Edinburgh Research Explorer

Dr Masoud Shirali

(Former employee or visitor)

Masoud Shirali
Deanery of Clinical Sciences
Centre for Clinical Brain Sciences
Postal address:
7th Floor
Kennedy Tower
Edinburgh Royal Hospital
Morningside Park
Centre for Clinical Brain Sciences
EH10 5HF
Edinburgh
United Kingdom

Projects

LOCATING THE MISSING HERITABILITY OF COMPLEX TRAITS USING REGIONAL HAPLOTYPE MAPPING

Haley, C., Navarro, P., Pong-Wong, R., Shirali, M. & Knott, S.

BBSRC

1/05/1230/04/15

Publications

Haplotype Heritability Mapping Method Uncovers Missing Heritability of Complex Traits

Shirali, M., Knott, S., Pong-Wong, R., Navarro, P. & Haley, C., 21 Mar 2018, In : Scientific Reports. 8, 4982.

Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

Luciano, M., Hagenaars, S., Davies, G., Hill, W. D., Clarke, T-K., Shirali, M., Harris, S., Marioni, R., Liewald, D., Fawns-ritchie, C., Adams, M., Howard, D. M., Lewis, C. M., Gale, C., McIntosh, A. & Deary, I., 18 Dec 2017, In : Nature Genetics. 50, p. 6-11

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

Howard, D. M., Adams, M. J., Shirali, M., Clarke, T-K., Marioni, R., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M., Wigmore, E., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C., Breen, G., Deary, I. & 1 others, McIntosh, A., 16 Apr 2018, In : Nature Communications. 9, 1, p. 1-10 1470.

Regional heritability mapping method helps explain missing heritability of blood lipid traits in isolated populations

Shirali, M., Pong-Wong, R., Navarro, P., Knott, S., Hayward, C., Vitart, V., Rudan, I., Campbell, H., Hastie, N., Wright, A. & Haley, C., Mar 2016, In : Heredity. 116, p. 333–338

Analysis of Blood Lipid Traits Using Regional Heritability Mapping

Shirali, M., Pong-Wong, R., Navarro, P., Hayward, C., Vitart, V., Rudan, I., Campbell, H., Hastie, N., Wright, A. & Haley, C., 2012, p. P279 204.

Genome-wide regional heritability mapping identifies a locus within the TOX2 gene associated with Major Depressive Disorder

Zeng, Y., Navarro, P., Shirali, M., Howard, D., Adams, M., Hall, L., Clarke, T-K., Thomson, P., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B., Milaneschi, Y., Baune, B. T. & 19 others, Air, T., Hottenga, J-J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Deary, I., Porteous, D., Haley, C. & McIntosh, A., 1 Sep 2017, In : Biological Psychiatry. 82, 5, p. 312-321

Using Haplotype Mapping to Uncover the Missing Heritability: A Simulation Study

Shirali, M., Pong-Wong, R., Knott, S., Hayward, C., Vitart, V., Rudan, I., Campbell, H., Hastie, N., Wright, A., Navarro, P. & Haley, C., 2014, (Unpublished) proceedings of the 10th World Congress in Ganetics Applied to Livestock Production.

Comparison between BayesC and GBLUP methods to estimate genomic breeding values in threshold phenotypes

Shirali, M., Miraei-Ashtiani, S. R., Pakdel, A., Haley, C., Navarro, P. & Pong-Wong, R., 2012, In : Advances in Animal Biosciences. 3, 1, p. 131 1 p.

Regional heritability mapping for the dissection of complex traits

Nagamine, Y., Pong-Wong, R., Navarro, P., Shirali, M., Uemoto, Y., Huffman, J., Vitart, V., Hayward, C., Riggio, V., Matika, O., Bishop, S., Rudan, I., Campbell, H., Hastie, N., Wright, A. & Haley, C., 2012, p. P21 74.

Comparison between Bayesc and GBLUP in Estimating Genomic Breeding Values under Different QTL Variance Distributions

Shirali, M., Miraei-Ashtiani, S. R., Pakdel, A., Haley, C. & Pong-Wong, R., 2012, In : Iranian Journal of Animal Science. p. 261-268 8 p.

A Comparison of the Sensitivity of the BayesC and Genomic Best Linear Unbiased Prediction (GBLUP) Methods of Estimating Genomic Breeding Values under Different Quantitative Trait Locus (QTL) Model Assumptions

Shirali, M., Miraei-Ashtiani, S. R., Pakdel, A., Haley, C., Navarro, P. & Pong-Wong, R., Mar 2015, In : Iranian Journal of Applied Animal Science . 5, 1, p. 41-46