. N., Niessen, W. J., Windham, B. G., DeStefano, A. L., Habes, M., Heckbert, S. R., Palmer, N. D., Lewis, C. E., Eiriksdottir, G., Maillard, P., Mathias, R. A., Homuth, G., Valdes Hernandez, M., Divers, J., Beiser, A. S., Langner, S., Rice, K. M., Bastin, M., Yang, Q., Maldjan, J. A., Starr, J., Sidney, S. S., Risacher, S. L., Uitterlinden, A. G., Gudnason, V., Nauck, M., Rotter, J. I., Schreiner, P. J., Boerwinkle, E., van Duijn, C., Mazoyer, B., von Sarnowski, B., Gottesman, R. F., Levy, D., Sigurdsson, S., Vernooij, M. W., Turner, S. T., Schmidt, R., Wardlaw, J., Psaty, B. M., Mosley, T. H., DeCarli, C., Saykin, A. J., Bowden, D. W., Becker, D. M., Deary, I., Schmidt, H., Kardia, S. L. R., Ikram, M. A., Debette, S., Grabe, H. J., Longstreth, W. T., Seshadri, S., Launer, L. J. & Fornage, M., 12 Jul 2018, In: Stroke. 49, 8, p. 1812-1819

    Research output: Contribution to journalArticlepeer-review

  135. The Glymphatic System and Waste Clearance with Brain Aging: A Review

    Benveniste, H., Liu, X., Koundal, S., Sanggaard, S., Lee, H. & Wardlaw, J., 11 Jul 2018, In: Gerontology. p. 1-14 14 p.

    Research output: Contribution to journalReview articlepeer-review

  136. Reversal of endothelial dysfunction reduces white matter vulnerability in cerebral small vessel disease in rats

    Rajani, R. M., Quick, S., Ruigrok, S. R., Graham, D., Harris, S. E., Verhaaren, B. F. J., Fornage, M., Seshadri, S., Atanur, S. S., Dominiczak, A. F., Smith, C., Wardlaw, J. M. & Williams, A., 4 Jul 2018, In: Science Translational Medicine. 10, 448, 12 p., eaam9507.

    Research output: Contribution to journalArticlepeer-review

  137. The relation between total cerebral small vessel disease burden and gait impairment in patients with minor stroke

    Loos, C. M. J., McHutchison, C., Cvoro, V., Makin, S., Staals, J., Chappell, F., Dennis, M., van Oostenbrugge, R. J. & Wardlaw, J., 1 Jul 2018, In: International Journal of Stroke. 13, 5, p. 518-524

    Research output: Contribution to journalArticlepeer-review

  138. William M. Feinberg Award for Excellence in Clinical Stroke: Small Vessel Disease; a Big Problem, But Fixable

    Wardlaw, J. M., 12 Jun 2018, In: Stroke. 49, 7, p. 1770-1775

    Research output: Contribution to journalArticlepeer-review

  139. Neurological Disease in Lupus: Toward a Personalized Medicine Approach

    Mcglasson, S., Wiseman, S., Wardlaw, J., Dhaun, N. & Hunt, D. P. J., 6 Jun 2018, In: Frontiers in Immunology. 9

    Research output: Contribution to journalReview articlepeer-review

  140. A large margin algorithm for automated segmentation of white matter hyperintensity

    Qin, C., Guerrero, R., Bowles, C., Chen, L., Dickie, D. A., Valdes-Hernandez, M. D. C., Wardlaw, J. & Rueckert, D., 31 May 2018, In: Pattern Recognition. 77, p. 150-159 10 p.

    Research output: Contribution to journalArticlepeer-review

  141. Brain age predicts mortality

    Cole, J. H., Ritchie, S. J., Bastin, M. E., Valdés Hernández, M. C., Muñoz Maniega, S., Royle, N., Corley, J., Pattie, A., Harris, S. E., Zhang, Q., Wray, N. R., Redmond, P., Marioni, R. E., Starr, J. M., Cox, S. R., Wardlaw, J. M., Sharp, D. J. & Deary, I. J., 31 May 2018, In: Molecular Psychiatry. 23, p. 1385-1392 8 p.

    Research output: Contribution to journalArticlepeer-review

  142. Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium

    Kong, X-Z., Mathias, S. R., Guadalupe, T., Glahn, D. C., Franke, B., Crivello, F., Tzourio-Mazoyer, N., Fisher, S. E., Thompson, P. M., Francks, C., ENIGMA Laterality Working Group, Valdes Hernandez, M., Wardlaw, J., Harris, M. & Luciano, M., 29 May 2018, In: Proceedings of the National Academy of Sciences. 115, 22, p. E5154-E5163

    Research output: Contribution to journalArticlepeer-review

  143. Fourth European stroke science workshop

    Debette, S., Strbian, D., Wardlaw, J., Van Der Worp, H., Rinkel, G., Caso, V., Dichgans, M., Tournier-lasserve, E., Grefkes, C., Kelly, P., Muir, K., Berge, E., Trégouët, D., Roffe, C., Brainin, M., Beck, J., Steiner, T., De Lau, L., Jouvent, E., Veltkamp, R. & 26 others, Baron, J., Nedeltchev, K., Bath, P., Quinn, T., Richard, E., Ziemann, U., Liesz, A., Ntaios, G., Iadecola, C., Lees, K., Christensen, H. K., Van Veluw, S., Endres, M., Anderson, C., Molina, C., Düring, M., Dufouil, C., Ostergaard, L., Samani, N., Fischer, U., De Leeuw, F., Norrving, B., Biessels, G., Cordonnier, C., Mas, J. & Mattle, H., 24 May 2018, In: European Stroke Journal. 3, 3, p. 206-219

    Research output: Contribution to journalComment/debatepeer-review

  144. Rapid automated quantification of cerebral leukoaraiosis on CT images: A Multicenter Validation Study

    Chen, L., Carlton Jones, A. L., Mair, G., Patel, R., Gontsarova, A., Ganesalingam, J., Math, N., Dawson, A., Aweid, B., Cohen, D., Mehta, A., Wardlaw, J., Rueckert, D., Bentley, P. & IST-3 Collaborative Group, 15 May 2018, In: Radiology. 288, 2, p. 573–581 9 p.

    Research output: Contribution to journalArticlepeer-review

  145. Longitudinal MRI dynamics of recent small subcortical infarcts and possible predictors

    Pinter, D., Gattringer, T., Enzinger, C., Seifert-Held, T., Kneihsl, M., Fandler, S., Pichler, A., Barro, C., Eppinger, S., Pirpamer, L., Bachmaier, G., Ropele, S., Wardlaw, J., Kuhle, J., Khalil, M. & Fazekas, F., 8 May 2018, In: Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalArticlepeer-review

  146. Cognitive function, disease burden and the structural connectome in systemic lupus erythematosus

    Wiseman, S., Bastin, M., Amft, E., Belch, J. F. F., Ralston, S. & Wardlaw, J., 3 May 2018, In: Lupus.

    Research output: Contribution to journalArticlepeer-review

  147. Protocol for a prospective collaborative systematic review and meta-analysis of individual patient data from randomized controlled trials of vasoactive drugs in acute stroke: The Blood pressure in Acute Stroke Collaboration, stage-3

    Sandset, E. C., Sanossian, N., Woodhouse, L. J., Anderson, C., Berge, E., Lees, K. R., Potter, J. F., Robinson, T. G., Sprigg, N., Wardlaw, J. M., Bath, P. M. & Blood pressure in Acute Stroke Collaboration Investigators, 3 May 2018, In: International Journal of Stroke. p. 1747493018772733

    Research output: Contribution to journalArticlepeer-review

  148. Understanding the role of the perivascular space in cerebral small vessel disease

    Brown, R., Benveniste, H., Black, S. E., Charpak, S., Dichgans, M., Joutel, A., Nedergaard, M., Smith, K. J., Zlokovic, B. V. & Wardlaw, J. M., 2 May 2018, In: Cardiovascular Research.

    Research output: Contribution to journalArticlepeer-review

  149. 'Small vessels, dementia and chronic diseases -molecular mechanisms and pathophysiology' Workshop proceedings

    Horsburgh, K., Wardlaw, J., Van Agtmael, T., Allan, S., Ashford, M., Bath, P. M., Brown, R., Berwick, J., Cader, M. Z., Carare, R. O., Davies, J. B., Duncombe, J., Farr, T. D., Fowler, J., Goense, J., Granata, A., Hall, C., Hainsworth, A., Harvey, A., Hawkes, C. & 26 others, Joutel, A., Kalaria, R. N., Kehoe, P. G., Lawrence, C. B., Lockhart, A., Love, S., MacLeod, M., Macrae, M., Markus, H. S., McCabe, C., McColl, B., Meakin, P. J., Miller, A. A., Nedergaard, M., O'Sullivan, M., Quinn, T., Rajani, R., Saksida, L. M., Smith, C., Smith, K. J., Touyz, R., Trueman, R., Wang, T., Williams, A., Williams, S. & Work, L. M., 30 Apr 2018, In: Clinical science. 132, 8, p. 851-868

    Research output: Contribution to journalReview articlepeer-review

  150. The Brain Health Index: Towards a combined measure of neurovascular and neurodegenerative structural brain injury

    Dickie, D. A., Valdes Hernandez, M., Makin, S., Staals, J., Wiseman, S., Bastin, M. & Wardlaw, J., 19 Apr 2018, In: International Journal of Stroke.

    Research output: Contribution to journalArticlepeer-review

  151. Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease

    Bailey, E. L., Mcbride, M. W., Mcclure, J. D., Beattie, W., Graham, D., Dominiczak, A. F., Smith, C. & Wardlaw, J., 9 Apr 2018, In: Clinical science.

    Research output: Contribution to journalArticlepeer-review

  152. Direct Estimation of Pharmacokinetic Parameters from DCE-MRI using Deep CNN with Forward Physical Model Loss

    Ulas, C., Tetteh, G., Thrippleton, M. J., Armitage, P. A., Makin, S. D., Wardlaw, J. M., Davies, M. E. & Menze, B. H., 8 Apr 2018.

    Research output: Contribution to conferencePaperpeer-review

  153. Towards standardization of quantitative retinal vascular parameters: Comparison of SIVA and VAMPIRE measurements in the Lothian Birth Cohort 1936

    McGrory, S., Taylor, A., Pellegrini, E., Ballerini, L., Kirin, M., Doubal, F., Wardlaw, J., Doney, A. S. F., Dhillon, B., Starr, J., Trucco, E., Deary, I. & MacGillivray, T., 23 Mar 2018, In: Translational Vision Science and Technology. 7, 12

    Research output: Contribution to journalArticlepeer-review

  154. Visual rating scales of white matter hyperintensities and atrophy: comparison of computed tomography and magnetic resonance imaging

    Ferguson, K., Cvoro, V., Maclullich, A., Shenkin, S., Sandercock, P., Sakka, E. & Wardlaw, J., 23 Mar 2018, In: Journal of Stroke and Cerebrovascular Diseases.

    Research output: Contribution to journalArticlepeer-review

  155. Long-term morphological changes of symptomatic lacunar infarcts and surrounding white matter on structural MRI

    Loos, C. M. J., Makin, S., Staals, J., Dennis, M., van Oostenbrugge, R. J. & Wardlaw, J., 22 Mar 2018, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  156. The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage with cerebral amyloid angiopathy: model development and diagnostic test accuracy study

    Rodrigues, M. A., Samarasekera, N., Lerpiniere, C., Humphreys, C., McCarron, M. O., White, P. M., Nicoll, J. A. R., Sudlow, C. L. M., Cordonnier, C., Wardlaw, J., Smith, C. & Salman, R. A-S., 1 Mar 2018, In: Lancet Neurology. 17, 3, p. 232-240 9 p.

    Research output: Contribution to journalArticlepeer-review

  157. Cognitive abilities, brain white matter hyperintensity volume and structural network connectivity in older age

    Wiseman, S. J., Booth, T., Ritchie, S. J., Cox, S. R., Muñoz Maniega, S., Valdes Hernandez, M. D. C., Dickie, D. A., Royle, N. A., Starr, J. M., Deary, I. J., Wardlaw, J. M. & Bastin, M. E., 28 Feb 2018, In: Human Brain Mapping. 39, 2, p. 622-632 11 p.

    Research output: Contribution to journalArticlepeer-review

  158. Cohort Profile: Stratifying Resilience and Depression Longitudinally (STRADL): A questionnaire follow-up of Generation Scotland: Scottish Family Health Study (GS:SFHS)

    Navrady, L., Wolters, M., MacIntyre, D., Clarke, T-K., Campbell, A., Murray, A., Evans, K., Seckl, J., Haley, C., Milburn, K., Wardlaw, J., Porteous, D., Deary, I. & McIntosh, A., 1 Feb 2018, In: International Journal of Epidemiology. 47, 1, p. 13-14g

    Research output: Contribution to journalArticlepeer-review

  159. Perivascular Spaces Segmentation in Brain MRI Using Optimal 3D Filtering

    Ballerini, L., Lovreglio, R., Valdes Hernandez, M., Ramirez, J., MacIntosh, B., Black, S. & Wardlaw, J., 1 Feb 2018, In: Scientific Reports. 8, 2132.

    Research output: Contribution to journalArticlepeer-review

  160. Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’

    Scutt, P., Appleton, J. P., Dixon, M. S., Woodhouse, L. J., Sprigg, N., Wardlaw, J. M., Montgomery, A. A., Pocock, S. J. & Bath, P. M., 1 Feb 2018, In: European Stroke Journal. p. 239698731875669

    Research output: Contribution to journalArticlepeer-review

  161. Brain structural differences between 73- and 92-year olds matched for childhood intelligence, social background, and intracranial volume

    Ritchie, S. J., Dickie, D. A., Cox, S., Valdes Hernandez, M., Sibbett, R., Pattie, A., Anblagan, D., Redmond, P., Royle, N., Corley, J., Muñoz Maniega, S., Taylor, A., Karama, S., Booth, T., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Feb 2018, In: Neurobiology of Aging. 62, p. 146-158

    Research output: Contribution to journalArticlepeer-review

  162. Brain cortical characteristics of lifetime cognitive ageing

    Cox, S. R., Bastin, M. E., Ritchie, S. J., Dickie, D. A., Liewald, D. C., Muñoz Maniega, S., Redmond, P., Royle, N. A., Pattie, A., Valdes Hernandez, M., Corley, J., Aribisala, B. S., McIntosh, A. M., Wardlaw, J. M. & Deary, I. J., 31 Jan 2018, In: Brain Structure and Function. 223, 1, p. 509–518 10 p.

