Edinburgh Research Explorer

Moira Whyte

Vice-Principal & Head of College of Medicine & Vet Medicine

  1. Abstract › Research › Not peer-reviewed
  2. Article › Research › Peer-reviewed
  3. A Bayesian approach to copy-number-polymorphism analysis in nuclear pedigrees

    Kosta, K., Sabroe, I., Goeke, J., Nibbs, R. J., Tsanakas, J., Whyte, M. K. & Teare, M. D., Oct 2007, In: American Journal of Human Genetics. 81, 4, p. 808-812 5 p.

    Research output: Contribution to journalArticlepeer-review

  4. A Cardinal Role for Cathepsin D in Co-Ordinating the Host-Mediated Apoptosis of Macrophages and Killing of Pneumococci

    Bewley, M. A., Marriott, H. M., Tulone, C., Francis, S. E., Mitchell, T. J., Read, R. C., Chain, B., Kroemer, G., Whyte, M. K. B. & Dockrell, D., 27 Jan 2011, In: Plos Pathogens. 7, 1, 17 p., 1001262.

    Research output: Contribution to journalArticlepeer-review

  5. A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism

    Robertson, A. L., Holmes, G. R., Bojarczuk, A. N., Burgon, J., Loynes, C. A., Chimen, M., Sawtell, A. K., Hamza, B., Willson, J., Walmsley, S. R., Anderson, S. R., Coles, M. C., Farrow, S. N., Solari, R., Jones, S., Prince, L. R., Irimia, D., Rainger, G. E., Kadirkamanathan, V., Whyte, M. K. B. & 1 others, Renshaw, S. A., 26 Feb 2014, In: Science Translational Medicine. 6, 225, 10 p., 225ra29.

    Research output: Contribution to journalArticlepeer-review

  6. A decoy receptor 3 analogue reduces localised defects in phagocyte function in pneumococcal pneumonia

    Marriott, H. M., Daigneault, M., Thompson, A. A. R., Walmsley, S. R., Gill, S. K., Witcher, D. R., Wroblewski, V. J., Hellewell, P. G., Whyte, M. K. B. & Dockrell, D., Nov 2012, In: Thorax. 67, 11, p. 985-992 8 p.

    Research output: Contribution to journalArticlepeer-review

  7. A large-scale, consortium-based genomewide association study of asthma

    Moffatt, M. F., Gut, I. G., Demenais, F., Strachan, D. P., Bouzigon, E., Heath, S., von Mutius, E., Farrall, M., Lathrop, M., GABRIEL Consortium, Whyte, M. & Cookson, W. O. C. M., 23 Sep 2010, In: New England Journal of Medicine. 363, 13, p. 1211-21 11 p.

    Research output: Contribution to journalArticlepeer-review

  8. A method for the in vivo measurement of zebrafish tissue neutrophil lifespan

    Dixon, G., Elks, P. M., Loynes, C. A., Whyte, M. K. B. & Renshaw, S. A., 2012, In: ISRN hematology. 2012, 915868.

    Research output: Contribution to journalArticlepeer-review

  9. A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

    Arnold, N. D., Pickworth, J. A., West, L. E., Dawson, S., Carvalho, J. A., Casbolt, H., Braithwaite, A. T., Iremonger, J., Renshall, L., Germaschewski, V., McCourt, M., Bland-Ward, P., Kowash, H., Hameed, A. G., Rothman, A. M. K., Frid, M. G., Roger Thompson, A. A., Evans, H. R., Southwood, M., Morrell, N. W. & 7 others, Crossman, D. C., Whyte, M. K. B., Stenmark, K. R., Newman, C. M., Kiely, D. G., Francis, S. E. & Lawrie, A., 15 Nov 2019, In: Nature Communications. 10, 1, p. 5183

    Research output: Contribution to journalArticlepeer-review

  10. Activation of hypoxia-inducible factor-1 alpha (Hif-1 alpha) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model

    Elks, P. M., van Eeden, F. J., Dixon, G., Wang, X., Reyes-Aldasoro, C. C., Ingham, P. W., Whyte, M. K. B., Walmsley, S. R. & Renshaw, S. A., 21 Jul 2011, In: Blood. 118, 3, p. 712-722 11 p.

