Edinburgh Research Explorer

Prof Moira Whyte

Vice-Principal & Head of College of Medicine & Vet Medicine

  1. 2017
  2. Hypoxia determines survival outcomes of bacterial infection through HIF-1alpha dependent re-programming of leukocyte metabolism

    Thompson, A. A. R., Dickinson, R., Murphy, F., Thomson, J. P., Marriott, H. M., Tavares, A., Willson, J. A., Williams, L., Lewis, A., Mirchandani Thanwerdas, A., Dos Santos Coelho, P., Doherty, C., Ryan, E., Watts, E., Morton, N., Stimson, R., Hameed, A. G., Arnold, N., Preston, J. A., Lawrie, A. & 15 others, Finisguerra, V., Mazzone, M., Sadiku, P., Goveia, J., Taverna, F., Carmeliet, P., Foster, S. J., Chilvers, E. R., Cowburn, A. S., Dockrell, D. H., Johnson, R. S., Meehan, R., Whyte, M., Walmsley, S. & Forbes, S., 10 Feb 2017, In : Science Immunology. 2, 8, eaal2861.

    Research output: Contribution to journalArticle

  3. 2016
  4. Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD

    Bewley, M. A., Belchamber, K. B. R., Chana, K. K., Budd, R. C., Donaldson, G., Wedzicha, J. A., Brightling, C. E., Kilty, I., Donnelly, L. E., Barnes, P. J., Singh, D., Whyte, M. K. B., Dockrell, D. & COPDMAP, 28 Sep 2016, In : PLoS ONE. 11, 9, p. e0163139

    Research output: Contribution to journalArticle

  5. Mutations in Succinate Dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1alpha expression

    Jones, R., McDonald, K. E., Willson, J. A., Ghesquiere, B., Sammut, D., Daniel, E., Harris, A., Lewis, A., Thompson, A. A. R., Dickinson, R., Plant, T., Murphy, F., Sadiku, P., Keevil, B. G., Carmeliet, P., Whyte, M., Newell-Price, J. & Walmsley, S., 26 May 2016, In : Blood.

    Research output: Contribution to journalArticle

  6. Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen

    Robertson, A. L., Ogryzko, N., Henry, K. M., Loynes, C. A., Foulkes, M. J., Meloni, M. M., Wang, X., Ford, C., Jackson, M., Ingham, P. W., Wilson, H. L., Farrow, S. N., Solari, R., Flower, R. J., Jones, S., Whyte, M. K. B. & Renshaw, S. A., 14 Apr 2016, In : Disease Models & Mechanisms.

    Research output: Contribution to journalArticle

  7. 2015
  8. Development of a Consensus Statement for the Definition, Diagnosis, and Treatment of Acute Exacerbations of Idiopathic Pulmonary Fibrosis Using the Delphi Technique

    Maher, T. M., Whyte, M. K. B., Hoyles, R. K., Parfrey, H., Ochiai, Y., Mathieson, N., Turnbull, A., Williamson, N. & Bennett, B. M., 23 Oct 2015, In : Journal of cancer research and therapeutics.

    Research output: Contribution to journalArticle

  9. 2014
  10. Pneumolysin Activates Macrophage Lysosomal Membrane Permeabilization and Executes Apoptosis by Distinct Mechanisms without Membrane Pore Formation

    Bewley, M. A., Naughton, M., Preston, J., Mitchell, A., Holmes, A., Marriott, H. M., Read, R. C., Mitchell, T. J., Whyte, M. K. B. & Dockrell, D., 7 Oct 2014, In : mBio. 5, 5

    Research output: Contribution to journalArticle

  11. Macrophage phenotype is associated with disease severity in preterm infants with chronic lung disease

    Prince, L. R., Maxwell, N. C., Gill, S. K., Dockrell, D., Sabroe, I., McGreal, E. P., Kotecha, S. & Whyte, M. K., 12 Aug 2014, In : PLoS ONE. 9, 8, p. e103059

    Research output: Contribution to journalArticle

  12. Experimental validation of the hyperpolarized (129) Xe chemical shift saturation recovery technique in healthy volunteers and subjects with interstitial lung disease

    Stewart, N. J., Leung, G., Norquay, G., Marshall, H., Parra-Robles, J., Murphy, P. S., Schulte, R. F., Elliot, C., Condliffe, R., Griffiths, P. D., Kiely, D. G., Whyte, M. K., Wolber, J. & Wild, J. M., 8 Aug 2014, In : Magnetic Resonance in Medicine.

    Research output: Contribution to journalArticle

  13. A local circadian clock calls time on lung inflammation

    Thompson, A. A. R., Walmsley, S. R. & Whyte, M. K. B., Aug 2014, In : Nature Medicine. 20, 8, p. 809-811 3 p.

    Research output: Contribution to journalEditorial

  14. Neutrophil energetics and oxygen sensing

    Walmsley, S. R. & Whyte, M. K. B., 1 May 2014, In : Blood. 123, 18, p. 2753-2754 4 p.

    Research output: Contribution to journalEditorial

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