Edinburgh Research Explorer

Prof Mark Bradley

Chair of Chemical Biology

  1. 2019
  2. Optical Molecular Imaging of Inflammatory Cells in Interventional Medicine-An Emerging Strategy

    Birch, G. P., Campbell, T., Bradley, M. & Dhaliwal, K., 12 Sep 2019, In : Frontiers in Oncology. 9, 882.

    Research output: Contribution to journalReview article

  3. A Dual Killing Strategy - Photocatalytic Generation of Singlet Oxygen with Concomitant Pt(IV) Prodrug Activation

    Norman, D., Gambardella, A., Mount, A., Murray, A. & Bradley, M., 9 Aug 2019, In : Angewandte Chemie International Edition.

    Research output: Contribution to journalArticle

  4. Photo-Controlled One-Pot Strategy for the Synthesis of Asymmetric Three-Arm Star Polymers

    Zhang, Y., Bradley, M. & Geng, J., 25 Jul 2019, In : Polymer chemistry.

    Research output: Contribution to journalArticle

  5. High fidelity fibre-based physiological sensing deep in tissue

    Choudhary, T. R., Tanner, M. G., Megia-Fernandez, A., Harrington, K., Wood, H. A., Marshall, A., Zhu, P., Chankeshwara, S., Choudhury, D., Monro, G., Ucuncu, M., Yu, F., Duncan, R. R., Thomson, R. R., Dhaliwal, K. & Bradley, M., 22 May 2019, In : Scientific Reports.

    Research output: Contribution to journalArticle

  6. Solid-Phase Synthesis of Biocompatible N-Heterocyclic Carbene–Pd Catalysts Using a Sub-monomer Approach

    Cherukaraveedu, D., Cowling, P., Birch, G., Bradley, M. & Lilienkampf, A., 8 May 2019, In : Organic & Biomolecular chemistry.

    Research output: Contribution to journalArticle

  7. Radical polymerization inside living cells

    Geng, J., Li, W., Zhang, Y., Thottappillil, N., Clavadetscher, J., Lilienkampf, A. & Bradley, M., 15 Apr 2019, In : Nature Chemistry .

    Research output: Contribution to journalArticle

  8. Polymer Microarrays for the Discovery and Optimization of Robust Optical-Fiber-Based pH Sensors

    Gong, J., Venkateswaran, S., Tanner, M. G., Stone, J. M. & Bradley, M., 11 Apr 2019, In : ACS Combinatorial Science. 21, 5, p. 417-424

    Research output: Contribution to journalArticle

  9. Endoscopic sensing of distal lung physiology

    Choudhury, D., Tanner, M. G., McAughtrie, S., Yu, F., Mills, B., Choudhary, T. R., Seth, S., Craven, T. H., Stone, J. M., Mati, I. K., Campbell, C. J., Bradley, M., Williams, C. K. I., Dhaliwal, K., Birks, T. A. & Thomson, R. R., 18 Mar 2019, In : Journal of Physics: Conference Series. 1151, 9 p., 012009.

    Research output: Contribution to journalArticle

  10. 2018
  11. High-speed dual color fluorescence lifetime endomicroscopy for highly-multiplexed pulmonary diagnostic applications and detection of labeled bacteria

    Pedretti, E., Tanner, M. G., Choudhary, T. R., Krstajic, N., Megia-Fernandez, A., Henderson, R., Bradley, M., Thomson, R., Girkin, J. M., Dhaliwal, K. & Dalgarno, P. A., 12 Dec 2018, In : Biomedical Optics Express. 10, 1, p. 181-195 15 p.

    Research output: Contribution to journalArticle

  12. Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity

    González-Fernández, E., Staderini, M., Yussof, A., Scholefield, E., Murray, A. F., Mount, A. R. & Bradley, M., 15 Nov 2018, In : Biosensors and Bioelectronics. 119, p. 209-214 6 p.

    Research output: Contribution to journalArticle

  13. 3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo

    Rashidi, H., Luu, N-T., Alwahsh, S. M., Ginai, M., Alhaque, S., Dong, H., Tomaz, R. A., Vernay, B., Vigneswara, V., Hallett, J. M., Chandrashekran, A., Dhawan, A., Vallier, L., Bradley, M., Callanan, A., Forbes, S. J., Newsome, P. N. & Hay, D. C., 28 Aug 2018, In : Archives of toxicology.

