Edinburgh Research Explorer

Moira Whyte

Vice-Principal & Head of College of Medicine & Vet Medicine

  1. A Bayesian approach to copy-number-polymorphism analysis in nuclear pedigrees

    Kosta, K., Sabroe, I., Goeke, J., Nibbs, R. J., Tsanakas, J., Whyte, M. K. & Teare, M. D., Oct 2007, In : American Journal of Human Genetics. 81, 4, p. 808-812 5 p.

    Research output: Contribution to journalArticle

  2. A Cardinal Role for Cathepsin D in Co-Ordinating the Host-Mediated Apoptosis of Macrophages and Killing of Pneumococci

    Bewley, M. A., Marriott, H. M., Tulone, C., Francis, S. E., Mitchell, T. J., Read, R. C., Chain, B., Kroemer, G., Whyte, M. K. B. & Dockrell, D., 27 Jan 2011, In : Plos Pathogens. 7, 1, 17 p., 1001262.

    Research output: Contribution to journalArticle

  3. A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism

    Robertson, A. L., Holmes, G. R., Bojarczuk, A. N., Burgon, J., Loynes, C. A., Chimen, M., Sawtell, A. K., Hamza, B., Willson, J., Walmsley, S. R., Anderson, S. R., Coles, M. C., Farrow, S. N., Solari, R., Jones, S., Prince, L. R., Irimia, D., Rainger, G. E., Kadirkamanathan, V., Whyte, M. K. B. & 1 others, Renshaw, S. A., 26 Feb 2014, In : Science Translational Medicine. 6, 225, 10 p., 225ra29.

    Research output: Contribution to journalArticle

  4. A decoy receptor 3 analogue reduces localised defects in phagocyte function in pneumococcal pneumonia

    Marriott, H. M., Daigneault, M., Thompson, A. A. R., Walmsley, S. R., Gill, S. K., Witcher, D. R., Wroblewski, V. J., Hellewell, P. G., Whyte, M. K. B. & Dockrell, D., Nov 2012, In : Thorax. 67, 11, p. 985-992 8 p.

    Research output: Contribution to journalArticle

  5. A large-scale, consortium-based genomewide association study of asthma

    Moffatt, M. F., Gut, I. G., Demenais, F., Strachan, D. P., Bouzigon, E., Heath, S., von Mutius, E., Farrall, M., Lathrop, M., GABRIEL Consortium, Whyte, M. & Cookson, W. O. C. M., 23 Sep 2010, In : New England Journal of Medicine. 363, 13, p. 1211-21 11 p.

    Research output: Contribution to journalArticle

  6. A local circadian clock calls time on lung inflammation

    Thompson, A. A. R., Walmsley, S. R. & Whyte, M. K. B., Aug 2014, In : Nature Medicine. 20, 8, p. 809-811 3 p.

    Research output: Contribution to journalEditorial

  7. A method for the in vivo measurement of zebrafish tissue neutrophil lifespan

    Dixon, G., Elks, P. M., Loynes, C. A., Whyte, M. K. B. & Renshaw, S. A., 2012, In : ISRN hematology. 2012, 915868.

    Research output: Contribution to journalArticle

  8. A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

    Arnold, N. D., Pickworth, J. A., West, L. E., Dawson, S., Carvalho, J. A., Casbolt, H., Braithwaite, A. T., Iremonger, J., Renshall, L., Germaschewski, V., McCourt, M., Bland-Ward, P., Kowash, H., Hameed, A. G., Rothman, A. M. K., Frid, M. G., Roger Thompson, A. A., Evans, H. R., Southwood, M., Morrell, N. W. & 7 others, Crossman, D. C., Whyte, M. K. B., Stenmark, K. R., Newman, C. M., Kiely, D. G., Francis, S. E. & Lawrie, A., 15 Nov 2019, In : Nature Communications. 10, 1, p. 5183

    Research output: Contribution to journalArticle

  9. Activation of hypoxia-inducible factor-1 alpha (Hif-1 alpha) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model

    Elks, P. M., van Eeden, F. J., Dixon, G., Wang, X., Reyes-Aldasoro, C. C., Ingham, P. W., Whyte, M. K. B., Walmsley, S. R. & Renshaw, S. A., 21 Jul 2011, In : Blood. 118, 3, p. 712-722 11 p.

    Research output: Contribution to journalArticle

  10. Alpha-nicotinic acetylcholine receptor and tobacco smoke exposure: effects on bronchial hyperresponsiveness in children

    Torjussen, T. M., Lødrup Carlsen, K. C., Munthe-Kaas, M. C., Mowinckel, P., Carlsen, K-H., Helms, P. J., Gerritsen, J., Whyte, M. K., Lenney, W., Undlien, D. E., Shianna, K. V., Zhu, G. & Pillai, S. G., Feb 2012, In : Pediatric Allergy and Immunology. 23, 1, p. 40-9 10 p.