    Research output: Contribution to journalArticlepeer-review

  163. Predictors of gait speed and its change over three years in community-dwelling older people

    Pinter, D., Ritchie, S. J., Gattringer, T., Bastin, M., Valdes Hernandez, M., Corley, J., Muñoz Maniega, S., Pattie, A., Dickie, D. A., Gow, A., Starr, J., Deary, I., Enzinger, C., Fazekas, F. & Wardlaw, J., 20 Jan 2018, In: Aging.

    Research output: Contribution to journalArticlepeer-review

  164. The impact of early life intelligence quotient on post stroke cognitive impairment

    Makin, S., Doubal, F., Shuler, K., Chappell, F., Staals, J., Dennis, M. & Wardlaw, J., 8 Jan 2018, In: European Stroke Journal.

    Research output: Contribution to journalArticlepeer-review

  165. Coupled changes in hippocampal structure and cognitive ability in later life

    Anblagan, D., Valdes Hernandez, M., Ritchie, S. J., Aribisala, B., Royle, N., Hamilton, I., Cox, S., Gow, A., Pattie, A., Corley, J., Starr, J., Muñoz Maniega, S., Bastin, M., Deary, I. & Wardlaw, J., 4 Jan 2018, In: Brain and Behavior.

    Research output: Contribution to journalArticlepeer-review

  166. White matter hyperintensity and stroke lesion segmentation and differentiation using convolutional neural networks

    Guerrero, R., Qin, C., Oktay, O., Bowles, C., Chen, L., Joules, R., Wolz, R., Valdes-Hernandez, M. C., Dickie, D. A., Wardlaw, J. & Rueckert, D., 2018, In: NeuroImage: Clinical. 17, p. 918-934 16 p.

    Research output: Contribution to journalArticlepeer-review

  167. 2017
  168. Variance components associated with long-echo-time MR spectroscopic imaging in human brain at 1.5T and 3T

    Thrippleton, M., Parikh, J., Semple, S., Harris, B., Andrews, P., Wardlaw, J. & Marshall, I., 29 Dec 2017, In: PLoS ONE.

    Research output: Contribution to journalArticlepeer-review

  169. Reference Tracts and Generative Models for Brain White Matter Tractography †

    Muñoz Maniega, S., Bastin, M., Deary, I., Wardlaw, J. & Clayden, J., 28 Dec 2017, In: Journal of Imaging . 4, 1, p. 8

    Research output: Contribution to journalArticlepeer-review

  170. Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data

    Campbell, B. C. V., Van Zwam, W. H., Goyal, M., Menon, B. K., Dippel, D. W. J., Demchuk, A. M., Bracard, S., White, P., Dávalos, A., Majoie, C. B. L. M., Van Der Lugt, A., Ford, G. A., De La Ossa, N. P., Kelly, M., Bourcier, R., Donnan, G. A., Roos, Y. B. W. E. M., Bang, O. Y., Nogueira, R. G., Devlin, T. G. & 1,356 others, Van Den Berg, L. A., Clarençon, F., Burns, P., Carpenter, J., Berkhemer, O. A., Yavagal, D. R., Pereira, V. M., Ducrocq, X., Dixit, A., Quesada, H., Epstein, J., Davis, S. M., Jansen, O., Rubiera, M., Urra, X., Micard, E., Lingsma, H. F., Naggara, O., Brown, S., Guillemin, F., Muir, K. W., Van Oostenbrugge, R. J., Saver, J. L., Jovin, T. G., Hill, M. D., Mitchell, P. J., Berkhemer, O. A., Fransen, P. S., Beumer, D., Van Den Berg, L. A., Lingsma, H. F., Yoo, A. J., Schonewille, W. J., Vos, J. A., Nederkoorn, P. J., Wermer, M. J., Van Walderveen, M. A., Staals, J., Hofmeijer, J., Van Oostayen, J. A., Lycklama À Nijeholt, G. J., Boiten, J., Brouwer, P. A., Emmer, B. J., De Bruijn, S. F., Van Dijk, L. C., Kappelle, J., Lo, R. H., Van Dijk, E. J., De Vries, J., De Kort, P. L. M., Van Rooij, W. J. J., Van Den Berg, J. S. P., Van Hasselt, B. A. A. M., Aerden, L. A. M., Dallinga, R. J., Visser, M. C., Bot, J. C. J., Vroomen, P. C., Eshghi, O., Schreuder, T. H. C. M. L., Heijboer, R. J. J., Keizer, K., Tielbeek, A. V., Den Hertog, H. M., Gerrits, D. G., Van Den Berg-vos, R. M., Karas, G. B., Steyerberg, E. W., Flach, Z., Marquering, H. A., Sprengers, M. E. S., Jenniskens, S. F. M., Beenen, L. F. M., Van Den Berg, R., Koudstaal, P. J., Van Zwam, W. H., Roos, Y. B. W. E. M., Van Der Lugt, A., Van Oostenbrugge, R. J., Majoie, C. B. L. M., Dippel, D. W. J., Brown, M. M., Liebig, T., Stijnen, T., Andersson, T., Mattle, H., Wahlgren, N., Van Der Heijden, E., Ghannouti, N., Fleitour, N., Hooijenga, I., Puppels, C., Pellikaan, W., Geerling, A., Lindl-velema, A., Van Vemde, G., De Ridder, A., Greebe, P., De Bont-stikkelbroeck, J., De Meris, J., Janssen, K., Struijk, W., Licher, S., Boodt, N., Ros, A., Venema, E., Slokkers, I., Ganpat, R., Mulder, M., Saiedie, N., Heshmatollah, A., Schipperen, S., Vinken, S., Van Boxtel, T., Koets, J., Boers, M., Santos, E., Borst, J., Jansen, I., Kappelhof, M., Lucas, M., Geuskens, R., Barros, R. 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M., Clifton, A., Freeman, J., Ford, I., Markus, H., Wardlaw, J., Lees, K. R., Molyneux, A., Robinson, T., Lewis, S., Norrie, J., Robertson, F., Perry, R., Dixit, A., Cloud, G., Clifton, A., Madigan, J., Roffe, C., Nayak, S., Lobotesis, K., Smith, C., Herwadkar, A., Kandasamy, N., Goddard, T., Bamford, J., Subramanian, G., Lenthall, R., Littleton, E., Lamin, S., Storey, K., Ghatala, R., Banaras, A., Aeron-thomas, J., Hazel, B., Maguire, H., Veraque, E., Harrison, L., Keshvara, R. & Cunningham, J., 16 Dec 2017, In: Lancet Neurology. 17, 1, p. 47-53

    Research output: Contribution to journalArticlepeer-review

  171. Intracranial pulsatility in patients with cerebral small vessel disease: a systematic review

    Shi, Y., Thrippleton, M., Marshall, I. & Wardlaw, J., 11 Dec 2017, In: Clinical science.

    Research output: Contribution to journalArticlepeer-review

  172. Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: Individual-patient-data meta-analysis of randomized trials

    Hacke, W., Lyden, P., Emberson, J., Baigent, C., Blackwell, L., Albers, G. W., Bluhmki, E., Brott, T. G., Cohen, G. R., Davis, S. M., Donnan, G. A., Grotta, J. C., Howard, G., Kaste, M., Koga, M., von Kummer, R., Lansberg, M. G., Lindley, R. I., Olivot, J. M., Parsons, M. & 8 others, Sandercock, P., Toni, D., Toyoda, K., Wahlgren, N., Wardlaw, J., Whiteley, W., del Zoppo, G. J. & Lees, K. R., 24 Nov 2017, In: International Journal of Stroke.

    Research output: Contribution to journalArticlepeer-review

  173. Relationship between race and outcome in Asian, Black, and Caucasian patients with spontaneous intracerebral hemorrhage: Data from the Virtual International Stroke Trials Archive and Efficacy of Nitric Oxide in Stroke trial

    Krishnan, K., Beishon, L., Berge, E., Christensen, H., Dineen, R. A., Ozturk, S., Sprigg, N., Wardlaw, J. M. & Bath, P. M., 22 Nov 2017, In: International Journal of Stroke. p. 174749301774446

    Research output: Contribution to journalArticlepeer-review

  174. Dietary iodine exposure and brain structures and cognition in older people. Exploratory analysis in the Lothian Birth Cohort 1936

    Valdes Hernandez, M., Kyle, J., Allan, J., Allerhand, M., Clark, H., Muñoz Maniega, S., Royle, N., Gow, A., Pattie, A., Corley, J., Bastin, M., Starr, J., Wardlaw, J., Deary, I. & Combet, E., Nov 2017, In: Journal of Nutrition, Health and Aging. 21, 9, p. 971-979

    Research output: Contribution to journalArticlepeer-review

  175. Risk and protective factors for structural brain ageing in the eighth decade of life

    Ritchie, S. J., Tucker-Drob, E. M., Cox, S., Dickie, D. A., Valdes Hernandez, M., Corley, J., Royle, N., Redmond, P., Muñoz Maniega, S., Pattie, A., Aribisala, B., Taylor, A., Clarke, T-K., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Nov 2017, In: Brain Structure and Function. 222, 8, p. 1-14 14 p.

    Research output: Contribution to journalArticlepeer-review

  176. Variation in a range of mTOR-related genes associates with intracranial volume and intellectual disability

    ENIGMA Consortium, 20 Oct 2017, In: Nature Communications.

    Research output: Contribution to journalArticlepeer-review

  177. Optimizing the Definitions of Stroke, TIA and Infarction for Research and Application in Clinical Practice

    Abbott, A. L., Silvestrini, M., Topakian, R., Golledge, J., Brunser, A., de Borst, G. J., Harbaugh, R. E., Doubal, F., Rundek, T., Thapar, A., Davies, A. H., Kam, A. & Wardlaw, J., 18 Oct 2017, In: Frontiers in Neurology.

    Research output: Contribution to journalArticlepeer-review

  178. Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis

    Duncombe, J., Lennen, R. J., Jansen, M. A., Marshall, I., Wardlaw, J. M. & Horsburgh, K., Oct 2017, In: Neuropathology and Applied Neurobiology. 43, 6

    Research output: Contribution to journalArticlepeer-review

  179. Processing speed and the relationship between Trail Making Test-B performance, cortical thinning and white matter microstructure in older adults

    MacPherson, S. E., Cox, S. R., Dickie, D. A., Karama, S., Starr, J. M., Evans, A. C., Bastin, M. E., Wardlaw, J. M. & Deary, I. J., Oct 2017, In: Cortex. 95, p. 92-103

    Research output: Contribution to journalArticlepeer-review

  180. Cerebrovascular reactivity measurement in cerebral small vessel disease: rationale and reproducibility of a protocol for MRI acquisition and image processing

    Thrippleton, M., Shi, Y., Blair, G., Hamilton, I., Waiter, G. D., Schwarzbauer, C., Pernet, C. R., Andrews, P., Marshall, I., Doubal, F. & Wardlaw, J., 21 Sep 2017, In: International Journal of Stroke.

    Research output: Contribution to journalArticlepeer-review

  181. Retinal Biomarker Discovery for Dementia in an Elderly Diabetic Population

    VAMPIRE project, Vascular Assessment and Measurement Platform for Images of the REtina, 9 Sep 2017, International Workshop on Ophthalmic Medical Image Analysis. Springer, p. 150-158 (LNCS; vol. 10554).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  182. Small vessel disease and dietary salt intake: cross sectional study and systematic review

    Makin, S., Mubki, G. F., Doubal, F., Shuler, K., Staals, J., Dennis, M. & Wardlaw, J., 8 Sep 2017, In: Journal of Stroke and Cerebrovascular Diseases.

    Research output: Contribution to journalArticlepeer-review

  183. Blood pressure variability and leukoaraiosis in acute ischemic stroke

    Dickie, D. A., Aribisala, B., Mair, G., Berge, E., Lindley, R. I., Sandercock, P., von Kummer, R., von Heijne, A., Peeters, A., Cala, L., Farrall, A., Morris, Z., Bradey, N., Potter, G., Adami, A. & Wardlaw, J., 5 Sep 2017, In: International Journal of Stroke.

    Research output: Contribution to journalArticlepeer-review

  184. White matter hyperintensity reduction and outcomes after minor stroke

    Wardlaw, J. M., Chappell, F. M., Valdés Hernández, M. D. C., Makin, S. D. J., Staals, J., Shuler, K., Thrippleton, M. J., Armitage, P. A., Muñoz Maniega, S., Heye, A. K., Sakka, E. & Dennis, M. S., 5 Sep 2017, In: Neurology. 89, 10, p. 1003-1010

    Research output: Contribution to journalArticlepeer-review

  185. Maximising the Potential of Longitudinal Cohorts for Research in Neurodegenerative Diseases: A Community Perspective

    Moody, C., Mitchell, D., Kiser, G., Aarsland, D., Berg, D., Brayne, C., Costa, A., Arfan Ikram, M., Mountain, G., Rohrer, J. D., Teunissen, C., van den Berg, L. H. & Wardlaw, J., 29 Aug 2017, In: Frontiers in Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  186. Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: Rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053)

    Appleton, J. P., Scutt, P., Dixon, M., Howard, H., Haywood, L., Havard, D., Hepburn, T., England, T., Sprigg, N., Woodhouse, L. J., Wardlaw, J. M., Montgomery, A. A., Pocock, S., Bath, P. M. & RIGHT-2 Investigators, 1 Aug 2017, In: International Journal of Stroke. p. 1747493017724627

    Research output: Contribution to journalArticlepeer-review

  187. Brain grey and white matter predictors of verbal ability traits in older age: The Lothian Birth Cohort 1936

    Hoffman, P., Cox, S. R., Dykiert, D., Muñoz Maniega, S., Valdes Hernandez, M. C., Bastin, M. E., Wardlaw, J. M. & Deary, I. J., 1 Aug 2017, In: NeuroImage. 156, p. 394-402 9 p.

    Research output: Contribution to journalArticlepeer-review

  188. Infections up to 76 days after stroke increase disability and death

    Learoyd, A. E., Woodhouse, L., Shaw, L., Sprigg, N., Bereczki, D., Berge, E., Caso, V., Christensen, H., Collins, R., Czlonkowska, A., El Etribi, A., Farr, T. D., Gommans, J., Laska, A. C., Ntaios, G., Ozturk, S., Pocock, S. J., Prasad, K., Wardlaw, J., Fone, K. & 2 others, Bath, P. M. & Trueman, R. C., 27 Jul 2017, In: Translational Stroke Research.

    Research output: Contribution to journalArticlepeer-review

  189. Application of texture analysis to study small vessel disease and blood brain barrier integrity

    Valdes Hernandez, M., Gonzalez- Castro, V., Chappell, F., Sakka, E., Makin, S., Armitage, P., Nailon, W. H. & Wardlaw, J., 19 Jul 2017, In: Frontiers in Neurology. 8, p. 327 1 p.

    Research output: Contribution to journalArticlepeer-review

  190. Detection, risk factors, and functional consequences of cerebral microinfarcts

    van Veluw, S. J., Shih, A. Y., Smith, E. E., Chen, C., Schneider, J. A., Wardlaw, J., Greenberg, S. M. & Biessels, G. J., 14 Jul 2017, In: Lancet Neurology.