    Research output: Contribution to journalArticle

  14. High fidelity fibre-based physiological sensing deep in tissue

    Choudhary, T. R., Tanner, M. G., Megia-Fernandez, A., Harrington, K., Wood, H. A., Marshall, A., Zhu, P., Chankeshwara, S. V., Choudhury, D., Monro, G., Ucuncu, M., Yu, F., Duncan, R. R., Thomson, R. R., Dhaliwal, K. & Bradley, M., 27 Aug 2018, (arXiv).

    Research output: Working paper

  15. Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancer

    Megia-fernandez, A., Mills, B., Michels, C., Chankeshwara, S. V., Krstajić, N., Haslett, C., Dhaliwal, K. & Bradley, M., 23 Aug 2018, In : Organic & Biomolecular chemistry.

    Research output: Contribution to journalArticle

  16. Electrodrugs: an electrochemical prodrug activation strategy

    Norman, D. J., González-Fernández, E., Clavadetscher, J., Tucker, L., Staderini, M., Mount, A. R., Murray, A. F. & Bradley, M., 24 Jul 2018, In : Chemical Communications.

    Research output: Contribution to journalArticle

  17. A tripod anchor offers improved robustness of peptide-based electrochemical biosensors

    Staderini, M., González-fernández, E., Murray, A. F., Mount, A. R. & Bradley, M., 23 Jul 2018, In : Sensors and Actuators B: Chemical.

    Research output: Contribution to journalArticle

  18. Tetrazine-mediated bioorthogonal prodrug–prodrug activation

    Neumann, K., Gambardella, A., Lilienkampf, A. & Bradley, M., 12 Jul 2018, In : Chemical Science. 9, 36, p. 7198-7203

    Research output: Contribution to journalArticle

  19. Low-cost high sensitivity pulsed endomicroscopy to visualize tricolor optical signatures

    Krstajić, N., Mills, B., Murray, I., Marshall, A., Norberg, D., Craven, T. H., Emanuel, P., Choudhary, T. R., Williams, G. O. S., Scholefield, E., Akram, A. R., Davie, A., Hirani, N., Bruce, A., Moore, A., Bradley, M. & Dhaliwal, K., 10 Jul 2018, In : Journal of Biomedical Optics. 23, 7, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  20. New substrates for stem cell control

    Schmidt, S., Lilienkampf, A. & Bradley, M., 5 Jul 2018, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 373, 1750, 8 p., 20170223.

    Research output: Contribution to journalReview article

  21. Combinatorial Delivery of Bioactive Molecules by a Nanoparticle-Decorated and Functionalized Biodegradable Scaffold

    Czekanska, E., Geng, J., Glinka, M., White, K., Kanczler, J. M., Evans, N. D., Oreffo, R. O. & Bradley, M., 14 Jun 2018, In : Journal of Materials Chemistry B.

    Research output: Contribution to journalArticle

  22. A Tetrazine-Labile Vinyl Ether Benzyloxycarbonyl Protecting Group (VeZ): An Orthogonal Tool for Solid-Phase Peptide Chemistry

    Staderini, M., Gambardella, A., Lilienkampf, A. & Bradley, M., 1 Jun 2018, In : Organic letters. 20, 11, p. 3170-3173

    Research output: Contribution to journalArticle

  23. Rapid Polymer Conjugation Strategies for the Generation of pH-Responsive, Cancer Targeting, Polymeric Nanoparticles

    Li, W., Geng, J., Titmarsh, H., Megia-fernandez, A., Dhaliwal, K., Frame, M. & Bradley, M., 24 Apr 2018, In : Biomacromolecules.

    Research output: Contribution to journalArticle

  24. 2017
  25. Acrylate-based materials for heart valve scaffold engineering

    Santoro, R., Venkateswaran, S., Amadeo, F., Zhang, R., Brioschi, M., Callanan, A., Agrifoglio, M., Banfi, C., Bradley, M. & Pesce, M., 19 Dec 2017, In : Biomaterials science. 6, 1, p. 154-167 14 p.

