Edinburgh Research Explorer

Jose Garcia-Perez

Chancellor's Fellow

  1. Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor

    Morales-Hernández, A., González-Rico, F. J., Román, A. C., Rico-Leo, E., Alvarez-Barrientos, A., Sánchez, L., Macia, Á., Heras, S. R., García-Pérez, J. L., Merino, J. M. & Fernández-Salguero, P. M., 15 Feb 2016, In : Nucleic Acids Research.

    Research output: Contribution to journalArticle

  2. An epi [c] genetic battle: LINE-1 retrotransposons and intragenomic conflict in humans

    Muñoz-Lopez, M., Macia, A., Garcia-Cañadas, M., Badge, R. M. & Garcia-Perez, J. L., Jul 2011, In : Mobile Genetic Elements. 1, 2, p. 122-127 6 p.

    Research output: Contribution to journalArticle

  3. Analysis of LINE-1 expression in human pluripotent cells

    Muñoz-Lopez, M., Garcia-Cañadas, M., Macia, A., Morell, S. & Garcia-Perez, J. L., 2012, In : Methods in Molecular Biology. 873, p. 113-25 13 p.

    Research output: Contribution to journalArticle

  4. Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells

    Coufal, N. G., Garcia-Perez, J. L., Peng, G. E., Marchetto, M. C. N., Muotri, A. R., Mu, Y., Carson, C. T., Macia, A., Moran, J. V. & Gage, F. H., 20 Dec 2011, In : Proceedings of the National Academy of Sciences (PNAS). 108, 51, p. 20382-7 6 p.

    Research output: Contribution to journalArticle

  5. Cellular inhibitors of long interspersed element 1 and Alu retrotransposition

    Bogerd, H. P., Wiegand, H. L., Hulme, A. E., Garcia-Perez, J. L., O'Shea, K. S., Moran, J. V. & Cullen, B. R., 6 Jun 2006, In : Proceedings of the National Academy of Sciences (PNAS). 103, 23, p. 8780-5 6 p.

    Research output: Contribution to journalArticle

  6. Characterization of Engineered L1 Retrotransposition Events: The Recovery Method

    Cano, D., Morell, S., Pulgarin, A. J., Amador, S. & Garcia-Pérez, J. L., 20 Feb 2016, Transposons and Retrotransposons. Springer, Vol. 1400. p. 165-82 18 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

  7. Characterization of reverse transcriptase activity of the L1Tc retroelement from Trypanosoma cruzi

    García-Pérez, J. L., González, C. I., Thomas, M. C., Olivares, M. & López, M. C., Dec 2003, In : Cellular and Molecular Life Sciences. 60, 12, p. 2692-701 10 p.

    Research output: Contribution to journalArticle

  8. Control of mammalian retrotransposons by cellular RNA processing activities

    Heras, S. R., Macias, S., Cáceres, J. F. & Garcia-Perez, J., 2014, In : Mobile Genetic Elements. 4, p. e28439

    Research output: Contribution to journalArticle

  9. DNA transposons: nature and applications in genomics

    Muñoz-López, M. & García-Pérez, J. L., Apr 2010, In : Current Genomics. 11, 2, p. 115-28 14 p.

    Research output: Contribution to journalArticle

  10. Distinct mechanisms for trans-mediated mobilization of cellular RNAs by the LINE-1 reverse transcriptase

    Garcia-Perez, J. L., Doucet, A. J., Bucheton, A., Moran, J. V. & Gilbert, N., May 2007, In : Genome Research. 17, 5, p. 602-11 10 p.

    Research output: Contribution to journalArticle

  11. Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells

    Wissing, S., Montano, M., Garcia-Perez, J. L., Moran, J. V. & Greene, W. C., 21 Oct 2011, In : Journal of Biological Chemistry. 286, 42, p. 36427-37 11 p.