    Research output: Contribution to journalArticlepeer-review

  191. Education, socioeconomic status, and intelligence in childhood and stroke risk in later life: A Meta-analysis

    McHutchison, C., Backhouse, E., Cvoro, V., Shenkin, S. & Wardlaw, J., Jul 2017, In: Epidemiology. 28, 4

    Research output: Contribution to journalArticlepeer-review

  192. Retinal microvascular network geometry and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort 1936 Study

    McGrory, S., Taylor, A., Kirin, M., Corley, J., Pattie, A., Cox, S., Dhillon, B., Wardlaw, J., Doubal, F., Starr, J., Trucco, E., MacGillivray, T. & Deary, I., Jul 2017, In: British Journal of Ophthalmology. 101, 7, p. 993-998

    Research output: Contribution to journalArticlepeer-review

  193. Small vessel disease and clinical outcomes after IV rt-PA treatment

    Arba, F., Inzitari, D., Ali, M., Warach, S. J., Luby, M., Lees, K. R., Albers, G. W., Davis, S. M., Donnan, G. A., Fisher, M., Furlan, A. J., Grotta, J. C., Hacke, W., Kang, D. W., Kidwell, C., Koroshetz, W. J., Lev, M. H., Liebeskind, D. S., Gregory Sorensen, A., Thijs, V. N. & 3 others, Thomalla, G., Wardlaw, J. M. & Wintermark, M., Jul 2017, In: Acta neurologica Scandinavica. 136, 1, p. 72-77 6 p.

    Research output: Contribution to journalArticlepeer-review

  194. Improved reference tracts for unsupervised brain white matter tractography

    Muñoz Maniega, S., Bastin, M., Deary, I., Wardlaw, J. & Clayden, J. D., 22 Jun 2017, Medical Image Understanding and Analysis: 21st Annual Conference, MIUA 2017, Edinburgh, UK, July 11–13, 2017, Proceedings. p. 425-435 (Communications in Computer and Information Science).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  195. Advanced neuroimaging of cerebral small vessel disease

    Blair, G., Valdes Hernandez, M., Thrippleton, M., Doubal, F. & Wardlaw, J., 15 Jun 2017, In: Current Treatment Options in Cardiovascular Medicine.

    Research output: Contribution to journalArticlepeer-review

  196. Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73-76

    Cox, S., Ritchie, S. J., Dickie, D. A., Pattie, A., Royle, N., Corley, J., Aribisala, B., Harris, S., Valdes Hernandez, M., Gow, A., Muñoz Maniega, S., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Jun 2017, In: Neurobiology of Aging. 54, p. 54-58

    Research output: Contribution to journalArticlepeer-review

  197. Molecular genetic contributions to self-rated health

    Harris, S. E., Hagenaars, S. P., Davies, G., Hill, W. D., Liewald, D. CM., Ritchie, S. J., Marioni, R. E., Sudlow, C. LM., Wardlaw, J. M., McIntosh, A. M., Gale, C. R., Deary, I. J., METASTROKE consortium, International Consortium for Blood Pressure, CHARGE consortium Aging and Longevity Group & CHARGE consortium Cognitive Group, Jun 2017, In: International Journal of Epidemiology. 46, 3, p. 994-1009

    Research output: Contribution to journalArticlepeer-review

  198. Detection of interferon alpha protein reveals differential levels and cellular sources in disease

    Rodero, M. P., Decalf, J., Bondet, V., Hunt, D., Rice, G. I., Werneke, S., McGlasson, S. L., Alyanakian, M-A., Bader-Meunier, B., Barnerias, C., Bellon, N., Belot, A., Bodemer, C., Briggs, T. A., Desguerre, I., Frémond, M-L., Hully, M., van den Maagdenberg, A. MJM., Melki, I., Meyts, I. & 15 others, Musset, L., Pelzer, N., Quartier, P., Terwindt, G. M., Wardlaw, J., Wiseman, S., Rieux-Laucat, F., Rose, Y., Neven, B., Hertel, C., Hayday, A., Albert, M. L., Rozenberg, F., Crow, Y. J. & Duffy, D., 1 May 2017, In: Journal of Experimental Medicine. 214, 5, p. 1547-1555

    Research output: Contribution to journalArticlepeer-review

  199. Continuing or Temporarily Stopping Pre-Stroke Antihypertensive Medication in Acute Stroke: An Individual Patient Data Meta-Analysis

    Woodhouse, L. J., Manning, L., Potter, J. F., Berge, E., Sprigg, N., Wardlaw, J., Lees, K. R., Bath, P. M., Robinson, T. G. & Blood Pressure in Acute Stroke Collaboration, May 2017, In: Hypertension. 69, 5, p. 933-+ 28 p.

    Research output: Contribution to journalArticlepeer-review

  200. Fatigue and cognitive function in systemic lupus erythematosus: associations with white matter microstructural damage. A diffusion tensor MRI study and meta-analysis

    Wiseman, S., Bastin, M., Hamilton, I., Hunt, D., Ritchie, S. J., Amft, N., Thomson, S., Belch, J. F. F., Ralston, S. & Wardlaw, J., May 2017, In: Lupus. 26, 6, p. 588-597

    Research output: Contribution to journalArticlepeer-review

  201. Hippocampal morphology and cognitive functions in community-dwelling older people: the Lothian Birth Cohort 1936

    Valdés Hernández, M. D. C., Cox, S. R., Kim, J., Royle, N. A., Muñoz Maniega, S., Gow, A., Anblagan, D., Bastin, M. E., Park, J., Starr, J. M., Wardlaw, J. M. & Deary, I. J., 30 Apr 2017, In: Neurobiology of Aging. 52, p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

  202. Lateral thinking – interocular symmetry and asymmetry in neurovascular patterning, in health and disease

    Cameron, J., Megaw, R., Tatham, A., McGrory, S., MacGillivray, T., Doubal, F., Wardlaw, J., Trucco, E., Chandran, S. & Dhillon, B., 28 Apr 2017, In: Progress in Retinal and Eye Research.

    Research output: Contribution to journalArticlepeer-review

  203. Cerebral white matter hypoperfusion increases with small vessel disease burden. Data from the IST-3 trial

    Arba, F., Mair, G., Carpenter, T., Sakka, E., Sandercock, P., Lindley, R., Inzitari, D. & Wardlaw, J., 15 Mar 2017, In: Journal of Stroke and Cerebrovascular Diseases.

    Research output: Contribution to journalArticlepeer-review

  204. Penumbra and re-canalization acute computed tomography in ischemic stroke evaluation: PRACTISE study protocol

    El Tawil, S., Wardlaw, J., Ford, I., Mair, G., Robinson, T., Kalra, L. & Muir, K. W., 14 Mar 2017, In: International Journal of Stroke.

    Research output: Contribution to journalArticlepeer-review

  205. Improving data availability for brain image biobanking in healthy subjects: practice-based suggestions from an international multidisciplinary working group

    Shenkin, S. D., Pernet, C., Nichols, T. E., Poline, J. B., Matthews, P. M., van der Lugt, A., Mackay, C. E., Lanyon, L. J., Mazoyer, B., Boardman, J. P., Thompson, P. M., Fox, N. C., Marcus, D. S., Sheikh, A., Cox, S. R., Anblagan, D., Job, D. E., Dickie, D. A., Rodriguez, D. & Wardlaw, J. M., 14 Feb 2017, In: NeuroImage.

    Research output: Contribution to journalArticlepeer-review

  206. Early life risk factors for cerebrovascular disease: A systematic review and meta-analysis

    Backhouse, E. V., McHutchison, C. A., Cvoro, V., Shenkin, S. D. & Wardlaw, J. M., 10 Feb 2017, In: Neurology.

    Research output: Contribution to journalArticlepeer-review

  207. Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke

    Mair, G., von Kummer, R., Adami, A., White, P. M., Adams, M. E., Yan, B., Demchuk, A. M., Farrall, A. J., Sellar, R. J., Sakka, E., Palmer, J., Perry, D., Lindley, R. I., Sandercock, P. A. G., Wardlaw, J. M. & IST-3 Collaborative Group, 1 Feb 2017, In: Stroke. 48, 2, p. 353-360

    Research output: Contribution to journalArticlepeer-review

  208. Integrity of normal-appearing white matter: influence of age, visible lesion burden and hypertension in patients with small vessel disease

    Muñoz Maniega, S., Chappell, F. M., Valdés Hernández, M. C., Armitage, P. A., Makin, S. D., Heye, A. K., Thrippleton, M. J., Sakka, E., Shuler, K., Dennis, M. S. & Wardlaw, J. M., 1 Feb 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 2, p. 644-656 13 p.

    Research output: Contribution to journalArticlepeer-review

  209. Mediterranean-type diet and brain structural change from 73 to 76 years in a Scottish cohort

    Luciano, M., Corley, J., Cox, S., Valdes Hernandez, M., Craig, L., Dickie, D. A., Karama, S., Mcneill, G., Bastin, M., Wardlaw, J. & Deary, I., 31 Jan 2017, In: Neurology. 88, 5, p. 449-455

    Research output: Contribution to journalArticlepeer-review

  210. Impact of small vessel disease in the brain on gait and balance

    Pinter, D., Ritchie, S. J., Doubal, F., Gattringer, T., Morris, Z., Bastin, M., Valdes Hernandez, M., Royle, N., Corley, J., Muñoz Maniega, S., Pattie, A., Dickie, D. A., Staals, J., Gow, A., Starr, J., Deary, I., Enzinger, C., Fazekas, F. & Wardlaw, J., 30 Jan 2017, In: Scientific Reports. 7, 41637.

    Research output: Contribution to journalArticlepeer-review

  211. Novel genetic loci associated with hippocampal volume

    Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., Mckay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C., Cichon, S., Cookson, M. R., Corvin, A., Crespo-facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack Jr, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J., Mattay, V. S., Mcdonald, C., Mcintosh, A. M., Mcmahon, F. J., Mcmahon, K. L., Mecocci, P., Melle, I., Meyer-lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Valdes Hernandez, M., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van ’t Ent, D., Van Tol, M., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., 18 Jan 2017, In: Nature Communications. 8, 13624.

    Research output: Contribution to journalArticlepeer-review

  212. Intensive versus guideline blood pressure and lipid lowering in patients with previous stroke: main results from the pilot ‘Prevention Of Decline in Cognition After Stroke Trial’ (PODCAST) randomised controlled trial

    Bath, P. M., Scutt, P., Blackburn, D. J., Ankolekar, S., Krishnan, K., Ballard, C., Burns, A., Mant, J., Passmore, P. A., Pocock, S. J., Reckless, J., Sprigg, N., Stewart, R., Wardlaw, J. & Ford, G. A., 17 Jan 2017, In: PLoS ONE. 12, 1, e0164608.

    Research output: Contribution to journalArticlepeer-review

  213. Whole brain magnetic resonance image atlases: a systematic review of existing atlases and caveats for use in population imaging

    Dickie, D., Shenkin, S., Anblagan, D., Lee, J. Y., Blesa Cabez, M., Rodriguez, D., Boardman, J., Waldman, A., Job, D. & Wardlaw, J., 4 Jan 2017, In: Frontiers in Neuroinformatics. 11, p. 1 1 p.

    Research output: Contribution to journalArticlepeer-review

  214. Brain Lesion Segmentation through Image Synthesis and Outlier Detection

    Bowles, C., Qin, C., Guerrero, R., Gunn, R., Hammers, A., Dickie, D. A., Valdes Hernandez, M., Wardlaw, J. & Rueckert, D., 2017, In: NeuroImage: Clinical. 16, p. 643-658

    Research output: Contribution to journalArticlepeer-review

  215. The application of retinal fundus camera imaging in dementia: a systematic review

    McGrory, S., Cameron, J., Pellegrini, E., Warren, C., Doubal, F., Deary, I., Dhillon, B., Wardlaw, J., Trucco, E. & MacGillivray, T., 2017, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 6, p. 91-107

    Research output: Contribution to journalArticlepeer-review

  216. 2016
  217. Novel genetic loci underlying human intracranial volume identified through genome-wide association

    Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., Van der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 others, Armstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-Partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., McKay, D. R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., Van der Grond, J., Van der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C-Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Geus, E. J. C., De Jager, P. L., de Zubicaray, G. I., Delanty, N., Depondt, C., DeStefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B-C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J-J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jr, C. R. J., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Jr, W. T. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J-L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, K. L., McMahon, F. J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van der Brug, M., Van der Lugt, A., Van der Wee, N. J. A., Van Duijn, C. M., Van Haren, N. E. M., Van 't Ent, D., Van Tol, M-J., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., DeCarli, C., Schmidt, H., Martin, N. G., De Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., 31 Dec 2016, In: Nature Neuroscience. 19, 12, p. 1569–1582 14 p.

    Research output: Contribution to journalArticlepeer-review

  218. Developing an integrated image bank and metadata for large scale research in cerebrovascular disease: our experience from the Stroke Image Bank Project

    Danso, S., Wardlaw, J., Sandercock, P., Job, D., Dickie, D. A., Rodriguez Gonzalez, D., Palmer, J. & Bath, P., 26 Dec 2016, In: Frontiers in ICT. 3, 32.

    Research output: Contribution to journalArticlepeer-review

  219. Ageing and brain white matter structure in 3513 UK Biobank participants

    Cox, S. R., Ritchie, S. J., Tucker-Drob, E. M., Liewald, D. C., Hagenaars, S. P., Davies, G., Wardlaw, J. M., Gale, C. R., Bastin, M. E. & Deary, I. J., 15 Dec 2016, In: Nature Communications. 7, 13 p., 13629.

    Research output: Contribution to journalArticlepeer-review

  220. Carotid disease at age 73 and cognitive change from age 70 to 76 years. A longitudinal cohort study

    Wardlaw, J., Allerhand, M., Eadie, E., Thomas, A., Corley, J., Pattie, A., Taylor, A., Shenkin, S., Cox, S., Gow, A., Starr, J. & Deary, I., 14 Dec 2016, In: Journal of Cerebral Blood Flow and Metabolism. p. 271678X16683693

    Research output: Contribution to journalArticlepeer-review

  221. Frequency and predictors of dysphagia in patients with recent small subcortical infarcts

    Fandler, S., Gattringer, T., Eppinger, S., Doppelhofer, K., Pinter, D., Niederkorn, K., Enzinger, C., Wardlaw, J. & Fazekas, F., 6 Dec 2016, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  222. Mortality after thrombolysis – Authors’ reply

    Berge, E., Cohen, G. R., Whiteley, W., Wardlaw, J. & Sandercock, P., 1 Dec 2016, In: Lancet Neurology.

