Edinburgh Research Explorer

Prof Karen Horsburgh

Personal Chair of Neuroscience

  1. 2019
  2. Small Vessel Disease Pathological Changes in Neurodegenerative and Vascular Dementias concomitant with Autonomic Dysfunction

    Hase, Y., Polvikoski, T., Firbank, M., Craggs, L., Hawthorne, E., Platten, C., Stevenson, W., Deramecourt, V., Ballard, C., Kenny, R., Perry, R., Ince, P., Carare, R., Allan, L., Horsburgh, K. & Kalaria, R., 29 Jul 2019, In : Brain Pathology.

    Research output: Contribution to journalArticle

  3. Carotid Artery Disease in Post-Stroke Survivors and Effects of Enriched Environment on Stroke Pathology in a Mouse Model of Carotid Artery Stenosis

    Hase, Y., Polvikoski, T. M., Ihara, M., Hase, M., Zafar, R., Stevenson, W., Allan, L. M., Ennaceur, A., Horsburgh, K., Gallart-Palau, X., Kwan Sze, S. & Kalaria, R. N., 4 Apr 2019, In : Neuropathology and Applied Neurobiology.

    Research output: Contribution to journalArticle

  4. 2018
  5. 4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease

    Jones, F. E., Murray, L. S., McNeilly, S., Dean, A., Aman, A., Lu, Y., Nikolova, N., Malomgré, R., Horsburgh, K., Holmes, W. M., Kadler, K. E. & Van Agtmael, T., 22 Oct 2018, In : Human Molecular Genetics.

    Research output: Contribution to journalArticle

  6. Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

    Sigfridsson, E., Marangoni, M., Johnson, J. A., Hardingham, G. E., Fowler, J. H. & Horsburgh, K., 22 Aug 2018, In : Scientific Reports. 8, 1

    Research output: Contribution to journalArticle

  7. 'Small vessels, dementia and chronic diseases -molecular mechanisms and pathophysiology' Workshop proceedings

    Horsburgh, K., Wardlaw, J., Van Agtmael, T., Allan, S., Ashford, M., Bath, P. M., Brown, R., Berwick, J., Cader, M. Z., Carare, R. O., Davies, J. B., Duncombe, J., Farr, T. D., Fowler, J., Goense, J., Granata, A., Hall, C., Hainsworth, A., Harvey, A., Hawkes, C. & 26 others, Joutel, A., Kalaria, R. N., Kehoe, P. G., Lawrence, C. B., Lockhart, A., Love, S., MacLeod, M., Macrae, M., Markus, H. S., McCabe, C., McColl, B., Meakin, P. J., Miller, A. A., Nedergaard, M., O'Sullivan, M., Quinn, T., Rajani, R., Saksida, L. M., Smith, C., Smith, K. J., Touyz, R., Trueman, R., Wang, T., Williams, A., Williams, S. & Work, L. M., 30 Apr 2018, In : Clinical science. 132, 8, p. 851-868

    Research output: Contribution to journalReview article

  8. Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease

    Manso Sanz, Y., Holland, P., Kitamura, A., Szymkowiak, S., Duncombe, J., Hennessy, E., Searcy, J., Marangoni, M., Randall, A. D., Brown, J., McColl, B. & Horsburgh, K., Jan 2018, In : Glia. 66, 1, p. 34-46

    Research output: Contribution to journalArticle

  9. The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion

    Hase, Y., Craggs, L., Hase, M., Stevenson, W., Slade, J., Chen, A., Liang, D., Ennaceur, A., Oakley, A., Ihara, M., Horsburgh, K. & Kalaria, R. N., Jan 2018, In : Journal of Cerebral Blood Flow and Metabolism. 38, 1, p. 271678X17694904

    Research output: Contribution to journalArticle

  10. 2017
  11. White Matter Degeneration in Vascular and Other Ageing-Related Dementias

    Hase, Y., Horsburgh, K., Ihara, M. & Kalaria, R. N., 6 Dec 2017, In : Journal of Neurochemistry.

    Research output: Contribution to journalReview article

  12. Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis

    Duncombe, J., Lennen, R. J., Jansen, M. A., Marshall, I., Wardlaw, J. M. & Horsburgh, K., Oct 2017, In : Neuropathology and Applied Neurobiology. 43, 6

    Research output: Contribution to journalArticle

  13. Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia

    Duncombe, J., Kitamura, A., Hase, Y., Ihara, M., Kalaria, R. N. & Horsburgh, K., 28 Sep 2017, In : Clinical science. 131, 19, p. 2451-2468 18 p.

    Research output: Contribution to journalArticle

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