Edinburgh Research Explorer

Dr Rachel Challis

(Former employee or visitor)

  1. 2018
  2. CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions

    Zimmermann, M. , Murina, O. , Reijns, M. , Agathanggelou, A. , Challis, R. , Tarnauskaite, Z. , Muir, M. , Fluteau, A. , Aregger, M. , McEwan, A. , Yuan, W. , Clarke, M. , Lambros, M. , Paneesha, S. , Moss, P. , Chandrashekhar, M. , Angers, S. , Moffat, J. , Brunton, V. , Hart, T. & 4 others de Bono, J., Stankovic, T., Jackson, A. & Durocher, D. 4 Jul 2018 In : Nature.

    Research output: Contribution to journalArticle

  3. 2017
  4. Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism.

    Reynolds, J. , Bicknell, L. , Carroll, P. , Higgs, M. , Shaheen, R. , Murray, J. , Papadopoulos, D. K. , Leitch, A. , Murina, O. , Tarnauskaite, Z. , Wessel, S. R. , Zlatanou, A. , Vernet, A. , Von Kriegsheim, A. , Mottram, R. M. , Logan, C. , Bye, H. , Li, Y. , Brean, A. , Maddirevula, S. & 41 others Challis, R., Skouloudaki, K., Almoisheer, A., Alsaif, H. S., Amar, A., Prescott, N. J., Bober, M., Duker, A., Faqeih, E., Seidahmed, M. Z., Tala, S. A., Alswaid, A., Ahmed, S., Al-Aama, J. Y., Altmuller, J., Al Balwi, M., Brady, A., Chessa, L., Cox, H., Fischetto, R., Heller, R., Henderson, B. D., Hobson, E., Nurnberg, P., Percin, F., Peron, A., Spaccini, L., Quigley, A., Thakur, S., Wise, C. A., Yoon, G., Alnemer, M., Yigit, G., Taylor, A. M. R., Reijns, M., Simpson, M. A., Cortez, D., Alkuraya, F. S., Mathew, C. G., Jackson, A. & Stewart, G. S. Apr 2017 In : Nature Genetics.

    Research output: Contribution to journalArticle

  5. 2016
  6. Type I interferon causes thrombotic microangiopathy by a dose-dependent toxic effect on the microvasculature

    Kavanagh, D. , McGlasson, S. , Jury, A. , Williams, J. , Scolding, N. , Bellamy, C. , Gunther, C. , Ritchie, D. , Gale, D. P. , Kanwar, Y. S. , Challis, R. , Buist, H. , Overell, J. , Weller, B. , Flossmann, O. , Blunden, M. , Meyer, E. P. , Krucker, T. , Evans, S. J. W. , Campbell, I. L. & 3 others Jackson, A. P., Chandran, S. & Hunt, D. P. J. 23 Sep 2016 In : Blood.

    Research output: Contribution to journalArticle

  7. 2014
  8. Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN

    Wong, E. K. S., Anderson, H. E., Herbert, A. P., Challis, R. C., Brown, P., Reis, G. S., Tellez, J. O., Strain, L., Fluck, N., Humphrey, A., Macleod, A., Richards, A., Ahlert, D., Santibanez-Koref, M., Barlow, P. N., Marchbank, K. J., Harris, C. L., Goodship, T. H. J. & Kavanagh, D. Nov 2014 In : Journal of the American Society of Nephrology. 25, 11, p. 2425-33 9 p.

    Research output: Contribution to journalArticle