Edinburgh Research Explorer

Dr. Peter Flatman

(Former employee or visitor)

Education/Academic qualification

1974Doctor of Philosophy (PhD)
1974Master of Arts, Univ Cambridge
1971Bachelor of Arts, Univ Cambridge

Biography

Peter Flatman graduated from Cambridge University in 1974 with a 1st class honours degree in Physiology. He remained at the Physiological Laboratory Cambridge to complete an MRC-funded PhD studentship followed by a Research Assistantship under the supervision of Virgilio Lew. In 1980 Peter was appointed to a Lectureship in the Department of Physiology at Edinburgh University. He was promoted to Senior Lecturer in 1991. He spent a sabbatical in 1994 with Peter Lauf and Norma Adragna at Wright State University (Dayton Ohio). In 2004 he became a member of the Centre of Integrative Physiology. He is currently Director of Quality (teaching) in the Deanery of Biomedical Sciences.

Research Interests

The regulation of membrane transport systems particularly by phosphorylation.

My research in a nutshell

Defects in a family of salt transporting proteins and their regulation lie at the heart of many blood pressure problems - we explore the behaviour of these transporters and their control by a network of regulatory proteins to guide more effective treatments that could be tuned to a patient’s specific genetic profile. We take an integrative approach and are particularly interested in the cation-chloride-cotransporters (Slc12) which play major roles in reabsorbing salt in the kidney, regulating sodium levels in vascular smooth muscle, and sensing body sodium levels, together with the families of kinases (SPAK, WNK) that regulate their activity.

Teaching

My teaching encompasses: membrane and transport physiology, body fluids and renal physiology.

Undergraduate

Year 2: Biomedical Sciences 2

Year 3: Biomedical Sciences 3, Physiology 3

Year 4: Integrative Physiology, Physiology 4 (project), Pharmacology 4 (project), Medical Biology 4 (project)

Administrative Roles

Director of Quality: Deanery of Biomedical Sciences

ID: 6108