    Research output: Contribution to journalArticlepeer-review

  11. Alpha-nicotinic acetylcholine receptor and tobacco smoke exposure: effects on bronchial hyperresponsiveness in children

    Torjussen, T. M., Lødrup Carlsen, K. C., Munthe-Kaas, M. C., Mowinckel, P., Carlsen, K-H., Helms, P. J., Gerritsen, J., Whyte, M. K., Lenney, W., Undlien, D. E., Shianna, K. V., Zhu, G. & Pillai, S. G., Feb 2012, In: Pediatric Allergy and Immunology. 23, 1, p. 40-9 10 p.

    Research output: Contribution to journalArticlepeer-review

  12. Alveolar macrophage apoptosis-associated bacterial killing helps prevent murine pneumonia

    Preston, J. A., Bewley, M. A., Marriott, H. M., Houghton, A. M., Mohasin, M., Jubrail, J., Morris, L., Stephenson, Y. L., Cross, S., Greaves, D. R., Craig, R. W., van Rooijen, N., Bingle, C. D., Read, R. C., Mitchell, T. J., Whyte, M. K. B., Shapiro, S. D. & Dockrell, D. H., 1 Jul 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 1, p. 84–97 14 p.

    Research output: Contribution to journalArticlepeer-review

  13. Association of PTGDR gene polymorphisms with asthma in two Caucasian populations

    Zhu, G., Vestbo, J., Lenney, W., Silverman, M., Whyte, M., Helms, P., Anderson, W. H. & Pillai, S. G., Jul 2007, In: Genes and Immunity. 8, 5, p. 398-403 6 p.

    Research output: Contribution to journalArticlepeer-review

  14. Contrasting roles for reactive oxygen species and nitric oxide in the innate response to pulmonary infection with Streptococcus pneumoniae

    Marriott, H. M., Hellewell, P. G., Whyte, M. K. B. & Dockrell, D., 22 Mar 2007, In: Vaccine. 25, 13, p. 2485-2490 6 p.

    Research output: Contribution to journalArticlepeer-review

  15. Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages

    COPDMAP consortium, 10 Oct 2019, In: European Respiratory Journal. 54, 4

    Research output: Contribution to journalArticlepeer-review

  16. Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis

    McGrath, E. E., Lawrie, A., Marriott, H. M., Mercer, P., Cross, S. S., Arnold, N., Singleton, V., Thompson, A. A. R., Walmsley, S. R., Renshaw, S. A., Sabroe, I., Chambers, R. C., Dockrell, D. & Whyte, M. K. B., Sep 2012, In: Thorax. 67, 9, p. 796-803 8 p.

    Research output: Contribution to journalArticlepeer-review

  17. Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis

    Gray, R. D., Hardisty, G., Regan, K. H., Smith, M., Robb, C. T., Duffin, R., Mackellar, A., Felton, J. M., Paemka, L., McCullagh, B. N., Lucas, C. D., David, D., McKone, E. F., Cooke, G., Donnelly, S. C., Singh, P. K., Stoltz, D. A., Haslett, C., McCray, P. B., Whyte, M. K. B. & 2 others, Rossi, A. G. & Davidson, D. J., Feb 2018, In: Thorax. 73, 2, p. 134-144 11 p.

    Research output: Contribution to journalArticlepeer-review

  18. Development of a Consensus Statement for the Definition, Diagnosis, and Treatment of Acute Exacerbations of Idiopathic Pulmonary Fibrosis Using the Delphi Technique

    Maher, T. M., Whyte, M. K. B., Hoyles, R. K., Parfrey, H., Ochiai, Y., Mathieson, N., Turnbull, A., Williamson, N. & Bennett, B. M., 23 Oct 2015, In: Journal of cancer research and therapeutics.

