Edinburgh Research Explorer

Dr Jose Garcia-Perez

Chancellor's Fellow

  1. iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability

    Ramos-Mejia, V., Muñoz-Lopez, M., Garcia-Perez, J. L. & Menendez, P., Oct 2010, In : Cell Research . 20, 10, p. 1092-5 4 p.

    Research output: Contribution to journalArticle

  2. Wiping DNA methylation: Wip1 regulates genomic fluidity on cancer

    Muñoz-Lopez, M., Medina, P. P. & Garcia-Perez, J. L., 14 Oct 2013, In : Cancer cell. 24, 4, p. 405-7 3 p.

    Research output: Contribution to journalArticle

  3. Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s

    Warkocki, Z., Krawczyk, P. S., Adamska, D., Bijata, K., Garcia-Perez, J. L. & Dziembowski, A., 6 Sep 2018, In : Cell. 174, 6, p. 1537-+ 41 p.

    Research output: Contribution to journalArticle

  4. Unconventional translation of mammalian LINE-1 retrotransposons

    Alisch, R. S., Garcia-Perez, J. L., Muotri, A. R., Gage, F. H. & Moran, J. V., 15 Jan 2006, In : Genes & Development. 20, 2, p. 210-24 15 p.

    Research output: Contribution to journalArticle

  5. Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins

    Mayer, J., Harz, C., Sanchez, L., Pereira, G. C., Maldener, E., Heras, S. R., Ostrow, L. W., Ravits, J., Batra, R., Meese, E., Luis Garcia-Perez, J. & Goodier, J. L., 2 Aug 2018, In : Molecular Neurodegeneration. 13, 25 p., 39.

    Research output: Contribution to journalArticle

  6. The non-LTR (long terminal repeat) retrotransposon L1Tc from Trypanosoma cruzi codes for a protein with RNase H activity

    Olivares, M., García-Pérez, J. L., Thomas, M. C., Heras, S. R. & López, M. C., 2 Aug 2002, In : Journal of Biological Chemistry. 277, 31, p. 28025-30 6 p.

    Research output: Contribution to journalArticle

  7. The impact of transposable elements on mammalian development

    Garcia-Perez, J. L., Widmann, T. J. & Adams, I. R., 15 Nov 2016, In : Development. 143, 22, p. 4101-4114 14 p.

    Research output: Contribution to journalReview article

  8. The endonuclease NL1Tc encoded by the LINE L1Tc from Trypanosoma cruzi protects parasites from daunorubicin DNA damage

    Olivares, M., López, M. C., García-Pérez, J. L., Briones, P., Pulgar, M. & Thomas, M. C., 15 Apr 2003, In : Biochimica et biophysica acta-Bioenergetics. 1626, 1-3, p. 25-32 8 p.

    Research output: Contribution to journalArticle

  9. The TREX1 Dinosaur Bites the Brain through the LINE

    García Pérez, J. L. & Alarcón-Riquelme, M. E., 7 Sep 2017, In : Cell Stem Cell. 21, 3, p. 287-288 2 p.

    Research output: Contribution to journalReview article

  10. The Microprocessor controls the activity of mammalian retrotransposons

    Heras, S. R., Macias, S., Plass, M., Fernandez, N., Cano, D., Eyras, E., Garcia-Perez, J. & Cáceres, J. F., Oct 2013, In : Nature Structural & Molecular Biology. 20, 10, p. 1173-1181 9 p.

    Research output: Contribution to journalArticle

  11. The L1Tc C-terminal domain from Trypanosoma cruzi non-long terminal repeat retrotransposon codes for a protein that bears two C2H2 zinc finger motifs and is endowed with nucleic acid chaperone activity

    Heras, S. R., López, M. C., García-Pérez, J. L., Martin, S. L. & Thomas, M. C., Nov 2005, In : Molecular and Cellular Biology. 25, 21, p. 9209-20 12 p.

