Edinburgh Research Explorer

Jose Garcia-Perez

Chancellor's Fellow

  1. 2019
  2. LINE-1 Evasion of Epigenetic Repression in Humans

    Sanchez-luque, F. J., Kempen, M. H. C., Gerdes, P., Vargas-landin, D. B., Richardson, S. R., Troskie, R., Jesuadian, J. S., Cheetham, S. W., Carreira, P. E., Salvador-palomeque, C., García-cañadas, M., Muñoz-lopez, M., Sanchez, L., Lundberg, M., Macia, A., Heras, S. R., Brennan, P. M., Lister, R., Garcia-perez, J. L., Ewing, A. D. & 1 others, Faulkner, G. J., 20 Jun 2019, In : Molecular Cell.

    Research output: Contribution to journalArticle

  3. 2018
  4. Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s

    Warkocki, Z., Krawczyk, P. S., Adamska, D., Bijata, K., Garcia-Perez, J. L. & Dziembowski, A., 6 Sep 2018, In : Cell. 174, 6, p. 1537-1548.E29 41 p.

    Research output: Contribution to journalArticle

  5. Impact of non-LTR retrotransposons in the differentiation and evolution of anatomically modern humans

    Guichard, E., Peona, V., Tagliazucchi, G. M., Abitante, L., Jagoda, E., Musella, M., Ricci, M., Rubio-Roldan, A., Sarno, S., Luiselli, D., Pettener, D., Taccioli, C., Pagani, L., Luis Garcia-Perez, J. & Boattini, A., 15 Aug 2018, In : Mobile DNA. 9, 19 p., 28.

    Research output: Contribution to journalArticle

  6. Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins

    Mayer, J., Harz, C., Sanchez, L., Pereira, G. C., Maldener, E., Heras, S. R., Ostrow, L. W., Ravits, J., Batra, R., Meese, E., Luis Garcia-Perez, J. & Goodier, J. L., 2 Aug 2018, In : Molecular Neurodegeneration. 13, 25 p., 39.

    Research output: Contribution to journalArticle

  7. RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition

    Benitez-Guijarro, M., Lopez-Ruiz, C., Tamauskaite, Z., Murina, O., Mohammad, M. M., Williams, T. C., Fluteau, A., Sanchez, L., Vilar-Astasio, R., Garcia-Cañadas, M., Cano, D., Kempen, M-J., Sanchez-Pozo, A., Heras, S. R., Jackson, A. P., Reijns, M. A. M. & Garcia-Perez, J. L., 1 Aug 2018, In : EMBO Journal. 37, 22 p., e98506.

    Research output: Contribution to journalArticle

  8. 2017
  9. L1 Mosaicism in Mammals: Extent, Effects, and Evolution

    Faulkner, G. J. & Garcia-Perez, J. L., 1 Nov 2017, In : Trends in Genetics.

    Research output: Contribution to journalReview article

  10. The TREX1 Dinosaur Bites the Brain through the LINE

    García Pérez, J. L. & Alarcón-Riquelme, M. E., 7 Sep 2017, In : Cell Stem Cell. 21, 3, p. 287-288 2 p.

    Research output: Contribution to journalReview article

  11. Mobilization of LINE-1 Retrotransposons is Restricted by Tex19.1 in Mouse Embryonic Stem Cells

    Maclennan, M., Garcia-Cañadas, M., Reichmann, J., Khazina, E., Wagner, G., Playfoot, C. J., Salvador-Palomeque, C., Mann, A. R., Peressini, P., Sanchez, L., Dobie, K., Read, D., Hung, C-C., Eskeland, R., Meehan, R. R., Weichenrieder, O., García-Pérez, J. L. & Adams, I. R., 14 Aug 2017, In : eLIFE. 6, 32 p., e26152.

    Research output: Contribution to journalArticle

  12. Heritable L1 retrotransposition in the mouse primordial germline and early embryo

    Richardson, S. R., Gerdes, P., Gerhardt, D. J., Sanchez-Luque, F. J., Bodea, G-O., Munoz-Lopez, M., Jesuadian, J. S., Kempen, M-J. H. C., Carreira, P. E., Jeddeloh, J. A., Garcia-Perez, J. L., Kazazian Jr, H. H., Ewing, A. D. & Faulkner, G. J., Aug 2017, In : Genome Research. 27, 8, p. 1395-1405 11 p.

