Edinburgh Research Explorer

Moira Whyte

Vice-Principal & Head of College of Medicine & Vet Medicine

  1. 2020
  2. Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis

    Sadiku, P., Wilson, J. A., Ryan, E. M., Sammut, D., Dos Santos Coelho, P., Watts, E. R., Grecian, R., Young, J. M., Bewley, M., Arienti, S., Mirchandani, A. S., Sanchez Garcia, M. A., Morrison, T., Zhang, A., Reyes, L., Griessler, T., Jheeta, P., Paterson, G., Graham, C., Thompson, J. P. & 16 others, Baillie, J. K., Thompson, R., Morgan, J. M., Acosta-Sanchez, A., Darde, V. M., Duran, J., Guinovart, J. J., Rodriguez Blanco, G., von Kriegsheim, A., Meehan, R. R., Mazzone, M., Dockrell, D. H., Ghesquiere, B., Carmeliet, P., Whyte, M. K. B. & Walmsley, S. R., 10 Dec 2020, In: Cell Metabolism.

    Research output: Contribution to journalArticlepeer-review

  3. Effect of Co-trimoxazole (Trimethoprim-Sulfamethoxazole) vs Placebo on Death, Lung Transplant, or Hospital Admission in Patients With Moderate and Severe Idiopathic Pulmonary Fibrosis: The EME-TIPAC Randomized Clinical Trial

    Wilson, A. M., Clark, A. B., Cahn, T., Chilvers, E. R., Fraser, W., Hammond, M., Livermore, D. M., Maher, T. M., Parfrey, H., Swart, A. M., Stirling, S., Thickett, D. R. & Whyte, M., 8 Dec 2020, In: Journal of the American Medical Association (JAMA). 324, 22, p. 2282

    Research output: Contribution to journalArticlepeer-review

  4. Semaphorin 3F signaling actively retains neutrophils at sites of inflammation

    Plant, T., Eamsamarng, S., Sanchez-garcia, M. A., Reyes, L., Renshaw, S. A., Coelho, P., Mirchandani, A. S., Morgan, J., Ellett, F. E., Morrison, T., Humphries, D., Watts, E. R., Murphy, F., Raffo-iraolagoitia, X. L., Zhang, A., Cash, J. L., Loynes, C., Elks, P. M., Van Eeden, F., Carlin, L. M. & 3 others, Furley, A. J. W., Whyte, M. K. B. & Walmsley, S. R., 19 Mar 2020, In: Journal of Clinical Investigation.

    Research output: Contribution to journalArticlepeer-review

  5. 2019
  6. A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

    Arnold, N. D., Pickworth, J. A., West, L. E., Dawson, S., Carvalho, J. A., Casbolt, H., Braithwaite, A. T., Iremonger, J., Renshall, L., Germaschewski, V., McCourt, M., Bland-Ward, P., Kowash, H., Hameed, A. G., Rothman, A. M. K., Frid, M. G., Roger Thompson, A. A., Evans, H. R., Southwood, M., Morrell, N. W. & 7 others, Crossman, D. C., Whyte, M. K. B., Stenmark, K. R., Newman, C. M., Kiely, D. G., Francis, S. E. & Lawrie, A., 15 Nov 2019, In: Nature Communications. 10, 1, p. 5183

    Research output: Contribution to journalArticlepeer-review

  7. Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis

    Allen, R. J., Guillen-Guio, B., Oldham, J. M., Ma, S-F., Dressen, A., Paynton, M. L., Kraven, L. M., Obeidat, M., Li, X., Ng, M., Braybrooke, R., Molina-Molina, M., Hobbs, B. D., Putman, R. K., Sakornsakolpat, P., Booth, H. L., Fahy, W. A., Hart, S. P., Hill, M. R., Hirani, N. & 46 others, Hubbard, R. B., McAnulty, R. J., Millar, A. B., Navaratnam, V., Oballa, E., Parfrey, H., Saini, G., Whyte, M. K. B., Zhang, Y., Kaminski, N., Adegunsoye, A., Strek, M. E., Neighbors, M., Sheng, X. R., Gudmundsson, G., Gudnason, V., Hatabu, H., Lederer, D. J., Manichaikul, A., Newell, J. D., O'Connor, G. T., Ortega, V. E., Xu, H., Fingerlin, T. E., Bossé, Y., Hao, K., Joubert, P., Nickle, D. C., Sin, D. D., Timens, W., Furniss, D., Morris, A. P., Zondervan, K., Hall, I. P., Sayers, I., Tobin, M. D., Maher, T. M., Cho, M. H., Hunninghake, G. M., Schwartz, D. A., Yaspan, B. L., Molyneaux, P. L., Flores, C., Noth, I., Jenkins, R. G. & Wain, L. V., 11 Nov 2019, In: American Journal of Respiratory and Critical Care Medicine.