    Research output: Contribution to journalComment/debate

  223. Effect of Right Insular Involvement on Death and Functional Outcome after Acute Ischemic Stroke in the IST-3 Trial

    Sposato, L. A., Cohen, G., Wardlaw, J. M., Sandercock, P., Lindley, R. I., Hachinski, V., IST-3 Expert Reading Panel & IST-3 Collaborative Grp, Dec 2016, In: Stroke. 47, 12, p. 2959-2965 7 p.

    Research output: Contribution to journalArticlepeer-review

  224. Endothelial function, inflammation, thrombosis and basal ganglia perivascular spaces in patients with stroke

    Wang, X., Chappell, F., Valdes Hernandez, M., Lowe, G. D. O., Rumley, A., Shuler, K., Doubal, F. & Wardlaw, J., Dec 2016, In: Journal of Stroke and Cerebrovascular Diseases. 25, 12

    Research output: Contribution to journalArticlepeer-review

  225. METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration. An initiative of the Joint Programme for Neurodegenerative Disease research

    METACOHORTS Consortium, Dec 2016, In: Alzheimer's & Dementia. 12, 12

    Research output: Contribution to journalArticlepeer-review

  226. Cerebral small vessel disease burden is increased in systemic lupus erythematosus

    Wiseman, S. J., Bastin, M. E., Jardine, C. L., Barclay, G., Hamilton, I. F., Sandeman, E., Hunt, D., Amft, N., Thomson, S., Belch, J. F. F., Ralston, S. H. & Wardlaw, J. M., 30 Nov 2016, In: Stroke. 47, 11, p. 2722–2728 7 p.

    Research output: Contribution to journalArticlepeer-review

  227. Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

    Hagenaars, S. P., Harris, S. E., Davies, G., Hill, W. D., Liewald, D. C. M., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Cullen, B., Malik, R., METASTROKE Consortium, International Consortium for Blood Pressure GWAS, SpiroMeta Consortium, CHARGE Consortium Pulmonary Group, CHARGE consortium Aging and Longevity Group, Worrall, B. B., Sudlow, C. L. M., Wardlaw, J. M., Gallacher, J., Pell, J. & 4 others, McIntosh, A. M., Smith, D. J., Gale, C. R. & Deary, I. J., 30 Nov 2016, In: Molecular Psychiatry. 21, 11, p. 1624-1632 9 p.

    Research output: Contribution to journalArticlepeer-review

  228. Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

    Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S-J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikäinen, L-P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., van Setten, J., Smith, A. V. & 31 others, Vojinovic, D., Yanek, L. R., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y-D. I., Cupples, L. A., de Jong, P. A., de Koning, H., de Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Išgum, I., Jukema, J. W., Kähönen, M., Kardia, S. L. R., Kral, B. G., Wardlaw, J. M., Deary, I. J., Wilson, J. G. & CHARGE Consortium, 21 Nov 2016, In: Circulation: Cardiovascular Genetics.

    Research output: Contribution to journalArticlepeer-review

  229. STROKOG (Stroke and Cognition consortium): An international consortium to examine the epidemiology, diagnosis and treatment of neurocognitive disorders in relation to cerebrovascular disease

    Sachdev, P. S., Lo, J. W., Crawford, J., Mellon, L., Hickey, A., Williams, D., Bordet, R., Mendyk, A-M., Gelé, P., Deplanque, D., Bae, H-J., Lim, J-S., Brodtmann, A., Werden, E., Cumming, T., Köhler, S., Verhey, F. R. J., Dong, Y-H., Tan, H. H., Chen, C. & 46 others, Kalaria, R. N., Allan, L. M., Akinyemi, R. O., Ogunniyi, A., Klimkowicz-Mrowiec, A., Dichgans, M., Wollenweber, F. A., Zietemann, V., Hoffmann, M., Desmond, D. W., Linden, T., Blomstrand, C., Fagerberg, B., Skoog, I., Godefroy, O., Barbay, M., Roussel, M., Lee, B-C., Yu, K-H., Wardlaw, J., Makin, S., Doubal, F., Chappell, F., Srikanth, V., Thrift, A. G., Donnan, G. A., Kandiah, N., Chander, R. J., Lin, X., Cordonnier, C., Moulin, S., Rossi, C., Sabayan, B., Stott, D. J., Jukema, J. W., Melkas, S., Jokinen, H., Erkinjuntti, T., Mok, V. C. T., Wong, A., Lam, B. Y. K., Leys, D., Hénon, H., Bombois, S., Lipnicki, D. M. & Kochan, N. A., 18 Nov 2016, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalArticlepeer-review

  230. Inter-hemispheric characterisation of small vessel disease imaging markers after subcortical infarct

    Valdes Hernandez, M., Qiu, X., Wang, X., Wiseman, S., Sakka, E., Maconick, L. C., Doubal, F., Sudlow, C. & Wardlaw, J., 3 Nov 2016, In: Brain and Behavior.

    Research output: Contribution to journalArticlepeer-review

  231. Endovascular therapy for acute ischaemic stroke: the Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE) randomised, controlled trial

    Muir, K. W., Ford, G. A., Messow, C-M., Ford, I., Murray, A., Clifton, A., Brown, M. M., Madigan, J., Lenthall, R., Robertson, F., Dixit, A., Cloud, G. C., Wardlaw, J., Freeman, J., White, P. & PISTE Investigators, 18 Oct 2016, In: Journal of Neurology, Neurosurgery & Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  232. Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex

    Guadalupe, T., Mathias, S. R., vanErp, T. G. M., Whelan, C. D., Zwiers, M. P., Abe, Y., Abramovic, L., Agartz, I., Andreassen, O. A., Arias-Vásquez, A., Aribisala, B. S., Armstrong, N. J., Arolt, V., Artiges, E., Ayesa-Arriola, R., Baboyan, V. G., Banaschewski, T., Barker, G., Bastin, M. E., Baune, B. T. & 141 others, Blangero, J., Bokde, A. L. W., Boedhoe, P. S. W., Bose, A., Brem, S., Brodaty, H., Bromberg, U., Brooks, S., Büchel, C., Buitelaar, J., Calhoun, V. D., Cannon, D. M., Cattrell, A., Cheng, Y., Conrod, P. J., Conzelmann, A., Corvin, A., Crespo-Facorro, B., Crivello, F., Dannlowski, U., de Zubicaray, G. I., de Zwarte, S. M. C., Deary, I. J., Desrivières, S., Doan, N. T., Donohoe, G., Dørum, E. S., Ehrlich, S., Espeseth, T., Fernández, G., Flor, H., Fouche, J-P., Frouin, V., Fukunaga, M., Gallinat, J., Garavan, H., Gill, M., Suarez, A. G., Gowland, P., Grabe, H. J., Grotegerd, D., Gruber, O., Hagenaars, S., Hashimoto, R., Hauser, T. U., Heinz, A., Hibar, D. P., Hoekstra, P. J., Hoogman, M., Howells, F. M., Hu, H., Hulshoff Pol, H. E., Huyser, C., Ittermann, B., Jahanshad, N., Jönsson, E. G., Jurk, S., Kahn, R. S., Kelly, S., Kraemer, B., Kugel, H., Kwon, J. S., Lemaitre, H., Lesch, K-P., Lochner, C., Luciano, M., Marquand, A. F., Martin, N. G., Martínez-Zalacaín, I., Martinot, J-L., Mataix-Cols, D., Mather, K., McDonald, C., McMahon, K. L., Medland, S. E., Menchón, J. M., Morris, D. W., Mothersill, O., Maniega, S. M., Mwangi, B., Nakamae, T., Nakao, T., Narayanaswaamy, J. C., Nees, F., Nordvik, J. E., Onnink, A. M. H., Opel, N., Ophoff, R., Paillère Martinot, M-L., Papadopoulos Orfanos, D., Pauli, P., Paus, T., Poustka, L., Reddy, J. Y., Renteria, M. E., Roiz-Santiáñez, R., Roos, A., Royle, N. A., Sachdev, P., Sánchez-Juan, P., Schmaal, L., Schumann, G., Shumskaya, E., Smolka, M. N., Soares, J. C., Soriano-Mas, C., Stein, D. J., Strike, L. T., Toro, R., Turner, J. A., Tzourio-Mazoyer, N., Uhlmann, A., Hernández, M. V., van den Heuvel, O. A., van der Meer, D., van Haren, N. E. M., Veltman, D. J., Venkatasubramanian, G., Vetter, N. C., Vuletic, D., Walitza, S., Walter, H., Walton, E., Wang, Z., Wardlaw, J., Wen, W., Westlye, L. T., Whelan, R., Wittfeld, K., Wolfers, T., Wright, M. J., Xu, J., Xu, X., Yun, J-Y., Zhao, J., Franke, B., Thompson, P. M., Glahn, D. C., Mazoyer, B., Fisher, S. E. & Francks, C., 13 Oct 2016, In: Brain imaging and behavior.

    Research output: Contribution to journalArticlepeer-review

  233. Cognitive reserve moderates long-term cognitive and functional outcome in cerebral small vessel disease

    Jokinen, H., Melkas, S., Madureira, S., Verdelho, A., Ferro, J. M., Fazekas, F., Schmidt, R., Scheltens, P., Barkhof, F., Wardlaw, J., Inzitari, D., Pantoni, L. & Erkinjuntti, T., 7 Oct 2016, In: Journal of Neurology, Neurosurgery & Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  234. Associations between education and brain structure at age 73 years, adjusted for age 11 IQ

    Cox, S., Dickie, D. A., Ritchie, S. J., Karama, S., Pattie, A., Royle, N., Corley, J., Aribisala, B., Valdes Hernandez, M. C., Muñoz Maniega, S., Starr, J., Bastin, M., Evans, A. C., Wardlaw, J. & Deary, I., Oct 2016, In: Neurology. 87, 17, p. 1820-1826 7 p.

    Research output: Contribution to journalArticlepeer-review

  235. Update on cerebral small vessel disease – a dynamic, whole-brain disease

    Shi, Y. & Wardlaw, J., 30 Sep 2016, In: Stroke and Vascular Neurology.

    Research output: Contribution to journalArticlepeer-review

  236. Pseudo-Healthy Image Synthesis for White Matter Lesion Segmentation

    Bowles, C., Qin, C., Ledig, C., Moreno, R. G., Gunn, R., Hammers, A., Sakka, E., Dickie, D. A., Valdes Hernandez, M., Royle, N., Wardlaw, J., Rhodius-Meester, H., Tijms, B., Lemstra, A., van der Flier, W., Barkhof, F., Scheltens, P. & Rueckert, D., 23 Sep 2016, Simulation and Synthesis in Medical Imaging. SpringerLink, Vol. 9968. p. 87-96 (Lecture Notes in Computer Science).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  237. Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology

    Wardlaw, J. & Horsburgh, K., 22 Sep 2016, In: Clinical science.

    Research output: Contribution to journalEditorialpeer-review

  238. Early life characteristics and late life burden of cerebral small vessel disease in the Lothian Birth Cohort 1936

    Field, T. S., Doubal, F., Johnson, W., Backhouse, E., McHutchison, C., Cox, S., Corley, J., Pattie, A., Gow, A., Shenkin, S., Cvoro, V., Morris, Z., Staals, J., Bastin, M., Deary, I. & Wardlaw, J., 19 Sep 2016, In: Aging. 8, 9, p. 2039-2061

    Research output: Contribution to journalArticlepeer-review

  239. Effects of alteplase on survival after ischaemic stroke (IST-3): 3 year follow-up of a randomised, controlled, open-label trial

    Berge, E., Cohen, G., Roaldsen, M. B., Lundström, E., Isaksson, E., Rudberg, A-S., Slot, K. B., Forbes, J., Smith, J., Drever, J., Wardlaw, J. M., Lindley, R. I., Sandercock, P. A. G., Whiteley, W. N. & IST-3 collaborative group, 1 Sep 2016, In: Lancet Neurology. 15, 10, p. 1028-1034 7 p.

    Research output: Contribution to journalArticlepeer-review

  240. Enlarged perivascular spaces and cognitive impairment after stroke and transient ischemic attack

    Arba, F., Quinn, T. J., Hankey, G. J., Lees, K. R., Wardlaw, J., Ali, M. & Inzitari, D., 19 Aug 2016, In: International Journal of Stroke.

    Research output: Contribution to journalArticlepeer-review

  241. Effects of alteplase for acute stroke on the distribution of functional outcomes: a pooled analysis of nine trials

    Lees, K. R., Emberson, J., Blackwell, L., Bluhmki, E., Davis, S., Donnan, G. A., Grotta, J. C., Kaste, M., von Kummer, R., Lansberg, M. G., Lindley, R., Lyden, P., Murray, G., Sandercock, P., Toni, D., Toyoda, K., Wardlaw, J., Whiteley, W., Baigent, C., Hacke, W. & 1 others, Howard, G., 9 Aug 2016, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  242. Cerebral blood flow in small vessel disease: a systematic review and meta-analysis

    Shi, Y., Thrippleton, M., Makin, S., Marshall, I., Geerlings, M. I., de Craen, A. J. M., Van Buchem, M. A. & Wardlaw, J., 5 Aug 2016, In: Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalArticlepeer-review

  243. Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis

    for the Stroke Thrombolysis Trialists' Collaborative Group, 1 Aug 2016, In: Lancet Neurology. 15, 9, p. 925-933 9 p.

    Research output: Contribution to journalArticlepeer-review

  244. Brain white matter structure and information processing speed in healthy older age

    Kuznetsova, K., Muñoz Maniega, S., Ritchie, S. J., Cox, S. R., Storkey, A. J., Starr, J. M., Wardlaw, J. M., Deary, I. J. & Bastin, M. E., 31 Jul 2016, In: Brain Structure and Function. 221, 6, p. 3223-3235

    Research output: Contribution to journalArticlepeer-review

  245. Application of the ordered logit model to optimising Frangi filter parameters for segmentation of perivascular spaces

    Ballerini, L., Lovreglio, R., Valdes Hernandez, M., Gonzalez-Castro, V., Muñoz Maniega, S., Pellegrini, E., Bastin, M., Deary, I. & Wardlaw, J., 25 Jul 2016, In: Procedia Computer Science. p. 61-67

    Research output: Contribution to journalArticlepeer-review

  246. Texture-based classification for the automatic rating of the perivascular spaces in brain MRI

    Gonzalez-Castro, V., Valdes Hernandez, M., Armitage, P. & Wardlaw, J., 25 Jul 2016, In: Procedia Computer Science. 90, p. 9-14

    Research output: Contribution to journalArticlepeer-review

  247. Automatic rating of perivascular spaces in brain MRI using bag of visual words

    Gonzalez-Castro, V., Valdes Hernandez, M., Armitage, P. & Wardlaw, J., 1 Jul 2016, Image Analysis and Recognition. SpringerLink, Vol. 9730. (Lecture Notes in Computer Science).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  248. Do white matter hyperintensities mediate the association between brain iron deposition and cognitive abilities in older people?