    Research output: Contribution to journalArticlepeer-review

  19. Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD

    Bewley, M. A., Belchamber, K. B. R., Chana, K. K., Budd, R. C., Donaldson, G., Wedzicha, J. A., Brightling, C. E., Kilty, I., Donnelly, L. E., Barnes, P. J., Singh, D., Whyte, M. K. B., Dockrell, D. & COPDMAP, 28 Sep 2016, In: PLoS ONE. 11, 9, p. e0163139

    Research output: Contribution to journalArticlepeer-review

  20. Distinct Cell Death Programs in Monocytes Regulate Innate Responses Following Challenge with Common Causes of Invasive Bacterial Disease

    Webster, S. J., Daigneault, M., Bewley, M. A., Preston, J. A., Marriott, H. M., Walmsley, S. R., Read, R. C., Whyte, M. K. B. & Dockrell, D., 1 Sep 2010, In: Journal of Immunology. 185, 5, p. 2968-2979 12 p.

    Research output: Contribution to journalArticlepeer-review

  21. Drift-diffusion analysis of neutrophil migration during inflammation resolution in a zebrafish model

    Holmes, G. R., Dixon, G., Anderson, S. R., Reyes-Aldasoro, C. C., Elks, P. M., Billings, S. A., Whyte, M. K. B., Kadirkamanathan, V. & Renshaw, S. A., 17 Aug 2012, In: Advances in Hematology. 2012, 792163.

    Research output: Contribution to journalArticlepeer-review

  22. Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance

    Marriott, H. M., Bingle, C. D., Read, R. C., Braley, K. E., Kroemer, G., Hellewell, P. G., Craig, R. W., Whyte, M. K. B. & Dockrell, D. H., Feb 2005, In: Journal of Clinical Investigation. 115, 2, p. 359-68 10 p.

    Research output: Contribution to journalArticlepeer-review

  23. Effect of Co-trimoxazole (Trimethoprim-Sulfamethoxazole) vs Placebo on Death, Lung Transplant, or Hospital Admission in Patients With Moderate and Severe Idiopathic Pulmonary Fibrosis: The EME-TIPAC Randomized Clinical Trial

    Wilson, A. M., Clark, A. B., Cahn, T., Chilvers, E. R., Fraser, W., Hammond, M., Livermore, D. M., Maher, T. M., Parfrey, H., Swart, A. M., Stirling, S., Thickett, D. R. & Whyte, M., 8 Dec 2020, In: Journal of the American Medical Association (JAMA). 324, 22, p. 2282

    Research output: Contribution to journalArticlepeer-review

  24. Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation

    Wardle, D. J., Burgon, J., Sabroe, I., Bingle, C. D., Whyte, M. K. B. & Renshaw, S. A., 6 Jan 2011, In: PLoS ONE. 6, 1, 7 p., 15768.

    Research output: Contribution to journalArticlepeer-review

  25. Experimental validation of the hyperpolarized (129) Xe chemical shift saturation recovery technique in healthy volunteers and subjects with interstitial lung disease

    Stewart, N. J., Leung, G., Norquay, G., Marshall, H., Parra-Robles, J., Murphy, P. S., Schulte, R. F., Elliot, C., Condliffe, R., Griffiths, P. D., Kiely, D. G., Whyte, M. K., Wolber, J. & Wild, J. M., 8 Aug 2014, In: Magnetic Resonance in Medicine.

    Research output: Contribution to journalArticlepeer-review

  26. Factor analysis in the Genetics of Asthma International Network family study identifies five major quantitative asthma phenotypes

    Pillai, S. G., Tang, Y., van den Oord, E., Klotsman, M., Barnes, K., Carlsen, K., Gerritsen, J., Lenney, W., Silverman, M., Sly, P., Sundy, J., Tsanakas, J., von Berg, A., Whyte, M., Ortega, H. G., Anderson, W. H. & Helms, P. J., Mar 2008, In: Clinical and Experimental Allergy. 38, 3, p. 421-429 9 p.

