Edinburgh Research Explorer

Peter Sandercock

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Peter Sandercock

Biography

Professor Peter Sandercock is an academic clinical neurologist at the University of Edinburgh. His chief research interests are in evaluating interventions for the treatment, prevention or rehabilitation of stroke in clinical trials and with systematic reviews of clinical trials.  He was the Chief Investigator of IST-1, the first mega-trial in acute ischaemic stroke, of aspirin & heparin  in 19435 patients with acute stroke recruited from 467 hospitals in 37 countries.  He was Coordinating Editor of the Cochrane Stroke Group 1998-2011.  He is the Co-Chief Investigator of IST-3, the largest-ever trial of thrombolytic therapy for acute ischaemic stroke, with 3035 patients.  His main activities now relate to the design, conduct and oversight of clinical trials.  

Qualifications

Doctor of Medicine, University of Oxford

Award Date: 1 Jan 1985

Bachelor of Medicine, University of Oxford

Award Date: 1 Jan 1972

… → 2001 Fellow of the Academy of Medical Sciences, FMedSci
… → 1991 Fellow of the Royal College of Physicians Edinburgh, FRCPE
… → 1978 Member of the College of Physicians, MRCP
… → 1975 BM BCh

Research output

Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: A community-based inception cohort study

Lothian Audit of the Treatment of Cerebral Haemorrhage (LATCH) collaborators, 25 Nov 2020, In : International Journal of Stroke. p. 174749302097428

Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial

Brenner, A., Belli, A., Chaudhri, R., Coats, T., Frimley, L., Jamaluddin, S. F., Jooma, R., Mansukhani, R., Sandercock, P., Shakur-Still, H., Shokunbi, T. & Roberts, I., 11 Nov 2020, In : Critical Care.

The association between CT biomarkers of cerebral small vessel diseases and long‐term outcome after spontaneous intracerebral hemorrhage

Lothian Audit of the Treatment of Cerebral Haemorrhage (LATCH) collaborators, 3 Nov 2020, In : Annals of Neurology.

Feasibility and diagnostic accuracy of using brain attenuation changes on CT to estimate time of ischemic stroke onset

Mair, G., Alzahrani, A., Lindley, R. I., Sandercock, P. A. G. & Wardlaw, J. M., 30 Oct 2020, In : Neuroradiology.

Top 10 global educational topics in stroke: A survey by the World Stroke Organization

Saini, M., Belson, S., Lahiff-jenkins, C. & Sandercock, P., 10 Jun 2020, In : International Journal of Stroke. 14, 8, p. 843-849

Fluoxetine to improve functional outcomes in patients after acute stroke: the FOCUS RCT

Dennis, M., Forbes, J., Graham, C., Hackett, M. L., Hankey, G. J., House, A., Lewis, S., Lundström, E., Sandercock, P. & Mead, G., 26 May 2020, In : Health Technology Assessment. 24, 22, p. 1-94

In Memoriam Eivind Berge, MD, PhD, 1964–2020

Sandercock, P., Van Der Worp, B. & Sandset, E. C., 20 Apr 2020

Improving Clinical Detection of Acute Lacunar Stroke: Analysis From the IST-3

Arba, F., Mair, G., Phillips, S., Sandercock, P. & Wardlaw, J. M., 9 Apr 2020, In : Stroke.

Eivind Berge, MD, PhD, 1964–2020: Cardiologist Who Was Fighting Stroke

Kjeldsen, S. E., Halvorsen, S., Wyller, T. B., Bath, P. M. & Sandercock, P., 23 Mar 2020, In : Stroke.

Conceptual framework for establishing the African Stroke Organization

Akinyemi, R., Sarfo, F., Abd-allah, F., Ogun, Y., Belo, M., Francis, P., Mateus, M. B., Bateman, K., Naidoo, P., Charway-felli, A., Akpalu, A., Wahab, K., Napon, C., Arulogun, O., Ebenezer, A. A., Ekeng, G., Scola, G., Hamzat, K., Zimba, S., Ossou-nguiet, P. M. & 22 others, Ademokoya, J., Adebayo, P., Ayele, B. A., Vaz, D. C., Ogbole, G., Barasukan, P., Melifonwu, R., Onwuekwe, I., Belson, S., Damasceno, A., Okubadejo, N., Njamnshi, A. K., Ogeng’o, J., Walker, R. W., Diop, A. G., Ogunniyi, A., Kalaria, R., Sandercock, P., Davis, S., Brainin, M., Ovbiagele, B. & Owolabi, M., 6 Feb 2020, In : International Journal of Stroke. p. 174749301989787

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial

The CRASH-3 trial collaborators, 14 Oct 2019, In : The Lancet. 394, 10210, p. 1713-1723

How can the World Stroke Organization (WSO) optimize education in stroke medicine around the world? Report of the 2018 WSO Global Stroke Stakeholder Workshop

Gubitz, G., Saini, M., Belson, S., Sahathevan, R. & Sandercock, P., 10 Sep 2019, In : International Journal of Stroke.

Fluoxetine and Fractures After Stroke: Exploratory Analyses From the FOCUS Trial

Dennis, M., Forbes, J., Graham, C., Hackett, M. L., Hankey, G. J., House, A., Lewis, S., Lundström, E., Sandercock, P. & Mead, G., 20 Aug 2019, In : Stroke.

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Al-Shahi Salman, R., Minks, D. P., Mitra, D., Rodrigues, M. A., Bhatnagar, P., du Plessis, J. C., Joshi, Y., Dennis, M. S., Murray, G. D., Newby, D. E., Sandercock, P. A. G., Sprigg, N., Stephen, J., Sudlow, C. L. M., Werring, D. J., Whiteley, W. N., Wardlaw, J. M., White, P. M. & RESTART collaboration, 1 Jul 2019, In : Lancet Neurology. 18, 7, p. 643-652 10 p.

The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: statistical analysis plan for a randomised controlled trial

Al-Shahi Salman, R., Murray, G. D., Dennis, M. S., Newby, D. E., Sandercock, P. A. G., Sprigg, N., Sudlow, C. L. M., Werring, D. J., White, P. M. & Whiteley, W. N., 25 Mar 2019, In : Trials. 20, 1, p. 183

Clinical diagnosis of TIA or minor stroke and prognosis in patients with neurological symptoms: A rapid access clinic cohort

Sudlow, C., Graham, C., Bailey, D., Hart, S., Hutchison, A., Sandercock, P., Doubal, F., Farrall, A., Wardlaw, J., Dennis, M. & Whiteley, W., 19 Mar 2019, In : PLoS ONE. 14, 3, e0210452.

Stroke in China: advances and challenges in epidemiology, prevention, and management

China Stroke Study Collaboration, 14 Mar 2019, In : Lancet Neurology. 18, 4, p. 394-405

Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial

The RIGHT-2 Investigators, 6 Feb 2019, In : The Lancet.

Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial

FOCUS Trial Collaboration, 19 Jan 2019, In : The Lancet. 398, 10168, p. 265-274 10 p.

World Stroke Day – a day of global action

Sandercock, P., 29 Oct 2018, In : Stroke.

Effect of IV alteplase on the ischemic brain lesion at 24-48 hours after ischemic stroke

IST-3 Collaborative Group, Mair, G., von Kummer, R., Morris, Z., von Heijne, A., Bradey, N., Cala, L., Peeters, A., Farrall, A., Adami, A., Potter, G., Sandercock, P., Lindley, R. I. & Wardlaw, J., 26 Oct 2018, In : Neurology.

Cut stroke in half: Polypill for primary prevention in stroke

Brainin, M., Feigin, V., Martins, S., Matz, K., Roy, J., Sandercock, P., Teuschl, Y., Tuomilehto, J. & Wiseman, A., Aug 2018, In : International Journal of Stroke. 13, 6, p. 174749301876119

Visual rating scales of white matter hyperintensities and atrophy: comparison of computed tomography and magnetic resonance imaging

Ferguson, K., Cvoro, V., Maclullich, A., Shenkin, S., Sandercock, P., Sakka, E. & Wardlaw, J., 23 Mar 2018, In : Journal of Stroke and Cerebrovascular Diseases.

The REstart or STop Antithrombotics Randomised Trial (RESTART) after stroke due to intracerebral haemorrhage: study protocol for a randomised controlled trial

Al-Shahi Salman, R., Dennis, M. S., Murray, G. D., Innes, K., Drever, J., Dinsmore, L., Williams, C., White, P. M., Whiteley, W. N., Sandercock, P. A. G., Sudlow, C. L. M., Newby, D. E., Sprigg, N., Werring, D. J. & RESTART collaborators, 5 Mar 2018, In : Trials. 19, 1, p. 162

How to do high quality clinical research 1: first steps

Sandercock, P. & Whiteley, W., 4 Jan 2018, In : International Journal of Stroke.

Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: Individual-patient-data meta-analysis of randomized trials

Hacke, W., Lyden, P., Emberson, J., Baigent, C., Blackwell, L., Albers, G. W., Bluhmki, E., Brott, T. G., Cohen, G. R., Davis, S. M., Donnan, G. A., Grotta, J. C., Howard, G., Kaste, M., Koga, M., von Kummer, R., Lansberg, M. G., Lindley, R. I., Olivot, J. M., Parsons, M. & 8 others, Sandercock, P., Toni, D., Toyoda, K., Wahlgren, N., Wardlaw, J., Whiteley, W., del Zoppo, G. J. & Lees, K. R., 24 Nov 2017, In : International Journal of Stroke.

Blood pressure variability and leukoaraiosis in acute ischemic stroke

Dickie, D. A., Aribisala, B., Mair, G., Berge, E., Lindley, R. I., Sandercock, P., von Kummer, R., von Heijne, A., Peeters, A., Cala, L., Farrall, A., Morris, Z., Bradey, N., Potter, G., Adami, A. & Wardlaw, J., 5 Sep 2017, In : International Journal of Stroke.

Controversies in Thrombolysis

Sandercock, P. & Ricci, S., 30 Jun 2017, In : Current Neurology and Neuroscience Reports.

Increasing value and reducing waste in stroke research

Berge, E., Salman, R. A. S., van der Worp, H. B., Stapf, C., Sandercock, P., Sprigg, N., Macleod, M. R., Kelly, P. J., Nederkoorn, P. J., Ford, G. A., Arnold, M., Berge, E., Diez-Tejedor, E., Jatuzis, D., Kelly, P. J., Krieger, D. W., Nederkoorn, P. J., Stapf, C., Weimar, C. & Ford, G. A., 1 May 2017, In : Lancet Neurology. 16, 5, p. 399-408 10 p.

Feasibility of using brain attenuation changes on CT to accurately predict time of ischaemic stroke onset

Mair, G., Sandercock, P. & Wardlaw, J., May 2017.

Low-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke

Sandercock, P. A. G. & Leong, T. S., 4 Apr 2017, In : Cochrane Database of Systematic Reviews. 4, 59 p., 000119.

Cerebral white matter hypoperfusion increases with small vessel disease burden. Data from the IST-3 trial

Arba, F., Mair, G., Carpenter, T., Sakka, E., Sandercock, P., Lindley, R., Inzitari, D. & Wardlaw, J., 15 Mar 2017, In : Journal of Stroke and Cerebrovascular Diseases.

Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke

Mair, G., von Kummer, R., Adami, A., White, P. M., Adams, M. E., Yan, B., Demchuk, A. M., Farrall, A. J., Sellar, R. J., Sakka, E., Palmer, J., Perry, D., Lindley, R. I., Sandercock, P. A. G., Wardlaw, J. M. & IST-3 Collaborative Group, 1 Feb 2017, In : Stroke. 48, 2, p. 353-360

Developing an integrated image bank and metadata for large scale research in cerebrovascular disease: our experience from the Stroke Image Bank Project

Danso, S., Wardlaw, J., Sandercock, P., Job, D., Dickie, D. A., Rodriguez Gonzalez, D., Palmer, J. & Bath, P., 26 Dec 2016, In : Frontiers in ICT. 3, 32.