    Research output: Contribution to journalArticlepeer-review

  8. Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation

    Rahman, A., Henry, K. M., Herman, K. D., Thompson, A. A., Isles, H. M., Tulotta, C., Sammut, D., Rougeot, J. J., Khoshaein, N., Reese, A. E., Higgins, K., Tabor, C., Sabroe, I., Zuercher, W. J., Savage, C. O., Meijer, A. H., Whyte, M. K., Dockrell, D. H., Renshaw, S. A. & Prince, L. R., 15 Oct 2019, In: eLIFE. 8

    Research output: Contribution to journalArticlepeer-review

  9. Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages

    COPDMAP consortium, 10 Oct 2019, In: European Respiratory Journal. 54, 4

    Research output: Contribution to journalArticlepeer-review

  10. Alveolar macrophage apoptosis-associated bacterial killing helps prevent murine pneumonia

    Preston, J. A., Bewley, M. A., Marriott, H. M., Houghton, A. M., Mohasin, M., Jubrail, J., Morris, L., Stephenson, Y. L., Cross, S., Greaves, D. R., Craig, R. W., van Rooijen, N., Bingle, C. D., Read, R. C., Mitchell, T. J., Whyte, M. K. B., Shapiro, S. D. & Dockrell, D. H., 1 Jul 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 1, p. 84–97 14 p.

    Research output: Contribution to journalArticlepeer-review

  11. IL4Rα signaling abrogates hypoxic neutrophil survival and limits acute lung injury responses in vivo

    Harris, A. J., Mirchandani, A. S., Lynch, R. W., Murphy, F., Delaney, L., Small, D., Coelho, P., Watts, E. R., Sadiku, P., Griffith, D., Dickinson, R. S., Clark, E., Willson, J. A., Morrison, T., Mazzone, M., Carmeliet, P., Ghesquiere, B., O'Kane, C., McAuley, D., Jenkins, S. J. & 2 others, Whyte, M. K. B. & Walmsley, S. R., 8 Mar 2019, In: American Journal of Respiratory and Critical Care Medicine. 200, 2, p. 235–246 12 p.

    Research output: Contribution to journalArticlepeer-review

  12. 2018
  13. RESPIRE: The National Institute for Health Research's (NIHR) Global Respiratory Health Unit

    Sheikh, A., Campbell, H., Balharry, D., Baqui, A. H., Bogaert, D., Cresswell, K., Cunningham, S., Dockerell, D., El Arifeen, S., Fletcher, M., Grant, M., Shariff Ghazali, S., Habib, G. M. M., Hazir, T., Isaac, R., Juvekar, S., Khoo, E. M., McKinstry, B., Morris, A., Nair, H. & 17 others, Norrie, J., Nwaru, B., Pinnock, H., Robertson, D., Saha, S. K., Salvi, S., Schwarze, J., Simpson, C., Sridhar, D., Stoddart, A., Weller, D., Whyte, M., Worth, A., Williams, S., Yusuf, O., Zumla, A. & Rudan, I., Dec 2018, In: Journal of Global Health. 8, 2, p. 020314

    Research output: Contribution to journalEditorialpeer-review

  14. Hypoxia and reprogramming of host pathogen interactions

    Ryan, E. M., Whyte, M. K. & Walmsley, S. R., 27 Nov 2018, In: Current opinion in physiology. 7, p. 15-20

