Edinburgh Research Explorer

Laura Lettice

Senior Scientist

  1. 2019
  2. Developmentally regulated Shh expression is robust to TAD perturbations

    Williamson, I., Kane, L., Devenney, P. S., Flyamer, I. M., Anderson, E., Kilanowski, F., Hill, R. E., Bickmore, W. A. & Lettice, L., 30 Sep 2019, In : Development.

    Research output: Contribution to journalArticle

  3. 2017
  4. The conserved sonic hedgehog limb enhancer consists of discrete functional elements that regulate precise spatial expression

    Lettice, L. A., Devenney, P. S., De Angelis, C. & Hill, R. E., 8 Aug 2017, In : Cell Reports. 20, 6, p. 1396-1408 13 p.

    Research output: Contribution to journalArticle

  5. 2016
  6. SBE6, a novel long-range enhancer involved in driving Sonic Hedgehog expression in neural progenitor cells

    Benabdallah, N. S., Gautier, P., Hekimoglu-Balkan, B., Lettice, L., Bhatia, S. & Bickmore, W. A., 16 Nov 2016, In : Open Biology.

    Research output: Contribution to journalArticle

  7. Shh and ZRS enhancer colocalisation is specific to the zone of polarizing activity

    Williamson, I., Lettice, L. A., Hill, R. E. & Bickmore, W. A., 15 Aug 2016, In : Development. 143, 16, p. 2994-3001 8 p.

    Research output: Contribution to journalArticle

  8. Use of a conditional Ubr5 mutant allele to investigate the role an N-end rule ubiquitin-protein ligase in Hedgehog signalling and embryonic limb development

    Kinsella, E., Dora, N., Mellis, D., Lettice, L., Deveney, P., Hill, R. & Ditzel, M., 14 Jun 2016, In : PLoS ONE.

    Research output: Contribution to journalArticle

  9. Ribonuclease H2 mutations induce a cGASSTING-dependent innate immune response

    Mackenzie, K. J., Carroll, P., Lettice, L., Tarnauskaite, Z., Reddy, K., Dix, F., Revuelta, A., Abbondati, E., Rigby, R. E., Rabe, B., Kilanowski, F., Grimes, G. R., Fluteau, A., Devenney, P. S., Hill, R. E., Reijns, M. A. M. & Jackson, A. P., 15 Apr 2016, In : EMBO Journal.

    Research output: Contribution to journalArticle

  10. Comparison of conventional & cloning free methods of generating CRISPR/Cas mutant mice

    Devenney, P. S., Ozdemir, D. D., Lettice, L. A., Hastie, N. D. & Hohenstein, P., 2016, In : Transgenic Research. 25, 2, p. 229 1 p.

    Research output: Contribution to journalMeeting abstract

  11. 2015
  12. Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid

    Semple, F., MacPherson, H., Webb, S., Kilanowski, F., Lettice, L., McGlasson, S. L., Wheeler, A. P., Chen, V., Millhauser, G. L., Melrose, L., Davidson, D. J. & Dorin, J. R., 8 Dec 2015, In : PLoS Genetics. 11, 12, p. e1005673

    Research output: Contribution to journalArticle

  13. 2014
  14. Mapping the Shh long-range regulatory domain

    Anderson, E., Devenney, P. S., Hill, R. E. & Lettice, L. A., 7 Oct 2014, In : Development. 141, 20, p. 3934-3943 10 p.

    Research output: Contribution to journalArticle

  15. Wt1 regulates the expression of inhibitory chemokines during heart development

    Velecela, V., Lettice, L. A., Chau, Y. Y., Gunst, Q. D., Van den Hoff, M., Reina, M., Martinez, F. O., Hastie, N. D. & Martinez-Estrada, O. M., 15 Jul 2014, In : Cardiovascular Research. 103, p. S57–S94 1 p.

    Research output: Contribution to journalMeeting abstract

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