Mortality after thrombolysis – Authors’ reply

Berge, E., Cohen, G. R., Whiteley, W., Wardlaw, J. & Sandercock, P., 1 Dec 2016, In : Lancet Neurology.

Effect of Right Insular Involvement on Death and Functional Outcome after Acute Ischemic Stroke in the IST-3 Trial

Sposato, L. A., Cohen, G., Wardlaw, J. M., Sandercock, P., Lindley, R. I., Hachinski, V., IST-3 Expert Reading Panel & IST-3 Collaborative Grp, Dec 2016, In : Stroke. 47, 12, p. 2959-2965 7 p.

Interpretation of the evidence for the efficacy and safety of statin therapy

Collins, R., Reith, C., Emberson, J., Armitage, J., Baigent, C., Blackwell, L., Blumenthal, R., Danesh, J., Smith, G. D., DeMets, D., Evans, S., Law, M., MacMahon, S., Martin, S., Neal, B., Poulter, N., Preiss, D., Ridker, P., Roberts, I., Rodgers, A. & 8 others, Sandercock, P., Schulz, K., Sever, P., Simes, J., Smeeth, L., Wald, N., Yusuf, S. & Peto, R., 8 Sep 2016, In : The Lancet.

Effects of alteplase for acute stroke on the distribution of functional outcomes: a pooled analysis of nine trials

Lees, K. R., Emberson, J., Blackwell, L., Bluhmki, E., Davis, S., Donnan, G. A., Grotta, J. C., Kaste, M., von Kummer, R., Lansberg, M. G., Lindley, R., Lyden, P., Murray, G., Sandercock, P., Toni, D., Toyoda, K., Wardlaw, J., Whiteley, W., Baigent, C., Hacke, W. & 1 others, Howard, G., 9 Aug 2016, In : Stroke.

Effects of alteplase on survival after ischaemic stroke (IST-3): 3 year follow-up of a randomised, controlled, open-label trial

Berge, E., Cohen, G., Roaldsen, M. B., Lundstrom, E., Isaksson, E., Rudberg, A-S., Slot, K. B., Forbes, J., Smith, J. W. S., Drever, J., Wardlaw, J., Lindley, R. I., Sandercock, P. & Whiteley, W., 19 Jul 2016, In : Lancet Neurology.

The forecast for future clinical trials and clinical trialists - storms or sunshine?

Sandercock, P. & Klijn, C. J. M., 17 Jun 2016, In : International Journal of Stroke.

Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis

Whiteley, W. N., Emberson, J., Lees, K. R., Blackwell, L., Albers, G., Bluhmki, E., Brott, T., Cohen, G., Davis, S., Donnan, G., Grotta, J., Howard, G., Kaste, M., Koga, M., von Kummer, R., Lansberg, M. G., Lindley, R. I., Lyden, P., Olivot, J. M., Parsons, M. & 8 others, Toni, D., Toyoda, K., Wahlgren, N., Wardlaw, J., del Zoppo, G. J., Sandercock, P., Hacke, W. & Baigent, C., 8 Jun 2016, In : Lancet Neurology.

IST-3 stroke trial data available

Sandercock, P., Wardlaw, J., Lindley, R., Whiteley, W. & Cohen, G., 7 May 2016, In : The Lancet. 387, 10031

Visual Scoring Versus Computational Volume Measures of Perfusion Defects In Acute Ischaemic Stroke

Mair, G., Carpenter, T., Cohen, G., Lindley, R., Sandercock, P. & Wardlaw, J., May 2016, p. 458. 1 p.

Methods to improve patient recruitment and retention in stroke trials

Berge, E., Stapf, C., Al-Shahi Salman, R., Ford, G. A., Sandercock, P., van der Worp, H. B., Petersson, J., Dippel, D. W., Krieger, D. W., Lees, K. R. & ESO Trials Network Committee, 26 Apr 2016, In : International Journal of Stroke.

European Stroke Organisation (ESO) guidelines for prophylaxis for venous thromboembolism in immobile patients with acute ischaemic stroke

For the European Stroke Organisation, 1 Mar 2016, In : European Stroke Journal. 1, 1, p. 6-19

Effect of alteplase on the CT hyperdense artery sign and functional outcome after ischemic stroke

Mair, G., von Kummer, R., Morris, Z., von Heijne, A., Bradey, N., Cala, L., Peeters, A., Farrall, A., Adami, A., Potter, G., Cohen, G., Sandercock, P., Lindley, R., Wardlaw, J. & IST-3 Collaborative Group, 12 Jan 2016, In : Neurology. 86, p. 1-8

Exploring the role and function of trial steering committees: results of an expert panel meeting

Harman, N. L., Conroy, E. J., Lewis, S. C., Murray, G., Norrie, J., Sydes, M. R., Lane, J. A., Altman, D. G., Baigent, C., Bliss, J. M., Campbell, M. K., Elbourne, D., Evans, S., Sandercock, P. & Gamble, C., 30 Dec 2015, In : Trials. 16, 1, p. 597

Effect of X-Ray Attenuation of Arterial Obstructions on Intravenous Thrombolysis and Outcome after Ischemic Stroke

Mair, G., von Kummer, R., Lindley, R., Sandercock, P., Wardlaw, J. & IST-3 Collaborative Group, 23 Dec 2015, In : PLoS ONE. 10, e0145683.

Effects of blood pressure and blood pressure-lowering treatment during the first 24 hours among patients in the Third International Stroke Trial of thrombolytic treatment for acute ischemic stroke

Berge, E., Cohen, G., Lindley, R., Sandercock, P., Wardlaw, J., Sandset, E. C. & Whiteley, W., 20 Oct 2015, In : Stroke. 46, 12, p. 3362-3369 8 p.

Does personalized medicine exist and can you test it in a clinical trial?

Sandercock, P. A. G., Oct 2015, In : International Journal of Stroke. 10, 7, p. 994-999 6 p.

Review and prioritization of stroke research recommendations to address the mission of the World Stroke Organization: a call to action from the WSO Research Committee

Sacco, R. L., Sandercock, P., Endres, M., Feigin, V., Pandian, J., Shinohara, Y. & Spence, J. D., Oct 2015, In : International Journal of Stroke. 10, p. 4-9 6 p.

Which stroke patients gain most from intermittent pneumatic compression: further analyses of the CLOTS 3 trial

Dennis, M., Graham, C., Smith, J., Forbes, J., Sandercock, P. & CLOTS trial collaboration, Oct 2015, In : International Journal of Stroke. 10, Supplement A100, p. 103–107

The Clots in Legs Or sTockings after Stroke (CLOTS) 3 trial: a randomised controlled trial to determine whether or not intermittent pneumatic compression reduces the risk of post-stroke deep vein thrombosis and to estimate its cost-effectiveness

Dennis, M., Sandercock, P., Graham, C., Forbes, J. & CLOTS Clots Legs Stockings Stroke, Sep 2015, In : Health Technology Assessment. 19, 76, p. 1-+ 86 p.

Protocol for the perfusion and angiography imaging sub-study of the Third International Stroke Trial (IST-3) of alteplase treatment within six-hours of acute ischemic stroke

Wardlaw, J. M., von Kummer, R., Carpenter, T., Parsons, M., Lindley, R. I., Cohen, G., Murray, V., Kobayashi, A., Peeters, A., Chappell, F. & Sandercock, P. A. G., Aug 2015, In : International Journal of Stroke. 10, 6, p. 956-968

ABCD2 score and secondary stroke prevention. Meta-analysis and effect per 1000 patients triaged

Wardlaw, J., Brazzelli, M., Chappell, F., Miranda, H., Shuler, K., Sandercock, P. & Dennis, M., 28 Jul 2015, In : Neurology. 85, p. 1-8

A call to revolutionise acute stroke care and research

Sandercock, P. A. G., Jul 2015, In : Lancet Neurology. 14, 7, p. 674-675 2 p.

Effect of intravenous recombinant tissue-type plasminogen activator in patients with mild stroke in the Third International Stroke Trial-3: post hoc analysis

Khatri, P., Tayama, D., Cohen, G., Lindley, R., Wardlaw, J., Yeatts, SD., Broderick, JP. & Sandercock, P., 23 Jun 2015, In : Stroke.

Short History of Confidence Intervals Or, Don't Ask "Does the Treatment Work?" but "How Sure Are You That It Works?"

Sandercock, P. A. G., 23 Jun 2015, In : Stroke. 46, 8, p. E184-E187 4 p.

Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform

Treweek, S., Altman, D. G., Bower, P., Campbell, M., Chalmers, I., Cotton, S., Craig, P., Crosby, D., Davidson, P., Devane, D., Duley, L., Dunn, J., Elbourne, D., Farrell, B., Gamble, C., Gillies, K., Hood, K., Lang, T., Littleford, R., Loudon, K. & 11 others, McDonald, A., McPherson, G., Nelson, A., Norrie, J., Ramsay, C., Sandercock, P., Shanahan, D. R., Summerskill, W., Sydes, M., Williamson, P. & Clarke, M., 5 Jun 2015, In : Trials. 16, 1, 9 p., 261.

Veronica Murray MD, PhD, 1949-2014: Specialist in Internal Medicine and Senior Scientist, Karolinska Institutet, Danderyd Hospital, Stockholm Obituary

Sandercock, P., Jun 2015, In : International Journal of Stroke. 10, 4, p. 464-464 1 p.

Association between brain imaging signs, early and late outcomes, and response to intravenous alteplase after acute ischaemic stroke in the third International Stroke Trial (IST-3): secondary analysis of a randomised controlled trial

Wardlaw, J. M., Sandercock, P., Cohen, G., Farrall, A., Lindley, R. I., von Kummer, R., von Heijne, A., Bradey, N., Peeters, A., Cala, L., Adami, A., Morris, Z., Potter, G., Murray, G., Whiteley, W., Perry, D. & Sakka, E., May 2015, In : Lancet Neurology. 14, 5, p. 485-496 12 p.

Targeting aspirin in acute disabling ischemic stroke: an individual patient data meta-analysis of three large randomized trials

Thompson, D. D., Murray, G. D., Candelise, L., Chen, Z., Sandercock, P. A. G. & Whiteley, W. N., 12 Apr 2015, In : International Journal of Stroke.

Thrombolysis in acute stroke Reply

Emberson, J., Lees, K. R., Lyden, P., Baigent, C., Sandercock, P., Hacke, W. & Stroke Treatment Trialists' Collab, 11 Apr 2015, In : The Lancet. 385, 9976, p. 1396-1396 1 p.

Anticoagulants for acute ischaemic stroke

Sandercock, P. A. G., Counsell, C. & Kane, E. J., 12 Mar 2015, In : Cochrane Database of Systematic Reviews. 3, p. CD000024

Alteplase for Acute Ischemic Stroke: Outcomes by Clinically Important Subgroups in the Third International Stroke Trial

Lindley, R. I., Wardlaw, J. M., Whiteley, W. N., Cohen, G., Blackwell, L., Murray, G. D., Sandercock, P. A. G., on behalf of the IST-3 Collaborative Group, Sellar, R. & Farrall, A., Mar 2015, In : Stroke. 46, 3, p. 746-756 11 p.

Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial

The IST-3 Collaborative Group , Jan 2015, In : Neuroradiology. 57, 1, p. 1-9 9 p.

Sensitivity and specificity of the Hyperdense Artery Sign for arterial obstruction in acute ischemic stroke

Mair, G., Boyd, E., Chappell, F., von Kummer, R., Lindley, R., Sandercock, P., Wardlaw, J. & IST-3 Collaborative Group, Jan 2015, In : Stroke. 46, 1, p. 102-107 6 p.