    Research output: Contribution to journalArticlepeer-review

  15. Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease is Enhanced by Nrf2 Agonists

    Bewley, M. A., Budd, R. C., Ryan, E., Cole, J., Collini, P., Marshall, J., Kolsum, U., Beech, G., Emes, R. D., Tcherniaeva, I., Berbers, G. A. M., Walmsley, S. R., Donaldson, G., Wedzicha, J. A., Kilty, I., Rumsey, W., Sanchez, Y., Brightling, C. E., Donnelly, L. E., Barnes, P. J. & 4 others, Singh, D., Whyte, M. K. B., Dockrell, D. H. & COPDMAP, 15 Sep 2018, In: American Journal of Respiratory and Critical Care Medicine. 198, 6, p. 739-750 12 p.

    Research output: Contribution to journalArticlepeer-review

  16. PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo

    Loynes, C. A., Lee, J. A., Robertson, A. L., Steel, M. J. G., Ellett, F., Feng, Y., Levy, B. D., Whyte, M. & Renshaw, S. A., 5 Sep 2018, In: Science Advances.

    Research output: Contribution to journalArticlepeer-review

  17. The role of neutrophils in cancer

    Grecian, R., Whyte, M. & Walmsley, S., 22 Aug 2018, In: British Medical Bulletin.

    Research output: Contribution to journalArticlepeer-review

  18. The Efficacy and Mechanism Evaluation of Treating Idiopathic Pulmonary fibrosis with the Addition of Co-trimoxazole (EME-TIPAC): study protocol for a randomised controlled trial

    Hammond, M., Clark, A. B., Cahn, A. P., Chilvers, E. R., Fraser, W. D., Livermore, D. M., Maher, T. M., Parfrey, H., Swart, A. M., Stirling, S., Thickett, D. R., Whyte, M. & Wilson, A., 5 Feb 2018, In: Trials. 19, 1, p. 89

    Research output: Contribution to journalArticlepeer-review

  19. Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis

    Gray, R. D., Hardisty, G., Regan, K. H., Smith, M., Robb, C. T., Duffin, R., Mackellar, A., Felton, J. M., Paemka, L., McCullagh, B. N., Lucas, C. D., David, D., McKone, E. F., Cooke, G., Donnelly, S. C., Singh, P. K., Stoltz, D. A., Haslett, C., McCray, P. B., Whyte, M. K. B. & 2 others, Rossi, A. G. & Davidson, D. J., Feb 2018, In: Thorax. 73, 2, p. 134-144 11 p.

    Research output: Contribution to journalArticlepeer-review

  20. 2017
  21. Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study

    Allen, R. J., Porte, J., Braybrooke, R., Flores, C., Fingerlin, T. E., Oldham, J. M., Guillen-Guio, B., Ma, S-F., Okamoto, T., John, A. E., Obeidat, M., Yang, I. V., Henry, A., Hubbard, R. B., Navaratnam, V., Saini, G., Thompson, N., Booth, H. L., Hart, S. P., Hill, M. R. & 23 others, Hirani, N., Maher, T. M., McAnulty, R. J., Millar, A. B., Molyneaux, P. L., Parfrey, H., Rassl, D. M., Whyte, M. K. B., Fahy, W. A., Marshall, R. P., Oballa, E., Bossé, Y., Nickle, D. C., Sin, D. D., Timens, W., Shrine, N., Sayers, I., Hall, I. P., Noth, I., Schwartz, D. A., Tobin, M. D., Wain, L. V. & Jenkins, R. G., 1 Nov 2017, In: The Lancet Respiratory Medicine. 5, 11, p. 869-880 12 p.

    Research output: Contribution to journalArticlepeer-review

  22. Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo

    Dickinson, R. S., Murphy, F., Doherty, C., Williams, S., Mirchandani, A., Willson, J. A., Scotti, J. S., Preston, G., Schofield, C. J., Whyte, M. K. B. & Walmsley, S. R., 26 Oct 2017, In: Wellcome Open Research . 2, p. 104

    Research output: Contribution to journalArticlepeer-review

Previous 1 2 3 4 5 Next