    Research output: Contribution to journalArticlepeer-review

  27. Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study

    Allen, R. J., Porte, J., Braybrooke, R., Flores, C., Fingerlin, T. E., Oldham, J. M., Guillen-Guio, B., Ma, S-F., Okamoto, T., John, A. E., Obeidat, M., Yang, I. V., Henry, A., Hubbard, R. B., Navaratnam, V., Saini, G., Thompson, N., Booth, H. L., Hart, S. P., Hill, M. R. & 23 others, Hirani, N., Maher, T. M., McAnulty, R. J., Millar, A. B., Molyneaux, P. L., Parfrey, H., Rassl, D. M., Whyte, M. K. B., Fahy, W. A., Marshall, R. P., Oballa, E., Bossé, Y., Nickle, D. C., Sin, D. D., Timens, W., Shrine, N., Sayers, I., Hall, I. P., Noth, I., Schwartz, D. A., Tobin, M. D., Wain, L. V. & Jenkins, R. G., 1 Nov 2017, In: The Lancet Respiratory Medicine. 5, 11, p. 869-880 12 p.

    Research output: Contribution to journalArticlepeer-review

  28. Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis

    Allen, R. J., Guillen-Guio, B., Oldham, J. M., Ma, S-F., Dressen, A., Paynton, M. L., Kraven, L. M., Obeidat, M., Li, X., Ng, M., Braybrooke, R., Molina-Molina, M., Hobbs, B. D., Putman, R. K., Sakornsakolpat, P., Booth, H. L., Fahy, W. A., Hart, S. P., Hill, M. R., Hirani, N. & 46 others, Hubbard, R. B., McAnulty, R. J., Millar, A. B., Navaratnam, V., Oballa, E., Parfrey, H., Saini, G., Whyte, M. K. B., Zhang, Y., Kaminski, N., Adegunsoye, A., Strek, M. E., Neighbors, M., Sheng, X. R., Gudmundsson, G., Gudnason, V., Hatabu, H., Lederer, D. J., Manichaikul, A., Newell, J. D., O'Connor, G. T., Ortega, V. E., Xu, H., Fingerlin, T. E., Bossé, Y., Hao, K., Joubert, P., Nickle, D. C., Sin, D. D., Timens, W., Furniss, D., Morris, A. P., Zondervan, K., Hall, I. P., Sayers, I., Tobin, M. D., Maher, T. M., Cho, M. H., Hunninghake, G. M., Schwartz, D. A., Yaspan, B. L., Molyneaux, P. L., Flores, C., Noth, I., Jenkins, R. G. & Wain, L. V., 11 Nov 2019, In: American Journal of Respiratory and Critical Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  29. Hypoxia Selectively Inhibits Respiratory Burst Activity and Killing of Staphylococcus aureus in Human Neutrophils

    McGovern, N. N., Cowburn, A. S., Porter, L., Walmsley, S. R., Summers, C., Thompson, A. A. R., Anwar, S., Willcocks, L. C., Whyte, M. K. B., Condliffe, A. M. & Chilvers, E. R., Jan 2011, In: Journal of Immunology. 186, 1, p. 453-463 11 p.

    Research output: Contribution to journalArticlepeer-review

  30. Hypoxia and reprogramming of host pathogen interactions

    Ryan, E. M., Whyte, M. K. & Walmsley, S. R., 27 Nov 2018, In: Current opinion in physiology. 7, p. 15-20

    Research output: Contribution to journalArticlepeer-review

  31. Hypoxia determines survival outcomes of bacterial infection through HIF-1alpha dependent re-programming of leukocyte metabolism

    Thompson, A. A. R., Dickinson, R., Murphy, F., Thomson, J. P., Marriott, H. M., Tavares, A., Willson, J. A., Williams, L., Lewis, A., Mirchandani, A., Dos Santos Coelho, P., Doherty, C., Ryan, E., Watts, E., Morton, N. M., Forbes, S., Stimson, R. H., Hameed, A. G., Arnold, N., Preston, J. A. & 15 others, Lawrie, A., Finisguerra, V., Mazzone, M., Sadiku, P., Goveia, J., Taverna, F., Carmeliet, P., Foster, S. J., Chilvers, E. R., Cowburn, A. S., Dockrell, D. H., Johnson, R. S., Meehan, R. R., Whyte, M. K. B. & Walmsley, S. R., 10 Feb 2017, In: Science Immunology. 2, 8, eaal2861.