Effect of Alteplase Within 6 Hours of Acute Ischemic Stroke on All-Cause Mortality (Third International Stroke Trial)

Whiteley, W. N., Thompson, D., Murray, G., Cohen, G., Lindley, R. I., Wardlaw, J., Sandercock, P. & IST-3 Collaborative Grp, Dec 2014, In : Stroke. 45, 12, p. 3612-3617 6 p.

Effect of intermittent pneumatic compression on disability, living circumstances, quality of life, and hospital costs after stroke: secondary analyses from CLOTS 3, a randomised trial

Dennis, M., Graham, C., Smith, J., Forbes, J., Sandercock, P., CLOTS Clots Legs sTockings Stroke & Murray, G., Dec 2014, In : Lancet Neurology. 13, 12, p. 1186-1192 7 p.

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

Emberson, J., Lees, K. R., Lyden, P., Blackwell, L., Albers, G., Bluhmki, E., Brott, T., Cohen, G., Davis, S., Donnan, G., Grotta, J., Howard, G., Kaste, M., Koga, M., von Kummer, R., Lansberg, M., Lindley, R. I., Murray, G., Olivot, J. M., Parsons, M. & 11 others, Tilley, B., Toni, D., Toyoda, K., Wahlgren, N., Wardlaw, J., Whiteley, W., Del Zoppo, G. J., Baigent, C., Sandercock, P., Hacke, W. & for the Stroke Thrombolysis Trialists' Collaborative Group, 29 Nov 2014, In : The Lancet. 384, 9958, p. 1929-1935

Alteplase for ischaemic stroke--responses

Sandercock, P., Lindley, R., Wardlaw, J. M., Murray, G., Whiteley, W. & Cohen, G., 23 Aug 2014, In : The Lancet. 384, 9944, p. 660-1 2 p.

Response to Letter Regarding Article, "Targeting Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Based on Risk of Intracranial Hemorrhage or Poor Functional Outcome: An Analysis of the Third International Stroke Trial"

Whiteley, W. N., Thompson, D. & Sandercock, P., Jul 2014, In : Stroke. 45, 7, p. E133-E133 1 p.

An assessment of the cost-effectiveness of magnetic resonance, including diffusion-weighted imaging, in patients with transient ischaemic attack and minor stroke: a systematic review, meta-analysis and economic evaluation

Wardlaw, J., Brazzelli, M., Miranda, H., Chappell, F., McNamee, P., Scotland, G., Quayyum, Z., Martin, D., Shuler, K., Sandercock, P. & Dennis, M., Apr 2014, In : Health Technology Assessment. 18, 27, p. 1-368, v-vi

Is the 'liberation procedure' for multiple sclerosis really liberating?

Hankey, G. J., Sandercock, P., Cantisani, T. A. & Celani, M. G., Apr 2014, In : Journal of Neurology, Neurosurgery & Psychiatry. 85, 4, p. 362-362 1 p.

Length of carotid stenosis predicts peri-procedural stroke or death and restenosis in patients randomized to endovascular treatment or endarterectomy

Bonati, L. H., Ederle, J., Dobson, J., Engelter, S., Featherstone, R. L., Gaines, P. A., Beard, J. D., Venables, G. S., Markus, H. S., Clifton, A., Sandercock, P., Brown, M. M., CAVATAS Investigators & Sellar, R., Apr 2014, In : International Journal of Stroke. 9, 3, p. 297-305 9 p.

Targeting Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Based on Risk of Intracranial Hemorrhage or Poor Functional Outcome An Analysis of the Third International Stroke Trial

Whiteley, W. N., Thompson, D., Murray, G., Cohen, G., Lindley, R. I., Wardlaw, J., Sandercock, P. & IST-3 Collaborat Grp, Apr 2014, In : Stroke. 45, 4, p. 1000-1006 7 p.

Oral antiplatelet therapy for acute ischaemic stroke

Sandercock, P. A., Counsell, C., Tseng, M. & Cecconi, E., 24 Mar 2014, In : Cochrane Database of Systematic Reviews.

Diffusion-weighted imaging and diagnosis of transient ischaemic attack

Brazzelli, M., Chappell, F. M., Miranda, H., Shuler, K., Dennis, M., Sandercock, P. A. G., Muir, K. & Wardlaw, J. M., 2014, In : Annals of Neurology. 75, p. 67-76

Functional status three months after the first ischemic stroke is associated with long-term outcome: data from a community-based cohort

Magalhães, R., Abreu, P., Correia, M., Whiteley, W., Silva, M. C. & Sandercock, P., 2014, In : Cerebrovascular diseases (Basel, Switzerland). 38, 1, p. 46-54 9 p.

Imaging perfusion deficits, arterial patency and thrombolysis safety and efficacy in acute ischaemic stroke. An observational study of the effect of advanced imaging methods in The Third International Stroke Trial (IST-3), a randomised controlled trial

Wardlaw, J., Carpenter, T., Sakka, E., Mair, G., Cohen, G., Shuler, K., Palmer, J. & Sandercock, P., 2014, In : Efficacy and Mechanism Evaluation. 1, p. 1-116

Location, extent and persistence of hyperdense arteries affects outcome in acute ischemic stroke

Mair, G., von Kummer, R., Morris, Z., von Heijne, A., Bradey, N., Cala, L., Peeters, A., Farrall, A., Adami, A., Potter, G., Cohen, G., Sandercock, P., Lindley, R. & Wardlaw, J., 2014, In : Circulation.

Response to thrombolysis treatment in ischemic stroke patients with and without arterial occlusion on computed tomographic angiography: the Third International Stroke Trial.

Mair, G., Wardlaw, J., von Kummer, R. & Sandercock, P., 2014, In : Stroke. 45, Suppl 1, Abst.A6.

Authors' reply

Dennis, M., Sandercock, P., Murray, G. & Forbes, J., 6 Nov 2013, In : The Lancet. 382, 9903, p. 1481-1482 2 p.

Intermittent pneumatic compression in patients with stroke - authors' reply

Dennis, M., Sandercock, P., Murray, G. & Forbes, J., 2 Nov 2013, In : The Lancet. 382, 9903, p. 1481-2 2 p.

Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial

Dennis, M., Sandercock, P., Reid, J., Graham, C., Forbes, J., Murray, G., CLOTS (Clots in Legs Or sTockings after Stroke) Trials Collaboration & Lewis, S., 10 Aug 2013, In : The Lancet. 382, 9891, p. 516-524 9 p.

Effect of thrombolysis with alteplase within 6 h of acute ischaemic stroke on long-term outcomes (the third International Stroke Trial [IST-3]): 18-month follow-up of a randomised controlled trial

Wardlaw, J., Dennis, M., Cohen, G., Murray, G., Innes, K., Whiteley, W., Lindley, R., Venables, G., Czlonkowska, A., Kobayashi, A., Ricci, S., Murray, V., Berge, E., Bruins Slot, K., Hankey, G., Correia, M., Peeters, A., Matz, K., Lyrer, P., Gubitz, G. & 3 others, Phillips, S. J., Arauz, A. & IST-3 Collaborative Group, 1 Aug 2013, In : Lancet Neurology. 12, 8, p. 768-776

Details of a prospective protocol for a collaborative meta-analysis of individual participant data from all randomized trials of intravenous rt-PA vs. control: statistical analysis plan for the Stroke Thrombolysis Trialists' Collaborative meta-analysis

Stroke Thrombolysis Trialists' Collaborative Group, Emberson, J., Lees, K. R., Howard, G., Bluhmki, E., Tiley, B., Albers, G. W., Baigent, C., Blackwell, L., Davis, S. M., Donnan, G. A., Grotto, J., Hacke, W., Kaste, M., von Kummer, R., Lansberg, M. G., Lindley, R., Sandercock, P., Toni, D., Wahlgren, N. & 3 others, Wardlaw, J., Whiteley, W. & del Zoppo, G. J., Jun 2013, In : International Journal of Stroke. 8, 4, p. 278-83 6 p.

Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials

Whiteley, W. N., Adams, H. P., Bath, P. M., Berge, E., Sandset, P. M., Dennis, M., Murray, G. D., Wong, K-S. L. & Sandercock, P. A., Jun 2013, In : Lancet Neurology. 12, 6, p. 539-545 7 p.

The Effect of Graduated Compression Stockings on Long-term Outcomes After Stroke The CLOTS Trials 1 and 2: the CLOTS trials 1 and 2

Dennis, M., Sandercock, P., Reid, J., Graham, C., Murray, G., Venables, G., Rudd, A., Bowler, G., CLOTS Trials Collaboration & Cranswick, G., Apr 2013, In : Stroke. 44, 4, p. 1075-1079 5 p.

Why Calls for More Routine Carotid Stenting Are Currently Inappropriate An International, Multispecialty, Expert Review and Position Statement

Abbott, A. L., Adelman, M. A., Alexandrov, A. V., Barber, P. A., Barnett, H. J. M., Beard, J., Bell, P., Bjorck, M., Blacker, D., Bonati, L. H., Brown, M. M., Buckley, C. J., Cambria, R. P., Castaldo, J. E., Comerota, A. J., Connolly, E. S., Dalman, R. L., Davies, A. H., Eckstein, H-H., Faruqi, R. & 31 others, Feasby, T. E., Fraedrich, G., Gloviczki, P., Hankey, G. J., Harbaugh, R. E., Heldenberg, E., Hennerici, M. G., Hill, M. D., Kleinig, T. J., Mikhailidis, D. P., Moore, W. S., Naylor, R., Nicolaides, A., Paraskevas, K. I., Pelz, D. M., Prichard, J. W., Purdie, G., Ricco, J-B., Ringleb, P. A., Riles, T., Rothwell, P. M., Sandercock, P., Sillesen, H., Spence, J. D., Spinelli, F., Sturm, J., Tan, A., Thapar, A., Veith, F. J., Wijeratne, T. & Zhou, W., Apr 2013, In : Stroke. 44, 4, p. 1186-1190 5 p.

Does intermittent pneumatic compression reduce the risk of post stroke deep vein thrombosis? The CLOTS 3 trial: statistical analysis plan

Dennis, M., Sandercock, P., Murray, G., Forbes, J. & CLOTS Trials Collaboration, 6 Mar 2013, In : Trials. 14, 1, 66.

Association of non-contrast CT and CT angiography with baseline clinical deficit and functional outcome. Substudy analysis of imaging from the Third International Stroke Trial (IST-3)

Mair, G., Wardlaw, J. M., Sandercock, P., Lindley, R., von Kummer, R., Farrall, A. J. & IST-3 Collaborative Grp, 2013, In : Cerebrovascular diseases. 35, p. 405-405 1 p.

Clinical and imaging services for TIA and minor stroke: results of two surveys of practice across the UK

Brazzelli, M., Shuler, K., Quayyum, Z., Hadley, D., Muir, K., McNamee, P., De Wilde, J., Dennis, M., Sandercock, P. & Wardlaw, J. M., 2013, In : BMJ Open. 3, 8

Combining CT angiography with non-contrast CT to predict infarct on follow up CT in acute ischaemic stroke. Substudy analysis of imaging from the Third International Stroke Trial (IST-3)

Mair, G., Wardlaw, J. M., Sandercock, P., Lindley, R., von Kummer, R. & IST-3 Collaborative Grp, 2013, In : Cerebrovascular diseases. 35, p. 237-237 1 p.

Medical image management for multicentre trials. Experience from the Third International Stroke Trial (IST-3) with 6576 scans

Sakka, E., Perry, D., Buchanan, D., Innes, K., Drever, J., Sandercock, P., Lindley, R. L. & Wardlaw, J. M., 2013, In : Cerebrovascular diseases. 35, Suppl 3, p. 562-562 1 p.

