Edinburgh Research Explorer
  1. 2016
  2. A brain imaging repository of normal structural MRI across the life course: Brain Images of Normal Subjects (BRAINS)

    Job, D., Dickie, D. A., Rodriguez Gonzalez, D., Robson, A., Danso, S., Pernet, C., Bastin, M., Boardman, J. P., Murray, A. D., Ahearn, T. S., Waiter, G. D., Staff, R. T., Deary, I., Shenkin, S. D. & Wardlaw, J., 18 Jan 2016, In : NeuroImage.

    Research output: Contribution to journalArticle

  3. Epigenomic profiling of preterm infants reveals DNA methylation differences at sites associated with neural function

    Sparrow, S., Manning, J., Cartier, J., Anblagan, D., Bastin, M., Piyasena, C., Pataky, R., Moore, E. J., Semple, S. I., Wilkinson, A., Evans, M., Drake, A. J. & Boardman, J. P., 16 Jan 2016, In : Translational Psychiatry.

    Research output: Contribution to journalArticle

  4. 2015
  5. Progression of white matter disease and cortical thinning are not related in older community-dwelling subjects

    Dickie, D. A., Karama, S., Ritchie, S. J., Cox, S. R., Sakka, E., Royle, N. A., Aribisala, B. S., Hernández, M. V., Maniega, S. M., Pattie, A., Corley, J., Starr, J. M., Bastin, M. E., Evans, A. C., Deary, I. J. & Wardlaw, J. M., 22 Dec 2015, In : Stroke. 47, 2, p. 410-6 7 p.

    Research output: Contribution to journalArticle

  6. APOE/TOMM40 genetic loci, white matter hyperintensities and cerebral microbleeds

    Lyall, D. M., Munoz-Maniega, S., Harris, S., Bastin, M., Murray, C., Lutz, M. W., Saunders, A. M., Roses, A. D., Valdes Hernandez, M., Royle, N., Starr, J., Porteous, D., Deary, I. & Wardlaw, J., Dec 2015, In : International Journal of Stroke. 10, 8, p. 1297-1300

    Research output: Contribution to journalArticle

  7. Brain volumetric changes and cognitive ageing during the eighth decade of life

    Ritchie, S. J., Dickie, D., Cox, S., Valdes Hernandez, M., Corley, J., Royle, N., Pattie, A., Aribisala, B., Redmond, P., Munoz-Maniega, S., Taylor, A., Sibbett, R., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Dec 2015, In : Human Brain Mapping. 36, p. 4910–4925

    Research output: Contribution to journalArticle

  8. Permutation and parametric tests for effect sizes in voxel-based morphometry of grey matter volume in brain structural MRI

    Dickie, D. A., Mikhael, S., Job, D. E., Wardlaw, J. M., Laidlaw, D. H. & Bastin, M. E., Dec 2015, In : Magnetic Resonance Imaging. 33, p. 1299-1305

    Research output: Contribution to journalArticle

  9. Brain iron deposits and lifespan cognitive ability

    Valdes Hernandez, M., Ritchie, S. J., Glatz, A., Allerhand, M., Munoz-Maniega, S., Gow, A., Royle, N., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., Oct 2015, In : AGE. 37, p. 100

    Research output: Contribution to journalArticle

  10. Post-mortem brain analyses of the Lothian Birth Cohort 1936: Extending lifetime cognitive and brain phenotyping to the level of the synapse

    Henstridge, C., JAckson, R., Kim, J., Herrmann, A., Wright, A. K., Harris, S., Bastin, M., Starr, J., Wardlaw, J., Gillingwater, T., Smith, C., McKenzie, C-A., Cox, S., Deary, I. & Spires-Jones, T., 4 Sep 2015, In : Acta neuropathologica communications. 3, 53

    Research output: Contribution to journalArticle

  11. Tract shape modeling detects changes associated with preterm birth and neuroprotective treatment effects

    Anblagan, D., Bastin, M., Sparrow, S., Piyasena, C., Pataky, R., Moore, E., Serag, A., Wilkinson, AG., Clayden, JD., Semple, S. & Boardman, J., Aug 2015, In : NeuroImage: Clinical. 8, p. 51-58

    Research output: Contribution to journalArticle

  12. Beyond a bigger brain: Multivariable structural brain imaging and intelligence

    Ritchie, S., Booth, T., Valdes Hernandez, M., Corley, J., Munoz-Maniega, S., Gow, A., Royle, N., Pattie, A., Karama, S., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Jul 2015, In : Intelligence. 51, p. 47–56 10 p.

