Edinburgh Research Explorer

Prof Moira Whyte

Vice-Principal & Head of College of Medicine & Vet Medicine

  1. Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils

    McGovern, N. N., Cowburn, A. S., Porter, L., Walmsley, S. R., Summers, C., Thompson, A. A. R., Anwar, S., Willcocks, L. C., Whyte, M. K. B., Condliffe, A. M. & Chilvers, E. R., Jan 2011, In : Journal of Immunology. 186, 1, p. 453-463 11 p.

    Research output: Contribution to journalArticle

  2. Hypoxia and reprogramming of host pathogen interactions

    Ryan, E. M., Whyte, M. K. & Walmsley, S. R., 27 Nov 2018, In : Current opinion in physiology. 7, p. 15-20

    Research output: Contribution to journalArticle

  3. Hypoxia determines survival outcomes of bacterial infection through HIF-1alpha dependent re-programming of leukocyte metabolism

    Thompson, A. A. R., Dickinson, R., Murphy, F., Thomson, J. P., Marriott, H. M., Tavares, A., Willson, J. A., Williams, L., Lewis, A., Mirchandani, A., Dos Santos Coelho, P., Doherty, C., Ryan, E., Watts, E., Morton, N. M., Forbes, S., Stimson, R. H., Hameed, A. G., Arnold, N., Preston, J. A. & 15 others, Lawrie, A., Finisguerra, V., Mazzone, M., Sadiku, P., Goveia, J., Taverna, F., Carmeliet, P., Foster, S. J., Chilvers, E. R., Cowburn, A. S., Dockrell, D. H., Johnson, R. S., Meehan, R. R., Whyte, M. K. B. & Walmsley, S. R., 10 Feb 2017, In : Science Immunology. 2, 8, eaal2861.

    Research output: Contribution to journalArticle

  4. Hypoxia, the HIF pathway and neutrophilic inflammatory responses

    Thompson, A. A. R., Binham, J., Plant, T., Whyte, M. K. B. & Walmsley, S. R., Apr 2013, In : Biological Chemistry. 394, 4, p. 471-477 7 p.

    Research output: Contribution to journalLiterature review

  5. Hypoxia-inducible factor 2 alpha regulates key neutrophil functions in humans, mice, and zebrafish

    Thompson, A. A. R., Elks, P. M., Marriott, H. M., Eamsamarng, S., Higgins, K. R., Lewis, A., Williams, L., Parmar, S., Shaw, G., McGrath, E. E., Formenti, F., Van Eeden, F. J., Kinnula, V. L., Pugh, C. W., Sabroe, I., Dockrell, D. H., Chilvers, E. R., Robbins, P. A., Percy, M. J., Simon, M. C. & 4 others, Johnson, R. S., Renshaw, S. A., Whyte, M. K. B. & Walmsley, S. R., 16 Jan 2014, In : Blood. 123, 3, p. 366-376 11 p.

    Research output: Contribution to journalArticle

  6. IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo.

    Harris, A. J., Mirchandani, A. S., Lynch, R. W., Murphy, F., Delaney, L., Small, D., Coelho, P., Watts, E. R., Sadiku, P., Griffith, D., Dickinson, R. S., Clark, E., Willson, J. A., Morrison, T., Mazzone, M., Carmeliet, P., Ghesquiere, B., O'kane, C., Mcauley, D., Jenkins, S. J. & 2 others, Whyte, M. K. B. & Walmsley, S. R., 8 Mar 2019, In : American Journal of Respiratory and Critical Care Medicine.

    Research output: Contribution to journalArticle

  7. Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation

    White, J. H., Chiano, M., Wigglesworth, M., Geske, R., Riley, J., White, N., Hall, S., Zhu, G., Maurio, F., Savage, T., Anderson, W., Cordy, J., Ducceschi, M., GAIN investigators, Whyte, M., Vestbo, J. & Pillai, S. G., 1 Jul 2008, In : Human Molecular Genetics. 17, 13, p. 1890-903 14 p.

    Research output: Contribution to journalArticle

  8. Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen

    Robertson, A. L., Ogryzko, N. V., Henry, K. M., Loynes, C. A., Foulkes, M. J., Meloni, M. M., Wang, X., Ford, C., Jackson, M., Ingham, P. W., Wilson, H. L., Farrow, S. N., Solari, R., Flower, R. J., Jones, S., Whyte, M. K. B. & Renshaw, S. A., 14 Apr 2016, In : Disease Models & Mechanisms.

    Research output: Contribution to journalArticle

  9. Idiopathic pulmonary fibrosis

    Hoo, Z. H. & Whyte, M. K. B., Aug 2012, In : Thorax. 67, 8, p. 742-746 5 p.

    Research output: Contribution to journalLiterature review

  10. Impaired mitochondrial microbicidal responses in chronic obstructive pulmonary disease macrophages

    Bewley, M. A., Preston, J. A., Mohasin, M., Marriott, H. M., Budd, R. C., Swales, J., Collini, P., Greaves, D. R., Craig, R. W., Brightling, C. E., Donnelly, L. E., Barnes, P. J., Singh, D., Shapiro, S. D., Whyte, M. K. B. & Dockrell, D. H., 30 May 2017, In : American Journal of Respiratory and Critical Care Medicine.

    Research output: Contribution to journalArticle

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