    Valdes Hernandez, M., Allerhand, M., Glatz, A., Clayson, L., Munoz-Maniega, S., Gow, A., Royle, N., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., Jul 2016, In: European Journal of Neurology. 23, p. 1202-1209

    Research output: Contribution to journalArticlepeer-review

  249. 3D shape analysis of the brain's third ventricle using a midplane encoded symmetric template model

    Kim, J., Valdes Hernandez, M., Royle, N., Muñoz Maniega, S., Aribisala, B., Gow, A., Bastin, M., Deary, I., Wardlaw, J. & Park, J., Jun 2016, In: Computer methods and programs in biomedicine. 129, p. 51-62

    Research output: Contribution to journalArticlepeer-review

  250. Vascular risk factors and progression of white matter hyperintensities in the Lothian Birth Cohort 1936

    Dickie, D. A., Ritchie, S. J., Cox, S., Sakka, E., Royle, N., Aribisala, B., Valdes Hernandez, M., Muñoz Maniega, S., Pattie, A., Corley, J., Starr, J., Bastin, M., Deary, I. & Wardlaw, J., Jun 2016, In: Neurobiology of Aging. 42, p. 116-123

    Research output: Contribution to journalArticlepeer-review

  251. Reproducibility and variability of quantitative MRI markers in cerebral small vessel disease

    De Guio, F., Jouvent, E., Biessels, G. J., Black, SE., Brayne, C., Chen, C., Cordonnier, C., de Leeuw, F-E., Dichgans, M., Doubal, F., Duering, M., Dufouil, C., Duzel, E., Fazekas, F., Hachinski, V., Ikram, M. A., Linn, J., Matthews, P. M., Mazoyer, B., Mok, V. & 21 others, Norrving, B., O'Brien, J. T., Pantoni, L., Ropele, S., Sachdev, P. S., Schmidt, R., Seshadri, S., Smith, E. E., Sposato, LA., Stephan, B., Swartz, R., Tzourio, C., van Buchem, M., van der Lugt, A., van Oostenbrugge, R., Vernooij, M. W., Viswanathan, A., Werring, D., Wollenweber, F., Wardlaw, J. & Chabriat, H., 11 May 2016, In: Journal of Cerebral Blood Flow and Metabolism.

    Research output: Contribution to journalArticlepeer-review

  252. IST-3 stroke trial data available

    Sandercock, P., Wardlaw, J., Lindley, R., Whiteley, W. & Cohen, G., 7 May 2016, In: The Lancet. 387, 10031

    Research output: Contribution to journalLetterpeer-review

  253. Continuing versus Stopping Prestroke Antihypertensive Therapy in Acute Intracerebral Hemorrhage: A Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke Trial

    Krishnan, K., Scutt, P., Woodhouse, L., Adami, A., Becker, J. L., Cala, L. A., Casado, A. M., Chen, C., Dineen, R. A., Gommans, J., Koumellis, P., Christensen, H., Collins, R., Czlonkowska, A., Lees, K. R., Ntaios, G., Ozturk, S., Phillips, S. J., Sprigg, N., Szatmari, S. & 2 others, Wardlaw, J. M. & Bath, P. M., 1 May 2016, In: Journal of Stroke and Cerebrovascular Diseases. 25, 5, p. 1017-1026 10 p.

    Research output: Contribution to journalArticlepeer-review

  254. Imaging signatures of meningioma and low-grade glioma: a diffusion tensor, magnetization transfer and quantitative longitudinal relaxation time MRI study

    Piper, R. J., Mikhael, S., Wardlaw, J., Laidlaw, D. H., Whittle, I. & Bastin, M., May 2016, In: Magnetic Resonance Imaging. 34, p. 596-602

    Research output: Contribution to journalArticlepeer-review

  255. Magnetic Resonance Imaging for Assessment of Cerebrovascular Reactivity in Cerebral Small Vessel Disease. A Systematic Review.

    Blair, G., Doubal, F., Thrippleton, M., Marshall, I. & Wardlaw, J., May 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, p. 833-41

    Research output: Contribution to journalArticlepeer-review

  256. Observer reliability of CT Perfusion scans

    El Tawil, S., Mair, G., Huang, X., Sakka, E., Palmer, J., Ford, I., Kalra, L., Muir, K. & Wardlaw, J., May 2016, p. 447-448. 2 p.

    Research output: Contribution to conferencePosterpeer-review

  257. Visual Scoring Versus Computational Volume Measures of Perfusion Defects In Acute Ischaemic Stroke

    Mair, G., Carpenter, T., Cohen, G., Lindley, R., Sandercock, P. & Wardlaw, J., May 2016, p. 458. 1 p.

    Research output: Contribution to conferencePosterpeer-review

  258. Cytomegalovirus infection is associated with an increase in systolic blood pressure in older individuals

    Firth, C., Wardlaw, J., Ritchie, S. J., Ferro, C. J., Deary, I., Starr, J. & Moss, P., 12 Apr 2016, In: QJM: An International Journal of Medicine. 109, 9, p. 595-600 hcw026.

    Research output: Contribution to journalArticlepeer-review

  259. Cerebrovascular disease in rheumatic diseases. A systematic review and meta-analysis

    Wiseman, S., Ralston, S. & Wardlaw, J., Apr 2016, In: Stroke. 47, p. 943-950

    Research output: Contribution to journalArticlepeer-review

  260. Trait Conscientiousness and the Personality Meta-Trait Stability are Associated with Regional White Matter Microstructure

    Lewis, G. J., Cox, S., Booth, T., Muñoz Maniega, S., Royle, N., Valdes Hernandez, M., Wardlaw, J., Bastin, M. & Deary, I., 24 Mar 2016, In: Social Cognitive and Affective Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  261. Author Response: ABCD2 score and secondary stroke prevention: Meta-analysis and effect per 1,000 patients triaged

    Wardlaw, J. M., Brazzelli, M., Chappell, F., Dennis, M. S. & Sandercock, P. A. G., 16 Feb 2016, In: Neurology. 86, 7, p. 697 1 p.

    Research output: Contribution to journalLetterpeer-review

  262. Polygenic risk of ischemic stroke is associated with cognitive ability

    Harris, S. E., Malik, R., Marioni, R., Campbell, A., Seshadri, S., Worrall, B. B., Sudlow, C. L. M., Hayward, C., Bastin, M. E., Starr, J. M., Porteous, D. J., Wardlaw, J. M., Deary, I. J. & METASTROKE Consortium, 16 Feb 2016, In: Neurology. 86, 7, p. 611-618 8 p.

    Research output: Contribution to journalArticlepeer-review

  263. A structural and functional magnetic resonance imaging dataset of brain tumour patients.

    Pernet, C., Krzysztof, G., Job, D., Rodriguez Gonzalez, D., Whittle, I. & Wardlaw, J., 2 Feb 2016, In: Scientific Data. 6 p., 160003.

    Research output: Contribution to journalArticlepeer-review

  264. Cerebral small vessel disease: capillary pathways to stroke and cognitive decline

    Ostergaard, L., Sondergaard, T., Moreton, F., Hansen, MB., Wardlaw, J., Dalkara, T., Markus, H. S. & Muir, K., Feb 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 2, p. 302-325

    Research output: Contribution to journalArticlepeer-review

  265. Evaluation of a pre-surgical functional MRI workflow: From data acquisition to reporting

    Pernet, C., Krzysztof, G., Job, D., Rodriguez Gonzalez, D., Storkey, A., Whittle, I. & Wardlaw, J., Feb 2016, In: International journal of medical informatics. 86, p. 37-42 6 p.

    Research output: Contribution to journalArticlepeer-review

  266. Identification of imaging selection patterns in acute ischemic stroke patients and the influence on treatment and clinical trial enrolment decision making

    Luby, M., Warach, S. J., Albers, G. W., Baron, JC., Cognard, C., Dávalos, A., Donnan, G. A., Fiebach, JB., Fiehler, J., Hacke, W., Lansberg, M. G., Liebeskind, DS., Mattle, H. P., Oppenheim, C., Schellinger, P. D., Wardlaw, J. & Wintermark, M., Feb 2016, In: International Journal of Stroke. 11, p. 180-190

    Research output: Contribution to journalArticlepeer-review

  267. A brain imaging repository of normal structural MRI across the life course: Brain Images of Normal Subjects (BRAINS)

    Job, D., Dickie, D. A., Rodriguez Gonzalez, D., Robson, A., Danso, S., Pernet, C., Bastin, M., Boardman, J. P., Murray, A. D., Ahearn, T. S., Waiter, G. D., Staff, R. T., Deary, I., Shenkin, S. D. & Wardlaw, J., 18 Jan 2016, In: NeuroImage.

    Research output: Contribution to journalArticlepeer-review

  268. Development and initial evaluation of a semi-automatic approach to assess perivascular spaces on conventional magnetic resonance images

    Wang, X., Valdes Hernandez, M., Doubal, F., Chappell, F., Piper, R. J., Deary, I. & Wardlaw, J., 15 Jan 2016, In: Journal of Neuroscience Methods. 257, p. 34-44

    Research output: Contribution to journalArticlepeer-review

  269. Effect of alteplase on the CT hyperdense artery sign and functional outcome after ischemic stroke

    Mair, G., von Kummer, R., Morris, Z., von Heijne, A., Bradey, N., Cala, L., Peeters, A., Farrall, A., Adami, A., Potter, G., Cohen, G., Sandercock, P., Lindley, R., Wardlaw, J. & IST-3 Collaborative Group, 12 Jan 2016, In: Neurology. 86, p. 1-8

    Research output: Contribution to journalArticlepeer-review

  270. Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke

    Traylor, M., Zhang, CR., Adib-samii, P., Devan, WJ., Parsons, OE., Lanfranconi, S., Gregory, S., Cloonan, L., Falcone, GJ., Radmanesh, F., Fitzpatrick, K., Kanakis, A., Barrick, T. R., Moynihan, B., Lewis, CM., Boncoraglio, G., Lemmens, R., Thijs, V., Sudlow, C., Wardlaw, J. & 11 others, Rothwell, P. M., Meschia, J. F., Worrall, B. B., Levi, C., Bevan, S., Furie, K. L., Dichgans, M., Rosand, J., Markus, H. S., Rost, NS. & the International Stroke Genetics Consortium, 12 Jan 2016, In: Neurology. 86, p. 146-153

    Research output: Contribution to journalArticlepeer-review

  271. Blood pressure and sodium: association with MRI markers in cerebral small vessel disease

    Heye, A. K., Thrippleton, M., Chappell, F., Valdes Hernandez, M., Armitage, P., Makin, S., Munoz-Maniega, S., Sakka, E., Flatman, P., Dennis, M. & Wardlaw, J., Jan 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, p. 264-274

    Research output: Contribution to journalArticlepeer-review

  272. Consensus statement for diagnosis of subcortical small vessel disease

    Rosenberg, GA., Wallin, A., Wardlaw, J., Markus, H. S., Montaner, J., Wolfson, L., Iadecola, C., Zlokovic, BV., Joutel, A., Dichgans, M., Duering, M., Schmidt, R., Koczyn, A., Grinberg, LT., Chui, HC. & Hachinski, V., Jan 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, p. 6-25

    Research output: Contribution to journalArticlepeer-review

  273. Tracer kinetic modelling for DCE-MRI quantification of subtle blood–brain barrier permeability

    Heye, A. K., Thrippleton, M. J., Armitage, P. A., del C. Valdés Hernández, M., Makin, S. D., Glatz, A., Sakka, E. & Wardlaw, J. M., Jan 2016, In: NeuroImage. 125, p. 446–455 10 p.

    Research output: Contribution to journalArticlepeer-review

  274. A Tool For Gyral Ground Truth Measurements

    Mikhael, S., Gray, C., MacGillivray, T., Murray, A., Hoogendoorn, C., Valdes Hernandez, M., Wardlaw, J. & Pernet, C., 2016.

    Research output: Contribution to conferencePaperpeer-review

  275. Effect of treatment delay, stroke type, and thrombolysis on the effect of glyceryl trinitrate, a nitric oxide donor, on outcome after acute stroke: a systematic review and meta-analysis of individual patient from randomised trials

    Bath, P. M. W., Woodhouse, L., Krishnan, K., Anderson, C., Berge, E., Ford, G., Robinson, T., Saver, JL., Sprigg, N. & Wardlaw, J., 2016, In: Stroke research and treatment. 2016

    Research output: Contribution to journalArticlepeer-review

  276. Volumetric and correlational implications of brain parcellation method selection: a 3-way comparison in the frontal lobes.

    Cox, S., McKenzie, T., Aribisala, B., Royle, N., MacPherson, S. E., Maclullich, A., Bastin, M., Wardlaw, J., Deary, I. & Ferguson, K., 2016, In: Journal of computer assisted tomography. 40, p. 53-60

    Research output: Contribution to journalArticlepeer-review

  277. 2015
  278. Effect of X-Ray Attenuation of Arterial Obstructions on Intravenous Thrombolysis and Outcome after Ischemic Stroke

    Mair, G., von Kummer, R., Lindley, R., Sandercock, P., Wardlaw, J. & IST-3 Collaborative Group, 23 Dec 2015, In: PLoS ONE. 10, e0145683.

    Research output: Contribution to journalArticlepeer-review

  279. Progression of white matter disease and cortical thinning are not related in older community-dwelling subjects

    Dickie, D. A., Karama, S., Ritchie, S. J., Cox, S. R., Sakka, E., Royle, N. A., Aribisala, B. S., Hernández, M. V., Maniega, S. M., Pattie, A., Corley, J., Starr, J. M., Bastin, M. E., Evans, A. C., Deary, I. J. & Wardlaw, J. M., 22 Dec 2015, In: Stroke. 47, 2, p. 410-6 7 p.

