Edinburgh Research Explorer

Prof John Iredale, DM, FRCP, FMedSci, FRSE

Director of MRC/UoE Centre for Inflammation Research , Visitor: Staff Other UK HEI

  1. 2019
  2. Resolving the fibrotic niche of human liver cirrhosis at single-cell level

    Ramachandran, P., Dobie, R., Wilson-Kanamori, J. R., Dora, E., Henderson, B., Luu, N-T., Portman, J., Matchett, K., Brice, M., MARWICK, JOHN. ALEXANDER., Richard, T., Efremova, M., Vento-Tormo, R., Carragher, N., Kendall, T., Fallowfield, J., Harrison, E., Mole, D., Wigmore, S., Newsome, P. N. & 8 others, Weston, C. J., Iredale, J., Tacke, F., Pollard, J., Ponting, C., Marioni, J. C., Teichmann, S. A. & Henderson, N., 9 Oct 2019, In : Nature.

    Research output: Contribution to journalArticle

  3. 2018
  4. Loss of integrin αvβ8 in murine hepatocytes accelerates liver regeneration

    Greenhalgh, S., Matchett, K., Taylor, R., Huang, K., Li, J. T., Saeteurn, K., Donnelly, M. C., Simpson, E. E. M., Pollack, J. L., Atakilit, A., Simpson, K., Maher, J. J., Iredale, J., Sheppard, D. & Henderson, N., 16 Nov 2018, In : American Journal of Pathology.

    Research output: Contribution to journalArticle

  5. TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence

    Bird, T., Müller, M., Boulter, L., Vincent, D. F., Ridgway, R. A., Lopez-Guadamillas, E., Lu, W-Y., Jamieson, T., Govaere, O., Campbell, A. D., Ferreira Gonzalez, S., Cole, A. M., Hay, T., Simpson, K. J., Clark, W., Hedley, A., Clarke, M., Gentaz, P., Nixon, C., Bryce, S. & 14 others, Kiourtis, C., Sprangers, J., Nibbs, R. J. B., van Rooijen, N., Bartholin, L., McGreal, S. R., Apte, U., Barry, S. T., Iredale, J., Clarke, A. R., Serrano, M., Roskams, T. A., Sansom, O. J. & Forbes, S., 16 Aug 2018, In : Science translational medicine.

    Research output: Contribution to journalArticle

  6. An efficient method to isolate Kupffer cells eliminating endothelial cell contamination and selective bias

    Lynch, R., Hawley, C. A., Pellicoro, A., Bain, C., Iredale, J. & Jenkins, S., 1 Apr 2018, In : Journal of Leukocyte Biology.

    Research output: Contribution to journalArticle

  7. 2017
  8. Detecting Drug-Target Binding in Cells using Fluorescence Activated Cell Sorting Coupled with Mass Spectrometry Analysis

    Wilson, K., Webster, S. P., Iredale, J. P., Zheng, X., Homer, N. Z. M., Pham, N., Auer, M. & Mole, D. J., 18 Dec 2017, In : Methods and Applications in Fluorescence.

    Research output: Contribution to journalArticle

  9. Quantification of ethyl glucuronide, ethyl sulfate, nicotine, and its metabolites in human fetal liver and placenta

    Swortwood, M. J., Bartock, S. H., Scheidweiler, K. B., Shaw, S., Filis, P., Douglas, A., O’shaughnessy, P. J., Soffientini, U., Lucendo-villarin, B., Iredale, J. P., Hay, D., Fowler, P. A. & Huestis, M. A., 7 Nov 2017, In : Forensic Toxicology.

    Research output: Contribution to journalArticle

  10. αv integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis

    Murray, I., Gonzalez, Z. N., Dobie, R., Wallace, R., MacKinnon, A., Smith, J. R., Greenhalgh, S., Thompson, A. L., Conroy, K., Griggs, D., Ruminski, P., Gray, G. A., Singh, M., Campbell, M. A., Kendall, T., Dai, J., LI, Y., Iredale, J., Simpson, H., Huard, J. & 2 others, Peault, B. & Henderson, N., 24 Oct 2017, In : Nature Communications. 8, 1, p. 1118

    Research output: Contribution to journalArticle

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