    Research output: Contribution to journalArticle

  13. White matter integrity and its association with affective and interpersonal symptoms in borderline personality disorder

    Whalley, H. C., Nickson, T., Pope, M., Nicol, K., Romaniuk, L., Bastin, M. E., Semple, S. I., McIntosh, A. M. & Hall, J., Jul 2015, In : NeuroImage: Clinical. 7, p. 476-81 6 p.

    Research output: Contribution to journalArticle

  14. Effects of a balanced translocation between chromosomes 1 and 11 disrupting the DISC1 locus on white matter integrity

    Whalley, H., Dimitrova, R., Sprooten, E., Dauvermann, M. R., Romaniuk, L., Duff, B., Watson, A., Moorhead, B., Bastin, M., Semple, S. I., Giles, S., Hall, J., Thomson, P., Roberts, N., Hughes, Z., J Brandon, N., Dunlop, J., Whitcher, B., Blackwood, D., McIntosh, A. & 1 others, Lawrie, S., 23 Jun 2015, In : PLoS ONE.

    Research output: Contribution to journalArticle

  15. Coupled changes in brain white matter microstructure and fluid intelligence in later life

    Ritchie, S., Bastin, M., Tucker-Drob, E. M., Munoz-Maniega, S., Engelhardt, L., Cox, S. R., Royle, N., Gow, A., Corley, J., Pattie, A., Taylor, A., Valdes Hernandez, M., Starr, J., Wardlaw, J. & Deary, I., 3 Jun 2015, In : The Journal of Neuroscience. 35, 22, p. 8672-8682 11 p.

    Research output: Contribution to journalArticle

  16. Memory binding and white matter integrity in familial Alzheimer's disease

    Parra, M. A., Saarimäki, H., Bastin, M. E., Londoño, A. C., Pettit, L., Lopera, F., Della Sala, S. & Abrahams, S., 1 May 2015, In : Brain. 138, p. 1355-1369 15 p.

    Research output: Contribution to journalArticle

  17. Reduced structural connectivity within a prefrontal-motor-subcortical network in amyotrophic lateral sclerosis

    Buchanan, C. R., Pettit, L. D., Storkey, A. J., Abrahams, S. & Bastin, M. E., May 2015, In : Journal of Magnetic Resonance Imaging. 41, 5, p. 1342-1352 11 p.

    Research output: Contribution to journalArticle

  18. Intelligence in childhood and atherosclerosis of the carotid and peripheral arteries in later life: The Lothian Birth Cohort 1936

    Gale, C., Eadie, E., Thomas, A., Bastin, M., Starr, J., Wardlaw, J. & Deary, I., 27 Apr 2015, In : PLoS ONE. 10, 4, 7 p., e0125280.

    Research output: Contribution to journalArticle

  19. Common genetic variants influence human subcortical brain structures

    Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 31 others, Cuellar-Partida, G., den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., Macare, C., Liewald, D. C. M., Lopez, L. M., Royle, N. A., Bastin, M. E., Lawrie, S. M., Smith, C., Sussmann, J. E., Valdés Hernández, M. C., Deary, I. J., McIntosh, A. M., Wardlaw, J. M. & The Alzheimer’s Disease Neuroimaging Initiative, 9 Apr 2015, In : Nature. 520, 7546, p. 224-U216 21 p.

    Research output: Contribution to journalLetter

  20. Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data

    Kochunov, P., Jahanshad, N., Marcus, D., Winkler, A., Sprooten, E., Nichols, T. E., Wright, S. N., Hong, L. E., Patel, B., Behrens, T., Jbabdi, S., Andersson, J., Lenglet, C., Yacoub, E., Moeller, S., Auerbach, E., Ugurbil, K., Sotiropoulos, S. N., Brouwer, R. M., Landman, B. & 33 others, Lemaitre, H., den Braber, A., Zwiers, M. P., Ritchie, S., van Hulzen, K., Almasy, L., Curran, J., deZubicaray, G. I., Duggirala, R., Fox, P., Martin, N. G., McMahon, K. L., Mitchell, B., Olvera, R. L., Peterson, C., Starr, J., Sussmann, J., Wardlaw, J., Wright, M., Boomsma, D. I., Kahn, R., de Geus, E. J. C., Williamson, D. E., Hariri, A., van 't Ent, D., Bastin, M. E., McIntosh, A., Deary, I. J., Hulshoff Pol, H. E., Blangero, J., Thompson, P. M., Glahn, D. C. & Van Essen, D. C., 4 Mar 2015, In : NeuroImage. 111, p. 300-311 12 p.