The third international stroke trial (IST-3) of intravenous rt-PA: effect of age and time on treatment effect among 3035 patients randomised

Sandercock, P. A. G., Wardlaw, J. M., Lindley, R., Cohen, G. & IST3 Collaborative Grp, Dec 2012, In : International Journal of Stroke. 7, p. 6-6 1 p.

The third international stroke trial (IST-3) of intravenous thrombolysis with rt-PA: baseline imaging features among 3035 patients randomised

Wardlaw, J., Sandercock, P., Lindley, R., Cohen, G., von Kummer, R., Farrall, A., Cala, L., von Heijne, A., Peeters, A., Morris, Z., Bradey, N., Adami, A., Potter, G., Perry, P., Sakka, E., IST3 Expert Image Reading Grp & IST3 Trialists, Dec 2012, In : International Journal of Stroke. 7, p. 61-62 2 p.

Improving the process of translational research

van der Worp, H. B. & Sandercock, P. A. G., 23 Nov 2012, In : British Medical Journal (BMJ). 345, 2 p., ARTN e7837.

Risk factors for intracranial hemorrhage in acute ischemic stroke patients treated with recombinant tissue plasminogen activator: a systematic review and meta-analysis of 55 studies

Whiteley, W. N., Slot, K. B., Fernandes, P., Sandercock, P. & Wardlaw, J., Nov 2012, In : Stroke. 43, 11, p. 2904-2909 6 p.

Thrombolysis in acute ischaemic stroke Reply

Sandercock, P., Wardlaw, J., Dennis, M., Murray, G. & Lindley, R., 22 Sep 2012, In : The Lancet. 380, 9847, p. 1054-1055 2 p.

Authors' reply

Sandercock, P., Wardlaw, J., Dennis, M., Murray, G. & Lindley, R., 1 Sep 2012, In : The Lancet. 380, 9847, p. 1054-1055 2 p.

The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial

Sandercock, P., Wardlaw, J. M., Lindley, R. I., Dennis, M., Cohen, G., Murray, G., Innes, K., Venables, G., Czlonkowska, A., Kobayashi, A., Ricci, S., Murray, V., Berge, E., Slot, K. B., Hankey, G. J., Correia, M., Peeters, A., Matz, K., Lyrer, P., Gubitz, G. & 5 others, Phillips, S. J., Arauz, A., IST-3 collaborative group, Al-Shahi Salman, R. & Lewis, S., Jun 2012, In : The Lancet. 379, 9834, p. 2352-2363 12 p.

Update on the 3rd international stroke trial; effects of thrombolysis among 3035 stroke patients within 6 h of onset

Sandercock, P., Jun 2012, In : Journal of Thrombosis and Haemostasis. 10, 6, p. E25-E25 1 p.

Negative results: why do they need to be published?

Sandercock, P., Jan 2012, In : International Journal of Stroke. 7, 1, p. 32-33 2 p.

CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury--a nested randomised, placebo-controlled trial

Perel, P., Salman, R. A-S., Kawahara, T., Morris, Z., Prieto-Merino, D., Roberts, I., Sandercock, P., Shakur, H. & Wardlaw, J., 2012, In : Health Technology Assessment. 16, 13, p. iii-xii, 1-54

Does intermittent pneumatic compression reduce the risk of post stroke deep vein thrombosis? The CLOTS 3 trial: study protocol for a randomized controlled trial

Dennis, M., Sandercock, P., Reid, J., Graham, C., Forbes, J., Murray, G. & CLOTS Trials Collaboration, 2012, In : Trials. 13, p. 26

Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis

Wardlaw, J. M., Murray, V., Berge, E., del Zoppo, G., Sandercock, P., Lindley, R. L. & Cohen, G., 2012, In : The Lancet. 379, 9834, p. 2364-72 9 p.

Risk factors for intracranial haemorrhage in acute stroke patients treated with rtPA

Whiteley, W., Slot, K. B., Fernandes, P., Sandercock, P. & Wardlaw, J., 2012, In : Stroke. 43, 11

Statistical analysis plan for the third International Stroke Trial (IST-3); part of a 'thread' of reports of the trial

Sandercock, P., Lindley, R., Wardlaw, J., Whiteley, W., Murray, G. & ST-3 collaborative group, 2012, In : International Journal of Stroke. 7, 3, p. 186-7 2 p.

The International Stroke Trial database

Sandercock, P. A., Niewada, M., Członkowska, A. & the International Stroke Trial Collaborative Group, 2012, In : Trials. 13, 1, p. 24

The Third International Stroke Trial (IST-3) of Thrombolysis. Main Results & Implications for Clinical Practice

Sandercock, P. & IST-3 Collaborative Grp, 2012, In : Cerebrovascular diseases. 34, p. 6-7 2 p.

The Use of Blood Biomarkers to Predict Poor Outcome After Acute Transient Ischemic Attack or Ischemic Stroke

Whiteley, W., Wardlaw, J., Dennis, M., Lowe, G., Rumley, A., Sattar, N., Welsh, P., Green, A., Andrews, M. & Sandercock, P., 2012, In : Stroke. 43, p. 86-91 6 p.

Hoover's sign for the diagnosis of functional weakness: A prospective unblinded cohort study in patients with suspected stroke

McWhirter, L., Stone, J., Sandercock, P. & Whiteley, W., Dec 2011, In : Journal of Psychosomatic Research. 71, 6, p. 384-386 3 p.

The timing, extent, progression and regression of deep vein thrombosis in immobile stroke patients: observational data from the CLOTS multicenter randomized trials

Dennis, M., Mordi, N., Graham, C., Sandercock, P. & on behalf of the CLOTS trials collaboration, Nov 2011, In : Journal of Thrombosis and Haemostasis. 9, 11, p. 2193-2200 8 p.

Can clinical features distinguish between immobile patients with stroke at high and low risk of deep vein thrombosis? Statistical modelling based on the CLOTS trials cohorts

Dennis, M., Sandercock, P., Reid, J., Graham, C., Murray, G., Venables, G., Rudd, A., Bowler, G. & CLOTS Trials Collaboration, Oct 2011, In : Journal of Neurology Neurosurgery & Psychiatry. 82, 10, p. 1067-1073 7 p.

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial

Baigent, C., Landray, M. J., Reith, C., Emberson, J., Wheeler, D. C., Tomson, C., Wanner, C., Krane, V., Cass, A., Craig, J., Neal, B., Jiang, L., Hooi, L. S., Levin, A., Agodoa, L., Gaziano, M., Kasiske, B., Walker, R., Massy, Z. A., Feldt-Rasmussen, B. & 31 others, Krairittichai, U., Ophascharoensuk, V., Fellström, B., Holdaas, H., Tesar, V., Wiecek, A., Grobbee, D., de Zeeuw, D., Grönhagen-Riska, C., Dasgupta, T., Lewis, D., Herrington, W., Mafham, M., Majoni, W., Wallendszus, K., Grimm, R., Pedersen, T., Tobert, J., Armitage, J., Baxter, A., Bray, C., Chen, Y., Chen, Z., Hill, M., Knott, C., Parish, S., Simpson, D., Sleight, P., Young, A., SHARP Investigators & Sandercock, P., Jun 2011, In : The Lancet. 377, 9784, p. 2181-2192 12 p.

Planning trials in older patients with stroke: data from the International Stroke Trial

Niewada, M., Sandercock, P. A. G., Lindley, R. I. & Czlonkowska, A., May 2011, In : Age and Ageing. 40, 3, p. 395-398 4 p.

Fatigue after Stroke: Baseline Predictors and Influence on Survival. Analysis of Data from UK Patients Recruited in the International Stroke Trial

Mead, G. E., Graham, C., Dorman, P., Bruins, S. K., Lewis, S. C., Dennis, M. S. & Sandercock, P. A. G., Mar 2011, In : PLoS ONE. 6, 3, e16988.

Investigator led trials: challenges and opportunities

Sandercock, P., 1 Jan 2011, In : Trials. 12, Suppl 1, p. A94

Association of Circulating Inflammatory Markers With Recurrent Vascular Events After Stroke: A Prospective Cohort Study

Whiteley, W., Jackson, C., Lewis, S., Lowe, G., Rumley, A., Sandercock, P., Wardlaw, J., Dennis, M. & Sudlow, C., Jan 2011, In : Stroke. 42, 1, p. 10-16 7 p.

Blood biomarkers for the diagnosis of acute cerebrovascular diseases: a prospective cohort study

Whiteley, W., Wardlaw, J., Dennis, M., Lowe, G., Rumley, A., Sattar, N., Welsh, P., Green, A., Andrews, M., Graham, C. & Sandercock, P., 2011, In : Cerebrovascular diseases (Basel, Switzerland). 32, 2, p. 141-7 7 p.

Brain imaging, the legal process and neurofantasy: can it be cured (by applying the principles of evidence-based medicine)?

Sandercock, P. & Wardlaw, J., 2011, In : SCRIPTed: A Journal of Law, Technology and Society. 8, p. 204-211

Clinical scores for the identification of stroke and transient ischaemic attack in the emergency department: a cross-sectional study

Whiteley, W. N., Wardlaw, J. M., Dennis, M. S. & Sandercock, P. A. G., 2011, In : Journal of Neurology, Neurosurgery & Psychiatry. 82, 9, p. 1006-10 5 p.

Comment on "Evidence-based guideline: the role of diffusion and perfusion MRI for the diagnosis of acute ischemic stroke: report of the Therapeutics and Technology Subcommittee of the American Academy of Neurology"

Brazzelli, M. G., Sandercock, P. & Wardlaw, J., 2011, In : Neurology. 76, 23, p. 2036-7; author reply 2038

Corticosteroids for acute ischaemic stroke

Sandercock, P. A. & Soane, T., 2011, In : Cochrane Database of Systematic Reviews. 9, p. CD000064

Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20,536 high-risk individuals: a randomised controlled trial

Bulbulia, R., Bowman, L., Wallendszus, K., Parish, S., Armitage, J., Peto, R., Collins, R., Heart Protection Study Collaborative Group & Sandercock, P., 2011, In : The Lancet. 378, 9808, p. 2013-20 8 p.

Neuroscience in fashion: An encounter at Inspace 14th April 2011, Edinburgh

Haley, J., Wardlaw, J., Schafer, B. & Sandercock, P., 2011, In : Advances in Clinical Neuroscience & Rehabilitation (ACNR). p. 44-45

The Brain, the Science and the Media: The Legal, Corporate, Social and Security Implications of Neuroimaging and the Impact of Media Coverage

O'Connell, G., Wilde, J. D., Haley, J., Shuler, K., Schafer, B., Sandercock, P. & Wardlaw, J. M., 2011, In : EMBO Reports. 12, p. 630-36 7 p.

The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial

Roberts, I., Shakur, H., Afolabi, A., Brohi, K., Coats, T., Dewan, Y., Gando, S., Guyatt, G., Hunt, B. J., Morales, C., Perel, P., Prieto-Merino, D., Woolley, T., CRASH-2 collaborators & Sandercock, P., 2011, In : The Lancet. 377, 9771, p. 1096-101, 1101.e1-2

Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited

Sandercock, P., Lindley, R., Wardlaw, J., Dennis, M., Innes, K., Cohen, G., Whiteley, W., Perry, D., Soosay, V., Buchanan, D., Venables, G., Czlonkowska, A., Kobayashi, A., Berge, E., Slot, K. B., Murray, V., Peeters, A., Hankey, G. J., Matz, K., Brainin, M. & 11 others, Ricci, S., Cantisani, T. A., Gubitz, G., Phillips, S. J., Arauz, A., Correia, M., Lyrer, P., Kane, I., Lundstrom, E., Lewis, S. & Ist-3 Collaborative Group, O. B. O. T., 2011, In : Trials. 12, 1, p. 252

“Can It Read My Mind?” – What Do the Public and Experts Think of the Current (Mis)Uses of Neuroimaging?

