Edinburgh Research Explorer

Prof Margaret Frame

Chair of Cancer Biology

  1. 2019
  2. A Synergistic Anti-Cancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical-Genetic High-Content Phenotypic Screen

    Dawson, J., Serrels, B., Byron, A., Muir, M., Makda, A., Garcia-Munoz, A., Von Kriegsheim, A., Lietha, D., Carragher, N. & Frame, M., 29 Nov 2019, In : Molecular Cancer Therapeutics.

    Research output: Contribution to journalArticle

  3. 2018
  4. Funding mechanisms risk promoting conscious bias

    Bickmore, W., Cunningham-burley, S. & Frame, M., 10 Oct 2018, In : Nature. 562, 7726, p. 192-192

    Research output: Contribution to journalLetter

  5. Trafficking of Adhesion and Growth Factor Receptors and their Effector Kinases

    Schoenherr, C., Frame, M. & Byron, A., 15 Aug 2018, In : Annual Review of Cell and Developmental Biology.

    Research output: Contribution to journalReview article

  6. Structure-based design, synthesis and characterization of the first irreversible inhibitor of Focal Adhesion Kinase

    Yen-Pon, E., Li, B., Acebron-Garcia de Eulate, M., Tomkieqicz-Raulet, C., Dawson, J., Lietha, D., Frame, M., Coumoul, X., Garbay, C., Etheve-Quelquejeu, M. & Chen, H., 13 Jun 2018, In : Acs chemical biology.

    Research output: Contribution to journalArticle

  7. Rapid Polymer Conjugation Strategies for the Generation of pH-Responsive, Cancer Targeting, Polymeric Nanoparticles

    Li, W., Geng, J., Titmarsh, H., Megia-fernandez, A., Dhaliwal, K., Frame, M. & Bradley, M., 24 Apr 2018, In : Biomacromolecules.

    Research output: Contribution to journalArticle

  8. 2017
  9. Ambra1 spatially regulates Src activity 1 and Src/FAK-mediated cancer cell invasion via trafficking networks

    Schoenherr, C., Byron, A., Sandilands, E., Paliashvili, K., Baillie, G. S., Valacca, C., Cecconi, F., Serrels, B. & Frame, M., 31 Mar 2017, In : eLIFE.

    Research output: Contribution to journalArticle

  10. 2016
  11. Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells

    Spender, L. C., Ferguson, G. J., Liu, S., Cui, C., Romina Girotti, M., Sibbet, G., Higgs, E. B., K. Shuttleworth, M., Hamilton, T., Lorigan, P., Weller, M., Vincent, D. F., Sansom, O. J., Frame, M., ten Dijke, P., Marais, R. & J. Inman, G., 9 Nov 2016, In : Oncotarget.

    Research output: Contribution to journalArticle

  12. Cellular functions of the ADF/cofilin family at a glance

    Kanellos, G. & Frame, M. C., 9 Aug 2016, In : Journal of Cell Science.

    Research output: Contribution to journalLiterature review

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