    Research output: Contribution to journalArticle

  21. Association of allostatic load with brain structure and cognitive ability in later life

    Booth, T., Royle, N. A., Corley, J., Gow, A. J., Valdés Hernández, M. D. C., Munoz-Maniega, S., Ritchie, S. J., Bastin, M. E., Starr, J. M., Wardlaw, J. M. & Deary, I. J., Mar 2015, In : Neurobiology of Aging. 36, 3, p. 1390-1399 10 p.

    Research output: Contribution to journalArticle

  22. Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease

    Holland, P., Searcy, L., Salvadores, N., Scullion, G., Chen, G., Lawson, G., Scott, F., Bastin, M., Ihara, M., Kalaria, R. N., Wood, E., Smith, C., Wardlaw, J. & Horsburgh, K., 21 Feb 2015, In : Journal of Cerebral Blood Flow and Metabolism. 35, 6, p. 1005-1014

    Research output: Contribution to journalArticle

  23. Cigarette smoking and thinning of the brain's cortex

    Karama, S., Ducharme, S., Corley, J., Chouinard-Decorte, F., Starr, J., Wardlaw, J., Bastin, M. & Deary, I., 10 Feb 2015, In : Molecular Psychiatry. 20, p. 778–785

    Research output: Contribution to journalArticle

  24. Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats

    Holland, P. R., Pannozzo, M. A., Bastin, M. E., McNeilly, A. D., Ferguson, K. J., Caughey, S., Jansen, M. A., Merrifield, G. D., Marshall, I., Mullins, J. J., Wardlaw, J. M., Sutherland, C. & Horsburgh, K., Feb 2015, In : Journal of Cerebral Blood Flow and Metabolism. 35, p. 188-192

    Research output: Contribution to journalArticle

  25. White matter hyperintensities and normal-appearing white matter integrity in the ageing brain

    Munoz-Maniega, S., Valdes Hernandez, M., Clayden, J. D., Royle, N., Murray, C., Morris, Z., Aribisala, B., Gow, A., Starr, J., Bastin, M., Deary, I. & Wardlaw, J., Feb 2015, In : Neurobiology of Aging. 36, 2, p. 909-918

    Research output: Contribution to journalArticle

  26. Automated segmentation of multifocal basal ganglia T2*-weighted MRI hypointensities

    Glatz, A., Bastin, M., Kiker, AJ., Deary, I., Wardlaw, J. & Hernandez, M. D. C. V., 15 Jan 2015, In : NeuroImage. 105, p. 332-346 15 p.

    Research output: Contribution to journalArticle

  27. Exploratory analysis of dietary intake and brain iron accumulation detected using magnetic resonance imaging in older individuals: the Lothian Birth Cohort 1936

    Valdes Hernandez, M., Allan, J., Glatz, A., Kyle, J., Corley, J., Brett, C., Munoz-Maniega, S., Royle, N., Bastin, M., Starr, J., Deary, I. & Wardlaw, J., Jan 2015, In : The Journal of Nutrition, Health & Aging. 19, 1, p. 64-69

    Research output: Contribution to journalArticle

  28. A comparison of location of acute symptomatic versus 'silent' small vessel lesions

    Valdes Hernandez, M., Maconick, L. C., Munoz-Maniega, S., Wang, X., Wiseman, S., Armitage, P., Doubal, F., Makin, S., Sudlow, C., Dennis, M., Deary, I., Bastin, M. & Wardlaw, J., 2015, In : International Journal of Stroke. 10, p. 1044–1050

    Research output: Contribution to journalArticle

  29. Brain white matter structure and information processing speed in healthy older age

    Kuznetsova, K., Munoz-Maniega, S., Ritchie, S., Cox, S., Storkey, A., Starr, J., Wardlaw, J., Deary, I. & Bastin, M., 2015, In : Brain Structure and Function. 21, 6, p. 3323-3235

    Research output: Contribution to journalArticle

  30. Genes from a translational analysis support a multifactorial nature of white matter hyperintensities

    Lopez, L., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz-Maniega, S., Bastin, M., Bailey, E. L., Smith, C., McBride, M. W., Mcclure, J. D., Graham, D., Dominiczak, A. F., Yang, Q., Fornage, M., Ikfram, MA., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S. & 4 others, Porteous, D., Starr, J., Deary, I. & Wardlaw, J., 2015, In : Stroke. 46, 2, p. 341-347 7 p.