    Research output: Contribution to journalArticle

  26. Biodegradable pH-responsive hydrogels for controlled dual-drug release

    Xu, L., Qiu, L., Sheng, Y., Sun, Y., Deng, L., Li, X., Bradley, M. & Zhang, R., 18 Dec 2017, In : Journal of Materials Chemistry B. 6, 3, p. 510-517

    Research output: Contribution to journalArticle

  27. Peptides for optical medical imaging and steps towards therapy

    Staderini, M., Megia-fernandez, A., Dhaliwal, K. & Bradley, M., 30 Sep 2017, In : Bioorganic and Medicinal Chemistry.

    Research output: Contribution to journalArticle

  28. Effect of spacer length on the performance of peptide-based electrochemical biosensors for protease detection

    González-fernández, E., Staderini, M., Avlonitis, N., Murray, A. F., Mount, A. R. & Bradley, M., 28 Sep 2017, In : Sensors and Actuators B: Chemical.

    Research output: Contribution to journalArticle

  29. Responsive Polymeric Nanoparticles for Controlled Drug Delivery

    Neumann, K., Lilienkampf, A. & Bradley, M., 11 Sep 2017, In : Polymer International.

    Research output: Contribution to journalArticle

  30. Ballistic and snake photon imaging for locating optical endomicroscopy fibres

    Tanner, M. G., Choudhary, T. R., Craven, T. H., Mills, B., Bradley, M., Henderson, R. K., Dhaliwal, K. & Thomson, R. R., 1 Sep 2017, In : Biomedical Optics Express. 8, 9, p. 4077-4095 19 p.

    Research output: Contribution to journalArticle

  31. Controlled core-to-core photo-polymerisation – fabrication of an optical fibre-based pH sensor

    Mohamad, F., Tanner, M. G., Choudhury, D., Choudhary, T. R., Wood, H. A. C., Harrington, K. & Bradley, M., 30 Aug 2017, In : Analyst. 142, 19, p. 3569-3572

    Research output: Contribution to journalArticle

  32. Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy

    Mills, B., Akram, A-U-H., Scholefield, E., Bradley, M. & Dhaliwal, K., 13 Aug 2017, In : Journal of Visualized Experiments (JoVE).

    Research output: Contribution to journalArticle

  33. Intracellular delivery of a catalytic organometallic complex

    Indrigo, E., Clavadetscher, J., Chankeshwara, S. V., Megia-fernandez, A., Lilienkampf, A. & Bradley, M., 6 Jun 2017, In : Chemical Communications.

    Research output: Contribution to journalArticle

  34. In-Cell Dual Drug Synthesis by Cancer-Targeting Palladium Catalysts

    Clavadetscher, J., Indrigo, E., Chankeshwara, S. V., Lilienkampf, A. & Bradley, M., 9 May 2017, In : Angewandte Chemie International Edition.

    Research output: Contribution to journalArticle

  35. Time-resolved spectroscopy at 19,000 lines per second using a CMOS SPAD line array enables advanced biophotonics applications

    Kufcsak, A., Erdogan, A., Walker, R., Katjana, E., Tanner, M. G., Megia-Fernandez, A., Scholefield, E., Emanuel, P., Dhaliwal, K., Bradley, M., Henderson, R. & Krstajic, N., 4 May 2017, In : Optics Express. 25, 10, 11103-11123.

    Research output: Contribution to journalArticle

  36. Highly selective and rapidly activatable fluorogenic Thrombin sensors and application in human lung tissue

    Megia-fernandez, A., Mills, B., Michels, C., Chankeshwara, S. V., Dhaliwal, K. & Bradley, M., 28 Apr 2017, In : Organic & Biomolecular chemistry.

    Research output: Contribution to journalArticle

  37. Multiplexed fibre optic sensing in the distal lung

    Choudhary, T., Tanner, M. G., Megia-Fernandez, A., Harrington, K., Wood, H. A. C., Chankeshwara, S., Zhu, P., Choudhury, D., Yu, F., Thomson, R., Duncan, R., Dhaliwal, K. & Bradley, M., 19 Apr 2017.