Wardlaw, J. M., O'connell, G., Shuler, K., Dewilde, J., Haley, J., Escobar, O., Murray, S., Rae, R., Jarvie, D., Sandercock, P. & Schafer, B., 2011, In : PLoS ONE. 6, 10, p. e25829

Factors affecting the apparent efficacy and safety of tissue plasminogen activator in thrombotic occlusion models of stroke: systematic review and meta-analysis

Sena, E. S., Briscoe, C. L., Howells, D. W., Donnan, G. A., Sandercock, P. A. G. & Macleod, M. R., Dec 2010, In : Journal of Cerebral Blood Flow and Metabolism. 30, 12, p. 1905-13 9 p.

What are You Thinking? Who Has the Right to Know? Brain Imaging and its Impact on Society

Wardlaw, J., Wilde, J. D., Sandercock, P., Haley, J., Schafer, B., Rae, R. & Jarvie, D., Dec 2010, Scottish Universities Insight Institute. 39 p.

Thigh-Length Versus Below-Knee Stockings for Deep Venous Thrombosis Prophylaxis After Stroke: A Randomized Trial

Dennis, M., Cranswick, G., Deary, A., Fraser, A., Graham, C., Grant, S., Gunkel, A., Hunter, J., MacRae, A., Perry, D., Soosay, V., Williams, C., Williamson, A., Young, A., Sandercock, P., Reid, J., Murray, G., Venables, G., Rudd, A., Bowler, G. & 10 others, Celani, M. G., Ricci, S., Lindley, R., Hautvast, M., Paterson, M., Ting, T., Baigent, C., Bamford, J., Slattery, J. & CLOTS Trial Collaborat, 2 Nov 2010, In : Annals of Internal Medicine. 153, 9, p. 553-562 10 p.

BLOOD MARKERS AND POOR OUTCOME AFTER ACUTE CEREBROVASCULAR DISEASE: A PROSPECTIVE COHORT STUDY

Whiteley, W., Rumley, A., Sattar, N., Wardlaw, J. M., Lowe, G. D. O., Welsh, P., Green, A., Sandercock, P. A. G. & Dennis, M. S., Nov 2010, In : Journal of Neurology, Neurosurgery & Psychiatry. 81, 11, p. E70-E70 1 p.

BLOOD MARKERS AND THE DIAGNOSIS OF STROKE OR TRANSIENT ISCHAEMIC ATTACK IN THE EMERGENCY DEPARTMENT: A PROSPECTIVE COHORT STUDY

Whiteley, W., Lowe, G. D., Rumley, N., Wardlaw, J. M., Green, V., Welsh, P., Dennis, M. S. & Sandercock, P. A. G., Nov 2010, In : Journal of Neurology, Neurosurgery & Psychiatry. 81, 11, p. E28-E29 10 p.

'Where are we now with intravenous thrombolysis for acute ischaemic stroke'?

Sandercock, P., Wardlaw, J. & Lindley, R., Oct 2010, In : International Journal of Stroke. 5, 5, p. 381-382 2 p.

How many patients might receive thrombolytic therapy in the light of the ECASS-3 and IST-3 data?

Bembenek, J., Kobayashi, A., Sandercock, P. & Czlonkowska, A., Oct 2010, In : International Journal of Stroke. 5, 5, p. 430-431 3 p.

Uncertainties Page How beneficial is surgery for cervical radiculopathy and myelopathy?

Fouyas, I. P., Sandercock, P. A. G., Statham, P. F. X. & Nikolaidis, I., 13 Jul 2010, In : British Medical Journal (BMJ). 341, p. - 5 p., c3108.

Quality Improvement Report A telephone hotline for transient ischaemic attack and stroke: prospective audit of a model to improve rapid access to specialist stroke care

Kerr, E., Arulraj, N., Scott, M., McDowall, M., van Dijke, M., Keir, S., Sandercock, P. & Dennis, M., 3 Jul 2010, In : British Medical Journal (BMJ). 341, p. - 8 p., c3265.

Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial

Shakur, H., Roberts, I., Bautista, R., Caballero, J., Coats, T., Dewan, Y., El-Sayed, H., Gogichaishvili, T., Gupta, S., Herrera, J., Hunt, B., Iribhogbe, P., Izurieta, M., Khamis, H., Komolafe, E., Marrero, M-A., Mejia-Mantilla, J., Miranda, J., Morales, C., Olaomi, O. & 31 others, Dashi, F., Perel, P., Peto, R., Ramana, P. V., Ravi, R. R., Yutthalcasemsunt, S., Dakubo, J., Gogichaishvili, T., Golden, N., Izurieta, M., Khamis, H., Komolafe, E., Loria-Castellanos, J., Mejia-Mantilla, J., Miranda, J., Munoz, A., Mutiso, V., Olcwen, P., Ortiz, Z., Pascual, M., Ravi, R., Roslani, A., Trenkler, S., Volpi, A., Yutthakasemsunt, S., Roberts, I., Shakur, H., Perel, P., Bametson, L., Sandercock, P. & Crash 2 Trial Collaborators, Jul 2010, In : The Lancet. 376, 9734, p. 23-32 10 p.

MRI versus CT for Detection of Acute Vascular Lesions in Patients Presenting with Stroke Symptoms

Brazzelli, M., Sandercock, P. A. G., Celani, M., Righetti, E., Chappell, F. M., Arestis, N., Wardlaw, J. M. & Deeks, J. J., May 2010, In : Stroke. 41, 5, p. e427-e428 2 p.

A systematic review of clinical trials of pharmacological interventions for acute ischaemic stroke (1955-2008) that were completed, but not published in full

Gibson, L. M., Brazzelli, M., Thomas, B. M. & Sandercock, P. A. G., 22 Apr 2010, In : Trials. 11, p. - 12 p., 43.

Age-Based Eligibility for and Treatment With rt-PA: A Population-based Estimate

Kleindorfer, D., Sandercock, P., Khoury, J., Alwell, K., Moomaw, C. J., Adeoye, O., Khatri, P., Woo, D., Flaherty, M. L., Ferioll, S. & Kissela, B. M., Apr 2010, In : Stroke. 41, 4, p. E202-E202 1 p.

Aspirin for Prevention of Cardiovascular Events in a General Population Screened for a Low Ankle Brachial Index: A Randomized Controlled Trial

Fowkes, F., Price, J., Stewart, M., Butcher, I., Leng, G. C., Pell, A. C. H., Sandercock, P. A. G., Fox, K. A. A., Lowe, G. D. O. & Murray, G. D., Mar 2010, In : JAMA: the Journal of the American Medical Association. 303, 9, p. 841-848 8 p.

The molecular basis of thrombolysis and its clinical application in stroke

Murray, V., Norrving, B., Sandercock, P. A. G., Terent, A., Wardlaw, J. M. & Wester, P., Feb 2010, In : Journal of Internal Medicine. 267, 2, p. 191-208 18 p.

'Yes' or 'No' to Routine Statins After Subarachnoid Hemorrhage to Prevent Delayed Cerebral Ischaemia, Vasospasm, and Death? A Cautionary Tale of 2 Meta-Analyses

Sandercock, P., Jan 2010, In : Stroke. 41, 1, p. E1-E2 2 p.

Does acetyl salicylic acid (ASA) have a role in the prevention of venous thromboembolism?

Lowe, G. & Sandercock, P., Jan 2010, In : British journal of haematology. 148, 2, p. 339-340 2 p.

Physical methods for preventing deep vein thrombosis in stroke

Naccarato, M., Grandi, F. C., Dennis, M. & Sandercock, P. A. G., 2010, In : Cochrane Database of Systematic Reviews. 8, p. - 26 p., CD001922.

Physical methods for preventing deep vein thrombosis in stroke

Naccarato, M., Chiodo Grandi, F., Dennis, M. & Sandercock, P. A., 2010, In : Cochrane Database of Systematic Reviews. 8, p. CD001922

Surgery for cervical radiculopathy or myelopathy

Nikolaidis, I., Fouyas, I. P., Sandercock, P. A. G. & Statham, P. F., 2010, In : Cochrane Database of Systematic Reviews. 1, p. - 52 p., CD001466.

Uncertainties Page Should more patients with acute ischaemic stroke receive thrombolytic treatment?

Wardlaw, J. M., Sandercock, P. A. G. & Murray, V., 11 Nov 2009, In : British Medical Journal (BMJ). 339, p. - 5 p., b4584.

Endovascular treatment with angioplasty or stenting versus endarterectomy in patients with carotid artery stenosis in the Carotid And Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial: long-term follow-up of a randomised trial

Ederle, J., Bonati, L. H., Dobson, J., Featherstone, R. L., Gaines, P. A., Beard, J. D., Venables, G. S., Markus, H. S., Clifton, A., Sandercock, P., Brown, M. M., CAVATAS Investigators & Sellar, R., Oct 2009, In : Lancet Neurology. 8, 10, p. 898-907 10 p.

Long-term risk of carotid restenosis in patients randomly assigned to endovascular treatment or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial

Bonati, L. H., Ederle, J., McCabe, D. J. H., Dobson, J., Featherstone, R. L., Gaines, P. A., Beard, J. D., Venables, G. S., Markus, H. S., Clifton, A., Sandercock, P., Brown, M. M., CAVATAS Investigators & Sellar, R., Oct 2009, In : Lancet Neurology. 8, 10, p. 908-917 10 p.

Inflammatory Markers and Poor Outcome after Stroke: A Prospective Cohort Study and Systematic Review of Interleukin-6

Whiteley, W., Jackson, C., Lewis, S., Lowe, G., Rumley, A., Sandercock, P., Wardlaw, J., Dennis, M. & Sudlow, C., Sep 2009, In : PLoS Medicine. 6, 9, e1000145.

WHAT HAVE WE LEARNED FROM STROKE TRIALS?

Sandercock, P., Aug 2009, In : Basic and Clinical Pharmacology and Toxicology. 105, p. 14-14 1 p.

Anticoagulants for Acute Ischemic Stroke

Sandercock, P., Counsell, C. & Kamal, A. K., Jul 2009, In : Stroke. 40, 7, p. E483-E484 2 p.

Effectiveness of thigh-length graduated compression stockings to reduce the risk of deep vein thrombosis after stroke (CLOTS trial 1): a multicentre, randomised controlled trial

Dennis, M., Cranswick, G., Deary, A., Fraser, A., Graham, C., Grant, S., Gunkel, A., Hunter, J., MacRae, A., Perry, D., Soosay, V., Williams, C., Williamson, A., Young, A., Sandercock, P. A. G., Reid, J., Murray, G., Venables, G., Rudd, A., Bowler, G. & 14 others, Lewis, S., Rudd, A., Celani, M. G., Ricci, S., Lindley, R., Hautvast, M., Paterson, M., Reid, J., Ting, T., Baigent, C., Bamford, J., Slattery, J., CLOTS Trials Collaboration & Wardlaw, J., Jun 2009, In : The Lancet. 373, 9679, p. 1958-1965 8 p.

Blood markers for the prognosis of ischemic stroke: a systematic review

Whiteley, W., Chong, W. L., Sengupta, A. & Sandercock, P., May 2009, In : Stroke. 40, 5, p. e380-9 10 p.

Causes of Death by Level of Dependency at 6 Months After Ischemic Stroke in 3 Large Cohorts

Slot, K. B., Berge, E., Sandercock, P., Lewis, S. C., Dorman, P., Dennis, M. & Oxfordshire Community Stroke Proje, Int Stroke Trial UK, May 2009, In : Stroke. 40, 5, p. 1585-1589 5 p.

