Edinburgh Research Explorer

Dr Luke Boulter

Chancellor's Fellow

  1. TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence

    Bird, T., Müller, M., Boulter, L., Vincent, D. F., Ridgway, R. A., Lopez-Guadamillas, E., Lu, W-Y., Jamieson, T., Govaere, O., Campbell, A. D., Ferreira Gonzalez, S., Cole, A. M., Hay, T., Simpson, K. J., Clark, W., Hedley, A., Clarke, M., Gentaz, P., Nixon, C., Bryce, S. & 14 others, Kiourtis, C., Sprangers, J., Nibbs, R. J. B., van Rooijen, N., Bartholin, L., McGreal, S. R., Apte, U., Barry, S. T., Iredale, J., Clarke, A. R., Serrano, M., Roskams, T. A., Sansom, O. J. & Forbes, S., 16 Aug 2018, In : Science translational medicine.

    Research output: Contribution to journalArticle

  2. A NOVEL MODEL OF HEPATIC PROGENITOR CELL ACTIVATION USING HEPATOCYTE SPECIFIC MDM2 DELETION DEMONSTRATES COMPLETE PARENCHYMAL REGENERATION FROM PROGENITOR CELLS IN A TWEAK/FN14 DEPENDENT MANNER

    Bird, T. G., Cole, A., Hay, T., Boulter, L. G., Iredale, J. P., Clarke, A. R., Sansom, O. J. & Forbes, S. J., Oct 2010, In : Hepatology. 52, 4, p. 970A-970A 1 p.

    Research output: Contribution to journalMeeting abstract

  3. Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling

    Bird, T. G., Lu, W-Y., Boulter, L., Gordon-Keylock, S., Ridgway, R. A., Williams, M. J., Taube, J., Thomas, J. A., Wojtacha, D., Gambardella, A., Sansom, O. J., Iredale, J. P. & Forbes, S. J., 16 Apr 2013, In : Proceedings of the National Academy of Sciences. 110, 16, p. 6542-6547 6 p.

    Research output: Contribution to journalArticle

  4. Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

    Boulter, L., Govaere, O., Bird, T. G., Radulescu, S., Ramachandran, P., Pellicoro, A., Ridgway, R. A., Seo, S. S., Spee, B., Van Rooijen, N., Sansom, O. J., Iredale, J. P., Lowell, S., Roskams, T. & Forbes, S. J., Apr 2012, In : Nature Medicine. 18, 4, p. 572-579 8 p.

    Research output: Contribution to journalArticle

  5. Differentiation of progenitors in the liver: a matter of local choice

    Boulter, L., Lu, W-Y. & Forbes, S. J., 1 May 2013, In : Journal of Clinical Investigation. 123, 5, p. 1867-1873 7 p.

    Research output: Contribution to journalArticle

  6. NOTCH SIGNALLING IS AN IMPORTANT MEDIATOR OF CELL FATE SPECIFICATION DURING HEPATIC PROGENITOR CELL MEDIATED REGENERATION

    Boulter, L. G., Lowell, S. & Forbes, S. J., Apr 2009, In : Journal of Hepatology. 50, Supplement 1, p. S305-S305 1 p.

    Research output: Contribution to journalMeeting abstract

  7. WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited.

    Boulter, L., Guest, R. V., Kendall, T. J., Wilson, D. H., Wojtacha, D., Robson, A. J., Ridgway, R. A., Samuel, K., Van Rooijen, N., Barry, S. T., Wigmore, S. J., Sansom, O. J. & Forbes, S. J., 3 Mar 2015, In : Journal of Clinical Investigation. 125, 3, p. 1269–1285

    Research output: Contribution to journalArticle

  8. Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers

    Carotenuto, P., Fassan, M., Pandolfo, R., Lampis, A., Vicentini, C., Cascione, L., Paulus-Hock, V., Boulter, L., Guest, R., Quagliata, L., Hahne, J. C., Ridgway, R., Jamieson, T., Athineos, D., Veronese, A., Visone, R., Murgia, C., Ferrari, G., Guzzardo, V., Evans, T. R. J. & 12 others, MacLeod, M., Feng, G. J., Dale, T., Negrini, M., Forbes, S. J., Terracciano, L., Scarpa, A., Patel, T., Valeri, N., Workman, P., Sansom, O. & Braconi, C., Jul 2017, In : Gut.

    Research output: Contribution to journalArticle

  9. Next generation of ALDH substrates and their potential to study maturational lineage biology in stem and progenitor cells

    Dollé, L., Boulter, L., Leclercq, I. A. & van Grunsven, L. A., 1 Apr 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 308, 7, p. G573-8

    Research output: Contribution to journalArticle

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