    Research output: Contribution to journalArticlepeer-review

  32. Hypoxia-inducible factor 2 alpha regulates key neutrophil functions in humans, mice, and zebrafish

    Thompson, A. A. R., Elks, P. M., Marriott, H. M., Eamsamarng, S., Higgins, K. R., Lewis, A., Williams, L., Parmar, S., Shaw, G., McGrath, E. E., Formenti, F., Van Eeden, F. J., Kinnula, V. L., Pugh, C. W., Sabroe, I., Dockrell, D. H., Chilvers, E. R., Robbins, P. A., Percy, M. J., Simon, M. C. & 4 others, Johnson, R. S., Renshaw, S. A., Whyte, M. K. B. & Walmsley, S. R., 16 Jan 2014, In: Blood. 123, 3, p. 366-376 11 p.

    Research output: Contribution to journalArticlepeer-review

  33. IL4Rα signaling abrogates hypoxic neutrophil survival and limits acute lung injury responses in vivo

    Harris, A. J., Mirchandani, A. S., Lynch, R. W., Murphy, F., Delaney, L., Small, D., Coelho, P., Watts, E. R., Sadiku, P., Griffith, D., Dickinson, R. S., Clark, E., Willson, J. A., Morrison, T., Mazzone, M., Carmeliet, P., Ghesquiere, B., O'Kane, C., McAuley, D., Jenkins, S. J. & 2 others, Whyte, M. K. B. & Walmsley, S. R., 8 Mar 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 2, p. 235–246 12 p.

    Research output: Contribution to journalArticlepeer-review

  34. Identification of a novel asthma susceptibility gene on chromosome 1qter and its functional evaluation

    White, J. H., Chiano, M., Wigglesworth, M., Geske, R., Riley, J., White, N., Hall, S., Zhu, G., Maurio, F., Savage, T., Anderson, W., Cordy, J., Ducceschi, M., GAIN investigators, Whyte, M., Vestbo, J. & Pillai, S. G., 1 Jul 2008, In: Human Molecular Genetics. 17, 13, p. 1890-903 14 p.

    Research output: Contribution to journalArticlepeer-review

  35. Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen

    Robertson, A. L., Ogryzko, N. V., Henry, K. M., Loynes, C. A., Foulkes, M. J., Meloni, M. M., Wang, X., Ford, C., Jackson, M., Ingham, P. W., Wilson, H. L., Farrow, S. N., Solari, R., Flower, R. J., Jones, S., Whyte, M. K. B. & Renshaw, S. A., 14 Apr 2016, In: Disease Models & Mechanisms.

    Research output: Contribution to journalArticlepeer-review

  36. Impaired mitochondrial microbicidal responses in chronic obstructive pulmonary disease macrophages

    Bewley, M. A., Preston, J. A., Mohasin, M., Marriott, H. M., Budd, R. C., Swales, J., Collini, P., Greaves, D. R., Craig, R. W., Brightling, C. E., Donnelly, L. E., Barnes, P. J., Singh, D., Shapiro, S. D., Whyte, M. K. B. & Dockrell, D. H., 1 Oct 2017, In: American Journal of Respiratory and Critical Care Medicine. 196, 7, p. 845–855 11 p.

