Edinburgh Research Explorer

Moira Whyte

Vice-Principal & Head of College of Medicine & Vet Medicine

  1. 2020
  2. Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis

    Sadiku, P., Wilson, J. A., Ryan, E. M., Sammut, D., Dos Santos Coelho, P., Watts, E. R., Grecian, R., Young, J. M., Bewley, M., Arienti, S., Mirchandani, A. S., Sanchez Garcia, M. A., Morrison, T., Zhang, A., Reyes, L., Griessler, T., Jheeta, P., Paterson, G., Graham, C., Thompson, J. P. & 16 others, Baillie, J. K., Thompson, R., Morgan, J. M., Acosta-Sanchez, A., Darde, V. M., Duran, J., Guinovart, J. J., Rodriguez Blanco, G., von Kriegsheim, A., Meehan, R. R., Mazzone, M., Dockrell, D. H., Ghesquiere, B., Carmeliet, P., Whyte, M. K. B. & Walmsley, S. R., 10 Dec 2020, In: Cell Metabolism.

    Research output: Contribution to journalArticlepeer-review

  3. Effect of Co-trimoxazole (Trimethoprim-Sulfamethoxazole) vs Placebo on Death, Lung Transplant, or Hospital Admission in Patients With Moderate and Severe Idiopathic Pulmonary Fibrosis: The EME-TIPAC Randomized Clinical Trial

    Wilson, A. M., Clark, A. B., Cahn, T., Chilvers, E. R., Fraser, W., Hammond, M., Livermore, D. M., Maher, T. M., Parfrey, H., Swart, A. M., Stirling, S., Thickett, D. R. & Whyte, M., 8 Dec 2020, In: Journal of the American Medical Association (JAMA). 324, 22, p. 2282

    Research output: Contribution to journalArticlepeer-review

  4. Semaphorin 3F signaling actively retains neutrophils at sites of inflammation

    Plant, T., Eamsamarng, S., Sanchez-garcia, M. A., Reyes, L., Renshaw, S. A., Coelho, P., Mirchandani, A. S., Morgan, J., Ellett, F. E., Morrison, T., Humphries, D., Watts, E. R., Murphy, F., Raffo-iraolagoitia, X. L., Zhang, A., Cash, J. L., Loynes, C., Elks, P. M., Van Eeden, F., Carlin, L. M. & 3 others, Furley, A. J. W., Whyte, M. K. B. & Walmsley, S. R., 19 Mar 2020, In: Journal of Clinical Investigation.

    Research output: Contribution to journalArticlepeer-review

  5. 2019
  6. A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

    Arnold, N. D., Pickworth, J. A., West, L. E., Dawson, S., Carvalho, J. A., Casbolt, H., Braithwaite, A. T., Iremonger, J., Renshall, L., Germaschewski, V., McCourt, M., Bland-Ward, P., Kowash, H., Hameed, A. G., Rothman, A. M. K., Frid, M. G., Roger Thompson, A. A., Evans, H. R., Southwood, M., Morrell, N. W. & 7 others, Crossman, D. C., Whyte, M. K. B., Stenmark, K. R., Newman, C. M., Kiely, D. G., Francis, S. E. & Lawrie, A., 15 Nov 2019, In: Nature Communications. 10, 1, p. 5183

    Research output: Contribution to journalArticlepeer-review

  7. Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis

    Allen, R. J., Guillen-Guio, B., Oldham, J. M., Ma, S-F., Dressen, A., Paynton, M. L., Kraven, L. M., Obeidat, M., Li, X., Ng, M., Braybrooke, R., Molina-Molina, M., Hobbs, B. D., Putman, R. K., Sakornsakolpat, P., Booth, H. L., Fahy, W. A., Hart, S. P., Hill, M. R., Hirani, N. & 46 others, Hubbard, R. B., McAnulty, R. J., Millar, A. B., Navaratnam, V., Oballa, E., Parfrey, H., Saini, G., Whyte, M. K. B., Zhang, Y., Kaminski, N., Adegunsoye, A., Strek, M. E., Neighbors, M., Sheng, X. R., Gudmundsson, G., Gudnason, V., Hatabu, H., Lederer, D. J., Manichaikul, A., Newell, J. D., O'Connor, G. T., Ortega, V. E., Xu, H., Fingerlin, T. E., Bossé, Y., Hao, K., Joubert, P., Nickle, D. C., Sin, D. D., Timens, W., Furniss, D., Morris, A. P., Zondervan, K., Hall, I. P., Sayers, I., Tobin, M. D., Maher, T. M., Cho, M. H., Hunninghake, G. M., Schwartz, D. A., Yaspan, B. L., Molyneaux, P. L., Flores, C., Noth, I., Jenkins, R. G. & Wain, L. V., 11 Nov 2019, In: American Journal of Respiratory and Critical Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  8. Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation

    Rahman, A., Henry, K. M., Herman, K. D., Thompson, A. A., Isles, H. M., Tulotta, C., Sammut, D., Rougeot, J. J., Khoshaein, N., Reese, A. E., Higgins, K., Tabor, C., Sabroe, I., Zuercher, W. J., Savage, C. O., Meijer, A. H., Whyte, M. K., Dockrell, D. H., Renshaw, S. A. & Prince, L. R., 15 Oct 2019, In: eLIFE. 8

    Research output: Contribution to journalArticlepeer-review

  9. Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages

    COPDMAP consortium, 10 Oct 2019, In: European Respiratory Journal. 54, 4

    Research output: Contribution to journalArticlepeer-review

  10. Alveolar macrophage apoptosis-associated bacterial killing helps prevent murine pneumonia

    Preston, J. A., Bewley, M. A., Marriott, H. M., Houghton, A. M., Mohasin, M., Jubrail, J., Morris, L., Stephenson, Y. L., Cross, S., Greaves, D. R., Craig, R. W., van Rooijen, N., Bingle, C. D., Read, R. C., Mitchell, T. J., Whyte, M. K. B., Shapiro, S. D. & Dockrell, D. H., 1 Jul 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 1, p. 84–97 14 p.

    Research output: Contribution to journalArticlepeer-review

  11. IL4Rα signaling abrogates hypoxic neutrophil survival and limits acute lung injury responses in vivo

    Harris, A. J., Mirchandani, A. S., Lynch, R. W., Murphy, F., Delaney, L., Small, D., Coelho, P., Watts, E. R., Sadiku, P., Griffith, D., Dickinson, R. S., Clark, E., Willson, J. A., Morrison, T., Mazzone, M., Carmeliet, P., Ghesquiere, B., O'Kane, C., McAuley, D., Jenkins, S. J. & 2 others, Whyte, M. K. B. & Walmsley, S. R., 8 Mar 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 2, p. 235–246 12 p.

    Research output: Contribution to journalArticlepeer-review

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