    Research output: Contribution to journalArticlepeer-review

  280. Rationale, design and methodology of the image analysis protocol for studies of patients with cerebral small vessel disease and mild stroke

    Valdes Hernandez, M., Armitage, P., Thrippleton, M., Chappell, F., Sandeman, E. M., Munoz-Maniega, S., Shuler, K. & Wardlaw, J., 18 Dec 2015, In: Brain and Behavior. 5, 12

    Research output: Contribution to journalArticlepeer-review

  281. Glyceryl Trinitrate for Acute Intracerebral Hemorrhage. Results From the Efficacy of Nitric Oxide in Stroke (ENOS) Trial, a Subgroup Analysis

    Krishnan, K., Scutt, P., Woodhouse, L., Adami, A., Becker, JL., Berge, E., Cala, L., Casado, A., Caso, V., Chen, C., Christensen, H., Collins, R., Czlonkowska, A., Lees, K. R., Ntaios, G., Ozturk, S., Phillips, S. J., Pocock, S. J., de Silva, A., Sprigg, N. & 3 others, Szatmari, S., Wardlaw, J. & Bath, P. M. W., 8 Dec 2015, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  282. ENIGMA and the individual: Predicting factors that affect the brain in 35 countries worldwide

    Thompson, P. M., Andreassen, O. A., Arias-Vasquez, A., Bearden, C. E., Boedhoe, P. S., Brouwer, R. M., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cannon, D. M., Cohen, R. A., Conrod, P. J., Dale, A. M., Deary, I. J., Dennis, E. L., de Reus, M. A., Desrivieres, S., Dima, D., Donohoe, G., Fisher, S. E. & 31 others, Fouche, J-P., Francks, C., Frangou, S., Franke, B., Ganjgahi, H., Garavan, H., Glahn, D. C., Grabe, H. J., Guadalupe, T., Gutman, B. A., Hashimoto, R., Hibar, D. P., Holland, D., Hoogman, M., Pol, H. E. H., Hosten, N., Jahanshad, N., Kelly, S., Kochunov, P., Kremen, W. S., Lee, P. H., Mackey, S., Martin, N. G., Mazoyer, B., McDonald, C., Medland, S. E., Morey, R. A., Nichols, T. E., Paus, T., Wardlaw, J. M. & ENIGMA Consortium, 4 Dec 2015, In: NeuroImage.

    Research output: Contribution to journalArticlepeer-review

  283. APOE/TOMM40 genetic loci, white matter hyperintensities and cerebral microbleeds

    Lyall, D. M., Munoz-Maniega, S., Harris, S., Bastin, M., Murray, C., Lutz, M. W., Saunders, A. M., Roses, A. D., Valdes Hernandez, M., Royle, N., Starr, J., Porteous, D., Deary, I. & Wardlaw, J., Dec 2015, In: International Journal of Stroke. 10, 8, p. 1297-1300

    Research output: Contribution to journalArticlepeer-review

  284. Brain volumetric changes and cognitive ageing during the eighth decade of life

    Ritchie, S. J., Dickie, D., Cox, S., Valdes Hernandez, M., Corley, J., Royle, N., Pattie, A., Aribisala, B., Redmond, P., Munoz-Maniega, S., Taylor, A., Sibbett, R., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Dec 2015, In: Human Brain Mapping. 36, p. 4910–4925

    Research output: Contribution to journalArticlepeer-review

  285. Permutation and parametric tests for effect sizes in voxel-based morphometry of grey matter volume in brain structural MRI

    Dickie, D. A., Mikhael, S., Job, D. E., Wardlaw, J. M., Laidlaw, D. H. & Bastin, M. E., Dec 2015, In: Magnetic Resonance Imaging. 33, p. 1299-1305

    Research output: Contribution to journalArticlepeer-review

  286. Acting on incidental findings in research imaging

    Wardlaw, J. M., Davies, H., Booth, T. C., Laurie, G., Compston, A., Freeman, C., Leach, M. O., Waldman, A., Lomas, D. J., Kessler, K., Crabbe, F. & Jackson, A., 10 Nov 2015, In: British Medical Journal (BMJ). 351, p. h5190

    Research output: Contribution to journalArticlepeer-review

  287. Baseline characteristics, analysis plan and report on feasibility for the Prevention Of Decline in Cognition After Stroke Trial (PODCAST)

    Scutt, P., Daniel, B., Krishnan, K., Ballard, C., Burns, A., Ford, G. A., Mant, J., Passmore, P. A., Pocock, S. J., Reckless, J., Sprigg, N., Stewart, R., Wardlaw, J. & Bath, P. M. W., 7 Nov 2015, In: Trials. 16, p. 509

    Research output: Contribution to journalArticlepeer-review

  288. Thrombectomy for Acute Ischemic Stroke

    Wardlaw, J. M. & Dennis, M. S., 3 Nov 2015, In: Journal of the American Medical Association (JAMA). 314, 17, p. 1803-1805 3 p.

    Research output: Contribution to journalEditorialpeer-review

  289. Effect of Hyperacute Administration (Within 6 Hours) of Transdermal Glyceryl Trinitrate, a Nitric Oxide Donor, on Outcome After Stroke: Subgroup Analysis of the Efficacy of Nitric Oxide in Stroke (ENOS) Trial

    Woodhouse, L., Scutt, P., Krishnan, K., Berge, E., Gommans, J., Ntaios, G., Wardlaw, J., Sprigg, N., Bath, P. M. & ENOS Investigators, Nov 2015, In: Stroke; a journal of cerebral circulation. 46, 11, p. 3194-201 8 p.

    Research output: Contribution to journalArticlepeer-review

  290. Total MRI load of cerebral small vessel disease and cognitive ability in older people

    Staals, J., Booth, T., Morris, Z., Bastin, M. E., Gow, A. J., Corley, J., Redmond, P., Starr, J., Deary, I. J. & Wardlaw, J. M., 31 Oct 2015, In: Neurobiology of Aging. 36, 10, p. 2806-2811

    Research output: Contribution to journalArticlepeer-review

  291. Effects of blood pressure and blood pressure-lowering treatment during the first 24 hours among patients in the Third International Stroke Trial of thrombolytic treatment for acute ischemic stroke

    Berge, E., Cohen, G., Lindley, R., Sandercock, P., Wardlaw, J., Sandset, E. C. & Whiteley, W., 20 Oct 2015, In: Stroke. 46, 12, p. 3362-3369 8 p.

    Research output: Contribution to journalArticlepeer-review

  292. Brain iron deposits and lifespan cognitive ability

    Valdes Hernandez, M., Ritchie, S. J., Glatz, A., Allerhand, M., Munoz-Maniega, S., Gow, A., Royle, N., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., Oct 2015, In: AGE. 37, p. 100

    Research output: Contribution to journalArticlepeer-review

  293. Morphological MRI characteristics of recent small subcortical infarcts

    Gattringer, T., Eppinger, S., Pinter, D., Pirpamer, L., Berghold, A., Wuensch, G., Ropele, S., Wardlaw, J., Enzinger, C. & Fazekas, F., Oct 2015, In: International Journal of Stroke. 10, p. 1037-1043

    Research output: Contribution to journalArticlepeer-review

  294. Accuracy of Patient Self-Report of Stroke: A Systematic Review from the UK Biobank Stroke Outcomes Group

    UK Biobank Stroke Outcomes Group, UK Biobank Follow-up and Outcomes Working Group & Wardlaw, J., 10 Sep 2015, In: PLoS ONE. 10, 9, p. e0137538

    Research output: Contribution to journalArticlepeer-review

  295. Post-mortem brain analyses of the Lothian Birth Cohort 1936: Extending lifetime cognitive and brain phenotyping to the level of the synapse

    Henstridge, C., JAckson, R., Kim, J., Herrmann, A., Wright, A. K., Harris, S., Bastin, M., Starr, J., Wardlaw, J., Gillingwater, T., Smith, C., McKenzie, C-A., Cox, S., Deary, I. & Spires-Jones, T., 4 Sep 2015, In: Acta Neuropathologica Communications. 3, 53

    Research output: Contribution to journalArticlepeer-review

  296. Early life risk factors for stroke and cognitive impairment

    Backhouse, EV., McHutchison, C., Cvoro, V., Shenkin, S. & Wardlaw, J., Sep 2015, In: Current Epidemiology Reports. 2, 3, p. 172-179

    Research output: Contribution to journalArticlepeer-review

  297. Phase-based Metamorphosis of Diffusion Lesion in Relation to Perfusion Values in Acute Ischemic Stroke

    Rekik, I., Allassonnière, S., Luby, M., Carpenter, T. & Wardlaw, J., Sep 2015, In: NeuroImage: Clinical. 9, p. 44-49

    Research output: Contribution to journalArticlepeer-review

  298. Plasma biomarkers of inflammation, endothelial function and haemostasis in cerebral small vessel disease

    Wiseman, S., Doubal, F., Chappell, F., Valdes Hernandez, M., Wang, X., Rumley, A., Lowe, G. D. O., Dennis, M. & Wardlaw, J., Sep 2015, In: Cerebrovascular diseases. 40, 3-4, p. 157-164

    Research output: Contribution to journalArticlepeer-review

  299. Consent for brain tissue donation after intracerebral haemorrhage: a community-based study

    Samarasekera, N., Lerpiniere, C., Fonville, A., Farrall, A., Wardlaw, J., White, P., Torgersen, A., Ironside, J., Smith, C., Salman, R., Lothian Audit of the Treatment of Cerebral Haemorrhage (LATCH) collaborators & Reed, M. J., 24 Aug 2015, In: PLoS ONE. 10, 8, e0135043.

    Research output: Contribution to journalArticlepeer-review

  300. Protocol for the perfusion and angiography imaging sub-study of the Third International Stroke Trial (IST-3) of alteplase treatment within six-hours of acute ischemic stroke

    Wardlaw, J. M., von Kummer, R., Carpenter, T., Parsons, M., Lindley, R. I., Cohen, G., Murray, V., Kobayashi, A., Peeters, A., Chappell, F. & Sandercock, P. A. G., Aug 2015, In: International Journal of Stroke. 10, 6, p. 956-968

    Research output: Contribution to journalArticlepeer-review

  301. ABCD2 score and secondary stroke prevention. Meta-analysis and effect per 1000 patients triaged

    Wardlaw, J., Brazzelli, M., Chappell, F., Miranda, H., Shuler, K., Sandercock, P. & Dennis, M., 28 Jul 2015, In: Neurology. 85, p. 1-8

    Research output: Contribution to journalLiterature reviewpeer-review

  302. Beyond a bigger brain: Multivariable structural brain imaging and intelligence

    Ritchie, S., Booth, T., Valdes Hernandez, M., Corley, J., Munoz-Maniega, S., Gow, A., Royle, N., Pattie, A., Karama, S., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Jul 2015, In: Intelligence. 51, p. 47–56 10 p.

    Research output: Contribution to journalArticlepeer-review

  303. International survey of acute stroke imaging used to make revascularization treatment decisions

    Wintermark, M., Luby, M., Bornstein, N. M., Demchuk, A., Fiehler, J., Kudo, K., Lees, K. R., Liebeskind, D. S., Michel, P., Nogueira, R. G., Parsons, M. W., Sasaki, M., Wardlaw, J. M., Wu, O., Zhang, W., Zhu, G. & Warach, S. J., Jul 2015, In: International Journal of Stroke. 10, 5, p. 759-62 4 p.

    Research output: Contribution to journalArticlepeer-review

  304. Effect of intravenous recombinant tissue-type plasminogen activator in patients with mild stroke in the Third International Stroke Trial-3: post hoc analysis

    Khatri, P., Tayama, D., Cohen, G., Lindley, R., Wardlaw, J., Yeatts, SD., Broderick, JP. & Sandercock, P., 23 Jun 2015, In: Stroke.

    Research output: Contribution to journalArticlepeer-review

  305. What are white matter hyperintensities made of? Relevance to vascular cognitive impairment

    Wardlaw, J., Valdes Hernandez, M. & Munoz-Maniega, S., 23 Jun 2015, In: Journal of the American Heart Association Cardiovascular and Cerebrovascular Disease. 4, p. 001140

    Research output: Contribution to journalArticlepeer-review

  306. Coupled changes in brain white matter microstructure and fluid intelligence in later life

    Ritchie, S. J., Bastin, M. E., Tucker-Drob, E. M., Munoz-Maniega, S., Engelhardt, L. E., Cox, S. R., Royle, N. A., Gow, A. J., Corley, J., Pattie, A., Taylor, A. M., Valdes Hernandez, M. D. C., Starr, J. M., Wardlaw, J. M. & Deary, I., 3 Jun 2015, In: The Journal of Neuroscience. 35, 22, p. 8672-8682 11 p.

    Research output: Contribution to journalArticlepeer-review

  307. Hippocampal shape modeling based on a progressive template surface deformation and its verification

    Kim, J., Valdes Hernandez, M., Royle, N., Park, J., The Lothian Birth Cohort 1936 Collaborative Group & The Alzheimer’s Disease Neuroimaging Initiative, Jun 2015, In: IEEE Transactions on Medical Imaging. 99

    Research output: Contribution to journalArticlepeer-review

  308. HydroCoils Reduce Recurrence Rates in Recently Ruptured Medium-Sized Intracranial Aneurysms: A Subgroup Analysis of the HELPS Trial

    Brinjikji, W., White, P. M., Nahser, H., Wardlaw, J., Sellar, R., Cloft, H. J., Kallmes, D. F. & Sellar, R., Jun 2015, In: American Journal of Neuroradiology. 36, 6

    Research output: Contribution to journalArticle

  309. Pharmacological treatment and prevention of cerebral small vessel disease: a review of potential interventions

    Bath, P. M. W. & Wardlaw, J., Jun 2015, In: International Journal of Stroke. 10, 4, p. 469–478

    Research output: Contribution to journalLiterature reviewpeer-review

  310. Proton spectroscopic imaging of brain metabolites in basal ganglia of healthy older adults

    Parikh, J., Thrippleton, M., Murray, C., Armitage, P., Harris, BA., Andrews, P., Wardlaw, J., Starr, J., Deary, I. & Marshall, I., Jun 2015, In: Magnetic Resonance Materials in Physics, Biology and Medicine. 28, 3, p. 251-257

    Research output: Contribution to journalArticlepeer-review

  311. Use of brain MRI atlases to determine boundaries of age-related pathology: the importance of statistical method

    Dickie, D., Job, D., Rodriguez, D., Shenkin, S. & Wardlaw, J., 29 May 2015, In: PLoS ONE. 10, 5, e0127939.

    Research output: Contribution to journalArticlepeer-review

  312. Association between brain imaging signs, early and late outcomes, and response to intravenous alteplase after acute ischaemic stroke in the third International Stroke Trial (IST-3): secondary analysis of a randomised controlled trial

    The IST-3 Collaborative Group , 1 May 2015, In: Lancet Neurology. 14, 5, p. 485-496 12 p.

    Research output: Contribution to journalArticlepeer-review

  313. Intelligence in childhood and atherosclerosis of the carotid and peripheral arteries in later life: The Lothian Birth Cohort 1936

    Gale, C., Eadie, E., Thomas, A., Bastin, M., Starr, J., Wardlaw, J. & Deary, I., 27 Apr 2015, In: PLoS ONE. 10, 4, 7 p., e0125280.