    Research output: Contribution to journalArticle

  12. Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma

    Shukla, R., Upton, K. R., Munoz-Lopez, M., Gerhardt, D. J., Fisher, M. E., Thu Nguyen, N. V., Brennan, P. M., Baillie, J. K., Collino, A., Ghisletti, S., Sinha, S., Iannelli, F., Radaelli, E., Dos Santos, A., Rapoud, D., Guettier, C., Samuel, D., Natoli, G., Carninci, P., Ciccarelli, F. D. & 3 others, Garcia-Perez, J., Faivre, J. & Faulkner, G. J., 28 Mar 2013, In : Cell. 153, 1, p. 101-111 11 p.

    Research output: Contribution to journalArticle

  13. Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres

    Morrish, T. A., Garcia-Perez, J. L., Stamato, T. D., Taccioli, G. E., Sekiguchi, J. & Moran, J. V., 8 Mar 2007, In : Nature. 446, 7132, p. 208-12 5 p.

    Research output: Contribution to journalArticle

  14. Engineered LINE-1 retrotransposition in nondividing human neurons

    Macia, A., Widmann, T. J., Heras, S. R., Ayllon, V., Sanchez, L., Benkaddour-Boumzaouad, M., Muñoz-Lopez, M., Rubio, A., Amador-Cubero, S., Blanco-Jimenez, E., Garcia-Castro, J., Menendez, P., Ng, P., Muotri, A. R., Goodier, J. L. & Garcia-Perez, J. L., Mar 2017, In : Genome Research. 27, 3, p. 335-348 14 p.

    Research output: Contribution to journalArticle

  15. Enhanced transfection efficiency of human embryonic stem cells by the incorporation of DNA liposomes in extracellular matrix

    Villa-Diaz, L. G., Garcia-Perez, J. L. & Krebsbach, P. H., Dec 2010, In : Stem Cells and Development. 19, 12, p. 1949-57 9 p.

    Research output: Contribution to journalArticle

  16. Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease

    Sánchez, L., Gutierrez-Aranda, I., Ligero, G., Rubio, R., Muñoz-López, M., García-Pérez, J. L., Ramos, V., Real, P. J., Bueno, C., Rodríguez, R., Delgado, M. & Menendez, P., Feb 2011, In : Stem Cells. 29, 2, p. 251-62 12 p.

    Research output: Contribution to journalArticle

  17. Epigenetic control of retrotransposon expression in human embryonic stem cells

    Macia, A., Muñoz-Lopez, M., Cortes, J. L., Hastings, R. K., Morell, S., Lucena-Aguilar, G., Marchal, J. A., Badge, R. M. & Garcia-Perez, J. L., Jan 2011, In : Molecular and Cellular Biology. 31, 2, p. 300-16 17 p.

    Research output: Contribution to journalArticle

  18. Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells

    Garcia-Perez, J. L., Morell, M., Scheys, J. O., Kulpa, D. A., Morell, S., Carter, C. C., Hammer, G. D., Collins, K. L., O'Shea, K. S., Menendez, P. & Moran, J. V., 5 Aug 2010, In : Nature. 466, 7307, p. 769-73 5 p.

    Research output: Contribution to journalArticle

  19. Etoposide induces MLL rearrangements and other chromosomal abnormalities in human embryonic stem cells

    Bueno, C., Catalina, P., Melen, G. J., Montes, R., Sánchez, L., Ligero, G., García-Pérez, J. L. & Menendez, P., Sep 2009, In : Carcinogenesis. 30, 9, p. 1628-37 10 p.

    Research output: Contribution to journalArticle

  20. Genomic clustering of the Trypanosoma cruzi nonlong terminal L1Tc retrotransposon with defined interspersed repeated DNA elements

    Olivares, M., del Carmen Thomas, M., López-Barajas, A., Requena, J. M., García-Pérez, J. L., Angel, S., Alonso, C. & López, M. C., Aug 2000, In : Electrophoresis. 21, 14, p. 2973-82 10 p.

    Research output: Contribution to journalArticle

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