No evidence of bias in the process of publication of diagnostic accuracy studies in stroke submitted as abstracts

Brazzelli, M., Lewis, S. C., Deeks, J. J. & Sandercock, P. A. G., Apr 2009, In : Journal of clinical epidemiology. 62, 4, p. 425-30 6 p.

THE DIAGNOSIS OF SUSPECTED STROKE IN THE EMERGENCY DEPARTMENT

Whiteley, W., Thomas, R. & Sandercock, P. A. G., Apr 2009, In : Journal of Neurology, Neurosurgery & Psychiatry. 80, 4, p. 466-466 1 p.

Intensive versus Conventional Glucose Control in Critically Ill Patients

Finfer, S., Blair, D., Bellomo, R., McArthur, C., Mitchell, I., Myburgh, J., Norton, R., Potter, J., Chittock, D., Dhingra, V., Foster, D., Cook, D., Dodek, P., Hebert, P., Henderson, W., Heyland, D., McDonald, E., Ronco, J., Schweitzer, L., Peto, R. & 31 others, Sandercock, P., Sprung, C., Young, J. D., Su, S., Heritier, S., Li, Q., Bompoint, S., Billot, L., Crampton, L., Darcy, F., Jayne, K., Kumarasinghe, V., Little, L., McEvoy, S., MacMahon, S., Pandey, S., Ryan, S., Shukla, R., Vijayan, B., Atherton, S., Bell, J., Hadfield, L., Hourigan, C., McArthur, C., Newby, L., Simmonds, C., Buhr, H., Eccleston, M., Smith, R., French, C. & Study Coordinating Ctr, NICE Australia-New Zealand, NICE-SUGAR Study Investigators, Australia-New Zealand Site, Study Stat Ctr, Inde-pendent Data Safety, SUGAR North Amer Management Comm, 26 Mar 2009, In : New England Journal of Medicine. 360, 13, p. 1283-1297 15 p.

Oxfordshire Community Stroke Project Clinical Stroke Syndrome and Appearances of Tissue and Vascular Lesions on Pretreatment CT in Hyperacute Ischemic Stroke Among the First 510 Patients in the Third International Stroke Trial (IST-3)

Kobayashi, A., Wardlaw, J. M., Lindley, R. I., Lewis, S., Sandercock, P. A. G., Czlonkowska, A. & IST-3 Collaborative Grp, Mar 2009, In : Stroke. 40, 3, p. 743-748 6 p.

Anticoagulants for preventing recurrence following presumed non-cardioembolic ischaemic stroke or transient ischaemic attack

Sandercock, P. A. G., Gibson, L. M. & Liu, M., 2009, In : Cochrane Database of Systematic Reviews. 2, p. - 50 p., CD000248.

Magnetic resonance imaging versus computed tomography for detection of acute vascular lesions in patients presenting with stroke symptoms

Brazzelli, M., Sandercock, P. A. G., Chappell, F. M., Celani, M. G., Righetti, E., Arestis, N., Wardlaw, J. M. & Deeks, J. J., 2009, In : Cochrane Database of Systematic Reviews. 4, p. - 56 p., CD007424.

The Third International Stroke Trial: Thrombolysis (IST-3) in Poland: are we recruiting the right patients?

Członkowska, A., Kobayashi, A., Sandercock, P., Lindley, R., Barańska-Gierszczak, M. & Lewis, S., 2009, In : Neurologia i neurochirurgia polska. 43, 3, p. 228-35 8 p.

A difficult case of postpartum collapse

Breen, D. P., Williams, A., Keston, P., Whittle, I. R. & Sandercock, P. A. G., Dec 2008, In : Practical neurology. 8, 6, p. 388-92 5 p.

Blood biomarkers in the diagnosis of ischemic stroke: a systematic review

Whiteley, W., Tseng, M-C. & Sandercock, P., Oct 2008, In : Stroke. 39, 10, p. 2902-9 8 p.

Low dose aspirin and cognitive function in middle aged to elderly adults: randomised controlled trial

Price, J. F., Stewart, M. C., Deary, I. J., Murray, G. D., Sandercock, P., Butcher, I., Fowkes, F. G. R. & AAA Trialists, 1 Sep 2008, In : British Medical Journal (BMJ). 337, n/a, 8 p., a1198.

The third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke

Sandercock, P., Lindley, R., Wardlaw, J., Dennis, M., Lewis, S., Venables, G., Kobayashi, A., Czlonkowska, A., Berge, E., Slot, K. B., Murray, V., Peeters, A., Hankey, G., Matz, K., Brainin, M., Ricci, S., Celani, M. G., Righetti, E., Cantisani, T., Gubitz, G. & 6 others, Phillips, S., Arauz, A., Prasad, K., Correia, M., Lyrer, P. & IST 3 Collaborative Grp, 17 Jun 2008, In : Trials. 9, p. - 17 p., 37.

Impact of functional status at six months on long term survival in patients with ischaemic stroke: prospective cohort studies

Slot, K. B., Berge, E., Dorman, P., Lewis, S., Dennis, M., Sandercock, P. & Lothiar Stroke Register, Oxfordshire Community Stroke Proje, Int Stroke Trial, 16 Feb 2008, In : British Medical Journal (BMJ). 336, 8 p., 376.

Anticoagulants for acute ischaemic stroke

Sandercock, P. A. G., Counsell, C. & Kamal, A. K., 2008, In : Cochrane Database of Systematic Reviews. 4, p. - 90 p., CD000024.

Antiplatelet therapy for acute ischaemic stroke

Sandercock, P. A. G., Counsell, C., Gubitz, G. J. & Tseng, M-C., 2008, In : Cochrane Database of Systematic Reviews. 3, p. - 74 p., CD000029.

Availability of CT and MR for assessing patients with acute stroke

Kane, I., Whiteley, W. N., Sandercock, P. A. G. & Wardlaw, J. M., 2008, In : Cerebrovascular diseases (Basel, Switzerland). 25, 4, p. 375-7 3 p.

EPITHET--where next?

Sandercock, P., Wardlaw, J., Dennis, M., Lindley, R., Hankey, G., Matz, K., Peeters, A., Phillips, S., Gubitz, G., Prasad, K., Ricci, S., Celani, M. G., Righetti, E., Cantisani, T., Arauz, A., Berge, E., Slot, K. B., Kobayashi, A., Czlonkowska, A., Correia, M. & 4 others, Murray, V., Lyrer, P., Venables, G. & IST-3 Collaborative Group, 2008, In : Lancet Neurology. 7, 7, p. 570-1; author reply 571-3

Low-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke

Sandercock, P. A. G., Counsell, C. & Tseng, M-C., 2008, In : Cochrane Database of Systematic Reviews. 3, p. - 49 p., CD000119.

Predicting outcome in hyper-acute stroke: validation of a prognostic model in the Third International Stroke Trial (IST3)

Lewis, S. C., Sandercock, P. A. G., Dennis, M. S. & SCOPE (Stroke Complications and Outcomes Prediction Engine) Collaborations, 2008, In : Journal of Neurology, Neurosurgery & Psychiatry. 79, 4, p. 397-400 4 p.

Prevention of venous thromboembolism after acute ischaemic stroke

Ricci, S., Celani, M. G., Righetti, E., Dennis, M. & Sandercock, P., 1 Sep 2007, In : The Lancet. 370, 9589, p. 735-736 2 p.

Systematic review and meta-analysis of the efficacy of tirilazad in experimental stroke

Sena, E., Wheble, P., Sandercock, P. & Macleod, M., Feb 2007, In : Stroke. 38, 2, p. 388-394 7 p.

Comparison of treatment effects between animal experiments and clinical trials: systematic review

Perel, P., Roberts, I., Sena, E., Wheble, P., Briscoe, C., Sandercock, P., Macleod, M., Mignini, L. E., Jayaram, P. & Khan, K. S., 27 Jan 2007, In : British Medical Journal (BMJ). 334, 7586, p. 197-197

Research governance impediments to clinical trials: a retrospective survey

Al-Shahi Salman, R., Brock, T. M., Dennis, M. S., Sandercock, P. A. G., White, P. M. & Warlow, C., 2007, In : Journal of the Royal Society of Medicine. 100, 2, p. 101-4 4 p.

The NeuroGrid stroke exemplar clinical trial protocol

Wardlaw, J. M., Bath, P., Sandercock, P., Perry, D., Palmer, J., Watson, G., Lloyd, S., Geddes, J. & Farrall, A., 2007, In : International Journal of Stroke. 2, 1, p. 63-9 7 p.

The challenges of developing a collaborative data and compute grid for neurosciences

Geddes, J., Mackay, C., Lloyd, S., Simpson, A., Power, D., Russell, D., Katzarova, M., Rossor, M., Fox, N., Fletcher, J., Hill, D., McLeish, K., Hajnal, J. V., Lawrie, S., Job, D., McIntosh, A., Wardlaw, J., Sandercock, P., Palmer, J., Perry, D. & 4 others, Procter, R., Ure, J., Bath, P. & Watson, G., 22 Dec 2006, Proceedings - 19th IEEE International Symposium on Computer-Based Medical Systems, CBMS 2006. Vol. 2006. p. 81-86 6 p. 1647550

Designing for e-Health: recurring scenarios in developing grid-based medical imaging systems

Geddes, J., Mackay, C., Lloyd, S., Simpson, A., Power, D., Russell, D., Jirotka, M., Katzarova, M., Rossor, M., Fox, N., Fletcher, J., Hill, D., McLeish, K., Chen, Y., Hajnal, J. V., Lawrie, S., Job, D., McIntosh, A., Wardlaw, J., Sandercock, P. & 11 others, Palmer, J., Perry, D., Procter, R., Ure, J., Hartswood, M., Slack, R., Voss, A., Ho, K., Bath, P., Clarke, W. & Watson, G., 2006, In : Stud Health Technol Inform. 120, p. 336-47 12 p.

Impact of stroke syndrome and stroke severity on the process of consent in the third international stroke trial

Kane, I., Lindley, R., Lewis, S. & Sandercock, P., 2006, In : Cerebrovascular diseases. 21, p. 348-352

Previous use of aspirin and baseline stroke severity: an analysis of 17850 patients in the international stroke trial

Ricci, S., Lewis, S. & Sandercock, P., 2006, In : Stroke. 37, p. 1737-1740

Third international stroke trial

Whiteley, W., Lindley, R., Wardlaw, J., Sandercock, P. & IST-3 Collaborative Group, 2006, In : International Journal of Stroke. 1, 3, p. 172-6 5 p.

Uncertainties about thrombolysis for stroke should be addressed with large-scale randomized trials

Whiteley, W., Sandercock, P., Wardlaw, J. & Lindley, R., 2006, In : Stroke; a journal of cerebral circulation. 37, 11, p. 2662; author reply 2664-5

Trauma care research and the war on uncertainty

Roberts, I., Shakur, H., Edwards, P., Yates, D. & Sandercock, P., 12 Nov 2005, In : British Medical Journal (BMJ). 331, 7525, p. 1094-6 3 p.

International subarachnoid aneurysm trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised comparison of effects on survival, dependency, seizures, rebleeding, subgroups, and aneurysm occlusion

Molyneux, A. J., Kerr, R. S. C., Yu, L. M., Clarke, M., Sneade, M., Yarnold, J. A., Sandercock, P. & ISAT Collaborative Grp, 3 Sep 2005, In : The Lancet. 366, 9488, p. 809-817 9 p.

An unusual vascular cause of Horner's syndrome

Whiteley, W. N. & Sandercock, P. A. G., 2005, In : Cerebrovascular diseases (Basel, Switzerland). 19, 5, p. 351-2 2 p.