    Research output: Contribution to journalArticlepeer-review

  314. Common genetic variants influence human subcortical brain structures

    Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 272 others, Cuellar-Partida, G., den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., Macare, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santianez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., van Donkelaar, M. M. J., van Eijk, K. R., Walters, R. K., Westlye, L. T., Whelan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R. R., Matarin, M., Naber, M. A. M., McKay, D. R., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., Marel, S. S. L. V. D., van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., de Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T. M., Fox, P. T., Fukunaga, M., Gibbs, J. R., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J-J., Ikeda, M., Jack Jr, C. R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent Jr, J. W., Kochunov, P. V., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Pike, G. B., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Valdés Hernández, M. C., van 't Ent, D., van der Brug, M., van der Wee, N. J. A., van Tol, M-J., Veltman, D. J., Wassink, T. H., Westman, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B-C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, S. M., Smoller, J. W., van Bokhoven, H., Van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., Geus, E. J. C. D., Deary, I. J., Donohoe, G., Fernández, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Pol, H. E. H., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V. S., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A. J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D. R., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., van der Lee, S. J., Ebling, M., Fischl, B., Longstreth Jr, W. T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L. N., Duijn, C. M. V., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Ikram, M. A., The Alzheimer’s Disease Neuroimaging Initiative, CHARGE Consortium, EPIGEN Consortium, IMAGEN Consortium, SYS, Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., 9 Apr 2015, In: Nature. 520, 7546, p. 224-229 6 p.

    Research output: Contribution to journalArticlepeer-review

  315. Cochrane reviewers’ response to Alper and colleagues’ analysis of thrombolysis in acute ischaemic stroke

    Wardlaw, J. & Berge, E., 7 Apr 2015, In: British Medical Journal (BMJ). 350, p. h1790

    Research output: Contribution to journalLetterpeer-review

  316. Cerebral lesions on 7 Tesla MRI in patients with sickle cell anemia

    van der Land, V., Zwaneburg, JJ., Fijnvandraat, K., Biemond, BJ., Hendrikse, J., Mutsaerts, HJ., Visser, F., Wardlaw, J., Nederveen, AJ., Majoie, CB. & Nederkoorn, P. J., Apr 2015, In: Cerebrovascular diseases. 39, p. 181-189

    Research output: Contribution to journalArticlepeer-review

  317. Cerebral perivascular spaces visible on magnetic resonance imaging: Development of a qualitative rating scale and its observer reliability

    Potter, G., Chappell, F., Morris, Z. & Wardlaw, J., Apr 2015, In: Cerebrovascular diseases. 39, p. 224-231

    Research output: Contribution to journalArticlepeer-review

  318. Enlarged perivascular spaces and cerebral small vessel disease

    Potter, G. M., Doubal, F. N., Jackson, C., Chappell, F. M., Sudlow, C., Dennis, M. S. & Wardlaw, J. M., Apr 2015, In: International Journal of Stroke. 10, 3, p. 376-381

    Research output: Contribution to journalArticlepeer-review

  319. Multi-Ethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI

    Verhaaren, B. F. J., Debette, S., Bis, J. C., Smith, J. A., Ikram, M. K., Adams, H. H., Beecham, A. H., Rajan, K. B., Lopez, L. M., Barral, S., van Buchem, M. A., van der Grond, J., Smith, A. V., Hegenscheid, K., Aggarwal, N. T., de Andrade, M., Atkinson, E. J., Beekman, M., Beiser, A. S., Blanton, S. H. & 82 others, Boerwinkle, E., Brickman, A. M., Bryan, R. N., Chauhan, G., Chen, C. P. L. H., Chouraki, V., de Craen, A. J. M., Crivello, F., Deary, I. J., Deelen, J., De Jager, P. L., Dufouil, C., Elkind, M. S. V., Evans, D. A., Freudenberger, P., Gottesman, R. F., Guðnason, V., Habes, M., Heckbert, S. R., Heiss, G., Hilal, S., Hofer, E., Hofman, A., Ibrahim-Verbaas, C. A., Knopman, D. S., Lewis, C. E., Liao, J., Liewald, D. C. M., Luciano, M., van der Lugt, A., Martinez, O. O., Mayeux, R., Mazoyer, B., Nalls, M. A., Nauck, M., Niessen, W. J., Oostra, B. A., Psaty, B. M., Rice, K. M., Rotter, J. I., von Sarnowski, B., Schmidt, H., Schreiner, P. J., Schuur, M., Sidney, S. S., Sigurdsson, S., Slagboom, P. E., Stott, D. J. M., van Swieten, J. C., Teumer, A., Töglhofer, A. M., Traylor, M., Trompet, S., Turner, S. T., Tzourio, C., Uh, H-W., Uitterlinden, A. G., Vernooij, M. W., Wang, J. J., Wong, T. Y., Wardlaw, J. M., Windham, B. G., Wittfeld, K., Wolf, C., Wright, C. B., Yang, Q., Zhao, W., Zijdenbos, A., Jukema, J. W., Sacco, R. L., Kardia, S. L. R., Amouyel, P., Mosley, T. H., Longstreth, W. T., DeCarli, C. C., van Duijn, C. M., Schmidt, R., Launer, L. J., Grabe, H. J., Seshadri, S. S., Ikram, M. A. & Fornage, M., Apr 2015, In: Circulation: Cardiovascular Genetics. 8, 2, p. 398-+ 54 p.

    Research output: Contribution to journalArticlepeer-review

  320. Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data

    Kochunov, P., Jahanshad, N., Marcus, D., Winkler, A., Sprooten, E., Nichols, T. E., Wright, S. N., Hong, L. E., Patel, B., Behrens, T., Jbabdi, S., Andersson, J., Lenglet, C., Yacoub, E., Moeller, S., Auerbach, E., Ugurbil, K., Sotiropoulos, S. N., Brouwer, R. M., Landman, B. & 33 others, Lemaitre, H., den Braber, A., Zwiers, M. P., Ritchie, S., van Hulzen, K., Almasy, L., Curran, J., deZubicaray, G. I., Duggirala, R., Fox, P., Martin, N. G., McMahon, K. L., Mitchell, B., Olvera, R. L., Peterson, C., Starr, J., Sussmann, J., Wardlaw, J., Wright, M., Boomsma, D. I., Kahn, R., de Geus, E. J. C., Williamson, D. E., Hariri, A., van 't Ent, D., Bastin, M. E., McIntosh, A., Deary, I. J., Hulshoff Pol, H. E., Blangero, J., Thompson, P. M., Glahn, D. C. & Van Essen, D. C., 4 Mar 2015, In: NeuroImage. 111, p. 300-311 12 p.

    Research output: Contribution to journalArticlepeer-review

  321. Alteplase for Acute Ischemic Stroke: Outcomes by Clinically Important Subgroups in the Third International Stroke Trial

    Lindley, R. I., Wardlaw, J. M., Whiteley, W. N., Cohen, G., Blackwell, L., Murray, G. D., Sandercock, P. A. G., on behalf of the IST-3 Collaborative Group, Sellar, R. & Farrall, A., Mar 2015, In: Stroke. 46, 3, p. 746-756 11 p.

    Research output: Contribution to journalArticlepeer-review

  322. Association of allostatic load with brain structure and cognitive ability in later life

    Booth, T., Royle, N. A., Corley, J., Gow, A. J., Valdés Hernández, M. D. C., Munoz-Maniega, S., Ritchie, S. J., Bastin, M. E., Starr, J. M., Wardlaw, J. M. & Deary, I. J., Mar 2015, In: Neurobiology of Aging. 36, 3, p. 1390-1399 10 p.

    Research output: Contribution to journalArticlepeer-review

  323. White matter hyperintensities and normal-appearing white matter integrity in the aging brain

    Muñoz Maniega, S., Valdés Hernández, M. C., Clayden, J. D., Royle, N. A., Murray, C., Morris, Z., Aribisala, B. S., Gow, A. J., Starr, J. M., Bastin, M. E., Deary, I. J. & Wardlaw, J. M., 28 Feb 2015, In: Neurobiology of Aging. 36, 2, p. 909-918 9 p.

    Research output: Contribution to journalArticlepeer-review

  324. Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease

    Holland, P., Searcy, L., Salvadores, N., Scullion, G., Chen, G., Lawson, G., Scott, F., Bastin, M., Ihara, M., Kalaria, R. N., Wood, E., Smith, C., Wardlaw, J. & Horsburgh, K., 21 Feb 2015, In: Journal of Cerebral Blood Flow and Metabolism. 35, 6, p. 1005-1014

    Research output: Contribution to journalArticlepeer-review

  325. Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): A partial-factorial randomised controlled trial

    ENOS Trial Investigators, 14 Feb 2015, In: The Lancet. 385, 9968, p. 617-628 12 p.

    Research output: Contribution to journalArticlepeer-review

  326. Cigarette smoking and thinning of the brain's cortex

    Karama, S., Ducharme, S., Corley, J., Chouinard-Decorte, F., Starr, J., Wardlaw, J., Bastin, M. & Deary, I., 10 Feb 2015, In: Molecular Psychiatry. 20, p. 778–785

    Research output: Contribution to journalArticlepeer-review

  327. Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats

    Holland, P. R., Pannozzo, M. A., Bastin, M. E., McNeilly, A. D., Ferguson, K. J., Caughey, S., Jansen, M. A., Merrifield, G. D., Marshall, I., Mullins, J. J., Wardlaw, J. M., Sutherland, C. & Horsburgh, K., Feb 2015, In: Journal of Cerebral Blood Flow and Metabolism. 35, p. 188-192

    Research output: Contribution to journalArticlepeer-review

  328. Automated segmentation of multifocal basal ganglia T2*-weighted MRI hypointensities

    Glatz, A., Bastin, M., Kiker, AJ., Deary, I., Wardlaw, J. & Hernandez, M. D. C. V., 15 Jan 2015, In: NeuroImage. 105, p. 332-346 15 p.

    Research output: Contribution to journalArticlepeer-review

  329. Influence of Intracerebral Hemorrhage Location on Incidence, Characteristics, and Outcome: Population-Based Study

    Samarasekera, N., Fonville, A., Lerpiniere, C., Farrall, A. J., Wardlaw, J. M., White, P. M., Smith, C., Al-Shahi Salman, R. & for the Lothian Audit of the Treatment of Cerebral Haemorrhage Collaborators, 13 Jan 2015, In: Stroke. 46, p. 361-368

    Research output: Contribution to journalArticlepeer-review

  330. Performance characteristics of methods for quantifying spontaneous intracerebral haemorrhage: data from the Efficacy of Nitric Oxide in Stroke (ENOS) trial

    Krishnan, K., Mukhtar, S. F., Lingard, J., Houlton, A., Walker, E., Jones, T., Sprigg, N., Dineen, R. A., Koumellis, P., Adami, A., Casado, A., Bath, P. M. W. & Wardlaw, J., 9 Jan 2015, In: Journal of Neurology, Neurosurgery & Psychiatry. 86, p. 1258-1266

    Research output: Contribution to journalArticlepeer-review

  331. Exploratory analysis of dietary intake and brain iron accumulation detected using magnetic resonance imaging in older individuals: the Lothian Birth Cohort 1936

    Valdes Hernandez, M., Allan, J., Glatz, A., Kyle, J., Corley, J., Brett, C., Munoz-Maniega, S., Royle, N., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., Jan 2015, In: Journal of Nutrition, Health and Aging. 19, 1, p. 64-69

    Research output: Contribution to journalArticlepeer-review

  332. Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial

    The IST-3 Collaborative Group , Jan 2015, In: Neuroradiology. 57, 1, p. 1-9 9 p.

    Research output: Contribution to journalArticlepeer-review

  333. Sensitivity and specificity of the Hyperdense Artery Sign for arterial obstruction in acute ischemic stroke

    Mair, G., Boyd, E., Chappell, F., von Kummer, R., Lindley, R., Sandercock, P., Wardlaw, J. & IST-3 Collaborative Group, Jan 2015, In: Stroke. 46, 1, p. 102-107 6 p.

    Research output: Contribution to journalArticlepeer-review

  334. A comparison of location of acute symptomatic versus 'silent' small vessel lesions

    Valdes Hernandez, M., Maconick, L. C., Munoz-Maniega, S., Wang, X., Wiseman, S., Armitage, P., Doubal, F., Makin, S., Sudlow, C., Dennis, M., Deary, I., Bastin, M. & Wardlaw, J., 2015, In: International Journal of Stroke. 10, p. 1044–1050

    Research output: Contribution to journalArticlepeer-review

  335. Brain white matter integrity and cortisol in older men: the Lothian Birth Cohort 1936

    Cox, S. R., Bastin, M. E., Ferguson, K. J., Munoz-Maniega, S., MacPherson, S. E., Deary, I. J., Wardlaw, J. M. & MacLullich, A. M. J., 2015, In: Neurobiology of Aging. 36, 1, p. 257-264 8 p.

    Research output: Contribution to journalArticlepeer-review

  336. Genes from a translational analysis support a multifactorial nature of white matter hyperintensities

    Lopez, L., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz-Maniega, S., Bastin, M., Bailey, E. L., Smith, C., McBride, M. W., Mcclure, J. D., Graham, D., Dominiczak, A. F., Yang, Q., Fornage, M., Ikfram, MA., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S. & 4 others, Porteous, D., Starr, J., Deary, I. & Wardlaw, J., 2015, In: Stroke. 46, 2, p. 341-347 7 p.

    Research output: Contribution to journalArticlepeer-review

  337. Intracranial carotid calcification on cranial computed tomography: visual scoring methods, semiautomated scores, and volume measurements in patients with stroke

    Subedi, D., Zishan, U. M., Chappell, F., Gregoriades, M. L., Sudlow, C., Sellar, R. & Wardlaw, J., 2015, In: Stroke. 46, p. 2504-2509

    Research output: Contribution to journalArticlepeer-review

  338. Neural mechanisms of Trail Making Test performance

    MacPherson, S. E., Cox, S., Aribisala, B., Bastin, M., Wardlaw, J. & Deary, I., 2015, (Unpublished).

    Research output: Contribution to conferencePaperpeer-review

  339. Structural brain MRI trait polygenic score prediction of cognitive abilities

    Generation Scotland & SINAPSE Collaborative Grp, 2015, In: Twin Research and Human Genetics. 18, p. 738-745 8 p.