    Research output: Contribution to journalArticlepeer-review

  37. Impairment of apoptotic cell engulfment by pyocyanin, a toxic metabolite of Pseudomonas aeruginosa

    Bianchi, S. M., Prince, L. R., McPhillips, K., Allen, L., Marriott, H. M., Taylor, G. W., Hellewell, P. G., Sabroe, I., Dockrell, D., Henson, P. W. & Whyte, M. K. B., 1 Jan 2008, In: American Journal of Respiratory and Critical Care Medicine. 177, 1, p. 35-43 9 p.

    Research output: Contribution to journalArticlepeer-review

  38. Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation

    Rahman, A., Henry, K. M., Herman, K. D., Thompson, A. A., Isles, H. M., Tulotta, C., Sammut, D., Rougeot, J. J., Khoshaein, N., Reese, A. E., Higgins, K., Tabor, C., Sabroe, I., Zuercher, W. J., Savage, C. O., Meijer, A. H., Whyte, M. K., Dockrell, D. H., Renshaw, S. A. & Prince, L. R., 15 Oct 2019, In: eLIFE. 8

    Research output: Contribution to journalArticlepeer-review

  39. Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y(11) receptor

    Vaughan, K. R., Stokes, L., Prince, L. R., Marriott, H. M., Meis, S., Kassack, M. U., Bingle, C. D., Sabroe, I., Surprenant, A. & Whyte, M. K. B., 15 Dec 2007, In: Journal of Immunology. 179, 12, p. 8544-8553 10 p.

    Research output: Contribution to journalArticlepeer-review

  40. Interleukin 18 receptor 1 gene polymorphisms are associated with asthma

    Zhu, G., Whyte, M. K. B., Vestbo, J., Carlsen, K., Carlsen, K-H., Lenney, W., Silverman, M., Helms, P. & Pillai, S. G., Sep 2008, In: European Journal of Human Genetics. 16, 9, p. 1083-1090 8 p.

    Research output: Contribution to journalArticlepeer-review

  41. Interleukin-1 beta Regulates CXCL8 Release and Influences Disease Outcome in Response to Streptococcus pneumoniae, Defining Intercellular Cooperation between Pulmonary Epithelial Cells and Macrophages

    Marriott, H. M., Gascoyne, K. A., Gowda, R., Geary, I., Nicklin, M. J. H., Iannelli, F., Pozzi, G., Mitchell, T. J., Whyte, M. K. B., Sabroe, I. & Dockrell, D., Mar 2012, In: Infection and Immunity. 80, 3, p. 1140-1149 10 p.

    Research output: Contribution to journalArticlepeer-review

  42. Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society

    Bradley, B., Branley, H. M., Egan, J. J., Greaves, M. S., Hansell, D. M., Harrison, N. K., Hirani, N., Hubbard, R., Lake, F., Millar, A. B., Wallace, W. A. H., Wells, A. U., Whyte, M., Wilsher, M. L. & British Thoracic Society Interstitial Lung Disease Guideline Group, British Thoracic Society Standards of Care Committee, 2008, In: Thorax. 63 Suppl 5, p. v1-58

    Research output: Contribution to journalArticlepeer-review

  43. Loss of the Oxygen Sensor PHD3 Enhances the Innate Immune Response to Abdominal Sepsis

    Kiss, J., Mollenhauer, M., Walmsley, S. R., Kirchberg, J., Radhakrishnan, P., Niemietz, T., Dudda, J., Steinert, G., Whyte, M. K. B., Carmeliet, P., Mazzone, M., Weitz, J. & Schneider, M., 15 Aug 2012, In: Journal of Immunology. 189, 4, p. 1955-1965 11 p.

    Research output: Contribution to journalArticlepeer-review

  44. Macrophage phenotype is associated with disease severity in preterm infants with chronic lung disease

    Prince, L. R., Maxwell, N. C., Gill, S. K., Dockrell, D. H., Sabroe, I., McGreal, E. P., Kotecha, S. & Whyte, M. K., 12 Aug 2014, In: PLoS ONE. 9, 8, p. e103059

    Research output: Contribution to journalArticlepeer-review

  45. Modeling inflammation in the Zebrafish: How a fish can help us understand lung disease

    Renshaw, S. A., Loynes, C. A., Elworthy, S., Ingham, P. W. & Whyte, M. K. B., Dec 2007, In: Experimental Lung Research. 33, 10, p. 549-554 6 p.