    Research output: Contribution to conferencePaper

  38. Poly(ethylmethacrylate-co-diethylaminoethyl acrylate) coating improves endothelial re-population, bio-mechanical and anti-thrombogenic properties of decellularized carotid arteries for blood vessel replacement

    López-ruiz, E., Venkateswaran, S., Perán, M., Jiménez, G., Pernagallo, S., Díaz-mochón, J. J., Tura-ceide, O., Arrebola, F., Melchor, J., Soto, J., Rus, G., Real, P. J., Diaz-ricart, M., Conde-gonzález, A., Bradley, M. & Marchal, J. A., 24 Mar 2017, In : Scientific Reports. 7, 1

    Research output: Contribution to journalArticle

  39. Synthesis and optimization of a reactive oxygen species responsive cellular delivery system

    Perez-lopez, A. M., Valero, E. & Bradley, M., 1 Feb 2017, In : New journal of chemistry. 41, 6, p. 2392-2400

    Research output: Contribution to journalArticle

  40. Tetrazine-Responsive Self-immolative Linkers

    Neumann, K., Jain, S., Gambardella, A., Walker, S. E., Valero, E., Lilienkampf, A. & Bradley, M., 3 Jan 2017, In : ChemBioChem. 18, 1, p. 91-95

    Research output: Contribution to journalArticle

  41. 2016
  42. Endoscopic sensing of alveolar pH

    Choudhury, D., Tanner, M. G., Mcaughtrie, S., Yu, F., Mills, B., Choudhary, T. R., Seth, S., Craven, T., Stone, J. M., Mati, I. K., Campbell, C. J., Bradley, M., Williams, C. K. I., Dhaliwal, K., Birks, T. A. & Thomson, R. R., 13 Dec 2016, In : Biomedical Optics Express. 8, 1, p. 243

    Research output: Contribution to journalArticle

  43. Copper Catalysis in Living Systems and In Situ Drug Synthesis

    Clavadetscher, J., Hoffmann, S., Lilienkampf, A., Mackay, L., Yusop, R. M., Rider, S. A., Mullins, J. J. & Bradley, M., 12 Dec 2016, In : Angewandte Chemie International Edition. 55, 50, p. 15662-15666

    Research output: Contribution to journalArticle

  44. Synthesis and characterization of biodegradable poly(ether-ester) urethane acrylates for controlled drug release

    Feng, X., Wang, G., Neumann, K., Yao, W., Ding, L., Li, S., Sheng, Y., Jiang, Y., Bradley, M. & Zhang, R., 7 Dec 2016, In : Materials science & engineering. C, Materials for biological applications. 74, p. 270-278 9 p.

    Research output: Contribution to journalArticle

  45. Palladium-mediated in situ synthesis of an anticancer agent

    Indrigo, E., Clavadetscher, J., Chankeshwara, S. V., Lilienkampf, A. & Bradley, M., 25 Nov 2016, In : Chemical Communications. 52, 99, p. 14212-14214

    Research output: Contribution to journalArticle

  46. High-throughput identification of bacteria repellent polymers for medical devices

    Gallagher, M., Gwynne, P., Wu, M., Hardman, A., Lilienkampf, A., Pernagallo, S., Blakely, G., Swann, D. G. & Bradley, M., 5 Nov 2016, In : Journal of Visualized Experiments (JoVE). 117, e54382.

    Research output: Contribution to journalArticle

  47. Understanding Polymer-Cell Attachment

    Venturato, A., Macfarlane, G., Geng, J. & Bradley, M., 25 Oct 2016, In : Macromolecular bioscience.

    Research output: Contribution to journalArticle

  48. Searching for the Optimal Fluorophore to Label Antimicrobial Peptides

    Zhao, C., Fernandez Vargas, A., Avlonitis, N., Vande Velde, G., Bradley, M., Read, N. D. & Vendrell, M., 10 Oct 2016, In : ACS Combinatorial Science.

    Research output: Contribution to journalArticle

  49. Novel bead-based platform for direct detection of unlabelled nucleic acids through Single Nucleobase Labelling

    Venkateswaran, S., Luque-González, M. A., Tabraue-Chávez, M., Fara, M. A., López-Longarela, B., Cano-Cortes, V., López-Delgado, F. J., Sánchez-Martín, R. M., Ilyine, H., Bradley, M., Pernagallo, S. & Díaz-Mochón, J. J., 31 Aug 2016, In : Talanta. 161, p. 489-496 8 p.

    Research output: Contribution to journalArticle

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