Edinburgh Research Explorer

Dr Joe Rainger

Roslin Research Fellow

Willingness to take PhD students: Yes

Education/Academic qualification

Doctor of Philosophy (PhD)

Biography

Joe Rainger is a UKRI Future Leaders Fellow (Round 2), Roslin Institute Fellow, and a University of Edinburgh ESAT Fellow. His research group aims to understand the complex processes that underly embryonic tissue fusion processes. Research is focused on fusion of tissues in the developing retina and uses chicken embryology as a key experimental model system. Current focus is placed upon revealing specificities of gene transcription at defined stages of tissue fusion, and revealing the regulatory networks that control these transcriptional responses. This is combined with studies of intra- and inter-cellular molecular interactions and dynamic cell behaviours, and exploring the influence of non-genetic factors that may affect tissue fusion. Use is made of transgenic chicken lines from the National Avian Research Facility (NARF, Roslin Institute) and the development of novel transgenic resources to further our understanding of tissue fusion mechanisms in the eye and other embryonic regions. Collaborations with clinical paediatricians and ophthalmologists are welcome to suport the identification and experimental validation of causative genetic mutations in patients and families affected by a wide range of tissue fusion defects.

Biography

Joe Rainger is a UKRI Future Leaders Fellow (Round 2), Roslin Institute Fellow, and a University of Edinburgh ESAT Fellow. His research group aims to understand the complex processes that underly embryonic tissue fusion processes. Research is focused on fusion of tissues in the developing retina and uses chicken embryology as a key experimental model system. Current focus is placed upon revealing specificities of gene transcription at defined stages of tissue fusion, and revealing the regulatory networks that control these transcriptional responses. This is combined with studies of intra- and inter-cellular molecular interactions and dynamic cell behaviours, and exploring the influence of non-genetic factors that may affect tissue fusion. Use is made of transgenic chicken lines from the National Avian Research Facility (NARF, Roslin Institute) and the development of novel transgenic resources to further our understanding of tissue fusion mechanisms in the eye and other embryonic regions. Collaborations with clinical paediatricians and ophthalmologists are welcome to suport the identification and experimental validation of causative genetic mutations in patients and families affected by a wide range of tissue fusion defects.

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