Magnesium for acute stroke (Intravenous Magnesium Efficacy in Stroke trial): Randomised controlled trial

Lees, K. R., Muir, K. W., Ford, I., Reid, L., Mendelow, A. D., Sandercock, P. A. G., Bath, P. M. W., Chen, C., Davis, S. M., Phillips, S. J., Saver, J., Vanhooren, G., Forbes, C., Murray, G., Bone, I., Norrie, J., Kean, S., Robertson, M., Murray, H., McIlvenna, Y. & 9 others, Gardner, A., Bradford, A., Fenton, J., Sakhri, A., Rodger, M., Sanmuganathan, P., Milia, P., Chong, V. & Teasdale, E., 7 Feb 2004, In : The Lancet. 363, 9407, p. 439-445 7 p.

Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study)

Rothwell, P. M., Coull, A. J., Giles, M. F., Howard, S. C., Silver, L. E., Bull, L. M., Gutnikov, S. A., Edwards, P., Mant, D., Sackley, C. M., Farmer, A., Sandercock, P. A. G., Dennis, M. S., Warlow, C. P., Bamford, J. M., Anslow, P. & Oxford Vascular Study, 2004, In : The Lancet. 363, 9425, p. 1925-33 9 p.

Cost-effectiveness of thrombolysis with recombinant tissue plasminogen activator for acute ischemic stroke assessed by a model based on UK NHS costs

Sandercock, P., Berge, E., Dennis, M., Forbes, J., Hand, P., Kwan, J., Lewis, S., Lindley, R., Neilson, A. & Wardlaw, J., 2004, In : Stroke. 35, 6, p. 1490-7 8 p.

Effects of introducing an integrated care pathway in an acute stroke unit

Kwan, J., Hand, P., Dennis, M. & Sandercock, P., 2004, In : Age and Ageing. 33, 4, p. 362-7 6 p.

Frequency and risk factors for spontaneous hemorrhagic transformation of cerebral infarction

Lindley, R., Wardlaw, J., Sandercock, P., Rimdusid, P. & Lewis, S., 2004, In : Journal of Stroke and Cerebrovascular Diseases. 13, p. 235-246

Immediate computed tomography scanning of acute stroke is cost-effective and improves quality of life

Wardlaw, J. M., Seymour, J., Cairns, J., Keir, S., Lewis, S. & Sandercock, P., 2004, In : Stroke; a journal of cerebral circulation. 35, 11, p. 2477-83 7 p.

What is the best imaging strategy for acute stroke?

Wardlaw, J. M., Keir, S. L., Seymour, J., Lewis, S., Sandercock, P. A. G., Dennis, M. S. & Cairns, J., 2004, In : Health Technology Assessment. 8, 1, p. iii, ix-x, 1-180

Very early risk of stroke after a first transient ischemic attack

Lovett, J. K., Dennis, M. S., Sandercock, P. A. G., Bamford, J., Warlow, C. P. & Rothwell, P. M., Aug 2003, In : Stroke; a journal of cerebral circulation. 34, 8, p. e138-40

Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia?

Wardlaw, J. M., Sandercock, P. A. G., Dennis, M. S. & Starr, J., Mar 2003, In : Stroke; a journal of cerebral circulation. 34, 3, p. 806-12 7 p.

Internet resources for neurologists

Al-Shahi, R. & Sandercock, P. A. G., 2003, In : Journal of Neurology, Neurosurgery & Psychiatry. 74, 6, p. 699-703 5 p.

Stroke

Warlow, C., Sudlow, C., Dennis, M., Wardlaw, J. & Sandercock, P., 2003, In : The Lancet. 362, 9391, p. 1211-24 14 p.

Visible infarction on computed tomography is an independent predictor of poor functional outcome after stroke, and not of haemorrhagic transformation

Wardlaw, J., West, T., Sandercock, P., Lewis, S. & Mielke, O., 2003, In : Journal of Neurology, Neurosurgery & Psychiatry. 74, p. 452-458

Antiplatelet therapy and atherosclerotic events. Commentary is inaccurate

Sudlow, C., Sandercock, P. & Warlow, C., 13 Apr 2002, In : British Medical Journal (BMJ). 324, 7342, p. 917

A systematic review of the effectiveness, cost-effectiveness and barriers to implementation of thrombolytic and neuroprotective therapy for acute ischaemic stroke in the NHS

Sandercock, P., Berge, E., Dennis, M., Forbes, J., Hand, P., Kwan, J., Lewis, S., Lindley, R., Neilson, A., Thomas, B. & Wardlaw, J., 2002, In : Health Technology Assessment. 6, 26, p. 1-112 112 p.

High early case fatality after ischaemic stroke in Poland: exploration of possible explanations in the international stroke trial

Czlonkowska, A., Niewada, M., El-Baroni, IS., Mendel, T., Ryglewitz, D., Sandercock, P. & Lewis, S., 2002, In : Journal of the Neurological Sciences. 202, p. 53-57

Physical methods for preventing deep vein thrombosis in stroke

Mazzone, C., Chiodo Grandi, F., Sandercock, P., Miccio, M. & Salvi, R., 2002, In : Cochrane Database of Systematic Reviews. CD001922.

Imaging appearance of the symptomatic perforating artery in patients with lacunar infarction: occlusion or other vascular pathology?

Wardlaw, J. M., Dennis, M. S., Warlow, C. P. & Sandercock, P. A., Aug 2001, In : Annals of Neurology. 50, 2, p. 208-15 8 p.

Venous thromboembolism after acute stroke

Sandercock, P. & Dennis, M., Jun 2001, In : Stroke; a journal of cerebral circulation. 32, 6, p. 1443-8 6 p.

Care for stroke patients

Dennis, M. & Sandercock, P., 13 Jan 2001, In : The Lancet. 357, 9250, p. 146; author reply 147

Risk of early death and recurrent stroke and effect of heparin in 3169 patients with acute ischemic stroke and atrial fibrillation in the international stroke trial

Saxena, R., Lewis, S., Berge, E., Sandercock, P. & Koudstaal, P. J., 2001, In : Stroke. 32, p. 2333-2337

Variations between countries in outcome after stroke in the international stroke trial

Weir, N. U., Sandercock, P., Lewis, S., Signorini, D. F. & Warlow, C., 2001, In : Stroke. 32, p. 1370-1377

Are the modified "simple questions" a valid and reliable measure of health related quality of life after stroke? United Kingdom Collaborators in the International Stroke Trial

Dorman, P., Dennis, M. & Sandercock, P., Oct 2000, In : Journal of Neurology, Neurosurgery & Psychiatry. 69, 4, p. 487-93 7 p.

Neuroprotection disappointment yet aGAIN

Wardlaw, J. M., Warlow, C. P., Sandercock, P. A., Dennis, M. S. & Lindley, R. I., 12 Aug 2000, In : The Lancet. 356, 9229, p. 597

Indications for early aspirin use in acute ischemic stroke: A combined analysis of 40 000 randomized patients from the Chinese acute stroke trial and the international stroke trial. On behalf of the CAST and IST collaborative groups

Chen, Z. M., Sandercock, P., Pan, H. C., Counsell, C., Collins, R., Liu, L. S., Xie, J. X., Warlow, C. & Peto, R., Jun 2000, In : Stroke; a journal of cerebral circulation. 31, 6, p. 1240-9 10 p.

Anticoagulants for acute ischaemic stroke.

Gubitz, G., Counsell, C., Sandercock, P. & Signorini, D., 2000, In : Cochrane Database of Systematic Reviews.

Families of trials: the answers to all our questions?

Dennis, M., Wardlaw, J., Sandercock, P., Signorini, D. & Warlow, C., 5 Nov 1999, In : Cerebrovascular diseases (Basel, Switzerland). 9, 6, p. 305-13 9 p.

Antiplatelet therapy in acute cerebral ischaemia

Sandercock, P., Warlow, C., Dennis, M. & Chen, Z. M., Oct 1999, In : Stroke; a journal of cerebral circulation. 30, 10, p. 2245-6 2 p.

How do scores on the EuroQol relate to scores on the SF-36 after stroke?

Dorman, P. J., Dennis, M. & Sandercock, P., Oct 1999, In : Stroke; a journal of cerebral circulation. 30, 10, p. 2146-51 6 p.

Recently occluded intracranial and extracranial carotid arteries. Relevance of the unstable atherosclerotic plaque

Lammie, G. A., Sandercock, P. A. & Dennis, M. S., Jul 1999, In : Stroke; a journal of cerebral circulation. 30, 7, p. 1319-25 7 p.

Can stroke physicians and neuroradiologists identify signs of early cerebral infarction on CT?

Wardlaw, J., Dorman, P., Lewis, S. & Sandercock, P., 1999, In : Journal of Neurology, Neurosurgery & Psychiatry. 67, 5, p. 651-653

Why do Italian stroke patients receive CT scans earlier than UK patients?

Wardlaw, J., Lewis, S., Sandercock, P., Ricci, S. & Spizzichino, L., 1999, In : Postgraduate Medical Journal. 75, 879, p. 18-21

Qualitative comparison of the reliability of health status assessments with the EuroQol and SF-36 questionnaires after stroke. United Kingdom Collaborators in the International Stroke Trial

Dorman, P., Slattery, J., Farrell, B., Dennis, M. & Sandercock, P., Jan 1998, In : Stroke; a journal of cerebral circulation. 29, 1, p. 63-8 6 p.

Epileptic seizures after a first stroke: the Oxfordshire Community Stroke Project

Burn, J., Dennis, M., Bamford, J., Sandercock, P., Wade, D. & Warlow, C., 13 Dec 1997, In : British Medical Journal (BMJ). 315, 7122, p. 1582-7 6 p.

Are proxy assessments of health status after stroke with the EuroQol questionnaire feasible, accurate, and unbiased?

Dorman, P. J., Waddell, F., Slattery, J., Dennis, M. & Sandercock, P., Oct 1997, In : Stroke; a journal of cerebral circulation. 28, 10, p. 1883-7 5 p.

Is the EuroQol a valid measure of health-related quality of life after stroke?

Dorman, P. J., Waddell, F., Slattery, J., Dennis, M. & Sandercock, P., Oct 1997, In : Stroke; a journal of cerebral circulation. 28, 10, p. 1876-82 7 p.

A randomised comparison of the EuroQol and Short Form-36 after stroke. United Kingdom collaborators in the International Stroke Trial

Dorman, P. J., Slattery, J., Farrell, B., Dennis, M. S. & Sandercock, P. A., 23 Aug 1997, In : British Medical Journal (BMJ). 315, 7106, p. 461

The International Stroke Trial (IST): A randomised trial of aspirin, subcutaneous heparin, both, or neither among 19 435 patients with acute ischaemic stroke

International Stroke Trial Collaborative Group, 31 May 1997, In : The Lancet. 349, 9065, p. 1569-1581 13 p.

Acute stroke treatment in UK hospitals: the Stroke Association survey of consultant opinion

Lindley, R. I., Amayo, E. O., Marshall, J., Sandercock, P. A., Dennis, M. & Warlow, C. P., 1 Nov 1995, In : Journal of the Royal College of Physicians of London. 29, 6, p. 479-84 6 p.

Hospital services for patients with acute stroke in the United Kingdom: the Stroke Association Survey of consultant opinion

Lindley, R. I., Amayo, E. O., Marshall, J., Sandercock, P. A., Dennis, M. & Warlow, C. P., Nov 1995, In : Age and Ageing. 24, 6, p. 525-32 8 p.

How should a patient presenting with unstable angina and a recent stroke be managed?

Davenport, R. J., Dennis, M. S., Sandercock, P. A., Warlow, C. P., Starkey, I. R., Ruckley, C. V., Porter, J. M., Jackson, G., Ohman, E. M. & Hornick, P., 3 Jun 1995, In : British Medical Journal (BMJ). 310, 6992, p. 1449-52 4 p.