    Research output: Contribution to journalArticlepeer-review

  46. Monocytes Regulate the Mechanism of T-cell Death by Inducing Fas-Mediated Apoptosis during Bacterial Infection

    Daigneault, M., De Silva, T. I., Bewley, M. A., Preston, J. A., Marriott, H. M., Mitchell, A. M., Mitchell, T. J., Read, R. C., Whyte, M. K. B. & Dockrell, D., 19 Jul 2012, In: Plos Pathogens. 8, 7, 16 p., 1002814.

    Research output: Contribution to journalArticlepeer-review

  47. Mutations in Succinate Dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1alpha expression

    Jones, R., McDonald, K. E., Willson, J. A., Ghesquiere, B., Sammut, D., Daniel, E., Harris, A. J., Lewis, A., Thompson, A. A. R., Dickinson, R. S., Plant, T., Murphy, F., Sadiku, P., Keevil, B. G., Carmeliet, P., Whyte, M. K. B., Newell-Price, J. & Walmsley, S. R., 26 May 2016, In: Blood. 127, 21, p. 2641-2644 4 p.

    Research output: Contribution to journalArticlepeer-review

  48. NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival

    Prince, L. R., Dannewitz Prosseda, S., Higgins, K., Carlring, J., Prestwich, E. C., Ogryzko, N. V., Rahman, A., Basran, A., Falciani, F., Taylor, P., Renshaw, S. A., Whyte, M. K. B. & Sabroe, I., 21 Jun 2017, In: Blood.

    Research output: Contribution to journalArticlepeer-review

  49. Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis

    Walmsley, S. R., Cowburn, A. S., Clatworthy, M. R., Morrell, N. W., Roper, E. C., Singleton, V., Maxwell, P., Whyte, M. K. B. & Chilvers, E. R., 1 Nov 2006, In: Blood. 108, 9, p. 3176-3178 3 p.

    Research output: Contribution to journalArticlepeer-review

  50. Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis

    Sadiku, P., Wilson, J. A., Ryan, E. M., Sammut, D., Dos Santos Coelho, P., Watts, E. R., Grecian, R., Young, J. M., Bewley, M., Arienti, S., Mirchandani, A. S., Sanchez Garcia, M. A., Morrison, T., Zhang, A., Reyes, L., Griessler, T., Jheeta, P., Paterson, G., Graham, C., Thompson, J. P. & 16 others, Baillie, J. K., Thompson, R., Morgan, J. M., Acosta-Sanchez, A., Darde, V. M., Duran, J., Guinovart, J. J., Rodriguez Blanco, G., von Kriegsheim, A., Meehan, R. R., Mazzone, M., Dockrell, D. H., Ghesquiere, B., Carmeliet, P., Whyte, M. K. B. & Walmsley, S. R., 10 Dec 2020, In: Cell Metabolism.

    Research output: Contribution to journalArticlepeer-review

  51. Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease is Enhanced by Nrf2 Agonists

    Bewley, M. A., Budd, R. C., Ryan, E., Cole, J., Collini, P., Marshall, J., Kolsum, U., Beech, G., Emes, R. D., Tcherniaeva, I., Berbers, G. A. M., Walmsley, S. R., Donaldson, G., Wedzicha, J. A., Kilty, I., Rumsey, W., Sanchez, Y., Brightling, C. E., Donnelly, L. E., Barnes, P. J. & 4 others, Singh, D., Whyte, M. K. B., Dockrell, D. H. & COPDMAP, 15 Sep 2018, In: American Journal of Respiratory and Critical Care Medicine. 198, 6, p. 739-750 12 p.

    Research output: Contribution to journalArticlepeer-review

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