    Research output: Contribution to journalArticle

  31. Neural mechanisms of Trail Making Test performance

    MacPherson, S. E., Cox, S., Aribisala, B., Bastin, M., Wardlaw, J. & Deary, I., 2015, (Unpublished).

    Research output: Contribution to conferencePaper

  32. Structural brain MRI trait polygenic score prediction of cognitive abilities

    Generation Scotland & SINAPSE Collaborative Grp, 2015, In : Twin Research and Human Genetics. 18, p. 738-745 8 p.

    Research output: Contribution to journalArticle

  33. Total MRI load of cerebral small vessel disease and cognitive ability in older people

    Staals, J., Booth, T., Morris, Z., Bastin, M., Gow, A., Corley, J., Redmond, P., Starr, J., Deary, I. & Wardlaw, J., 2015, In : Neurobiology of Aging. 36, p. 2806-2811

    Research output: Contribution to journalArticle

  34. 2014
  35. Personality, Health, and Brain Integrity: The Lothian Birth Cohort Study 1936

    Booth, T., Mõttus, R., Corley, J., Gow, A. J., Henderson, R. D., Munoz-Maniega, S., Murray, C., Royle, N. A., Sprooten, E., Hernández, M. C. V., Bastin, M. E., Penke, L., Starr, J. M., Wardlaw, J. M. & Deary, I. J., Dec 2014, In : Health Psychology. 33, 12, p. 1477-1486 10 p.

    Research output: Contribution to journalArticle

  36. Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with type 2 diabetes with and without fatty liver

    Macfarlane, D. P., Raubenheimer, P. J., Preston, T., Gray, C. D., Bastin, M. E., Marshall, I., Iredale, J. P., Andrew, R. & Walker, B. R., 1 Oct 2014, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 307, 7, p. G760-768 9 p.

    Research output: Contribution to journalArticle

  37. Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity?

    Lyall, D. M., Harris, S. E., Bastin, M. E., Munoz-Maniega, S., Murray, C., Lutz, M. W., Saunders, A. M., Roses, A. D., Valdés Hernández, M., Royle, N. A., Starr, J. M., Porteous, D. J., Wardlaw, J. M. & Deary, I. J., 23 Sep 2014, In : Translational Psychiatry. 4, 9, 7 p., e449.

    Research output: Contribution to journalArticle

  38. Potential effect of skull thickening on the associations between cognition and brain atrophy in ageing

    Aribisala, B. S., Royle, N. A., Valdés Hernández, M. C., Murray, C., Penke, L., Gow, A., Munoz-Maniega, S., Starr, J. M., Bastin, M., Deary, I. & Wardlaw, J., Sep 2014, In : Age and Ageing. 43, 5, p. 712-716 5 p.

    Research output: Contribution to journalArticle

  39. Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling

    Kochunov, P., Jahanshad, N., Sprooten, E., Nichols, T. E., Mandl, R. C., Almasy, L., Booth, T., Brouwer, R. M., Curran, J. E., de Zubicaray, G. I., Dimitrova, R., Duggirala, R., Fox, P. T., Elliot Hong, L., Landman, B. A., Lemaitre, H., Lopez, L., Martin, N. G., McMahon, K. L., Mitchell, B. D. & 21 others, Olvera, R. L., Peterson, C. P., Starr, J. M., Sussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Wright, S. N., Bastin, M. E., McIntosh, A. M., Boomsma, D. I., Kahn, R. S., den Braber, A., de Geus, E. J. C., Deary, I. J., Hulshoff Pol, H. E., Williamson, D. E., Blangero, J., van 't Ent, D., Thompson, P. M. & Glahn, D. C., 15 Jul 2014, In : NeuroImage. 95, p. 136-150 15 p.