Long-term risk of recurrent stroke after a first-ever stroke. The Oxfordshire Community Stroke Project

Burn, J., Dennis, M., Bamford, J., Sandercock, P., Wade, D. & Warlow, C., Feb 1994, In : Stroke; a journal of cerebral circulation. 25, 2, p. 333-7 5 p.

Interobserver reliability of a clinical classification of acute cerebral infarction

Lindley, R. I., Warlow, C. P., Wardlaw, J. M., Dennis, M. S., Slattery, J. & Sandercock, P. A., Dec 1993, In : Stroke; a journal of cerebral circulation. 24, 12, p. 1801-4 4 p.

Long-term survival after first-ever stroke: the Oxfordshire Community Stroke Project

Dennis, M. S., Burn, J. P., Sandercock, P. A., Bamford, J. M., Wade, D. T. & Warlow, C. P., Jun 1993, In : Stroke; a journal of cerebral circulation. 24, 6, p. 796-800 5 p.

Atrial fibrillation and stroke: prevalence in different types of stroke and influence on early and long term prognosis (Oxfordshire community stroke project)

Sandercock, P., Bamford, J., Dennis, M., Burn, J., Slattery, J., Jones, L., Boonyakarnkul, S. & Warlow, C., 12 Dec 1992, In : British Medical Journal (BMJ). 305, 6867, p. 1460-5 6 p.

Diurnal variation in incidence of stroke: Oxfordshire community stroke project

Wroe, S. J., Sandercock, P., Bamford, J., Dennis, M., Slattery, J. & Warlow, C., 18 Jan 1992, In : British Medical Journal (BMJ). 304, 6820, p. 155-7 3 p.

Classification and natural history of clinically identifiable subtypes of cerebral infarction

Bamford, J., Sandercock, P., Dennis, M., Burn, J. & Warlow, C., 22 Jun 1991, In : The Lancet. 337, 8756, p. 1521-6 6 p.

The frequency, causes and timing of death within 30 days of a first stroke: the Oxfordshire Community Stroke Project

Bamford, J., Dennis, M., Sandercock, P., Burn, J. & Warlow, C., Oct 1990, In : Journal of Neurology, Neurosurgery & Psychiatry. 53, 10, p. 824-9 6 p.

Computed tomography in patients with transient ischaemic attacks: when is a transient ischaemic attack not a transient ischaemic attack but a stroke?

Dennis, M., Bamford, J., Sandercock, P., Molyneux, A. & Warlow, C., Jul 1990, In : Journal of Neurology. 237, 4, p. 257-61 5 p.

Prognosis of transient ischemic attacks in the Oxfordshire Community Stroke Project

Dennis, M., Bamford, J., Sandercock, P. & Warlow, C., Jun 1990, In : Stroke; a journal of cerebral circulation. 21, 6, p. 848-53 6 p.

A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project--1981-86. 2. Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primary intracerebral and subarachnoid haemorrhage

Bamford, J., Sandercock, P., Dennis, M., Burn, J. & Warlow, C., Jan 1990, In : Journal of Neurology, Neurosurgery & Psychiatry. 53, 1, p. 16-22 7 p.

A comparison of risk factors and prognosis for transient ischemic attacks and minor ischemic strokes. The Oxfordshire Community Stroke Project

Dennis, M. S., Bamford, J. M., Sandercock, P. A. & Warlow, C. P., Nov 1989, In : Stroke; a journal of cerebral circulation. 20, 11, p. 1494-9 6 p.

Incidence of transient ischemic attacks in Oxfordshire, England

Dennis, M. S., Bamford, J. M., Sandercock, P. A. & Warlow, C. P., Mar 1989, In : Stroke; a journal of cerebral circulation. 20, 3, p. 333-9 7 p.

Lone bilateral blindness: a transient ischaemic attack

Dennis, M. S., Bamford, J. M., Sandercock, P. A. & Warlow, C. P., 28 Jan 1989, In : The Lancet. 1, 8631, p. 185-8 4 p.

A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project 1981-86. 1. Methodology, demography and incident cases of first-ever stroke

Bamford, J., Sandercock, P., Dennis, M., Warlow, C., Jones, L., McPherson, K., Vessey, M., Fowler, G., Molyneux, A. & Hughes, T., Nov 1988, In : Journal of Neurology, Neurosurgery & Psychiatry. 51, 11, p. 1373-80 8 p.

Projects

A multicentre randomised trial to establish the effect (S) of routine administration of fluoxetine in patients with a recent stroke: Start up phase

Dennis, M., Forbes, J., Lewis, S., MacLeod, M., Mead, G. & Sandercock, P.

UK-based charities

1/04/1231/03/15

A robust neurology teaching programme in the college of medicine

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/04/0731/01/08

An assessment of the cost effectiveness of magnetic resonance including diffusion-weighted brain imaging in patients with transient ischaemic attack and minor stroke

Wardlaw, J., DeWilde, J., Dennis, M. & Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/10/1031/03/12

An initial phase of a multicentre randomised trial of graduated compression stockings (GCS) to prevent post stroke deep vein

Dennis, M. & Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/05/0130/04/03

CLOTS - Clots in legs or TEDS after Stroke

Dennis, M. & Sandercock, P.

MRC

1/10/0328/02/10

CLOTS 3 trial

Dennis, M., Forbes, J. & Sandercock, P.

Other

1/04/1030/09/14

COCHRANE STROKE GROUP

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/07/0330/06/06

COCHRANE STROKE GROUP 2010

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/04/1031/03/15

CSO Primary Care Research Career Award: The symptoms clinic using GPs with a special interestto manage unsuccessful referrals to medically unexplained symptoms

Burton, C. & Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/01/0729/02/12

Can we improve the validity and reliability of CT scan interpretation in acute ischaemic stroke.

Wardlaw, J. & Sandercock, P.

UK-based charities

1/06/0031/12/02

Chief Scientist Office CZG/2/378 Start up phase for CLOTS3

Dennis, M., Lewis, S. & Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/11/0830/11/11

Clerical support for Cochrane Stroke Group

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/04/0430/06/06

Clinician Scientist Fellowship - Dr C Sudlow

Sudlow, C., Dennis, M. & Sandercock, P.

UK-based charities

1/10/0110/07/07

Cochrane Stroke Group 2006

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/10/0630/06/11

DORIS: Database of research ion stroke

Sandercock, P.

Other

1/08/0929/02/12

Development of Novel Device to Detect Epileptic Seizures - Dr Ruth Brotherstone

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/05/1331/12/19

Edinburgh Trials Methodology Hub

Sandercock, P., Sheikh, A., Lewis, S., MacLeod, M., Ralston, S., Sandercock, P., Sharpe, M. & Sheikh, A.

MRC

1/01/0931/08/15

Evaluation of Blood Biomarkers for more Accurate Diagnosis and Management of Acute Stroke

Whiteley, W., Sandercock, P. & Wardlaw, J.

UK central government bodies/local authorities, health and hospital authorities

1/12/0631/12/09

HOW CAN WE IDENTIFY PROMISING REHABILITATION TREATMENTS AT AN EARLY STAGE IN THE RESEARCH PROCESS?

Sandercock, P.

Other

1/12/1230/11/14

Hypothermia for Acute Ischaemic Stroke - A Pilot Study

MacLeod, M., Andrews, P., Marshall, I., Sandercock, P. & Wardlaw, J.

UK-based charities

1/02/0931/01/12

IN SUPPORT OF RESEARCH

Sandercock, P.

UK industry, commerce and public corporations

5/07/9530/06/00

IST3 (Supplement to R39189) - Third International Stroke Trial (Formerlly MRC G0400069)

Sandercock, P., Dennis, M. & Wardlaw, J.

Other, UK-based charities

1/04/1030/09/13

Imaging perfusion deficits and thrombolysis safety and efficacy in acute ischaemic stroke. The Third International Stroke Trial (IST-3)

Wardlaw, J. & Sandercock, P.

Other

1/09/0931/12/12

International Stroke Trial (BIOMED)

Sandercock, P.

EU government bodies

1/11/9231/12/96

Methodology for systematic reviews of animal experiments

Sandercock, P.

UK-based charities

1/05/0531/01/08

Neurogrid

Wardlaw, J., Lawrie, S., Procter, R. & Sandercock, P.

MRC, Other

1/04/0531/03/08

PROGRESS

Sandercock, P.

Non-EU other

1/10/9630/09/01

Practical methods for ordinal data meta-analysis in stroke

Lewis, S., Murray, G. & Sandercock, P.

MRC

1/06/1030/11/12

Practical, Streamlined and Optimal Use of Imaging in Acute Stroke

Wardlaw, J. & Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/12/0430/09/06

RESEARCH TRAINING FELLOWSHIP IN HEALTH SCIENCE RESEARCH DEVELOPING THE METHODS FOR COCHRANE SYSTEMATIC REVIEWS OF DIAGNOSTIC ACCURACY IN STOKE MEDICINE

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/02/0531/08/10

Randomised controlled trial of asprin

Price, J., Deary, I., Fowkes, G., Murray, G. & Sandercock, P.

UK-based charities

1/04/0031/05/07

Real-World Independent Testing of eASPECTS Software (RITeS)

Mair, G., MacLeod, M., Salman, R., Sandercock, P. & Wardlaw, J.

UK-based charities

28/02/1931/12/20

STROKE RESEARCH - JO KWAN

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/11/0131/01/02

SUPPORT FOR DR R AL-SHAHI

Sandercock, P.

UK-based charities

1/12/0128/02/02

Systematic Review: new drugs for acute ischaemic stroke

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/02/0031/07/01

THIRD INTERNATIONAL STROKE TRIAL

Warlow, C., Dennis, M., Sandercock, P. & Wardlaw, J.

UK-based charities

1/12/0230/11/05

Targeted treatment for acute stroke: development of prognostic models & decision support tools

Whiteley, W. & Sandercock, P.

MRC

1/09/1028/02/16

The International Stroke Trial

Sandercock, P.

UK-based charities

1/05/9330/04/96

The Scottish Collaboration of Trialists (SCoT)

Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/11/0530/09/11

The stroke collaborative review group of the Cochrane collaboration

Warlow, C. & Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/01/9430/06/03

The treatment and prevention of stroke

Sandercock, P.

MRC

1/03/9731/03/99

Thrombolysis for Acute Ischaemic Stroke

Sandercock, P. & Wardlaw, J.

UK-based charities

1/07/9931/12/02

Trial development grant

Sandercock, P.

UK industry, commerce and public corporations

1/08/9631/12/03

What is the best imaging strategy for acute stroke?

Wardlaw, J., Dennis, M. & Sandercock, P.

UK central government bodies/local authorities, health and hospital authorities

1/02/9931/01/01

Press clippings

Prof Peter Sandercock comments on report on how to treat stroke patients

Peter Sandercock

16/06/15

1 item of Media coverage

Prof Peter Sandercock finds benefits in taking aspirin may be outweighed by risks

Peter Sandercock

21/12/13

14 items of Media coverage

Prof Peter Sandercock finds clot-busting drug limits brain damage in stroke patients

Peter Sandercock

5/08/14

3 items of Media coverage

Professor Peter Sandercock finds clot-busting drug can benefit stroke patients

Peter Sandercock

23/05/12

30 items of Media coverage

Professor Peter Sandercock finds new clot-busting stroke treatment improves patient outlook

Peter Sandercock

21/06/13

21 items of Media coverage

Professor Peter Sandercock finds quick treatment with clot-busting drug limits brain damage in stroke patients

Peter Sandercock

15/02/14

1 item of Media coverage

Profs Joanna Wardlaw and Peter Sandercock seeks to limit brain damage in stroke patients with clot-busting drug

Joanna Wardlaw & Peter Sandercock

10/04/15

10 items of Media coverage