    Research output: Contribution to journalArticle

  11. Alveolar Macrophage Apoptosis-Associated Bacterial Killing Helps Prevent Murine Pneumonia

    Preston, J. A., Bewley, M. A., Marriott, H. M., Houghton, A. M., Mohasin, M., Jubrail, J., Morris, L., Stephenson, Y. L., Cross, S., Greaves, D. R., Craig, R. W., van Rooijen, N., Bingle, C. D., Read, R. C., Mitchell, T. J., Whyte, M. K. B., Shapiro, S. D. & Dockrell, D. H., 16 Jan 2019, In : American Journal of Respiratory and Critical Care Medicine.

    Research output: Contribution to journalArticle

  12. Association of PTGDR gene polymorphisms with asthma in two Caucasian populations

    Zhu, G., Vestbo, J., Lenney, W., Silverman, M., Whyte, M., Helms, P., Anderson, W. H. & Pillai, S. G., Jul 2007, In : Genes and Immunity. 8, 5, p. 398-403 6 p.

    Research output: Contribution to journalArticle

  13. Coeliac disease and risk of tuberculosis: a population-based cohort study

    Sanders, D. S., West, J. & Whyte, M. K. B., Jan 2007, In : Thorax. 62, 1, p. 1-2 2 p.

    Research output: Contribution to journalEditorial

  14. Contrasting roles for reactive oxygen species and nitric oxide in the innate response to pulmonary infection with Streptococcus pneumoniae

    Marriott, H. M., Hellewell, P. G., Whyte, M. K. B. & Dockrell, D., 22 Mar 2007, In : Vaccine. 25, 13, p. 2485-2490 6 p.

    Research output: Contribution to journalArticle

  15. Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages

    COPDMAP consortium, 10 Oct 2019, In : European Respiratory Journal. 54, 4

    Research output: Contribution to journalArticle

  16. Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis

    McGrath, E. E., Lawrie, A., Marriott, H. M., Mercer, P., Cross, S. S., Arnold, N., Singleton, V., Thompson, A. A. R., Walmsley, S. R., Renshaw, S. A., Sabroe, I., Chambers, R. C., Dockrell, D. & Whyte, M. K. B., Sep 2012, In : Thorax. 67, 9, p. 796-803 8 p.

    Research output: Contribution to journalArticle

  17. Delayed Neutrophil Apoptosis Enhances NET Formation in Cystic Fibrosis

    Gray, R. D., Hardisty, G., Regan, K. H., Smith, M., Robb, C. T., Duffin, R., Mackellar, A., Felton, J. M., Paemka, L., McCullagh, B. N., Lucas, C. D., David, D., McKone, E. F., Cooke, G., Donnelly, S. C., Singh, P. K., Stoltz, D. A., Haslett, C., McCray, P. B., Whyte, M. K. B. & 2 others, Rossi, A. G. & Davidson, D. J., 15 Sep 2017, In : Thorax.

    Research output: Contribution to journalArticle

  18. Development of a Consensus Statement for the Definition, Diagnosis, and Treatment of Acute Exacerbations of Idiopathic Pulmonary Fibrosis Using the Delphi Technique

    Maher, T. M., Whyte, M. K. B., Hoyles, R. K., Parfrey, H., Ochiai, Y., Mathieson, N., Turnbull, A., Williamson, N. & Bennett, B. M., 23 Oct 2015, In : Journal of cancer research and therapeutics.

    Research output: Contribution to journalArticle

  19. Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD

    Bewley, M. A., Belchamber, K. B. R., Chana, K. K., Budd, R. C., Donaldson, G., Wedzicha, J. A., Brightling, C. E., Kilty, I., Donnelly, L. E., Barnes, P. J., Singh, D., Whyte, M. K. B., Dockrell, D. & COPDMAP, 28 Sep 2016, In : PLoS ONE. 11, 9, p. e0163139

    Research output: Contribution to journalArticle

  20. Distinct Cell Death Programs in Monocytes Regulate Innate Responses Following Challenge with Common Causes of Invasive Bacterial Disease

    Webster, S. J., Daigneault, M., Bewley, M. A., Preston, J. A., Marriott, H. M., Walmsley, S. R., Read, R. C., Whyte, M. K. B. & Dockrell, D., 1 Sep 2010, In : Journal of Immunology. 185, 5, p. 2968-2979 12 p.

    Research output: Contribution to journalArticle

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