    Research output: Contribution to journalArticle

  40. Can musical training influence brain connectivity? Evidence from diffusion tensor MRI

    Moore, E., Schaefer, R., Bastin, M., Roberts, N. & Overy, K., 10 Jun 2014, In : Brain Sciences. 4, 2, p. 405-427 22 p.

    Research output: Contribution to journalArticle

  41. Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936

    Lyall, D. M., Harris, S. E., Bastin, M. E., Munoz-Maniega, S., Murray, C., Lutz, M. W., Saunders, A. M., Roses, A. D., Hernandez, M. D. C. V., Royle, N. A., Starr, J. M., Porteous, D. J., Wardlaw, J. M. & Deary, I. J., Jun 2014, In : Neurobiology of Aging. 35, 6, p. 1513.e25–1513.e33 9 p.

    Research output: Contribution to journalArticle

  42. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

    Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., Toro, R., Jahanshad, N., Schumann, G., Franke, B., Wright, M. J., Martin, N. G., Agartz, I., Alda, M., Alhusaini, S., Almasy, L., Almeida, J., Alpert, K., Andreasen, N. C., Andreassen, O. A. & 34 others, Apostolova, L. G., Appel, K., Armstrong, N. J., Aribisala, B., Bastin, M. E., Bauer, M., Bearden, C. E., Bergmann, O., Binder, E. B., Blangero, J., Bockholt, H. J., Boen, E., Bois, C., Boomsma, D. I., Booth, T., Bowman, I. J., Bralten, J., Deary, I. J., Hall, J., Lawrie, S. M., Liewald, D. C., Lopez, L. M., Luciano, M., McIntosh, A. M., Royle, N. A., Smith, C., Starr, J. M., Sussmann, J., Wardlaw, J. M., Whalley, H. C., Alzheimer's Dis Neuroimaging, EPIGEN Consortium, IMAGEN Consortium & Saguenay Youth Study SYS Grp, Jun 2014, In : Brain imaging and behavior. 8, 2, p. 153-182 30 p.

    Research output: Contribution to journalArticle

  43. Childhood cognitive ability accounts for associations between cognitive ability and brain cortical thickness in old age

    Karama, S., Bastin, M. E., Murray, C., Royle, N. A., Penke, L., Munoz-Maniega, S., Gow, A. J., Corley, J., Valdés Hernández, M., Lewis, J. D., Rousseau, M-E., Lepage, C., Fonov, V., Collins, D. L., Booth, T., Rioux, P., Sherif, T., Adalat, R., Starr, J. M., Evans, A. C. & 2 others, Wardlaw, J. M. & Deary, I. J., May 2014, In : Molecular Psychiatry. 19, 5, p. 555-559 5 p.

    Research output: Contribution to journalArticle

  44. Corrigendum to Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: A pilot project of the ENIGMA-DTI working group [NeuroImage 81 (2013) 455-469]

    Jahanshad, N., Kochunov, P. V., Sprooten, E., Mandl, R. C., Nichols, T. E., Almasy, L., Blangero, J., Brouwer, R. M., Curran, J. E., de Zubicaray, G. I., Duggirala, R., Fox, P. T., Hong, L. E., Landman, B. A., Martin, N. G., McMahon, K. L., Medland, S. E., Mitchell, B. D., Olvera, R. L., Peterson, C. P. & 11 others, Starr, J. M., Sussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Pol, H. E. H., Bastin, M. E., McIntosh, A. M., Deary, I. J., Thompson, P. M. & Glahn, D. C., 15 Apr 2014, In : NeuroImage. 90, p. 470-471 2 p.

    Research output: Contribution to journalComment/debate

  45. Quantitative multi-modal MRI of the hippocampus and cognitive ability in community-dwelling older subjects

    Aribisala, B., Royle, N., Munoz-Maniega, S., Valdes Hernandez, M., Murray, C., Penke, L., Gow, A., Starr, J., Bastin, M., Deary, I. & Wardlaw, J., Apr 2014, In : Cortex. 53C, p. 34-44 11 p.

    Research output: Contribution to journalArticle

  46. Quantitative Serial MRI of the Treated Fibroid Uterus

    Munro, K. I., Thrippleton, M., Williams, A., McKillop, G., Walker, J., Horne, A., Newby, D., Anderson, R., Semple, S., Marshall, I., Lewis, S., Millar, R., Bastin, M. & Critchley, H., 7 Mar 2014, In : PLoS ONE. 9, 3, e89809.

    Research output: Contribution to journalArticle