Edinburgh Research Explorer

Prof Malcolm Walkinshaw

Chair of Structural Biochemistry

  1. 2020
  2. Structural and kinetic characterisation of Trypanosoma congolense pyruvate kinase

    Pinto Torres, J. E., Yuan, M., Goossens, J., Versées, W., Caljon, G., Michels, P. A., Walkinshaw, M. D., Magez, S. & Sterckx, Y. G., 19 Feb 2020, In : Molecular and Biochemical Parasitology. 236, 111263.

    Research output: Contribution to journalArticle

  3. Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A

    Juárez-jiménez, J., Gupta, A. A., Karunanithy, G., Mey, A. S. J. S., Georgiou, C., Ioannidis, H., De Simone, A., Barlow, P. N., Hulme, A. N., Walkinshaw, M. D., Baldwin, A. J. & Michel, J., 15 Jan 2020, In : Chemical Science.

    Research output: Contribution to journalArticle

  4. 2019
  5. Pyruvate Kinase regulates the Pentose-Phosphate pathway in Response to Hypoxia in Mycobacterium tuberculosis

    Zhong, W., Guo, J., Cui, L., Chionh, Y. H., Li, K., El Sahili, A., Cai, Q., Yuan, M., Michels, P. A. M., Fothergill-Gilmore, L. A., Walkinshaw, M. D., Mu, Y., Lescar, J. & Dedon, P. C., 2 Aug 2019, In : Journal of Molecular Biology.

    Research output: Contribution to journalArticle

  6. Allosteric effects in cyclophilin mutants may be explained by changes in nano-microsecond time scale motions

    Wapeesittipan, P., Mey, A. S. J. S., Walkinshaw, M. D. & Michel, J., 29 Mar 2019, In : Communications Chemistry. 2, 1, 41.

    Research output: Contribution to journalArticle

  7. The kinetic characteristics of human and trypanosomatid phosphofructokinases for the reverse reaction

    Fernandes, P. M., Kinkead, J. R., McNae, I. W., Michels, P. A. & Walkinshaw, M. D., 18 Jan 2019, In : Biochemical Journal. 476, 2, p. 179-191 13 p.

    Research output: Contribution to journalArticle

  8. Oligopeptide Signaling through TbGPR89 Drives Trypanosome Quorum Sensing

    Rojas, F., Silvester, E., Young, J., Milne, R., Tettey, M., Houston, D. R., Walkinshaw, M. D., Pérez-Pi, I., Auer, M., Denton, H., Smith, T. K., Thompson, J. & Matthews, K. R., 10 Jan 2019, In : Cell. 176, 1-2, p. 306-317.e16 28 p.

    Research output: Contribution to journalArticle

  9. 2018
  10. Demonstration of the Anthelmintic Potency of Marimastat in the Heligmosomoides Polygyrus Rodent Model

    Robertson, E., Harcus, Y., Johnston, C. J. C., Page, A. P., Walkinshaw, M. D., Maizels, R. M. & Houston, D., 1 Dec 2018, In : Journal of parasitology. 104, 6, p. 705-709 5 p.

    Research output: Contribution to journalArticle

  11. Redox regulation of pyruvate kinase M2 by cysteine oxidation and S-nitrosation

    Mitchell, A. R., Yuan, M., Morgan, H. P., McNae, I. W., Blackburn, E. A., LeBihan, T., Homem, R. A., Yu, M., Loake, G. J., Michels, P. A., Wear, M. A. & Walkinshaw, M. D., 31 Oct 2018, In : Biochemical Journal. 475, 20, p. 3275-3291 17 p.

    Research output: Contribution to journalArticle

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