Edinburgh Research Explorer

Moira Whyte

Vice-Principal & Head of College of Medicine & Vet Medicine

  1. 2017
  2. Impaired mitochondrial microbicidal responses in chronic obstructive pulmonary disease macrophages

    Bewley, M. A., Preston, J. A., Mohasin, M., Marriott, H. M., Budd, R. C., Swales, J., Collini, P., Greaves, D. R., Craig, R. W., Brightling, C. E., Donnelly, L. E., Barnes, P. J., Singh, D., Shapiro, S. D., Whyte, M. K. B. & Dockrell, D. H., 1 Oct 2017, In: American Journal of Respiratory and Critical Care Medicine. 196, 7, p. 845–855 11 p.

    Research output: Contribution to journalArticlepeer-review

  3. Phd2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

    Sadiku, P., Willson, J. A., Dickinson, R., Murphy, F., Harris, A., Lewis, A., Sammut, D., Mirchandani, A. S., Ryan, E., Watts, E. R., Thompson, A. A. R., Marriott, H. M., Dockrell, D. H., Taylor, C. T., Schneider, M., Maxwell, P. H., Chilvers, E. R., Mazzone, M., Moral, V., Pugh, C. W. & 6 others, Ratcliffe, P. J., Schofield, C. J., Ghesquiere, B., Carmeliet, P., Whyte, M. K. B. & Walmsley, S. R., 1 Sep 2017, In: Journal of Clinical Investigation. 127, 9, p. 3407-3420 14 p.

    Research output: Contribution to journalArticlepeer-review

  4. The identification of Staphylococcus aureus factors required for pathogenicity and growth in human blood

    Connolly, J., Boldock, E., Prince, L. R., Renshaw, S. A., Whyte, M. K. & Foster, S. J., 14 Aug 2017, In: Infection and Immunity.

    Research output: Contribution to journalArticlepeer-review

  5. NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival

    Prince, L. R., Dannewitz Prosseda, S., Higgins, K., Carlring, J., Prestwich, E. C., Ogryzko, N. V., Rahman, A., Basran, A., Falciani, F., Taylor, P., Renshaw, S. A., Whyte, M. K. B. & Sabroe, I., 21 Jun 2017, In: Blood.

    Research output: Contribution to journalArticlepeer-review

  6. Hypoxia determines survival outcomes of bacterial infection through HIF-1alpha dependent re-programming of leukocyte metabolism

    Thompson, A. A. R., Dickinson, R., Murphy, F., Thomson, J. P., Marriott, H. M., Tavares, A., Willson, J. A., Williams, L., Lewis, A., Mirchandani, A., Dos Santos Coelho, P., Doherty, C., Ryan, E., Watts, E., Morton, N. M., Forbes, S., Stimson, R. H., Hameed, A. G., Arnold, N., Preston, J. A. & 15 others, Lawrie, A., Finisguerra, V., Mazzone, M., Sadiku, P., Goveia, J., Taverna, F., Carmeliet, P., Foster, S. J., Chilvers, E. R., Cowburn, A. S., Dockrell, D. H., Johnson, R. S., Meehan, R. R., Whyte, M. K. B. & Walmsley, S. R., 10 Feb 2017, In: Science Immunology. 2, 8, eaal2861.

    Research output: Contribution to journalArticlepeer-review

  7. 2016
  8. Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD

    Bewley, M. A., Belchamber, K. B. R., Chana, K. K., Budd, R. C., Donaldson, G., Wedzicha, J. A., Brightling, C. E., Kilty, I., Donnelly, L. E., Barnes, P. J., Singh, D., Whyte, M. K. B., Dockrell, D. & COPDMAP, 28 Sep 2016, In: PLoS ONE. 11, 9, p. e0163139

    Research output: Contribution to journalArticlepeer-review

  9. Mutations in Succinate Dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1alpha expression

    Jones, R., McDonald, K. E., Willson, J. A., Ghesquiere, B., Sammut, D., Daniel, E., Harris, A. J., Lewis, A., Thompson, A. A. R., Dickinson, R. S., Plant, T., Murphy, F., Sadiku, P., Keevil, B. G., Carmeliet, P., Whyte, M. K. B., Newell-Price, J. & Walmsley, S. R., 26 May 2016, In: Blood. 127, 21, p. 2641-2644 4 p.

    Research output: Contribution to journalArticlepeer-review

  10. Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen

    Robertson, A. L., Ogryzko, N. V., Henry, K. M., Loynes, C. A., Foulkes, M. J., Meloni, M. M., Wang, X., Ford, C., Jackson, M., Ingham, P. W., Wilson, H. L., Farrow, S. N., Solari, R., Flower, R. J., Jones, S., Whyte, M. K. B. & Renshaw, S. A., 14 Apr 2016, In: Disease Models & Mechanisms.

    Research output: Contribution to journalArticlepeer-review

  11. 2015
  12. Development of a Consensus Statement for the Definition, Diagnosis, and Treatment of Acute Exacerbations of Idiopathic Pulmonary Fibrosis Using the Delphi Technique

    Maher, T. M., Whyte, M. K. B., Hoyles, R. K., Parfrey, H., Ochiai, Y., Mathieson, N., Turnbull, A., Williamson, N. & Bennett, B. M., 23 Oct 2015, In: Journal of cancer research and therapeutics.

    Research output: Contribution to journalArticlepeer-review

  13. 2014
  14. Pneumolysin Activates Macrophage Lysosomal Membrane Permeabilization and Executes Apoptosis by Distinct Mechanisms without Membrane Pore Formation

    Bewley, M. A., Naughton, M., Preston, J., Mitchell, A., Holmes, A., Marriott, H. M., Read, R. C., Mitchell, T. J., Whyte, M. K. B. & Dockrell, D. H., 7 Oct 2014, In: mBio. 5, 5

    Research output: Contribution to journalArticlepeer-review

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