    Research output: Contribution to journalArticle

  13. Engineered LINE-1 retrotransposition in nondividing human neurons

    Macia, A., Widmann, T. J., Heras, S. R., Ayllon, V., Sanchez, L., Benkaddour-Boumzaouad, M., Muñoz-Lopez, M., Rubio, A., Amador-Cubero, S., Blanco-Jimenez, E., Garcia-Castro, J., Menendez, P., Ng, P., Muotri, A. R., Goodier, J. L. & Garcia-Perez, J. L., Mar 2017, In : Genome Research. 27, 3, p. 335-348 14 p.

    Research output: Contribution to journalArticle

  14. 2016
  15. The impact of transposable elements on mammalian development

    Garcia-Perez, J. L., Widmann, T. J. & Adams, I. R., 15 Nov 2016, In : Development. 143, 22, p. 4101-4114 14 p.

    Research output: Contribution to journalReview article

  16. Characterization of Engineered L1 Retrotransposition Events: The Recovery Method

    Cano, D., Morell, S., Pulgarin, A. J., Amador, S. & Garcia-Pérez, J. L., 20 Feb 2016, Transposons and Retrotransposons. Springer, Vol. 1400. p. 165-82 18 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  17. Study of Transposable Elements and Their Genomic Impact

    Muñoz-Lopez, M., Vilar-Astasio, R., Tristan-Ramos, P., Lopez-Ruiz, C. & Garcia-Pérez, J. L., 20 Feb 2016, Transposons and Retrotransposons. Springer, Vol. 1400. p. 1-19 19 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  18. Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor

    Morales-Hernández, A., González-Rico, F. J., Román, A. C., Rico-Leo, E., Alvarez-Barrientos, A., Sánchez, L., Macia, Á., Heras, S. R., García-Pérez, J. L., Merino, J. M. & Fernández-Salguero, P. M., 15 Feb 2016, In : Nucleic Acids Research.

    Research output: Contribution to journalArticle

  19. Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells

    Klawitter, S., Fuchs, N. V., Upton, K. R., Muñoz-Lopez, M., Shukla, R., Wang, J., Garcia-Cañadas, M., Lopez-Ruiz, C., Gerhardt, D. J., Sebe, A., Grabundzija, I., Merkert, S., Gerdes, P., Pulgarin, J. A., Bock, A., Held, U., Witthuhn, A., Haase, A., Sarkadi, B., Löwer, J. & 7 others, Wolvetang, E. J., Martin, U., Ivics, Z., Izsvák, Z., Garcia-Perez, J. L., Faulkner, G. J. & Schumann, G. G., 8 Jan 2016, In : Nature Communications. 7, p. 10286

    Research output: Contribution to journalArticle

  20. 2015
  21. Localization of a bacterial group II intron-encoded protein in human cells

    Reinoso-Colacio, M., García-Rodríguez, F. M., García-Cañadas, M., Amador-Cubero, S., García Pérez, J. L. & Toro, N., 5 Aug 2015, In : Scientific Reports. 5, p. 12716

    Research output: Contribution to journalArticle

  22. Retrotransposons in pluripotent cells: Impact and new roles in cellular plasticity

    Macia, A., Blanco-Jimenez, E. & García-Pérez, J. L., Apr 2015, In : Biochimica et biophysica acta-Bioenergetics. 1849, 4, p. 417-26 10 p.

    Research output: Contribution to journalArticle

  23. The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes

    Richardson, S. R., Doucet, A. J., Kopera, H. C., Moldovan, J. B., Garcia-Perez, J. L. & Moran, J. V., Apr 2015, In : Microbiology Spectrum. 3, 2, p. MDNA3-0061-2014

    Research output: Contribution to journalArticle

  24. 2014
  25. Role of BRD4 in hematopoietic differentiation of embryonic stem cells

    Rodriguez, R. M., Suarez-Alvarez, B., Salvanés, R., Huidobro, C., Toraño, E. G., Garcia-Perez, J., Lopez-Larrea, C., Fernandez, A. F., Bueno, C., Menendez, P. & Fraga, M. F., Apr 2014, In : Epigenetics. 9, 4, p. 566-78 13 p.

    Research output: Contribution to journalArticle

  26. Control of mammalian retrotransposons by cellular RNA processing activities

    Heras, S. R., Macias, S., Cáceres, J. F. & Garcia-Perez, J., 2014, In : Mobile Genetic Elements. 4, p. e28439

    Research output: Contribution to journalArticle

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