    Research output: Contribution to journalArticle

  12. The Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes

    Richardson, S. R., Doucet, A. J., Kopera, H. C., Moldovan, J. B., Garcia-Perez, J. L. & Moran, J. V., Apr 2015, In : Microbiology Spectrum. 3, 2, p. MDNA3-0061-2014

    Research output: Contribution to journalArticle

  13. Study of Transposable Elements and Their Genomic Impact

    Muñoz-Lopez, M., Vilar-Astasio, R., Tristan-Ramos, P., Lopez-Ruiz, C. & Garcia-Pérez, J. L., 20 Feb 2016, Transposons and Retrotransposons. Springer, Vol. 1400. p. 1-19 19 p. (Methods in Molecular Biology).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  14. Similarities between long interspersed element-1 (LINE-1) reverse transcriptase and telomerase

    Kopera, H. C., Moldovan, J. B., Morrish, T. A., Garcia-Perez, J. L. & Moran, J. V., 20 Dec 2011, In : Proceedings of the National Academy of Sciences. 108, 51, p. 20345-50 6 p.

    Research output: Contribution to journalArticle

  15. Role of BRD4 in hematopoietic differentiation of embryonic stem cells

    Rodriguez, R. M., Suarez-Alvarez, B., Salvanés, R., Huidobro, C., Toraño, E. G., Garcia-Perez, J., Lopez-Larrea, C., Fernandez, A. F., Bueno, C., Menendez, P. & Fraga, M. F., Apr 2014, In : Epigenetics. 9, 4, p. 566-78 13 p.

    Research output: Contribution to journalArticle

  16. Retrotransposons in pluripotent cells: Impact and new roles in cellular plasticity

    Macia, A., Blanco-Jimenez, E. & García-Pérez, J. L., Apr 2015, In : Biochimica et biophysica acta-Bioenergetics. 1849, 4, p. 417-26 10 p.

    Research output: Contribution to journalArticle

  17. Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells

    Klawitter, S., Fuchs, N. V., Upton, K. R., Muñoz-Lopez, M., Shukla, R., Wang, J., Garcia-Cañadas, M., Lopez-Ruiz, C., Gerhardt, D. J., Sebe, A., Grabundzija, I., Merkert, S., Gerdes, P., Pulgarin, J. A., Bock, A., Held, U., Witthuhn, A., Haase, A., Sarkadi, B., Löwer, J. & 7 others, Wolvetang, E. J., Martin, U., Ivics, Z., Izsvák, Z., Garcia-Perez, J. L., Faulkner, G. J. & Schumann, G. G., 8 Jan 2016, In : Nature Communications. 7, p. 10286

    Research output: Contribution to journalArticle

  18. Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility

    Wissing, S., Muñoz-Lopez, M., Macia, A., Yang, Z., Montano, M., Collins, W., Garcia-Perez, J. L., Moran, J. V. & Greene, W. C., 1 Jan 2012, In : Human Molecular Genetics. 21, 1, p. 208-18 11 p.

    Research output: Contribution to journalArticle

  19. RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition

    Benitez-Guijarro, M., Lopez-Ruiz, C., Tamauskaite, Z., Murina, O., Mohammad, M. M., Williams, T. C., Fluteau, A., Sanchez, L., Vilar-Astasio, R., Garcia-Cañadas, M., Cano, D., Kempen, M-J., Sanchez-Pozo, A., Heras, S. R., Jackson, A. P., Reijns, M. A. M. & Garcia-Perez, J. L., 29 Jun 2018, In : EMBO Journal.

    Research output: Contribution to journalArticle

  20. Molecular characterization of KMP11 from Trypanosoma cruzi: a cytoskeleton-associated protein regulated at the translational level

    Thomas, M. C., García-Pérez, J. L., Alonso, C. & López, M. C., Jan 2000, In : DNA and cell biology. 19, 1, p. 47-57 11 p.

    Research output: Contribution to journalArticle

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