Edinburgh Research Explorer

Dr Lenny Nelson

Senior Research Associate

  1. 2020
  2. TECHNOLOGIES FOR MAMMALIAN SYNTHETIC BIOLOGY

    Nelson, L. & Elfick, A., 2020, MAMMALIAN SYNTHETIC BIOLOGY: Published in partnership with the Royal Society of Biology. Davies, J. A. & Freemont, P. (eds.). Oxford University Press, (Oxford Biology Primers).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  3. 2019
  4. A sublethal dose of acetaminophen suffices to induce the unfolded protein response in hepatocytes through an IRE1alpha-JNK1-XBP1s-dependent mechanism

    Ye, H., Zheng, K., Nevzorova, Y., Martin, B., Nelson, L. J., Gomez del Moral, M., Asensio, I., Vaquero, J., Banares, R., Martinez-Naves, E. & Javier Cubero, F., Apr 2019, In : Journal of Hepatology. 70, p. E432-E433 2 p.

    Research output: Contribution to journalMeeting abstract

  5. Chlorpromazine toxicity is associated with disruption of cell membrane integrity and initiation of a pro-inflammatory response in the HepaRG hepatic cell line

    Morgan, F., Martucci, N., Kozlowska, A., Gamal, W., Brzeszczynki, F., Treskes, P., Samuel, K., Hayes, P., Nelson, L., Bagnaninchi, P., Brzeszczynska, J. & Plevris, J., Mar 2019, In : Biomedicine and Pharmacotherapy. 111, p. 1408-1416 9 p.

    Research output: Contribution to journalArticle

  6. Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury

    Zoubek, M. E., Woitok, M. M., Sydor, S., Nelson, L. J., Bechmann, L. P., Lucena, M. I., Andrade, R. J., Bast, A., Koek, G. H., Trautwein, C. & Cubero, F. J., Jan 2019, In : The Journal of Pathology. 247, 1, p. 110-122 13 p.

    Research output: Contribution to journalArticle

  7. 2018
  8. Alcoholic liver disease: Utility of animal models

    Lamas-Paz, A., Hao, F., Nelson, L. J., Teresa Vazquez, M., Canals, S., Gomez del Moral, M., Martinez-Naves, E., Nevzorova, Y. A. & Javier Cubero, F., 7 Dec 2018, In : World journal of gastroenterology : WJG. 24, 45, p. 5063-5075 13 p.

    Research output: Contribution to journalReview article

  9. Dissecting the molecular pathophysiology of drug-induced liver injury

    Ye, H., Nelson, L. J., Gómez Del Moral, M., Martínez-Naves, E. & Cubero, F. J., 7 Apr 2018, In : World journal of gastroenterology : WJG. 24, 13, p. 1373-1385 13 p.

    Research output: Contribution to journalReview article

  10. Nondestructive Optical Toxicity Assays of 3D Liver Spheroids with Optical Coherence Tomography

    Martucci, N. J., Morgan, K., Anderson, G. W., Hayes, P. C., Plevris, J. N., Nelson, L. J. & Bagnaninchi, P. O., Mar 2018, In : Advanced Biosystems. 2, 3, p. 1700212

    Research output: Contribution to journalArticle

  11. 2017
  12. Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury

    Sydor, S., Manka, P., Best, J., Jafoui, S., Sowa, J-P., Zoubek, M. E., Hernandez-Gea, V., Cubero, F. J., Kälsch, J., Vetter, D., Fiel, M. I., Hoshida, Y., Bian, C. B., Nelson, L. J., Moshage, H., Faber, K. N., Paul, A., Baba, H. A., Gerken, G., Friedman, S. L. & 2 othersCanbay, A. & Bechmann, L. P., 14 Aug 2017, In : Scientific Reports. 7, 1, p. 8119

    Research output: Contribution to journalArticle

  13. Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatocytes and mouse liver

    Gamal, W., Treskes, P., Samuel, K., Sullivan, G., Siller, R., Srsen, V., Morgan, F., Bryans, A., Kozlowska, A., Koulovasilopoulos, A., Underwood, I., Smith, S., Del-Pozo, J., Moss, S., Thompson, A. I., Henderson, N., Hayes, P., Plevris, J., Bagnaninchi, P. & Nelson, L., 30 Jan 2017, In : Scientific Reports. 7, p. 37541 37541 .

    Research output: Contribution to journalArticle

  14. Development of a novel 3D organotypic human HepaRG-based non-invasive imaging platform for pre-clinical drug screening

    Martucci, N. J., Morgan, K., Anderson, G., Hayes, P. C., Plevris, J. N., Bagnaninchi, P. O. & Nelson, L., 2017, In : Journal of Hepatology. 66, 1, p. S400-S400 1 p.

    Research output: Contribution to journalMeeting abstract

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