    Research output: Contribution to journalArticlepeer-review

  340. Textural Characterization on Regions of Interest: A Useful Tool for the Study of Small Vessel Disease

    Viksne, L., Valdes Hernandez, M., Hoban, K., Heye, A. K., Gonzalez-Castro, V. & Wardlaw, J., 2015, Proceedings of the 19th Conference on Medical Image Understanding and Analysis. p. 66-71 6 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  341. Thrombectomy for acute ischaemic stroke

    Wardlaw, J. & Dennis, M., 2015, In: JAMA: the Journal of the American Medical Association. 314, p. 1803-1805

    Research output: Contribution to journalEditorialpeer-review

  342. 2014
  343. Cerebral small vessel disease and renal function: systematic review and meta-analysis

    Makin, S., Cook, F. A. B., Dennis, M. & Wardlaw, J., 24 Dec 2014, In: Cerebrovascular diseases. 39, 1, p. 39-52

    Research output: Contribution to journalArticlepeer-review

  344. Recommendations From the International Stroke Genetics Consortium, Part 1: Standardized Phenotypic Data Collection

    Majersik, J. J., Cole, J. W., Golledge, J., Rost, N. S., Chan, Y-F. Y., Gurol, M. E., Lindgren, A. G., Woo, D., Fernandez-Cadenas, I., Chen, D. T., Thijs, V., Worrall, B. B., Kamal, A., Bentley, P., Wardlaw, J. M., Ruigrok, Y. M., Battey, T. W. K., Schmidt, R., Montaner, J., Giese, A-K. & 8 others, Roquer, J., Jiménez-Conde, J., Lee, C., Ay, H., Martin, J. J., Rosand, J., Maguire, J. & on behalf of the International Stroke Genetics Consortium, 9 Dec 2014, In: Stroke; a journal of cerebral circulation. 46, p. 279-84

    Research output: Contribution to journalArticlepeer-review

  345. Effect of Alteplase Within 6 Hours of Acute Ischemic Stroke on All-Cause Mortality (Third International Stroke Trial)

    Whiteley, W. N., Thompson, D., Murray, G., Cohen, G., Lindley, R. I., Wardlaw, J., Sandercock, P. & IST-3 Collaborative Grp, Dec 2014, In: Stroke. 45, 12, p. 3612-3617 6 p.

    Research output: Contribution to journalArticlepeer-review

  346. Personality, Health, and Brain Integrity: The Lothian Birth Cohort Study 1936

    Booth, T., Mõttus, R., Corley, J., Gow, A. J., Henderson, R. D., Munoz-Maniega, S., Murray, C., Royle, N. A., Sprooten, E., Hernández, M. C. V., Bastin, M. E., Penke, L., Starr, J. M., Wardlaw, J. M. & Deary, I. J., Dec 2014, In: Health Psychology. 33, 12, p. 1477-1486 10 p.

    Research output: Contribution to journalArticlepeer-review

  347. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: A meta-analysis of individual patient data from randomised trials

    Emberson, J., Lees, K. R., Lyden, P., Blackwell, L., Albers, G., Bluhmki, E., Brott, T., Cohen, G., Davis, S., Donnan, G., Grotta, J., Howard, G., Kaste, M., Koga, M., von Kummer, R., Lansberg, M., Lindley, R. I., Murray, G., Olivot, J. M., Parsons, M. & 11 others, Tilley, B., Toni, D., Toyoda, K., Wahlgren, N., Wardlaw, J., Whiteley, W., Del Zoppo, G. J., Baigent, C., Sandercock, P., Hacke, W. & for the Stroke Thrombolysis Trialists' Collaborative Group, 29 Nov 2014, In: The Lancet. 384, 9958, p. 1929-1935 7 p.

    Research output: Contribution to journalArticlepeer-review

  348. Stroke subtype, vascular risk factors and total MRI brain small vessel disease burden

    Staals, J., Makin, S., Doubal, F., Dennis, M. & Wardlaw, J., 30 Sep 2014, In: Neurology. 83, 14, p. 1228-1234

    Research output: Contribution to journalArticlepeer-review

  349. Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden

    Staals, J., Makin, S. D. J., Doubal, F. N., Dennis, M. S. & Wardlaw, J. M., 30 Sep 2014, In: Neurology. 83, 14, p. 1228-1234 7 p.

    Research output: Contribution to journalArticlepeer-review

  350. Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity?

    Lyall, D. M., Harris, S. E., Bastin, M. E., Munoz-Maniega, S., Murray, C., Lutz, M. W., Saunders, A. M., Roses, A. D., Valdés Hernández, M., Royle, N. A., Starr, J. M., Porteous, D. J., Wardlaw, J. M. & Deary, I. J., 23 Sep 2014, In: Translational Psychiatry. 4, 9, 7 p., e449.

    Research output: Contribution to journalArticlepeer-review

  351. Assessment of blood-brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review

    Heye, A. K., Culling, R. D., Valdes Hernandez, M., Thrippleton, M. J. & Wardlaw, J. M., 10 Sep 2014, In: NeuroImage: Clinical. 6, p. 262–274

    Research output: Contribution to journalArticlepeer-review

  352. Potential effect of skull thickening on the associations between cognition and brain atrophy in ageing

    Aribisala, B. S., Royle, N. A., Valdés Hernández, M. C., Murray, C., Penke, L., Gow, A., Munoz-Maniega, S., Starr, J. M., Bastin, M., Deary, I. & Wardlaw, J., Sep 2014, In: Age and Ageing. 43, 5, p. 712-716 5 p.

    Research output: Contribution to journalArticlepeer-review

  353. Alteplase for ischaemic stroke--responses

    Sandercock, P., Lindley, R., Wardlaw, J. M., Murray, G., Whiteley, W. & Cohen, G., 23 Aug 2014, In: The Lancet. 384, 9944, p. 660-1 2 p.

    Research output: Contribution to journalArticlepeer-review

  354. Baseline characteristics of the 4011 patients recruited into the 'Efficacy of Nitric Oxide in Stroke' (ENOS) trial

    Bath, P. M. W., Adami, A., Bereczki, D., Berge, E., Beridze, M., Cala, L., Casado, A., Caso, V., Chang, H. M., Christensen, H., Collins, R., Czlonkowska, A., Dineen, R. A., El Etribi, A., Ghani, A. R., Gommans, J., Koumellis, P., Laska, A. C., Lees, K. R., Navarro, J. & 17 others, Ntaios, G., Ozturk, S., Phillips, S., Pocock, S., Prasad, K., Scutt, P., de Silva, H. A., Szatmari, S., Diez-Tejedor, E., Utton, S., Wang, Y-J., Wardlaw, J. M., Whynes, D., Wong, L., Woodhouse, L., Sprigg, N. & ENOS Investigators, Aug 2014, In: International Journal of Stroke. 9, 6, p. 711-720 10 p.

    Research output: Contribution to journalArticlepeer-review

  355. Imaging of acute stroke prior to treatment: current practice and evolving techniques

    Mair, G. & Wardlaw, J., Aug 2014, In: British Journal of Radiology. 87, 1040, 14 p., 20140216.

    Research output: Contribution to journalLiterature reviewpeer-review

  356. Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling

    Kochunov, P., Jahanshad, N., Sprooten, E., Nichols, T. E., Mandl, R. C., Almasy, L., Booth, T., Brouwer, R. M., Curran, J. E., de Zubicaray, G. I., Dimitrova, R., Duggirala, R., Fox, P. T., Elliot Hong, L., Landman, B. A., Lemaitre, H., Lopez, L., Martin, N. G., McMahon, K. L., Mitchell, B. D. & 21 others, Olvera, R. L., Peterson, C. P., Starr, J. M., Sussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Wright, S. N., Bastin, M. E., McIntosh, A. M., Boomsma, D. I., Kahn, R. S., den Braber, A., de Geus, E. J. C., Deary, I. J., Hulshoff Pol, H. E., Williamson, D. E., Blangero, J., van 't Ent, D., Thompson, P. M. & Glahn, D. C., 15 Jul 2014, In: NeuroImage. 95, p. 136-150 15 p.

    Research output: Contribution to journalArticlepeer-review

  357. EuroHYP-1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke

    van der Worp, H. B., Macleod, M. R., Bath, P. M. W., Demotes, J., Durand-Zaleski, I., Gebhardt, B., Gluud, C., Kollmar, R., Krieger, D. W., Lees, K. R., Molina, C., Montaner, J., Roine, R. O., Petersson, J., Staykov, D., Szabo, I., Wardlaw, J. M., Schwab, S. & EuroHYP-1 Investigators, Jul 2014, In: International Journal of Stroke. 9, 5, p. 642-645 4 p.

    Research output: Contribution to journalArticlepeer-review

  358. How normal is this brain? A new nonparametric voxel-based method of comparing brain scans to age-appropriate reference templates

    Dickie, D. A., Job, D. E., Rodriguez-gonzalez, D., Shenkin, S. D. & Wardlaw, J. M., 1 Jun 2014, In: Age and Ageing. 43, suppl 1, p. i32

    Research output: Contribution to journalArticlepeer-review

  359. Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936

    Lyall, D. M., Harris, S. E., Bastin, M. E., Munoz-Maniega, S., Murray, C., Lutz, M. W., Saunders, A. M., Roses, A. D., Hernandez, M. D. C. V., Royle, N. A., Starr, J. M., Porteous, D. J., Wardlaw, J. M. & Deary, I. J., Jun 2014, In: Neurobiology of Aging. 35, 6, p. 1513.e25–1513.e33 9 p.

    Research output: Contribution to journalArticlepeer-review

  360. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

    Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., Franke, B., Wright, M. J., Martin, N. G., Agartz, I., Alda, M., Alhusaini, S., Almasy, L., Almeida, J., Alpert, K., Andreasen, N. C., Andreassen, O. A. & 34 others, Apostolova, L. G., Appel, K., Armstrong, N. J., Aribisala, B., Bastin, M. E., Bauer, M., Bearden, C. E., Bergmann, O., Binder, E. B., Blangero, J., Bockholt, H. J., Boen, E., Bois, C., Boomsma, D. I., Booth, T., Bowman, I. J., Bralten, J., Deary, I. J., Hall, J., Lawrie, S. M., Liewald, D. C., Lopez, L. M., Luciano, M., McIntosh, A. M., Royle, N. A., Smith, C., Starr, J. M., Sussmann, J., Wardlaw, J. M., Whalley, H. C., Alzheimer's Dis Neuroimaging, EPIGEN Consortium, IMAGEN Consortium & Saguenay Youth Study SYS Grp, Jun 2014, In: Brain imaging and behavior. 8, 2, p. 153-182 30 p.

    Research output: Contribution to journalArticlepeer-review

  361. Childhood cognitive ability accounts for associations between cognitive ability and brain cortical thickness in old age

    Karama, S., Bastin, M. E., Murray, C., Royle, N. A., Penke, L., Munoz-Maniega, S., Gow, A. J., Corley, J., Valdés Hernández, M., Lewis, J. D., Rousseau, M-E., Lepage, C., Fonov, V., Collins, D. L., Booth, T., Rioux, P., Sherif, T., Adalat, R., Starr, J. M., Evans, A. C. & 2 others, Wardlaw, J. M. & Deary, I. J., May 2014, In: Molecular Psychiatry. 19, 5, p. 555-559 5 p.

    Research output: Contribution to journalArticlepeer-review

  362. Corrigendum to Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA-DTI working group [NeuroImage 81 (2013) 455-469]

    Jahanshad, N., Kochunov, P. V., Sprooten, E., Mandl, R. C., Nichols, T. E., Almasy, L., Blangero, J., Brouwer, R. M., Curran, J. E., de Zubicaray, G. I., Duggirala, R., Fox, P. T., Hong, L. E., Landman, B. A., Martin, N. G., McMahon, K. L., Medland, S. E., Mitchell, B. D., Olvera, R. L., Peterson, C. P. & 11 others, Starr, J. M., Sussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Pol, H. E. H., Bastin, M. E., McIntosh, A. M., Deary, I. J., Thompson, P. M. & Glahn, D. C., 15 Apr 2014, In: NeuroImage. 90, p. 470-471 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  363. An assessment of the cost-effectiveness of magnetic resonance, including diffusion-weighted imaging, in patients with transient ischaemic attack and minor stroke: a systematic review, meta-analysis and economic evaluation

    Wardlaw, J., Brazzelli, M., Miranda, H., Chappell, F., McNamee, P., Scotland, G., Quayyum, Z., Martin, D., Shuler, K., Sandercock, P. & Dennis, M., Apr 2014, In: Health Technology Assessment. 18, 27, p. 1-368, v-vi

    Research output: Contribution to journalArticlepeer-review

  364. Quantitative multi-modal MRI of the hippocampus and cognitive ability in community-dwelling older subjects

    Aribisala, B., Royle, N., Munoz-Maniega, S., Valdes Hernandez, M., Murray, C., Penke, L., Gow, A., Starr, J., Bastin, M., Deary, I. & Wardlaw, J., Apr 2014, In: Cortex. 53C, p. 34-44 11 p.

    Research output: Contribution to journalArticlepeer-review

  365. Statistical analysis plan for the 'Efficacy of Nitric Oxide in Stroke' (ENOS) trial

    Bath, P. M. W., Houlton, A., Woodhouse, L., Sprigg, N., Wardlaw, J., Pocock, S. & ENOS Trialists, Apr 2014, In: International Journal of Stroke. 9, 3, p. 372-374 3 p.

    Research output: Contribution to journalArticlepeer-review

  366. Targeting Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Based on Risk of Intracranial Hemorrhage or Poor Functional Outcome An Analysis of the Third International Stroke Trial

    Whiteley, W. N., Thompson, D., Murray, G., Cohen, G., Lindley, R. I., Wardlaw, J., Sandercock, P. & IST-3 Collaborat Grp, Apr 2014, In: Stroke. 45, 4, p. 1000-1006 7 p.

    Research output: Contribution to journalArticlepeer-review

  367. Blood Pressure, Internal Carotid Artery Flow Parameters, and Age-Related White Matter Hyperintensities

    Aribisala, B., Morris, Z., Eadie, E., Thomas, A., Gow, A., Valdes Hernandez, M., Royle, N., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., 8 Feb 2014, In: Hypertension. 63, 5, p. 1011-1018 8 p.

    Research output: Contribution to journalArticlepeer-review

  368. Reliability of MRSI brain temperature mapping at 1.5 and 3 T

    Thrippleton, M. J., Parikh, J., Harris, B., Hammer, S. J., Semple, S. I. K., Andrews, P. J. D., Wardlaw, J. M. & Marshall, I., Feb 2014, In: NMR in Biomedicine. 27, 2, p. 183-190 8 p.

    Research output: Contribution to journalArticlepeer-review

  369. Diffusion-weighted imaging and diagnosis of transient ischaemic attack

    Brazzelli, M., Chappell, F. M., Miranda, H., Shuler, K., Dennis, M., Sandercock, P. A. G., Muir, K. & Wardlaw, J. M., 31 Jan 2014, In: Annals of Neurology. 75, 1, p. 67-76 10 p.

    Research output: Contribution to journalArticlepeer-review

  370. Combining Meta- and mega-analytic approaches for multi-site diffusion imaging based genetic studies: From the enigma-DTI working group

    Jahanshad, N., Kochunov, P., Nichols, T. E., Sprooten, E., Mandl, R. C., Almasy, L., Brouwer, R. M., Curran, J. E., De Zubicaray, G. I., Dimitrova, R., Fox, P. T., Hong, L. E., Landman, B. A., Lemaitre, H., Lopez, L., Martin, N. G., McMahon, K. L., Mitchell, B. D., Olvera, R. L., Peterson, C. P. & 17 others, Sussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Wright, S. N.,